Family: Ribonuclease PH domain 1-like

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a+b) [53931]
   Mainly antiparallel beta sheets (segregated alpha and beta regions)
3. Fold: Ribosomal protein S5 domain 2-like [54210]
   core: beta(3)-alpha-beta-alpha; 2 layers: alpha/beta; left-handed crossover
4. Superfamily: Ribosomal protein S5 domain 2-like [54211]
   uperfamily
5. Family: Ribonuclease PH domain 1-like [54229]

Protein Domains:

1. Ribonuclease PH, domain 1 [102758]
   1. Aquifex aeolicus [TaxId: 63363] [102759] (4)
      1. 1uds
         complexed with po4, so4; mutant
         1. region a:2-150 [99219]
      2. 1udq
         complexed with po4, so4; mutant
         1. region a:2-150 [99217]
      3. 1udo
         complexed with po4, so4; mutant
         1. region a:2-150 [99215]
      4. 1udn
         complexed with po4, so4
         1. region a:2-150 [99213]
   2. Pseudomonas aeruginosa [TaxId: 287] [102760] (2)
      1. 1r6l
         complexed with nhe, so4
         1. region a:1-151 [97153]
      2. 1r6m
         complexed with po4
         1. region a:1-151 [97155]
   3. Bacillus subtilis [TaxId: 1423] [102761] (3)
      1. 1oys
         mutant
         1. region a:1-151 [93758]
      2. 1oyp
         complexed with sul
         1. region a:1-151 [93734]
         2. region b:1-151 [93736]
         3. region c:1-151 [93738]
         4. region d:1-151 [93740]
         5. region e:1-151 [93742]
         6. region f:1-151 [93744]
      3. 1oyr
         complexed with cd, sul
         1. region a:1-151 [93746]
         2. region b:1-151 [93748]
         3. region c:1-151 [93750]
         4. region d:1-151 [93752]
         5. region e:1-151 [93754]
         6. region f:1-151 [93756]
2. Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4 [54230]
   duplication of two-domain units formed by domains 1-2 and 4-5
   1. Streptomyces antibioticus [TaxId: 1890] [54231] (2)
      1. 1e3h
         complexed with so4
         1. region a:3-151 [37572]
         2. region a:346-482 [37573]
      2. 1e3p
         complexed with so4, wo4
         1. region a:3-151 [37574]
         2. region a:346-482 [37575]
3. Exosome complex exonuclease RRP42 [159908]
   1. Human (Homo sapiens) [TaxId: 9606] [159909] (1)
      SQ Q15024 5-191
      1. 2nn6
         mutant
         1. region e:5-191 [148303]
4. Exosome complex exonuclease RRP46 [159910]
   1. Human (Homo sapiens) [TaxId: 9606] [159911] (1)
      SQ Q9NQT4 25-146
      1. 2nn6
         mutant
         1. region d:25-146 [148301]
5. Exosome complex exonuclease RRP45 [159912]
   1. Human (Homo sapiens) [TaxId: 9606] [159913] (1)
      SQ Q86Y41 1-184
      1. 2nn6
         mutant
         1. region a:1-184 [148295]
6. Exosome complex exonuclease RRP43 [159914]
   1. Human (Homo sapiens) [TaxId: 9606] [159915] (1)
      SQ Q96B26 7-187
      1. 2nn6
         mutant
         1. region c:7-187 [148299]
7. Exosome complex exonuclease MTR3 [159916]
   1. Human (Homo sapiens) [TaxId: 9606] [159917] (1)
      SQ Q5RKV6 29-175
      1. 2nn6
         mutant
         1. region f:29-175 [148305]
8. Exosome complex exonuclease RRP41 [159918]
   1. Human (Homo sapiens) [TaxId: 9606] [159919] (1)
      SQ Q9NPD3 7-151
      1. 2nn6
         mutant
         1. region b:6-150 [148297]
9. Exosome complex exonuclease 2,ECX2 [159920]
   1. Archaeoglobus fulgidus [TaxId: 2234] [159921] (6)
      SQ O29756 3-178
      1. 2ba0
         1. region g:3-178 [146111]
      2. 2ba0
         automatically matched to 2BA0 G:3-178
         1. region h:3-178 [146113]
      3. 2ba0
         automatically matched to 2BA0 G:3-178
         1. region i:3-178 [146115]
      4. 2ba1
         automatically matched to 2BA0 G:3-178
         complexed with zn
         1. region g:3-178 [146123]
      5. 2ba1
         automatically matched to 2BA0 G:3-178
         complexed with zn
         1. region h:3-178 [146125]
      6. 2ba1
         automatically matched to 2BA0 G:3-178
         complexed with zn
         1. region i:3-178 [146127]
   2. Sulfolobus solfataricus [TaxId: 2287] [159922] (51)
      SQ Q9UXC0 1-191
      1. 2je6
         complexed with 1pe, cl, peg; mutant
         1. region a:1-191 [147991]
      2. 2jea
         automatically matched to 2JE6 A:1-191
         complexed with 1pe; mutant
         1. region a:1-191 [148008]
      3. 2jeb
         automatically matched to 2JE6 A:1-191
         complexed with 1pe, cl, mn; mutant
         1. region a:1-191 [148015]
      4. 2br2
         automatically matched to 2JE6 A:1-191
         complexed with cl
         1. region a:1-191 [146165]
      5. 2br2
         automatically matched to 2JE6 A:1-191
         complexed with cl
         1. region c:1-191 [146169]
      6. 2br2
         automatically matched to 2JE6 A:1-191
         complexed with cl
         1. region e:1-191 [146173]
      7. 2br2
         automatically matched to 2JE6 A:1-191
         complexed with cl
         1. region g:1-191 [146177]
      8. 2br2
         automatically matched to 2JE6 A:1-191
         complexed with cl
         1. region i:1-191 [146181]
      9. 2br2
         automatically matched to 2JE6 A:1-191
         complexed with cl
         1. region k:1-191 [146185]
      10. 2br2
          automatically matched to 2JE6 A:1-191
          complexed with cl
          1. region m:1-191 [146189]
      11. 2br2
          automatically matched to 2JE6 A:1-191
          complexed with cl
          1. region o:1-191 [146193]
      12. 2br2
          automatically matched to 2JE6 A:1-191
          complexed with cl
          1. region q:1-191 [146197]
      13. 2br2
          automatically matched to 2JE6 A:1-191
          complexed with cl
          1. region s:1-191 [146201]
      14. 2br2
          automatically matched to 2JE6 A:1-191
          complexed with cl
          1. region u:1-191 [146205]
      15. 2br2
          automatically matched to 2JE6 A:1-191
          complexed with cl
          1. region w:1-191 [146209]
      16. 2c37
          automatically matched to 2JE6 A:1-191
          complexed with cl, na, rp5, u5p
          1. region a:1-191 [146228]
      17. 2c37
          automatically matched to 2JE6 A:1-191
          complexed with cl, na, rp5, u5p
          1. region c:1-191 [146232]
      18. 2c37
          automatically matched to 2JE6 A:1-191
          complexed with cl, na, rp5, u5p
          1. region e:1-191 [146236]
      19. 2c37
          automatically matched to 2JE6 A:1-191
          complexed with cl, na, rp5, u5p
          1. region g:1-191 [146240]
      20. 2c37
          automatically matched to 2JE6 A:1-191
          complexed with cl, na, rp5, u5p
          1. region i:1-191 [146244]
      21. 2c37
          automatically matched to 2JE6 A:1-191
          complexed with cl, na, rp5, u5p
          1. region k:1-191 [146248]
      22. 2c37
          automatically matched to 2JE6 A:1-191
          complexed with cl, na, rp5, u5p
          1. region m:1-191 [146252]
      23. 2c37
          automatically matched to 2JE6 A:1-191
          complexed with cl, na, rp5, u5p
          1. region o:1-191 [146256]
      24. 2c37
          automatically matched to 2JE6 A:1-191
          complexed with cl, na, rp5, u5p
          1. region q:1-191 [146260]
      25. 2c37
          automatically matched to 2JE6 A:1-191
          complexed with cl, na, rp5, u5p
          1. region s:1-191 [146264]
      26. 2c37
          automatically matched to 2JE6 A:1-191
          complexed with cl, na, rp5, u5p
          1. region u:1-191 [146268]
      27. 2c37
          automatically matched to 2JE6 A:1-191
          complexed with cl, na, rp5, u5p
          1. region w:1-191 [146272]
      28. 2c38
          automatically matched to 2JE6 A:1-191
          complexed with amp, cl
          1. region a:1-191 [146276]
      29. 2c38
          automatically matched to 2JE6 A:1-191
          complexed with amp, cl
          1. region c:1-191 [146280]
      30. 2c38
          automatically matched to 2JE6 A:1-191
          complexed with amp, cl
          1. region e:1-191 [146284]
      31. 2c38
          automatically matched to 2JE6 A:1-191
          complexed with amp, cl
          1. region g:1-191 [146288]
      32. 2c38
          automatically matched to 2JE6 A:1-191
          complexed with amp, cl
          1. region i:1-191 [146292]
      33. 2c38
          automatically matched to 2JE6 A:1-191
          complexed with amp, cl
          1. region k:1-191 [146296]
      34. 2c38
          automatically matched to 2JE6 A:1-191
          complexed with amp, cl
          1. region m:1-191 [146300]
      35. 2c38
          automatically matched to 2JE6 A:1-191
          complexed with amp, cl
          1. region o:1-191 [146304]
      36. 2c38
          automatically matched to 2JE6 A:1-191
          complexed with amp, cl
          1. region q:1-191 [146308]
      37. 2c38
          automatically matched to 2JE6 A:1-191
          complexed with amp, cl
          1. region s:1-191 [146312]
      38. 2c38
          automatically matched to 2JE6 A:1-191
          complexed with amp, cl
          1. region u:1-191 [146316]
      39. 2c38
          automatically matched to 2JE6 A:1-191
          complexed with amp, cl
          1. region w:1-191 [146320]
      40. 2c39
          automatically matched to 2JE6 A:1-191
          complexed with adp
          1. region a:1-191 [146324]
      41. 2c39
          automatically matched to 2JE6 A:1-191
          complexed with adp
          1. region c:1-191 [146328]
      42. 2c39
          automatically matched to 2JE6 A:1-191
          complexed with adp
          1. region e:1-191 [146332]
      43. 2c39
          automatically matched to 2JE6 A:1-191
          complexed with adp
          1. region g:1-191 [146336]
      44. 2c39
          automatically matched to 2JE6 A:1-191
          complexed with adp
          1. region i:1-191 [146338]
      45. 2c39
          automatically matched to 2JE6 A:1-191
          complexed with adp
          1. region k:1-191 [146342]
      46. 2c39
          automatically matched to 2JE6 A:1-191
          complexed with adp
          1. region m:1-191 [146346]
      47. 2c39
          automatically matched to 2JE6 A:1-191
          complexed with adp
          1. region o:1-191 [146350]
      48. 2c39
          automatically matched to 2JE6 A:1-191
          complexed with adp
          1. region q:1-191 [146354]
      49. 2c39
          automatically matched to 2JE6 A:1-191
          complexed with adp
          1. region s:1-191 [146358]
      50. 2c39
          automatically matched to 2JE6 A:1-191
          complexed with adp
          1. region u:1-191 [146362]
      51. 2c39
          automatically matched to 2JE6 A:1-191
          complexed with adp
          1. region w:1-191 [146366]
10. Exosome complex exonuclease 1, ECX1 [159923]
    1. Sulfolobus solfataricus [TaxId: 2287] [159924] (50)
       SQ Q9UXC2 8-155
       1. 2je6
          complexed with 1pe, cl, peg; mutant
          1. region b:8-155 [147993]
       2. 2jea
          automatically matched to 2JE6 B:8-155
          complexed with 1pe; mutant
          1. region b:8-155 [148010]
       3. 2jeb
          automatically matched to 2JE6 B:8-155
          complexed with 1pe, cl, mn; mutant
          1. region b:9-155 [148017]
       4. 2br2
          complexed with cl
          1. region b:8-155 [146167]
       5. 2br2
          automatically matched to 2BR2 B:8-155
          complexed with cl
          1. region d:8-155 [146171]
       6. 2br2
          automatically matched to 2BR2 B:8-155
          complexed with cl
          1. region f:8-155 [146175]
       7. 2br2
          automatically matched to 2BR2 B:8-155
          complexed with cl
          1. region h:8-155 [146179]
       8. 2br2
          automatically matched to 2BR2 B:8-155
          complexed with cl
          1. region j:8-155 [146183]
       9. 2br2
          automatically matched to 2BR2 B:8-155
          complexed with cl
          1. region l:8-155 [146187]
       10. 2br2
           automatically matched to 2BR2 B:8-155
           complexed with cl
           1. region n:8-155 [146191]
       11. 2br2
           automatically matched to 2BR2 B:8-155
           complexed with cl
           1. region p:8-155 [146195]
       12. 2br2
           automatically matched to 2BR2 B:8-155
           complexed with cl
           1. region r:8-155 [146199]
       13. 2br2
           automatically matched to 2BR2 B:8-155
           complexed with cl
           1. region t:8-155 [146203]
       14. 2br2
           automatically matched to 2BR2 B:8-155
           complexed with cl
           1. region v:8-155 [146207]
       15. 2br2
           automatically matched to 2BR2 B:8-155
           complexed with cl
           1. region x:8-155 [146211]
       16. 2c37
           automatically matched to 2BR2 B:8-155
           complexed with cl, na, rp5, u5p
           1. region b:8-155 [146230]
       17. 2c37
           automatically matched to 2BR2 B:8-155
           complexed with cl, na, rp5, u5p
           1. region d:8-155 [146234]
       18. 2c37
           automatically matched to 2BR2 B:8-155
           complexed with cl, na, rp5, u5p
           1. region f:8-155 [146238]
       19. 2c37
           automatically matched to 2BR2 B:8-155
           complexed with cl, na, rp5, u5p
           1. region h:8-155 [146242]
       20. 2c37
           automatically matched to 2BR2 B:8-155
           complexed with cl, na, rp5, u5p
           1. region j:8-155 [146246]
       21. 2c37
           automatically matched to 2BR2 B:8-155
           complexed with cl, na, rp5, u5p
           1. region l:8-155 [146250]
       22. 2c37
           automatically matched to 2BR2 B:8-155
           complexed with cl, na, rp5, u5p
           1. region n:8-155 [146254]
       23. 2c37