Structural Classification of Proteins

Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain

: family members also share a common alpha+beta fold in C-terminal domain

Lineage:

Root: scop
Class: Alpha and beta proteins (a/b) [51349]
Mainly parallel beta sheets (beta-alpha-beta units)
Fold: NAD(P)-binding Rossmann-fold domains [51734]
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar
Superfamily: NAD(P)-binding Rossmann-fold domains [51735]
uperfamily
Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800]
family members also share a common alpha+beta fold in C-terminal domain

Protein Domains:

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) [51801]
1. Escherichia coli [TaxId: 562] [51802] (13)
  SQ P06977
  1. 1gad
    complexed with nad
    1. region o:0-148,o:313-330 [29950]
    2. region p:0-148,p:313-330 [29951]
  2. 2vyn
    automatically matched to d1dc3a1
    complexed with fmt, nad
    1. region a:0-147,a:312-329 [153707]
  3. 2vyn
    automatically matched to d1dc3a1
    complexed with fmt, nad
    1. region b:0-147,b:312-329 [153709]
  4. 2vyn
    automatically matched to d1dc3a1
    complexed with fmt, nad
    1. region c:0-147,c:312-329 [153711]
  5. 1s7c
    complexed with mes, so4
    1. region a:2-148,a:313-331 [105346]
  6. 1gae
    complexed with nad; mutant
    1. region o:0-148,o:313-330 [29954]
    2. region p:0-148,p:313-330 [29955]
  7. 2vyv
    automatically matched to d1dc3a1
    complexed with 1gp, fmt, nad
    1. region a:0-147,a:312-329 [153715]
  8. 2vyv
    automatically matched to d1dc3a1
    complexed with 1gp, fmt, nad
    1. region b:0-147,b:312-329 [153717]
  9. 2vyv
    automatically matched to d1dc3a1
    complexed with 1gp, fmt, nad
    1. region c:0-147,c:312-329 [153719]
  10. 1dc5
    1. region a:0-148,a:313-330 [29952]
    2. region b:0-148,b:313-330 [29953]
  11. 1dc6
    complexed with nad
    1. region a:0-148,a:313-330 [29956]
    2. region b:0-148,b:313-330 [29957]
  12. 1dc3
    1. region a:0-148,a:313-330 [29958]
    2. region b:0-148,b:313-330 [29959]
  13. 1dc4
    complexed with g3h
    1. region a:0-148,a:313-330 [29960]
    2. region b:0-148,b:313-330 [29961]
2. Bacillus stearothermophilus, nca 1503 [TaxId: 1422] [51803] (14)
  1. 3cmc
    automatically matched to d1gd1o1
    complexed with edo, g3h, gol, nad, so4
    1. region o:0-148,o:313-333 [156800]
  2. 3cmc
    automatically matched to d1gd1o1
    complexed with edo, g3h, gol, nad, so4
    1. region p:0-148,p:313-333 [156802]
  3. 3cmc
    automatically matched to d1gd1o1
    complexed with edo, g3h, gol, nad, so4
    1. region q:0-148,q:313-333 [156804]
  4. 3cmc
    automatically matched to d1gd1o1
    complexed with edo, g3h, gol, nad, so4
    1. region r:0-148,r:313-333 [156806]
  5. 1gd1
    complexed with nad, so4
    1. region o:0-148,o:313-333 [29962]
    2. region p:0-148,p:313-333 [29963]
    3. region q:0-148,q:313-333 [29964]
    4. region r:0-148,r:313-333 [29965]
  6. 1nqo
    complexed with g3h, nad; mutant
    1. region a:0-148,a:313-333 [86044]
    2. region c:0-148,c:313-333 [86046]
    3. region o:0-148,o:313-333 [86048]
    4. region q:0-148,q:313-333 [86050]
  7. 1npt
    complexed with nad, so4; mutant
    1. region o:0-148,o:313-333 [85987]
    2. region p:0-148,p:313-333 [85989]
    3. region q:0-148,q:313-333 [85991]
    4. region r:0-148,r:313-333 [85993]
  8. 1nq5
    complexed with nad, so4; mutant
    1. region a:0-148,a:313-333 [86008]
    2. region c:0-148,c:313-333 [86010]
    3. region o:0-148,o:313-333 [86012]
    4. region q:0-148,q:313-333 [86014]
  9. 1nqa
    complexed with g3h, nad; mutant
    1. region o:0-148,o:313-333 [86016]
    2. region p:0-148,p:313-333 [86018]
    3. region q:0-148,q:313-333 [86020]
    4. region r:0-148,r:313-333 [86022]
  10. 1dbv
    complexed with nad, so4; mutant
    1. region o:0-148,o:313-333 [29966]
    2. region p:0-148,p:313-333 [29967]
    3. region q:0-148,q:313-333 [29968]
    4. region r:0-148,r:313-333 [29969]
  11. 4dbv
    complexed with ndp, so4; mutant
    1. region o:0-148,o:313-333 [29974]
    2. region p:0-148,p:313-333 [29975]
    3. region q:0-148,q:313-333 [29976]
    4. region r:0-148,r:313-333 [29977]
  12. 2dbv
    complexed with ndp, so4; mutant
    1. region o:0-148,o:313-333 [29970]
    2. region p:0-148,p:313-333 [29971]
    3. region q:0-148,q:313-333 [29972]
    4. region r:0-148,r:313-333 [29973]
  13. 2gd1
    complexed with so4
    1. region o:0-148,o:313-333 [29978]
    2. region p:0-148,p:313-333 [29979]
    3. region q:0-148,q:313-333 [29980]
    4. region r:0-148,r:313-333 [29981]
  14. 3dbv
    complexed with nad, so4; mutant
    1. region o:0-148,o:313-333 [29982]
    2. region p:0-148,p:313-333 [29983]
    3. region q:0-148,q:313-333 [29984]
    4. region r:0-148,r:313-333 [29985]
3. Achromobacter xylosoxidans [TaxId: 85698] [89526] (1)
  formerly Alcaligenes xylosoxidans
  1. 1obf
    complexed with csw, k, pg4, so4
    1. region o:1-152,o:315-335 [86768]
    2. region p:1-152,p:315-335 [86770]
4. Thermus aquaticus [TaxId: 271] [51804] (13)
  1. 2g82
    automatically matched to d1cero1
    complexed with gol, ipa, na, nad, pge
    1. region a:1-148,a:311-330 [134746]
  2. 2g82
    automatically matched to d1cero1
    complexed with gol, ipa, na, nad, pge
    1. region b:1-148,b:311-330 [134748]
  3. 2g82
    automatically matched to d1cero1
    complexed with gol, ipa, na, nad, pge
    1. region c:1-148,c:311-330 [134750]
  4. 2g82
    automatically matched to d1cero1
    complexed with gol, ipa, na, nad, pge
    1. region d:1-148,d:311-330 [134752]
  5. 2g82
    automatically matched to d1cero1
    complexed with gol, ipa, na, nad, pge
    1. region o:1-148,o:311-330 [134754]
  6. 2g82
    automatically matched to d1cero1
    complexed with gol, ipa, na, nad, pge
    1. region p:1-148,p:311-330 [134756]
  7. 2g82
    automatically matched to d1cero1
    complexed with gol, ipa, na, nad, pge
    1. region q:1-148,q:311-330 [134758]
  8. 2g82
    automatically matched to d1cero1
    complexed with gol, ipa, na, nad, pge
    1. region r:1-148,r:311-330 [134760]
  9. 1cer
    complexed with nad
    1. region o:1-148,o:313-333 [29986]
    2. region q:1-148,q:313-333 [29987]
    3. region p:1-148,p:313-333 [29988]
    4. region r:1-148,r:313-333 [29989]
  10. 1cer
    duplicate of 1CER O:1-148,O:313-333
    complexed with nad
    1. region a:1-148,a:313-333 [118442]
  11. 1cer
    duplicate of 1CER O:1-148,O:313-333
    complexed with nad
    1. region b:1-148,b:313-333 [118444]
  12. 1cer
    duplicate of 1CER O:1-148,O:313-333
    complexed with nad
    1. region c:1-148,c:313-333 [118446]
  13. 1cer
    duplicate of 1CER O:1-148,O:313-333
    complexed with nad
    1. region d:1-148,d:313-333 [118448]
5. Thermus thermophilus [TaxId: 274] [102157] (1)
  1. 1vc2
    complexed with nad
    1. region a:1-148,a:311-331 [100555]
6. Thermotoga maritima [TaxId: 2336] [51805] (1)
  1. 1hdg
    complexed with nad, so4
    1. region o:1-148,o:313-331 [29990]
    2. region q:1-148,q:313-331 [29991]
7. Archaeon Sulfolobus solfataricus [TaxId: 2287] [51806] (1)
  1. 1b7g
    CASP3
    complexed with so4; mutant
    1. region o:1-138,o:301-340 [29992]
    2. region q:1-138,q:301-340 [29993]
8. Archaeon Methanothermus fervidus [TaxId: 2180] [51807] (1)
  1. 1cf2
    complexed with nap, so4
    1. region o:1-138,o:304-336 [29994]
    2. region q:1-138,q:304-336 [29995]
    3. region p:1-138,p:304-336 [29996]
    4. region r:1-138,r:304-336 [29997]
9. Trypanosoma brucei brucei, glycosome [TaxId: 5702] [51808] (1)
  1. 1gga
    complexed with nad, so4
    1. region o:1-164,o:334-358 [29998]
    2. region p:1-164,p:334-358 [29999]
    3. region q:1-164,q:334-358 [30000]
    4. region r:1-164,r:334-358 [30001]
    5. region a:1-164,a:334-358 [30002]
    6. region b:1-164,b:334-358 [30003]
10. Trypanosoma cruzi [TaxId: 5693] [75104] (7)
  1. 1k3t
    complexed with brz
    1. region a:1-164,a:334-359 [72022]
    2. region b:1-164,b:334-359 [72024]
    3. region c:1-164,c:334-359 [72026]
    4. region d:1-164,d:334-359 [72028]
  2. 3dmt
    automatically matched to d1k3ta1
    complexed with gol, nad
    1. region a:1-164,a:334-359 [157807]
  3. 3dmt
    automatically matched to d1k3ta1
    complexed with gol, nad
    1. region b:1-164,b:334-359 [157809]
  4. 3dmt
    automatically matched to d1k3ta1
    complexed with gol, nad
    1. region c:1-164,c:334-359 [157811]
  5. 3dmt
    automatically matched to d1k3ta1
    complexed with gol, nad
    1. region d:1-164,d:334-359 [157813]
  6. 1ml3
    complexed with cyx, nad
    1. region a:1-164,a:334-359 [85001]
    2. region b:1-164,b:334-359 [85003]
    3. region c:1-164,c:334-359 [85005]
    4. region d:1-164,d:334-359 [85007]
  7. 1qxs
    complexed with nad, s70
    1. region a:1-164,a:334-359 [96554]
    2. region b:1-164,b:334-359 [96556]
    3. region c:1-164,c:334-359 [96558]
    4. region d:1-164,d:334-359 [96560]
11. Leishmania mexicana [TaxId: 5665] [51809] (5)
  1. 1i32
    complexed with nmd
    1. region a:1-165,a:335-358 [65993]
    2. region b:1-165,b:335-358 [65995]
    3. region c:1-165,c:335-358 [65997]
    4. region d:1-165,d:335-358 [65999]
    5. region e:1-165,e:335-358 [66001]
    6. region f:1-165,f:335-358 [66003]
  2. 1gyp
    complexed with nad, po4
    1. region a:1-165,a:335-358 [30004]
    2. region b:1-165,b:335-358 [30005]
    3. region c:1-165,c:335-358 [30006]
    4. region d:1-165,d:335-358 [30007]
  3. 1i33
    complexed with tnd
    1. region a:1-165,a:335-358 [66005]
    2. region b:1-165,b:335-358 [66007]
    3. region c:1-165,c:335-358 [66009]
    4. region d:1-165,d:335-358 [66011]
    5. region e:1-165,e:335-358 [66013]
    6. region f:1-165,f:335-358 [66015]
  4. 1a7k
    complexed with nad, po4
    1. region a:1-165,a:335-358 [30008]
    2. region b:1-165,b:335-358 [30009]
    3. region c:1-165,c:335-358 [30010]
    4. region d:1-165,d:335-358 [30011]
  5. 1gyq
    complexed with nbd
    1. region a:1-165,a:335-358 [30012]
    2. region b:1-165,b:335-358 [30013]
    3. region c:1-165,c:335-358 [30014]
    4. region d:1-165,d:335-358 [30015]
12. American lobster (Homarus americanus) [TaxId: 6706] [51810] (2)
  1. 4gpd
    1. region 1:1-147,1:312-333 [30016]
    2. region 2:1-147,2:312-333 [30017]
    3. region 3:1-147,3:312-333 [30018]
    4. region 4:1-147,4:312-333 [30019]
  2. 1gpd
    complexed with ips, nad, sps
    1. region g:1-148,g:313-334 [30020]
    2. region r:1-148,r:313-334 [30021]
13. South China Sea lobster (Palinurus versicolor) [TaxId: 150436] [51811] (5)
  1. 1dss
    complexed with nad, so4
    1. region g:1-148,g:313-334 [30022]
    2. region r:1-148,r:313-334 [30023]
  2. 1szj
    complexed with nad, so4
    1. region g:1-148,g:313-334 [30024]
    2. region r:1-148,r:313-334 [30025]
  3. 1crw
    1. region g:1-148,g:313-334 [30026]
    2. region r:1-148,r:313-334 [30027]
  4. 1ihx
    complexed with snd, so4
    1. region a:1-148,a:313-334 [71211]
    2. region b:1-148,b:313-334 [71213]
    3. region c:1-148,c:313-334 [71215]
    4. region d:1-148,d:313-334 [71217]
  5. 1ihy
    complexed with apr, so4
    1. region a:1-148,a:313-334 [71219]
    2. region b:1-148,b:313-334 [71221]
    3. region c:1-148,c:313-334 [71223]
    4. region d:1-148,d:313-334 [71225]
14. Human (Homo sapiens) [TaxId: 9606] [51812] (1)
  1. 3gpd
    complexed with ips, nad, sps
    1. region r:1-150,r:315-334 [30028]
    2. region g:1-150,g:315-334 [30029]
15. Rabbit (Oryctolagus cuniculus) [TaxId: 9986] [102158] (1)
  1. 1j0x
    complexed with nad
    1. region o:1-148,o:313-332 [90750]
    2. region p:1-148,p:313-332 [90752]
    3. region q:1-148,q:313-332 [90754]
    4. region r:1-148,r:313-332 [90756]
16. Spinach (Spinacia oleracea) [TaxId: 3562] [69409] (24)
  SQ P19866
  1. 1rm4
    complexed with ndp, so4
    1. region a:1-148,a:313-333 [105000]
    2. region b:1-148,b:313-333 [105002]
    3. region o:1-148,o:313-333 [105004]
  2. 1rm5
    complexed with ndp, so4; mutant
    1. region a:1-148,a:313-333 [105006]
    2. region b:1-148,b:313-333 [105008]
    3. region o:1-148,o:313-333 [105010]
  3. 1rm3
    complexed with ndp, so4; mutant
    1. region a:1-148,a:313-333 [104994]
    2. region b:1-148,b:313-333 [104996]
    3. region o:1-148,o:313-333 [104998]
  4. 1nbo
    complexed with nad, so4
    1. region o:0-148,o:313-334 [85530]
    2. region a:0-148,a:313-334 [85526]
    3. region b:0-148,b:313-333 [85528]
  5. 2pkr
    automatically matched to d1nboa1
    complexed with ndp, so4
    1. region a:0-148,a:313-333 [139716]
  6. 2pkr
    automatically matched to d1nboa1
    complexed with ndp, so4
    1. region b:0-148,b:313-333 [139718]
  7. 2pkr
    automatically matched to d1nboa1
    complexed with ndp, so4
    1. region c:0-148,c:313-333 [139720]
  8. 2pkr
    automatically matched to d1nboa1
    complexed with ndp, so4
    1. region d:0-148,d:313-333 [139722]
  9. 2pkr
    automatically matched to d1nboa1
    complexed with ndp, so4
    1. region h:0-148,h:313-333 [139724]
  10. 2pkr
    automatically matched to d1nboa1
    complexed with ndp, so4
    1. region i:0-148,i:313-333 [139726]
  11. 2pkr
    automatically matched to d1nboa1
    complexed with ndp, so4
    1. region l:0-148,l:313-333 [139728]
  12. 2pkr
    automatically matched to d1nboa1
    complexed with ndp, so4
    1. region m:0-148,m:313-333 [139730]
  13. 2pkr
    automatically matched to d1nboa1
    complexed with ndp, so4
    1. region o:0-148,o:313-333 [139732]
  14. 2pkr
    automatically matched to d1nboa1
    complexed with ndp, so4
    1. region p:0-148,p:313-333 [139734]
  15. 2pkr
    automatically matched to d1nboa1
    complexed with ndp, so4
    1. region q:0-148,q:313-333 [139736]
  16. 2pkr
    automatically matched to d1nboa1
    complexed with ndp, so4
    1. region r:0-148,r:313-333 [139738]
  17. 1jn0
    complexed with ndp, so4
    1. region o:0-148,o:313-333 [66919]
    2. region a:0-148,a:313-333 [66915]
    3. region b:0-148,b:313-333 [66917]
  18. 2hki
    automatically matched to d1nboa1
    complexed with so4
    1. region a:1-152,a:316-335 [136551]
  19. 2pkq
    automatically matched to d1nboa1
    complexed with ndp, so4
    1. region p:0-148,p:313-332 [139710]
  20. 2pkq
    automatically matched to d1nboa1
    complexed with ndp, so4
    1. region r:0-148,r:313-332 [139712]
  21. 2pkq
    automatically matched to d1nboa1
    complexed with ndp, so4
    1. region s:0-148,s:313-332 [139714]
  22. 2pkq
    complexed with ndp, so4
    1. region o:0-148,o:313-333 [145748]
  23. 2pkq
    automatically matched to 2PKQ O:0-148,O:313-333
    complexed with ndp, so4
    1. region q:0-148,q:313-333 [145750]
  24. 2pkq
    automatically matched to 2PKQ O:0-148,O:313-333
    complexed with ndp, so4
    1. region t:0-148,t:313-333 [145752]
17. Human(Homo sapiens), liver isoform [TaxId: 9606] [141915] (8)
  SQ P04406 2-150,315-334
  1. 1u8f
    automatically matched to 1ZNQ O:3-151,O:316-335
    complexed with nad
    1. region o:3-151,o:316-335 [119626]
  2. 1u8f
    automatically matched to 1ZNQ O:3-151,O:316-335
    complexed with nad
    1. region p:3-151,p:316-335 [119628]
  3. 1u8f
    automatically matched to 1ZNQ O:3-151,O:316-335
    complexed with nad
    1. region q:3-151,q:316-335 [119630]
  4. 1u8f
    automatically matched to 1ZNQ O:3-151,O:316-335
    complexed with nad
    1. region r:3-151,r:316-335 [119632]
  5. 1znq
    complexed with nad
    1. region o:3-151,o:316-335 [125401]
  6. 1znq
    automatically matched to 1ZNQ O:3-151,O:316-335
    complexed with nad
    1. region p:3-151,p:316-335 [125403]
  7. 1znq
    automatically matched to 1ZNQ O:3-151,O:316-335
    complexed with nad
    1. region q:3-151,q:316-335 [125405]
  8. 1znq
    automatically matched to 1ZNQ O:3-151,O:316-335
    complexed with nad
    1. region r:3-151,r:316-335 [125407]
18. Malaria parasite (Plasmodium falciparum) [TaxId: 5833] [141916] (12)
  SQ Q8IKK7 4-152,319-335! SQ Q8T6B1 1-152,319-337
  1. 2b4r
    complexed with aes, gol, nad; mutant
    1. region o:4-152,o:319-335 [127845]
  2. 2b4r
    automatically matched to 2B4R O:4-152,O:319-335
    complexed with aes, gol, nad; mutant
    1. region p:4-152,p:319-335 [127847]
  3. 2b4r
    automatically matched to 2B4R O:4-152,O:319-335
    complexed with aes, gol, nad; mutant
    1. region q:4-152,q:319-335 [127849]
  4. 2b4r
    automatically matched to 2B4R O:4-152,O:319-335
    complexed with aes, gol, nad; mutant
    1. region r:4-152,r:319-335 [127851]
  5. 2b4t
    automatically matched to 2B4R O:4-152,O:319-335
    complexed with aes, nad; mutant
    1. region o:4-152,o:319-335 [127856]
  6. 2b4t
    automatically matched to 2B4R O:4-152,O:319-335
    complexed with aes, nad; mutant
    1. region p:4-152,p:319-335 [127858]
  7. 2b4t
    automatically matched to 2B4R O:4-152,O:319-335
    complexed with aes, nad; mutant
    1. region q:4-152,q:319-335 [127860]
  8. 2b4t
    automatically matched to 2B4R O:4-152,O:319-335
    complexed with aes, nad; mutant
    1. region r:4-152,r:319-335 [127862]
  9. 1ywg
    complexed with nad
    1. region o:1-152,o:319-337 [124145]
  10. 1ywg
    automatically matched to 1YWG O:1-152,O:319-337
    complexed with nad
    1. region p:1-152,p:319-337 [124147]
  11. 1ywg
    automatically matched to 1YWG O:1-152,O:319-337
    complexed with nad
    1. region q:1-152,q:319-337 [124149]
  12. 1ywg
    automatically matched to 1YWG O:1-152,O:319-337
    complexed with nad
    1. region r:1-152,r:319-337 [124151]
19. Archaeon Pyrococcus horikoshii [TaxId: 53953] [159423] (4)
  SQ O59494 1-139,302-334
  1. 2czc
    complexed with nad, po4
    1. region a:1-139,a:302-334 [145052]
  2. 2czc
    automatically matched to 2CZC A:1-139,A:302-334
    complexed with nad, po4
    1. region b:2-139,b:302-334 [145053]
  3. 2czc
    automatically matched to 2CZC A:1-139,A:302-334
    complexed with nad, po4
    1. region c:2-139,c:302-334 [145055]
  4. 2czc
    automatically matched to 2CZC A:1-139,A:302-334
    complexed with nad, po4
    1. region d:2-139,d:302-333 [145057]
Aspartate beta-semialdehyde dehydrogenase [51813]
1. Escherichia coli [TaxId: 562] [51814] (4)
  SQ P00353
  1. 1t4b
    complexed with na
    1. region a:1-133,a:355-367 [106406]
    2. region b:1-133,b:355-367 [106408]
  2. 1t4d
    1. region a:1-133,a:355-367 [106412]
    2. region b:1-133,b:355-367 [106414]
    3. region c:1-133,c:355-367 [106416]
  3. 1brm
    1. region a:1-133,a:355-367 [30030]
    2. region b:1-133,b:355-367 [30031]
    3. region c:1-133,c:355-367 [30032]
  4. 1gl3
    complexed with cys, ndp
    1. region a:1-133,a:355-367 [65282]
    2. region b:1-133,b:355-367 [65284]
2. Vibrio cholerae [TaxId: 666] [82297] (2)
  1. 1mb4
    complexed with cys, ndp
    1. region a:1-132,a:355-369 [78908]
    2. region b:1-132,b:355-369 [78910]
  2. 1mc4
    1. region a:1-132,a:355-369 [84927]
3. Haemophilus influenzae [TaxId: 727] [102159] (12)
  SQ P44801
  1. 1pqu
    complexed with cac, cys, nap; mutant
    1. region a:1-133,a:358-371 [104288]
    2. region b:1-133,b:358-371 [104290]
    3. region c:1-133,c:358-371 [104292]
    4. region d:1-133,d:358-371 [104294]
  2. 1nwc
    1. region a:1-133,a:358-371 [92229]
    2. region b:1-133,b:358-371 [92231]
  3. 1nwh
    complexed with hti
    1. region a:1-133,a:358-371 [92233]
    2. region b:1-133,b:358-371 [92235]
  4. 1oza
    mutant
    1. region a:1-133,a:358-371 [104045]
  5. 1pqp
    complexed with as2, po4; mutant
    1. region a:1-133,a:358-371 [104286]
  6. 1pu2
    complexed with hti; mutant
    1. region a:1-133,a:358-371 [104308]
  7. 1pr3
    complexed with po4; mutant
    1. region a:1-133,a:358-371 [104300]
  8. 1tb4
    complexed with pej
    1. region a:1-133,a:358-368 [112380]
  9. 1nx6
    complexed with hti, po4
    1. region a:1-133,a:358-371 [92283]
  10. 1q2x
    complexed with hti; mutant
    1. region a:1-133,a:358-371 [104503]
    2. region b:1-133,b:358-371 [104505]
  11. 1ta4
    complexed with art
    1. region a:1-133,a:358-368 [112373]
  12. 1ps8
    mutant
    1. region a:1-133,a:358-371 [104304]
4. Streptococcus pneumoniae [TaxId: 1313] [141917] (11)
  SQ Q8DQ00 2-127,330-357
  1. 2gz1
    automatically matched to 2GYY A:2-127,A:330-357
    complexed with nap
    1. region a:2-127,a:330-357 [135887]
  2. 2gz1
    automatically matched to 2GYY A:2-127,A:330-357
    complexed with nap
    1. region b:2-127,b:330-357 [135889]
  3. 2gyy
    1. region a:2-127,a:330-357 [135879]
  4. 2gyy
    automatically matched to 2GYY A:2-127,A:330-357
    1. region b:2-127,b:330-356 [135881]
  5. 2gyy
    automatically matched to 2GYY A:2-127,A:330-357
    1. region c:2-127,c:330-357 [135883]
  6. 2gyy
    automatically matched to 2GYY A:2-127,A:330-357
    1. region d:3-127,d:330-350 [135885]
  7. 2gz2
    automatically matched to 2GYY A:2-127,A:330-357
    complexed with a2p
    1. region a:2-127,a:330-357 [135891]
  8. 2gz2
    automatically matched to 2GYY A:2-127,A:330-357
    complexed with a2p
    1. region b:2-127,b:330-357 [135893]
  9. 2gz3
    automatically matched to 2GYY A:2-127,A:330-357
    complexed with as2, nap
    1. region a:2-127,a:330-357 [135895]
  10. 2gz3
    automatically matched to 2GYY A:2-127,A:330-357
    complexed with as2, nap
    1. region c:2-127,c:330-357 [135897]
  11. 2gz3
    automatically matched to 2GYY A:2-127,A:330-357
    complexed with as2, nap
    1. region d:2-127,d:330-357 [135899]
Acetaldehyde dehydrogenase (acylating) [89527]
1. Pseudomonas sp. [TaxId: 306] [89528] (1)
  1. 1nvm
    complexed with mn, mpd, nad, oxl, sul
    1. region b:1-131,b:287-312 [86251]
    2. region d:3-131,d:287-310 [86255]
    3. region f:4-131,f:287-312 [86259]
    4. region h:4-131,h:287-310 [86263]
Homoserine dehydrogenase [51815]
1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [51816] (4)
  SQ P31116
  1. 1ebf
    complexed with na, nad
    1. region a:2-150,a:341-359 [30033]
    2. region b:2-150,b:341-359 [30034]
  2. 1ebu
    complexed with hse, na, nda
    1. region a:2-150,a:341-359 [30035]
    2. region b:2-150,b:341-359 [30036]
    3. region c:2-150,c:341-359 [30037]
    4. region d:2-150,d:341-359 [30038]
  3. 1q7g
    complexed with na, nho
    1. region a:2-150,a:341-359 [96038]
    2. region b:2-150,b:341-359 [96040]
  4. 1tve
    complexed with 178
    1. region a:2-150,a:341-359 [107354]
    2. region b:2-150,b:341-359 [107356]
Saccharopine reductase [51817]
1. Rice blast fungus (Magnaporthe grisea) [TaxId: 148305] [51818] (3)
  1. 1e5q
    complexed with ndp
    1. region a:2-124,a:392-450 [30040]
    2. region b:2-124,b:392-450 [30041]
    3. region c:2-124,c:392-450 [30042]
    4. region d:2-124,d:392-450 [30043]
    5. region e:2-124,e:392-450 [30044]
    6. region f:2-124,f:392-450 [30045]
    7. region g:2-124,g:392-450 [30046]
    8. region h:2-124,h:392-450 [30047]
  2. 1ff9
    complexed with so4
    1. region a:2-124,a:392-450 [30039]
  3. 1e5l
    1. region a:2-124,a:392-450 [30048]
    2. region b:2-124,b:392-450 [30049]
Diaminopimelic acid dehydrogenase (DAPDH) [51819]
1. Corynebacterium glutamicum [TaxId: 1718] [51820] (4)
  1. 1f06
    complexed with 2np, ndp
    1. region a:1-118,a:269-320 [59556]
    2. region b:501-618,b:769-820 [59558]
  2. 3dap
    complexed with da3, ndp
    1. region a:1-118,a:269-320 [30051]
    2. region b:1-118,b:269-320 [30052]
  3. 2dap
    complexed with api
    1. region a:1-118,a:269-320 [30050]
  4. 1dap
    complexed with act, ndp
    1. region a:1-118,a:269-320 [30053]
    2. region b:1-118,b:269-320 [30054]
Dihydrodipicolinate reductase [51821]
1. Escherichia coli [TaxId: 562] [51822] (5)
  1. 1dih
    complexed with ndp
    1. region a:2-130,a:241-273 [30056]
  2. 1dru
    complexed with nah
    1. region a:4-130,a:241-273 [30055]
  3. 1drw
    complexed with nhd
    1. region a:2-130,a:241-273 [30057]
  4. 1drv
    complexed with nac
    1. region a:4-130,a:241-273 [30058]
  5. 1arz
    complexed with k, nad, pdc, po4
    1. region a:4-130,a:241-273 [30059]
    2. region b:5-130,b:241-273 [30060]
    3. region c:3-130,c:241-273 [30061]
    4. region d:3-130,d:241-273 [30062]
2. Mycobacterium tuberculosis [TaxId: 1773] [102160] (14)
  1. 1yl7
    automatically matched to d1c3va1
    complexed with mg, nad
    1. region a:2-105,a:215-245 [123625]
  2. 1yl7
    automatically matched to d1c3va1
    complexed with mg, nad
    1. region b:2-105,b:215-245 [123627]
  3. 1yl7
    automatically matched to d1c3va1
    complexed with mg, nad
    1. region c:2-105,c:215-245 [123629]
  4. 1yl7
    automatically matched to d1c3va1
    complexed with mg, nad
    1. region d:2-105,d:215-245 [123631]
  5. 1yl7
    automatically matched to d1c3va1
    complexed with mg, nad
    1. region e:2-105,e:215-245 [123633]
  6. 1yl7
    automatically matched to d1c3va1
    complexed with mg, nad
    1. region f:2-105,f:215-245 [123635]
  7. 1yl7
    automatically matched to d1c3va1
    complexed with mg, nad
    1. region g:2-105,g:215-245 [123637]
  8. 1yl7
    automatically matched to d1c3va1
    complexed with mg, nad
    1. region h:2-105,h:215-245 [123639]
  9. 1yl5
    automatically matched to d1c3va1
    complexed with mg
    1. region a:2-105,a:215-245 [123617]
  10. 1yl5
    automatically matched to d1c3va1
    complexed with mg
    1. region b:2-105,b:215-245 [123619]
  11. 1p9l
    complexed with nad, pdc, pg4
    1. region a:1-105,a:215-245 [94393]
    2. region b:1-105,b:215-245 [94395]
  12. 1c3v
    complexed with ndp, pdc, pg4
    1. region a:501-605,a:715-745 [90411]
    2. region b:1001-1105,b:1215-1245 [90413]
  13. 1yl6
    automatically matched to d1c3va1
    complexed with mg
    1. region a:2-105,a:215-245 [123621]
  14. 1yl6
    automatically matched to d1c3va1
    complexed with mg
    1. region b:2-105,b:215-245 [123623]
3. Thermotoga maritima [TaxId: 2336] [110417] (1)
  SQ Q9X1K8
  1. 1vm6
    Structural genomics target
    complexed with act, edo, nad, pg4
    1. region a:1-96,a:183-214 [118631]
    2. region b:1-96,b:183-213 [108878]
    3. region c:1-96,c:183-214 [118632]
    4. region d:1-96,d:183-213 [108882]
Myo-inositol 1-phosphate synthase [75105]
1. Mycobacterium tuberculosis [TaxId: 1773] [75106] (1)
  1. 1gr0
    complexed with cac, nad, zn
    1. region a:14-200,a:312-367 [70379]
2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [75107] (9)
  SQ P11986
  1. 1p1j
    complexed with cry, nai, po4
    1. region a:9-322,a:438-533 [87687]
    2. region b:10-322,b:438-533 [87689]
  2. 1rm0
    complexed with d6p, mn, nai
    1. region a:10-322,a:438-533 [104990]
    2. region b:10-322,b:438-533 [104992]
  3. 1p1h
    complexed with nad
    1. region a:10-322,a:438-533 [87675]
    2. region b:10-322,b:438-533 [87677]
    3. region c:10-322,c:438-533 [87679]
    4. region d:10-322,d:438-533 [87681]
  4. 1p1k
    complexed with nai
    1. region a:9-322,a:438-533 [87691]
    2. region b:10-322,b:438-533 [87693]
  5. 1la2
    complexed with mse, nad
    1. region a:10-322,a:438-533 [73773]
    2. region b:10-322,b:438-533 [73775]
    3. region c:10-322,c:438-533 [73777]
    4. region d:10-322,d:438-533 [73779]
  6. 1p1i
    complexed with nad
    1. region a:9-322,a:438-533 [87683]
    2. region b:10-322,b:438-533 [87685]
  7. 1p1f
    1. region a:9-322,a:438-533 [87671]
    2. region b:9-322,b:438-533 [87673]
  8. 1jki
    complexed with dg6, nai, nh4
    1. region a:9-322,a:438-533 [71704]
    2. region b:10-322,b:438-533 [71706]
  9. 1jkf
    complexed with nad
    1. region a:11-322,a:438-533 [71700]
    2. region b:10-322,b:438-533 [71702]
3. Archaeoglobus fulgidus [TaxId: 2234] [110418] (1)
  SQ O28480
  1. 1u1i
    complexed with k, nad, po4
    1. region a:1-227,a:333-392 [107582]
    2. region b:401-627,b:733-792 [107584]
    3. region c:801-1027,c:1133-1192 [107586]
    4. region d:1201-1427,d:1533-1592 [107588]
4. Caenorhabditis elegans [TaxId: 6239] [110419] (1)
  SQ Q18664
  1. 1vko
    Structural genomics target
    complexed with cl, iod, k, nad, pop
    1. region a:11-314,a:429-521 [108684]
Hypothetical protein TM1419 [102161]
myo-inositol 1-phosphate synthase-related protein
1. Thermotoga maritima [TaxId: 2336] [102162] (1)
  1. 1vjp
    structural genomics
    complexed with cl, mo2, nad
    1. region a:0-209,a:317-381 [100828]
Hypothetical protein TM1643 [75108]
1. Thermotoga maritima [TaxId: 2336] [75109] (2)
  1. 1j5p
    complexed with nad
    1. region a:-1-108,a:220-241 [83092]
  2. 1h2h
    complexed with mse, nad
    1. region a:1-108,a:220-241 [83058]
1-deoxy-D-xylulose-5-phosphate reductoisomerase [69410]
1. Escherichia coli [TaxId: 562] [69411] (12)
  SQ P45568
  1. 1q0q
    complexed with dxp, ndp
    1. region a:1-125,a:275-300 [104465]
    2. region b:1-125,b:275-300 [104468]
  2. 1q0h
    complexed with cit, fom, ndp
    1. region a:1-125,a:275-300 [104441]
  3. 1jvs
    complexed with mse, ndp, so4
    1. region a:0-125,a:275-300 [77188]
    2. region b:0-125,b:275-300 [77191]
  4. 2egh
    automatically matched to d1jvsa2
    complexed with fom, mg, ndp
    1. region a:0-125,a:275-300 [132122]
  5. 2egh
    automatically matched to d1jvsa2
    complexed with fom, mg, ndp
    1. region b:0-125,b:275-300 [132125]
  6. 1t1r
    complexed with imb, so4
    1. region a:1-125 [106263]
    2. region a:275-300 [106264]
    3. region b:1-125 [106267]
    4. region b:275-300 [106268]
  7. 1t1s
    complexed with cbq, mg, so4
    1. region a:1-125 [106271]
    2. region a:275-300 [106272]
    3. region b:1-125 [106275]
    4. region b:275-300 [106276]
  8. 1q0l
    complexed with fom, ndp
    1. region a:1-125,a:275-300 [104456]
  9. 1ono
    complexed with mw3
    1. region a:1-125,a:275-300 [87160]
    2. region b:1-125,b:275-300 [87163]
  10. 1k5h
    1. region a:1-125,a:275-300 [68193]
    2. region b:1-125,b:275-300 [68196]
    3. region c:1-125,c:275-300 [68199]
  11. 1onn
    1. region a:1-125,a:275-300 [87154]
    2. region b:1-125,b:275-300 [87157]
  12. 1onp
    complexed with fom, mw1
    1. region a:1-125,a:275-300 [87166]
    2. region b:1-125,b:275-300 [87169]
2. Zymomonas mobilis [TaxId: 542] [110420] (2)
  SQ Q9X5F2
  1. 1r0k
    complexed with act
    1. region a:3-126,a:265-290 [104724]
    2. region b:3-126,b:265-290 [104727]
    3. region c:3-126,c:265-290 [104730]
    4. region d:3-126,d:265-290 [104733]
  2. 1r0l
    complexed with ndp
    1. region a:3-126,a:265-290 [104736]
    2. region b:3-126,b:265-290 [104739]
    3. region c:3-126,c:265-290 [104742]
    4. region d:3-126,d:265-290 [104745]
Biliverdin reductase [51823]
1. Rat (Rattus norvegicus) [TaxId: 10116] [51824] (3)
  1. 1lc0
    complexed with po4
    1. region a:2-128,a:247-291 [73823]
  2. 1lc3
    complexed with nah, po4
    1. region a:2-128,a:247-293 [73825]
  3. 1gcu
    1. region a:1-128,a:247-292 [30063]
Glucose-fructose oxidoreductase, N-terminal domain [51825]
1. Zymomonas mobilis [TaxId: 542] [51826] (12)
  1. 1h6d
    complexed with gol, ndp
    1. region a:51-212,a:375-433 [65656]
    2. region b:53-212,b:375-433 [65658]
    3. region c:52-212,c:375-433 [65660]
    4. region d:52-212,d:375-433 [65662]
    5. region e:52-212,e:375-433 [65664]
    6. region f:53-212,f:375-433 [65666]
    7. region g:53-212,g:375-433 [65668]
    8. region h:53-212,h:375-433 [65670]
    9. region i:52-212,i:375-433 [65672]
    10. region j:53-212,j:375-433 [65674]
    11. region k:52-212,k:375-433 [65676]
    12. region l:53-212,l:375-433 [65678]
  2. 1ryd
    automatically matched to d1evja1
    complexed with act, bme, glc, ndp
    1. region a:30-160,a:323-381 [118801]
  3. 1ryd
    automatically matched to d1evja1
    complexed with act, bme, glc, ndp
    1. region b:30-160,b:323-381 [118803]
  4. 1h6c
    complexed with gol, ndp, sin
    1. region a:53-212,a:375-433 [65652]
    2. region b:53-212,b:375-433 [65654]
  5. 1rye
    automatically matched to d1evja1
    complexed with bme, gol, ndp
    1. region a:30-160,a:323-381 [118805]
  6. 1rye
    automatically matched to d1evja1
    complexed with bme, gol, ndp
    1. region b:30-160,b:323-381 [118807]
  7. 1rye
    automatically matched to d1evja1
    complexed with bme, gol, ndp
    1. region c:30-160,c:323-381 [118809]
  8. 1rye
    automatically matched to d1evja1
    complexed with bme, gol, ndp
    1. region d:30-160,d:323-381 [118811]
  9. 1h6a
    complexed with ndp
    1. region a:53-212,a:375-433 [65644]
    2. region b:53-212,b:375-433 [65646]
  10. 1h6b
    complexed with gol, ndp
    1. region a:53-212,a:375-433 [65648]
    2. region b:53-212,b:375-433 [65650]
  11. 1evj
    complexed with nad; mutant
    1. region a:30-160,a:323-381 [30070]
    2. region b:30-160,b:323-381 [30071]
    3. region c:30-160,c:323-381 [30072]
    4. region d:30-160,d:323-381 [30073]
  12. 1ofg
    complexed with ndp
    1. region a:1-160,a:323-381 [30064]
    2. region b:1-160,b:323-381 [30065]
    3. region c:1-160,c:323-381 [30066]
    4. region d:1-160,d:323-381 [30067]
    5. region e:1-160,e:323-381 [30068]
    6. region f:1-160,f:323-381 [30069]
Glucose 6-phosphate dehydrogenase, N-terminal domain [51827]
1. Leuconostoc mesenteroides [TaxId: 1245] [51828] (9)
  1. 1h9a
    complexed with nap, so4; mutant
    1. region a:1-181,a:413-426 [60816]
  2. 1dpg
    complexed with po4; mutant
    1. region a:1-181,a:413-426 [30074]
    2. region b:1-181,b:413-426 [30075]
  3. 1h93
    complexed with ca, gol; mutant
    1. region a:1-181,a:413-426 [60807]
  4. 2dpg
    complexed with nap; mutant
    1. region a:1-181,a:413-426 [30076]
  5. 1h9b
    complexed with so4; mutant
    1. region a:1-181,a:413-426 [60818]
  6. 1e7y
    complexed with bg6, ca, ndp; mutant
    1. region a:1-181,a:413-426 [30077]
  7. 1e77