Structural Classification of Proteins
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Changes in domain definitions and classification
Release 1.73 ---> 1.75

Root: scop

Classes:

  1. All alpha proteins [46456] (1)
    1. Globin-like [46457] (1)
      1. Globin-like [46458] (1)
        1. Globins [46463] (1)
          1. Hemoglobin, beta-chain [46500]
            1. Horse (Equus caballus) [TaxId: 9796] [46504] (1) picpic
  2. All beta proteins [48724] (4)
    1. Immunoglobulin-like beta-sandwich [48725] (1)
      1. Purple acid phosphatase, N-terminal domain [49363] (1)
        1. Purple acid phosphatase, N-terminal domain [49364] (1)
          1. Purple acid phosphatase, N-terminal domain [49365]
            1. Sweet potato (Ipomoea batatas) [TaxId: 4120] [117063] (1) picpic
    2. Split barrel-like [50474] (1)
      1. FMN-binding split barrel [50475] (1)
        1. PNP-oxidase like [50476] (1)
          1. NimA-related protein DR0842 [117228]
            1. Deinococcus radiodurans [TaxId: 1299] [117229] (4) picpic
    3. Trypsin-like serine proteases [50493] (1)
      1. Trypsin-like serine proteases [50494] (1)
        1. Viral proteases [50596] (1)
          1. NS3 protease [50600]
            1. Human hepatitis C virus (HCV), different isolates [TaxId: 11103] [50601] (2) picpic
    4. Double-stranded beta-helix [51181] (1)
      1. RmlC-like cupins [51182] (1)
        1. Germin/Seed storage 7S protein [51187] (1)
          1. Seed storage 7S protein [51188]
            1. Jack bean (Canavalia ensiformis), canavalin/vinculin [TaxId: 3823] [51190] (1) picpic
  3. Alpha and beta proteins (a/b) [51349] (2)
    Mainly parallel beta sheets (beta-alpha-beta units)
    1. Flavodoxin-like [52171] (1)
      1. Class I glutamine amidotransferase-like [52317] (1)
        1. DJ-1/PfpI [52325] (1)
          1. Hypothetical protein YhbO [89601]
            1. Escherichia coli [TaxId: 562] [89602] (2) picpic
    2. Phosphorylase/hydrolase-like [53162] (1)
      1. Zn-dependent exopeptidases [53187] (1)
        1. Bacterial dinuclear zinc exopeptidases [53204] (1)
          1. IAA-amino acid hydrolase, catalytic domain [117663]
            1. Mouse-ear cress (Arabidopsis thaliana) [TaxId: 3702] [117664] (1) picpic
  4. Alpha and beta proteins (a+b) [53931] (3)
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
    1. CBS-domain [54630] (1)
      1. CBS-domain [54631] (1)
        1. CBS-domain [54632] (13)
          1. Hypothetical protein TM0935 [102895]
            1. Thermotoga maritima [TaxId: 2336] [102896] (2) picpic
          2. Hypothetical protein MTH1622 [102897]
            1. Archaeon Methanobacterium thermoautotrophicum [TaxId: 145262] [102898] (2) picpic
          3. Hypothetical protein Ta0289 [102899]
            1. Archaeon Thermoplasma acidophilum [TaxId: 2303] [102900] (4) picpic
          4. Type II inosine monophosphate dehydrogenase CBS domains [54633]
            1. Human (Homo sapiens), type I [TaxId: 9606] [89899] (4) picpic
            2. Human (Homo sapiens), type II [TaxId: 9606] [54634] (10) picpic
            3. Chinese hamster (Cricetulus griseus) [TaxId: 10029] [64260] (2) picpic
            4. Streptococcus pyogenes [TaxId: 1314] [54635] (2) picpic
          5. Hypothetical protein YkuL [117881]
            1. Bacillus subtilis [TaxId: 1423] [117882] (4) picpic
          6. Nuclear protein SNF4 [143134]
            1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [143135] (1) picpic
          7. Hypothetical protein TM0892, CBS tandem [143136]
            1. Thermotoga maritima [TaxId: 2336] [143137] (4) picpic
          8. Chloride channel protein, CBS tandem [143138]
            1. Marbled electric ray (Torpedo marmorata) [TaxId: 7788] [143139] (4) picpic
          9. Hypothetical protein VC0737 [143140]
            1. Vibrio cholerae [TaxId: 666] [143141] (4) picpic
          10. Hypothetical protein Rv2626c [143142]
            1. Mycobacterium tuberculosis [TaxId: 1773] [143143] (8) picpic
    2. Ferredoxin-like [54861] (1)
      1. Bacterial exopeptidase dimerisation domain [55031] (1)
        1. Bacterial exopeptidase dimerisation domain [55032] (1)
          1. IAA-amino acid hydrolase [117979]
            1. Mouse-ear cress (Arabidopsis thaliana) [TaxId: 3702] [117980] (1) picpic
    3. Homing endonuclease-like [55603] (1)
      1. Homing endonucleases [55608] (1)
        1. Group I mobile intron endonuclease [55609] (1)
          1. DNA endonuclease I-SceI [118055]
            1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [118056] (2) picpic
  5. Multi-domain proteins (alpha and beta) [56572] (0)
    Folds consisting of two or more domains belonging to different classes
  6. Membrane and cell surface proteins and peptides [56835] (1)
    Does not include proteins in the immune system
    1. Family A G protein-coupled receptor-like [81322] (1)
      1. Family A G protein-coupled receptor-like [81321] (1)
        1. Bacteriorhodopsin-like [81319] (1)
          1. Sensory rhodopsin II [64526]
            1. Archaeon Natronobacterium pharaonis [TaxId: 2257] [64527] (1) picpic
  7. Small proteins [56992] (1)
    Usually dominated by metal ligand, heme, and/or disulfide bridges
    1. C2H2 and C2HC zinc fingers [57666] (1)
      1. C2H2 and C2HC zinc fingers [57667] (1)
        1. Classic zinc finger, C2H2 [57668] (1)
          1. Zinc finger protein 593, ZNF593 [144151]
            1. Human (Homo sapiens) [TaxId: 9606] [144152] (1) picpic
  8. Coiled coil proteins [57942] (0)
    Not a true class
  9. Low resolution protein structures [58117] (1)
    Not a true class
    1. Proteins of incorrect, partial and unknown sequence [58207] (1)
      1. Proteins of incorrect, partial and unknown sequence [58208] (1)
        1. Proteins of incorrect, partial and unknown sequence [58209] (6)
          1. Lactate dehydrogenase [58210]
            1. Dogfish (Squalus acanthias) [TaxId: 7797] [58211] (1) picpic
          2. Glutathione reductase [58212]
            1. Human (Homo sapiens) [TaxId: 9606] [58213] (1) picpic
          3. KDPG aldolase [58216]
            1. Pseudomonas putida [TaxId: 303] [58217] (1) picpic
          4. Pyruvate kinase [58218]
            1. Cat (Felis catus) [TaxId: 9685] [58219] (1) picpic
          5. Phosphoglycerate kinase [58220]
            1. Horse (Equus caballus) [TaxId: 9796] [58221] (1) picpic
          6. Catalase [58222]
            1. Penicillium vitale [TaxId: 5079] [58223] (1) picpic
  10. Peptides [58231] (0)
    Peptides and fragments. Not a true class
  11. Designed proteins [58788] (0)
    Experimental structures of proteins with essentially non-natural sequences. Not a true class
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MRC site Generated from scop database 1.73_1.75 history with scopm 1.101 on Tue Jun 2 14:07:01 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk