Structural Classification of Proteins
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Changes in domain definitions and classification
Release 1.73 ---> 1.75

Root: scop

Classes:

  1. All alpha proteins [46456] (1)
    1. Globin-like [46457] (1)
      1. Globin-like [46458] (1)
        1. Globins [46463] (1)
          1. Hemoglobin, beta-chain [46500]
            1. Horse (Equus caballus) [TaxId: 9796] [46504] (1)
              1. 1s0h picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=158216,px=same
                1. region b:1-146 [118837] picpic
  2. All beta proteins [48724] (4)
    1. Immunoglobulin-like beta-sandwich [48725] (1)
      1. Purple acid phosphatase, N-terminal domain [49363] (1)
        1. Purple acid phosphatase, N-terminal domain [49364] (1)
          1. Purple acid phosphatase, N-terminal domain [49365]
            1. Sweet potato (Ipomoea batatas) [TaxId: 4120] [117063] (1)
              1. 1xzw picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144583
                1. region b:501-516 [116272] picpic
    2. Split barrel-like [50474] (1)
      1. FMN-binding split barrel [50475] (1)
        1. PNP-oxidase like [50476] (1)
          1. NimA-related protein DR0842 [117228]
            1. Deinococcus radiodurans [TaxId: 1299] [117229] (4)
              1. 1w3o picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144544
                1. chain a [114142] picpic
              2. 1w3p picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144545
                1. chain a [114143] picpic
              3. 1w3q picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144546
                1. chain a [114144] picpic
              4. 1w3r picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144547
                1. chain a [114145] picpic
    3. Trypsin-like serine proteases [50493] (1)
      1. Trypsin-like serine proteases [50494] (1)
        1. Viral proteases [50596] (1)
          1. NS3 protease [50600]
            1. Human hepatitis C virus (HCV), different isolates [TaxId: 11103] [50601] (2)
              1. 1rtl picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144371
                1. chain b [111935] picpic
              2. 1rtl picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144371
                1. chain d [111936] picpic
    4. Double-stranded beta-helix [51181] (1)
      1. RmlC-like cupins [51182] (1)
        1. Germin/Seed storage 7S protein [51187] (1)
          1. Seed storage 7S protein [51188]
            1. Jack bean (Canavalia ensiformis), canavalin/vinculin [TaxId: 3823] [51190] (1)
              1. 1dgr picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144355
                1. chain m,n [28101] picpic
  3. Alpha and beta proteins (a/b) [51349] (2)
    Mainly parallel beta sheets (beta-alpha-beta units)
    1. Flavodoxin-like [52171] (1)
      1. Class I glutamine amidotransferase-like [52317] (1)
        1. DJ-1/PfpI [52325] (1)
          1. Hypothetical protein YhbO [89601]
            1. Escherichia coli [TaxId: 562] [89602] (2)
              1. 1oi4 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144364
                1. chain a [87047] picpic
              2. 1oi4 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144365
                1. chain b [87048] picpic
    2. Phosphorylase/hydrolase-like [53162] (1)
      1. Zn-dependent exopeptidases [53187] (1)
        1. Bacterial dinuclear zinc exopeptidases [53204] (1)
          1. IAA-amino acid hydrolase, catalytic domain [117663]
            1. Mouse-ear cress (Arabidopsis thaliana) [TaxId: 3702] [117664] (1)
              1. 1xmb picpicxref
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                modified domain definition: A:16-194,A:314-407 -> A:37-215,A:335-428
                1. region a:16-194,a:314-407 [115479] picpic
  4. Alpha and beta proteins (a+b) [53931] (3)
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
    1. CBS-domain [54630] (1)
      1. CBS-domain [54631] (1)
        1. CBS-domain [54632] (13)
          1. Hypothetical protein TM0935 [102895]
            1. Thermotoga maritima [TaxId: 2336] [102896] (2)
              1. 1o50 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144363
                1. region a:-2-69 [92478] picpic
              2. 1o50 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144363
                1. region a:77-145 [92479] picpic
          2. Hypothetical protein MTH1622 [102897]
            1. Archaeon Methanobacterium thermoautotrophicum [TaxId: 145262] [102898] (2)
              1. 1pbj picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144366
                1. region a:2-60 [94414] picpic
              2. 1pbj picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144366
                1. region a:61-121 [94415] picpic
          3. Hypothetical protein Ta0289 [102899]
            1. Archaeon Thermoplasma acidophilum [TaxId: 2303] [102900] (4)
              1. 1pvm picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144367
                1. region a:1-64 [95171] picpic
              2. 1pvm picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144367
                1. region a:65-142 [95172] picpic
              3. 1pvm picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144368
                1. region b:-5-64 [95174] picpic
              4. 1pvm picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144368
                1. region b:65-142 [95175] picpic
          4. Type II inosine monophosphate dehydrogenase CBS domains [54633]
            1. Human (Homo sapiens), type I [TaxId: 9606] [89899] (4)
              1. 1jcn picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144356
                1. region a:112-164 [84161] picpic
              2. 1jcn picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144356
                1. region a:181-231 [84162] picpic
              3. 1jcn picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144357
                1. region b:112-164 [84164] picpic
              4. 1jcn picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144357
                1. region b:181-231 [84165] picpic
            2. Human (Homo sapiens), type II [TaxId: 9606] [54634] (10)
              1. 1b3o picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144354
                1. region b:112-159 [38538] picpic
              2. 1b3o picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144354
                1. region b:178-231 [38539] picpic
              3. 1nf7 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144359
                1. region a:112-166 [91853] picpic
              4. 1nf7 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144359
                1. region a:170-231 [91854] picpic
              5. 1nf7 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144360
                1. region b:112-166 [91856] picpic
              6. 1nf7 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144360
                1. region b:170-231 [91857] picpic
              7. 1nfb picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144361
                1. region a:112-152 [91859] picpic
              8. 1nfb picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144361
                1. region a:188-231 [91860] picpic
              9. 1nfb picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144362
                1. region b:112-152 [91862] picpic
              10. 1nfb picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144362
                1. region b:188-231 [91863] picpic
            3. Chinese hamster (Cricetulus griseus) [TaxId: 10029] [64260] (2)
              1. 1jr1 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144358
                1. region a:113-155 [63242] picpic
              2. 1jr1 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144358
                1. region a:178-232 [63243] picpic
            4. Streptococcus pyogenes [TaxId: 1314] [54635] (2)
              1. 1zfj picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144739
                1. region a:95-158 [38540] picpic
              2. 1zfj picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144739
                1. region a:159-220 [38541] picpic
          5. Hypothetical protein YkuL [117881]
            1. Bacillus subtilis [TaxId: 1423] [117882] (4)
              1. 1yav picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144629
                1. region a:13-75 [116595] picpic
              2. 1yav picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144629
                1. region a:76-144 [116596] picpic
              3. 1yav picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144630
                1. region b:13-75 [116597] picpic
              4. 1yav picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144630
                1. region b:76-144 [116598] picpic
          6. Nuclear protein SNF4 [143134]
            1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [143135] (1)
              1. 2nyc picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                modified domain definition: A:181-265 -> A:181-320
                1. region a:181-265 [138812] picpic
          7. Hypothetical protein TM0892, CBS tandem [143136]
            1. Thermotoga maritima [TaxId: 2336] [143137] (4)
              1. 1vr9 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144433
                1. region a:1-60 [120446] picpic
              2. 1vr9 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144433
                1. region a:61-121 [120447] picpic
              3. 1vr9 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144434
                1. region b:1-60 [120448] picpic
              4. 1vr9 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144434
                1. region b:61-121 [120449] picpic
          8. Chloride channel protein, CBS tandem [143138]
            1. Marbled electric ray (Torpedo marmorata) [TaxId: 7788] [143139] (4)
              1. 2d4z picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=145071
                1. region a:691-770 [131260] picpic
              2. 2d4z picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=145071
                1. region a:527-606 [131261] picpic
              3. 2d4z picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=145072
                1. region b:691-770 [131262] picpic
              4. 2d4z picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=145072
                1. region b:527-606 [131263] picpic
          9. Hypothetical protein VC0737 [143140]
            1. Vibrio cholerae [TaxId: 666] [143141] (4)
              1. 2o16 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=145710
                1. region a:20-82 [138869] picpic
              2. 2o16 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=145710
                1. region a:92-158 [138870] picpic
              3. 2o16 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=145711
                1. region b:20-80 [138871] picpic
              4. 2o16 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=145711
                1. region b:92-158 [138872] picpic
          10. Hypothetical protein Rv2626c [143142]
            1. Mycobacterium tuberculosis [TaxId: 1773] [143143] (8)
              1. 1xkf picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144578
                1. region a:2-68 [122077] picpic
              2. 1xkf picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144578
                1. region a:69-124 [122078] picpic
              3. 1xkf picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144579
                1. region b:2-68 [122079] picpic
              4. 1xkf picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144579
                1. region b:69-123 [122080] picpic
              5. 1y5h picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144595
                1. region a:69-124 [122635] picpic
              6. 1y5h picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144595
                1. region a:2-68 [122636] picpic
              7. 1y5h picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144596
                1. region b:69-123 [122637] picpic
              8. 1y5h picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=144596
                1. region b:2-68 [122638] picpic
    2. Ferredoxin-like [54861] (1)
      1. Bacterial exopeptidase dimerisation domain [55031] (1)
        1. Bacterial exopeptidase dimerisation domain [55032] (1)
          1. IAA-amino acid hydrolase [117979]
            1. Mouse-ear cress (Arabidopsis thaliana) [TaxId: 3702] [117980] (1)
              1. 1xmb picpicxref
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                modified domain definition: A:195-313 -> A:216-334
                1. region a:195-313 [115480] picpic
    3. Homing endonuclease-like [55603] (1)
      1. Homing endonucleases [55608] (1)
        1. Group I mobile intron endonuclease [55609] (1)
          1. DNA endonuclease I-SceI [118055]
            1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [118056] (2)
              1. 1r7m picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                modified domain definition: B:303-320 -> B:303-420
                1. region b:303-320 [111715] picpic
              2. 1r7m picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                modified domain definition: B:321-525 -> B:421-525
                1. region b:321-525 [111716] picpic
  5. Multi-domain proteins (alpha and beta) [56572] (0)
    Folds consisting of two or more domains belonging to different classes
  6. Membrane and cell surface proteins and peptides [56835] (1)
    Does not include proteins in the immune system
    1. Family A G protein-coupled receptor-like [81322] (1)
      1. Family A G protein-coupled receptor-like [81321] (1)
        1. Bacteriorhodopsin-like [81319] (1)
          1. Sensory rhodopsin II [64526]
            1. Archaeon Natronobacterium pharaonis [TaxId: 2257] [64527] (1)
              1. 1h2s picpic
                cl=same,cf=81334,sf=158212,fa=158213,dm=158214,sp=158215,px=same
                1. chain b [76579] picpic
  7. Small proteins [56992] (1)
    Usually dominated by metal ligand, heme, and/or disulfide bridges
    1. C2H2 and C2HC zinc fingers [57666] (1)
      1. C2H2 and C2HC zinc fingers [57667] (1)
        1. Classic zinc finger, C2H2 [57668] (1)
          1. Zinc finger protein 593, ZNF593 [144151]
            1. Human (Homo sapiens) [TaxId: 9606] [144152] (1)
              1. 1zr9 picpic
                cl=same,cf=same,sf=same,fa=111436,dm=same,sp=same,px=same
                1. region a:28-94 [125529] picpic
  8. Coiled coil proteins [57942] (0)
    Not a true class
  9. Low resolution protein structures [58117] (1)
    Not a true class
    1. Proteins of incorrect, partial and unknown sequence [58207] (1)
      1. Proteins of incorrect, partial and unknown sequence [58208] (1)
        1. Proteins of incorrect, partial and unknown sequence [58209] (6)
          1. Lactate dehydrogenase [58210]
            1. Dogfish (Squalus acanthias) [TaxId: 7797] [58211] (1)
              1. 3ldh picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
          2. Glutathione reductase [58212]
            1. Human (Homo sapiens) [TaxId: 9606] [58213] (1)
              1. 1grh picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
          3. KDPG aldolase [58216]
            1. Pseudomonas putida [TaxId: 303] [58217] (1)
              1. 1kga picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
          4. Pyruvate kinase [58218]
            1. Cat (Felis catus) [TaxId: 9685] [58219] (1)
              1. 1pyk picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
          5. Phosphoglycerate kinase [58220]
            1. Horse (Equus caballus) [TaxId: 9796] [58221] (1)
              1. 2pgk picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
          6. Catalase [58222]
            1. Penicillium vitale [TaxId: 5079] [58223] (1)
              1. 4cat picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
  10. Peptides [58231] (0)
    Peptides and fragments. Not a true class
  11. Designed proteins [58788] (0)
    Experimental structures of proteins with essentially non-natural sequences. Not a true class
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MRC site Generated from scop database 1.73_1.75 history with scopm 1.101 on Tue Jun 2 14:07:01 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk