Structural Classification of Proteins
Changes in domain definitions and classification
Release 1.71 ---> 1.73
Root: scop
Classes:
All alpha proteins
[46456] (82)
Globin-like
[46457] (1)
Long alpha-hairpin
[46556] (3)
LEM/SAP HeH motif
[63450] (1)
Cytochrome c
[46625] (1)
DNA/RNA-binding 3-helical bundle
[46688] (6)
Another 3-helical bundle
[81602] (1)
RuvA C-terminal domain-like
[46928] (2)
Putative DNA-binding domain
[46954] (1)
Spectrin repeat-like
[46965] (1)
immunoglobulin/albumin-binding domain-like
[46996] (1)
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
[47004] (1)
Protozoan pheromone-like
[47013] (1)
Acyl-CoA binding protein-like
[47026] (1)
alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
[47044] (1)
VHP, Villin headpiece domain
[47049] (1)
S15/NS1 RNA-binding domain
[47059] (1)
T4 endonuclease V
[47076] (1)
Fertilization protein
[47081] (1)
PGBD-like
[47089] (1)
HMG-box
[47094] (1)
Histone-fold
[47112] (1)
Four-helical up-and-down bundle
[47161] (6)
Ferritin-like
[47239] (1)
4-helical cytokines
[47265] (1)
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
[47322] (1)
Acyl carrier protein-like
[47335] (3)
ROP-like
[47379] (1)
lambda repressor-like DNA-binding domains
[47412] (1)
EF Hand-like
[47472] (2)
CH domain-like
[47575] (1)
Domain of poly(ADP-ribose) polymerase
[47586] (1)
Glutathione S-transferase (GST), C-terminal domain
[47615] (1)
Methionine synthase domain-like
[47643] (1)
Anaphylotoxins (complement system)
[47685] (1)
Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
[47698] (1)
p53 tetramerization domain
[47718] (1)
Domain of early E2A DNA-binding protein, ADDBP
[47723] (1)
Chemotaxis receptor methyltransferase CheR, N-terminal domain
[47756] (1)
SAM domain-like
[47768] (8)
Retroviral matrix proteins
[47835] (1)
Apolipophorin-III
[47856] (1)
Saposin-like
[47861] (1)
Annexin
[47873] (1)
Transducin (alpha subunit), insertion domain
[47894] (1)
N-terminal domain of the delta subunit of the F1F0-ATP synthase
[47927] (1)
Retrovirus capsid protein, N-terminal core domain
[47942] (1)
Cyclin-like
[47953] (1)
Ribosomal protein S7
[47972] (1)
DNA polymerase III clamp loader subunits, C-terminal domain
[48018] (1)
Iron-dependent repressor protein, dimerization domain
[47978] (1)
DEATH domain
[47985] (1)
Guanido kinase N-terminal domain
[48033] (1)
Hemocyanin, N-terminal domain
[48049] (1)
Di-copper centre-containing domain
[48055] (1)
Transcription factor STAT-4 N-domain
[48091] (1)
Heme-dependent peroxidases
[48112] (1)
DNA-glycosylase
[48149] (1)
An anticodon-binding domain of class I aminoacyl-tRNA synthetases
[48162] (1)
R1 subunit of ribonucleotide reductase, N-terminal domain
[48167] (1)
Cryptochrome/photolyase FAD-binding domain
[48172] (1)
6-phosphogluconate dehydrogenase C-terminal domain-like
[48178] (1)
Uteroglobin-like
[48200] (1)
alpha/alpha toroid
[48207] (2)
Citrate synthase
[48255] (1)
Cytochrome P450
[48263] (1)
Acid phosphatase/Vanadium-dependent haloperoxidase
[48316] (1)
H-NS histone-like proteins
[81274] (1)
Sigma2 domain of RNA polymerase sigma factors
[88945] (1)
GTPase activation domain, GAP
[48349] (1)
alpha-alpha superhelix
[48370] (4)
Lipoxigenase
[48483] (1)
Tetracyclin repressor-like, C-terminal domain
[48497] (1)
Nuclear receptor ligand-binding domain
[48507] (1)
Phospholipase C/P1 nuclease
[48536] (1)
Serum albumin-like
[48551] (1)
L-aspartase-like
[48556] (1)
Terpenoid synthases
[48575] (1)
GroEL equatorial domain-like
[48591] (1)
Cysteine alpha-hairpin motif
[47071] (1)
Phospholipase A2, PLA2
[48618] (1)
Fungal elicitin
[48646] (1)
Multiheme cytochromes
[48694] (1)
All beta proteins
[48724] (62)
Immunoglobulin-like beta-sandwich
[48725] (8)
Common fold of diphtheria toxin/transcription factors/cytochrome f
[49379] (5)
Prealbumin-like
[49451] (1)
alpha-Amylase inhibitor tendamistat
[49497] (1)
Cupredoxin-like
[49502] (1)
C2 domain-like
[49561] (3)
Nucleoplasmin-like/VP (viral coat and capsid proteins)
[88632] (2)
gamma-Crystallin-like
[49694] (1)
Lipase/lipooxygenase domain (PLAT/LH2 domain)
[49722] (1)
Heat shock protein 70kD (HSP70), peptide-binding domain
[100919] (1)
Ecotin, trypsin inhibitor
[49771] (1)
PEBP-like
[49776] (1)
Galactose-binding domain-like
[49784] (1)
ENV polyprotein, receptor-binding domain
[49829] (1)
Virus attachment protein globular domain
[49834] (1)
TNF-like
[49841] (1)
CUB-like
[49853] (1)
Osmotin, thaumatin-like protein
[49869] (1)
SMAD/FHA domain
[49878] (1)
Concanavalin A-like lectins/glucanases
[49898] (1)
Supersandwich
[49993] (1)
ISP domain
[50021] (1)
SH3-like barrel
[50036] (7)
GroES-like
[50128] (1)
PDZ domain-like
[50155] (1)
N-terminal domains of the minor coat protein g3p
[50175] (1)
Ribosomal protein L14
[50192] (1)
OB-fold
[50198] (5)
beta-Trefoil
[50352] (3)
Reductase/isomerase/elongation factor common domain
[50412] (2)
Elongation factor/aminomethyltransferase common domain
[50464] (1)
FMN-binding split barrel
[50474] (1)
Trypsin-like serine proteases
[50493] (1)
mu transposase, C-terminal domain
[50609] (1)
Domain of alpha and beta subunits of F1 ATP synthase-like
[50614] (1)
Acid proteases
[50629] (1)
ValRS/IleRS/LeuRS editing domain
[50676] (1)
Double psi beta-barrel
[50684] (2)
PH domain-like
[50728] (1)
Herpes virus serine proteinase, assemblin
[50788] (1)
PK beta-barrel domain-like
[50799] (1)
Lipocalins
[50813] (1)
Streptavidin-like
[50875] (1)
Cyclophilin-like
[50890] (1)
Oncogene products
[50903] (1)
4-bladed beta-propeller
[50922] (1)
6-bladed beta-propeller
[50938] (1)
7-bladed beta-propeller
[50964] (1)
Glycosyl hydrolase domain
[51010] (1)
WW domain-like
[51044] (1)
Carbonic anhydrase
[51068] (1)
Bacteriochlorophyll A protein
[51080] (1)
beta-Prism I
[51091] (1)
beta-Prism II
[51109] (1)
Single-stranded right-handed beta-helix
[51125] (2)
Single-stranded left-handed beta-helix
[51160] (1)
Double-stranded beta-helix
[51181] (4)
Barrel-sandwich hybrid
[51229] (3)
beta-clip
[51268] (4)
Hedgehog/intein (Hint) domain
[51293] (1)
Cyanovirin-N
[51321] (1)
Epsilon subunit of F1F0-ATP synthase N-terminal domain
[51343] (1)
Alpha and beta proteins (a/b)
[51349] (71)
Mainly parallel beta sheets (beta-alpha-beta units)
TIM beta/alpha-barrel
[51350] (16)
NAD(P)-binding Rossmann-fold domains
[51734] (1)
FAD/NAD(P)-binding domain
[51904] (1)
MurCD N-terminal domain
[51983] (1)
7-stranded beta/alpha barrel
[51988] (1)
PFL-like glycyl radical enzymes
[51997] (1)
The "swivelling" beta/beta/alpha domain
[52008] (3)
Barstar-like
[52037] (1)
Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)
[52046] (1)
SpoIIaa-like
[52086] (2)
ClpP/crotonase
[52095] (1)
DNA glycosylase
[52140] (1)
Aminoacid dehydrogenase-like, N-terminal domain
[53222] (1)
Flavodoxin-like
[52171] (6)
Ferredoxin reductase-like, C-terminal NADP-linked domain
[52342] (1)
Adenine nucleotide alpha hydrolase-like
[52373] (2)
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
[52417] (1)
Cryptochrome/photolyase, N-terminal domain
[52424] (1)
PIN domain-like
[88722] (1)
PreATP-grasp domain
[52439] (1)
DHS-like NAD/FAD-binding domain
[52466] (1)
Tubulin nucleotide-binding domain-like
[52489] (1)
HAD-like
[56783] (1)
Thiamin diphosphate-binding fold (THDP-binding)
[52517] (1)
P-loop containing nucleoside triphosphate hydrolases
[52539] (1)
PTS IIb component
[52727] (1)
Methylesterase CheB, C-terminal domain
[52737] (1)
Subtilisin-like
[52742] (1)
CoA-dependent acyltransferases
[52776] (1)
Phosphotyrosine protein phosphatases I-like
[52787] (2)
(Phosphotyrosine protein) phosphatases II
[52798] (1)
Rhodanese/Cell cycle control phosphatase
[52820] (1)
Thioredoxin fold
[52832] (1)
Pyruvate kinase C-terminal domain-like
[52934] (1)
Restriction endonuclease-like
[52979] (1)
Resolvase-like
[53040] (1)
IIA domain of mannose transporter, IIA-Man
[53061] (1)
Ribonuclease H-like motif
[53066] (4)
Phosphorylase/hydrolase-like
[53162] (3)
Macro domain-like
[52948] (1)
MurD-like peptide ligases, peptide-binding domain
[53243] (1)
Phosphoglycerate mutase-like
[53253] (1)
PRTase-like
[53270] (1)
vWA-like
[53299] (1)
FabD/lysophospholipase-like
[52150] (1)
Formyltransferase
[53327] (1)
S-adenosyl-L-methionine-dependent methyltransferases
[53334] (1)
PLP-dependent transferases
[53382] (1)
alpha/beta-Hydrolases
[53473] (1)
Dihydrofolate reductases
[53596] (1)
Ribokinase-like
[53612] (2)
Alkaline phosphatase-like
[53648] (1)
AraD-like aldolase/epimerase
[53638] (1)
Isocitrate/Isopropylmalate dehydrogenase-like
[53658] (1)
ATC-like
[53670] (1)
Tryptophan synthase beta subunit-like PLP-dependent enzymes
[53685] (1)
SIS domain
[53696] (1)
Formate dehydrogenase/DMSO reductase, domains 1-3
[53705] (1)
Aconitase iron-sulfur domain
[53731] (1)
Phosphoglycerate kinase
[53747] (1)
UDP-Glycosyltransferase/glycogen phosphorylase
[53755] (1)
Glutaminase/Asparaginase
[53773] (1)
Phosphofructokinase
[53783] (1)
Tetrapyrrole methylase
[53789] (1)
PEP carboxykinase-like
[53794] (1)
PEP carboxykinase N-terminal domain
[68922] (1)
Chelatase-like
[53799] (1)
Periplasmic binding protein-like I
[53821] (1)
Periplasmic binding protein-like II
[53849] (1)
Thiolase-like
[53900] (1)
Cytidine deaminase-like
[53926] (1)
Alpha and beta proteins (a+b)
[53931] (97)
Mainly antiparallel beta sheets (segregated alpha and beta regions)
Microbial ribonucleases
[53932] (1)
Lysozyme-like
[53954] (1)
Cysteine proteinases
[54000] (1)
RNase A-like
[54075] (1)
Prion-like
[54097] (1)
IL8-like
[54116] (1)
DNA-binding domain
[54170] (1)
Penicillin-binding protein 2x (pbp-2x), c-terminal domain
[54183] (1)
HIT-like
[54196] (1)
Ribosomal protein S5 domain 2-like
[54210] (1)
beta-Grasp (ubiquitin-like)
[54235] (7)
FAD-linked reductases, C-terminal domain
[54372] (1)
Cystatin-like
[54402] (3)
UBC-like
[54494] (1)
GFP-like
[54510] (1)
Pili subunits
[54522] (1)
FKBP-like
[54533] (2)
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
[54592] (1)
beta-hairpin-alpha-hairpin repeat
[74651] (1)
DNA-binding domain of Mlu1-box binding protein MBP1
[54615] (1)
CI-2 family of serine protease inhibitors
[54653] (1)
alpha/beta-Hammerhead
[54664] (1)
POZ domain
[54694] (1)
EF-Ts domain-like
[54712] (1)
ClpS-like
[54735] (1)
Anti-LPS factor/recA domain
[54751] (1)
Signal recognition particle alu RNA binding heterodimer, SRP9/14
[54761] (1)
dsRBD-like
[54767] (2)
Eukaryotic type KH-domain (KH-domain type I)
[54790] (1)
Nucleotidyltransferase
[81302] (1)
Enolase N-terminal domain-like
[54825] (1)
GroEL-intermediate domain like
[54848] (1)
Ferredoxin-like
[54861] (17)
eIF1-like
[55158] (1)
Hedgehog/DD-peptidase
[55165] (1)
IF3-like
[55199] (2)
Bacillus chorismate mutase-like
[55297] (1)
Tautomerase/MIF
[55330] (1)
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
[55346] (1)
Aha1/BPI domain-like
[55393] (1)
Subtilisin inhibitor
[55398] (1)
RNA bacteriophage capsid protein
[55404] (1)
Translation initiation factor eIF4e
[55417] (1)
CO dehydrogenase flavoprotein C-domain-like
[55423] (1)
Origin of replication-binding domain, RBD-like
[55463] (1)
FMN-dependent nitroreductase-like
[55468] (1)
Zincin-like
[55485] (2)
SH2-like
[55549] (1)
HPr-like
[55593] (1)
Homing endonuclease-like
[55603] (2)
T-fold
[55619] (1)
Cell cycle regulatory proteins
[55636] (1)
Ribosomal protein L9 C-domain
[55652] (1)
L9 N-domain-like
[55657] (1)
Regulatory factor Nef
[55670] (1)
CytB endotoxin-like
[55675] (1)
Class II aaRS and biotin synthetases
[55680] (1)
Acyl-CoA N-acyltransferases (Nat)
[55728] (1)
Gelsolin-like
[55752] (1)
Profilin-like
[55769] (2)
PR-1-like
[55796] (1)
Nudix
[55810] (1)
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
[55815] (1)
Thymidylate synthase/dCMP hydroxymethylase
[55830] (1)
N-acetylmuramoyl-L-alanine amidase-like
[55845] (1)
Cytochrome b5-like heme/steroid binding domain
[55855] (1)
DNA topoisomerase I domain
[55868] (1)
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
[55873] (1)
Pentein, beta/alpha-propeller
[55908] (1)
Creatinase/aminopeptidase
[55919] (1)
Glutamine synthetase/guanido kinase
[55930] (1)
TBP-like
[55944] (1)
S-adenosylmethionine synthetase
[55972] (1)
DNA clamp
[55978] (1)
Sulfite reductase hemoprotein (SiRHP), domains 2 and 4
[56013] (1)
Monooxygenase (hydroxylase) regulatory protein
[56028] (1)
ATP-grasp
[56058] (2)
SAICAR synthase-like
[56103] (1)
Protein kinase-like (PK-like)
[56111] (1)
FAD-binding domain
[56175] (1)
Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain
[56193] (1)
DNase I-like
[56218] (1)
Metallo-hydrolase/oxidoreductase
[56280] (1)
PP2C-like
[81607] (1)
Metallo-dependent phosphatases
[56299] (1)
LDH C-terminal domain-like
[56326] (1)
DNA breaking-rejoining enzymes
[56348] (1)
Ribosome inactivating proteins (RIP)
[56370] (1)
ADP-ribosylation
[56398] (1)
Peptide deformylase
[56419] (1)
C-type lectin-like
[56435] (1)
SRCR-like
[56486] (1)
Fibrinogen C-terminal domain-like
[56495] (1)
Methionine synthase activation domain-like
[56506] (1)
Nitric oxide (NO) synthase oxygenase domain
[56511] (1)
Penicillin binding protein dimerisation domain
[56518] (1)
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
[56533] (1)
Multi-domain proteins (alpha and beta)
[56572] (10)
Folds consisting of two or more domains belonging to different classes
Serpins
[56573] (1)
beta-lactamase/transpeptidase-like
[56600] (1)
Heme-dependent catalase-like
[56633] (1)
Carbohydrate phosphatase
[56654] (1)
DNA/RNA polymerases
[56671] (1)
Prokaryotic type I DNA topoisomerase
[56711] (1)
Type II DNA topoisomerase
[56718] (1)
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment
[56740] (1)
Acetyl-CoA synthetase-like
[56800] (1)
Ribosomal protein L1
[56807] (1)
Membrane and cell surface proteins and peptides
[56835] (8)
Does not include proteins in the immune system
Toxins' membrane translocation domains
[56836] (4)
Family A G protein-coupled receptor-like
[81322] (1)
Transmembrane helix hairpin
[81334] (1)
Transmembrane beta-barrels
[56924] (1)
Leukocidin-like
[56958] (1)
Perfringolysin
[56977] (1)
Viral glycoprotein, central and dimerisation domains
[56982] (1)
Anthrax protective antigen
[56987] (1)
Small proteins
[56992] (39)
Usually dominated by metal ligand, heme, and/or disulfide bridges
Insulin-like
[56993] (1)
Knottins (small inhibitors, toxins, lectins)
[57015] (12)
PMP inhibitors
[57282] (1)
Amb V allergen
[57295] (1)
Snake toxin-like
[57301] (1)
BPTI-like
[57361] (1)
Defensin-like
[57391] (1)
Hairpin loop containing domain-like
[57413] (1)
Neurotoxin III (ATX III)
[57418] (1)
LDL receptor-like module
[57423] (1)
Crambin-like
[57428] (1)
Kringle-like
[57439] (1)
Kazal-type serine protease inhibitors
[100894] (1)
Plant proteinase inhibitors
[100896] (1)
Trefoil/Plexin domain-like
[57491] (1)
Cystine-knot cytokines
[57500] (1)
Complement control module/SCR domain
[57534] (1)
Crisp domain-like
[57545] (1)
Blood coagulation inhibitor (disintegrin)
[57551] (1)
Serine protease inhibitors
[57566] (1)
TB module/8-cys domain
[57580] (1)
Heparin-binding domain from vascular endothelial growth factor
[57592] (1)
Antifungal protein (AGAFP)
[57597] (1)
FnI-like domain
[57602] (1)
GLA-domain
[57629] (1)
HIV-1 VPU cytoplasmic domain
[57646] (1)
HIPIP (high potential iron protein)
[57651] (1)
C2H2 and C2HC zinc fingers
[57666] (1)
Zn2/Cys6 DNA-binding domain
[57700] (1)
Glucocorticoid receptor-like (DNA-binding domain)
[57715] (1)
Retrovirus zinc finger-like domains
[57755] (1)
Rubredoxin-like
[57769] (5)
B-box zinc-binding domain
[57844] (1)
RING/U-box
[57849] (1)
Metallothionein
[57867] (1)
Ada DNA repair protein, N-terminal domain (N-Ada 10)
[57883] (1)
Cysteine-rich domain
[57888] (1)
Toxic hairpin
[57006] (2)
Zn-binding domains of ADDBP
[57916] (1)
Coiled coil proteins
[57942] (3)
Not a true class
Parallel coiled-coil
[57943] (4)
Stalk segment of viral fusion proteins
[58063] (1)
Antiparallel coiled-coil
[58086] (1)
Low resolution protein structures
[58117] (1)
Not a true class
Proteins of incorrect, partial and unknown sequence
[58207] (1)
Peptides
[58231] (44)
Peptides and fragments. Not a true class
Lantibiotic peptides
[58243] (1)
Leucocin-like bacteriocin
[100898] (1)
Antimicrobial beta-hairpin
[58251] (1)
Antimicrobial helix
[58268] (1)
Peptide hormones
[58283] (1)
delta toxin-like
[58307] (1)
Arg-rich RNA binding peptides
[58321] (1)
VPR protein fragments
[58353] (1)
Inactivation gate of potassium and sodium channels
[58358] (1)
Coagulation factor VIII, membrane-binding peptide
[58368] (1)
Phosphocholine cytidylyltransferase membrane-binding peptides
[58373] (1)
Parathyroid hormone fragments (residues between 1 and 39)
[58378] (1)
Liposaccharide-binding protein CAP18 (residues 106-137)
[58389] (1)
Polymorphic antigen SPAM-H1 (residues 90-127)
[58394] (1)
Insect toxins
[58399] (1)
Tertiapin
[58404] (1)
Pilin fragments
[58420] (1)
RP71935
[58427] (1)
Atrial natriuretic peptide
[58432] (1)
Compstatin
[58437] (1)
Endothelin-like
[58449] (1)
Heat-stable enterotoxin (HSE)
[58457] (1)
Conotoxins
[58464] (1)
Conantokin
[58494] (1)
Kappa-hefutoxin-like
[58507] (1)
Bradykinin
[58512] (1)
Transmembrane helical fragments
[58517] (1)
Topogenic peptides
[58555] (3)
Phospholamban fragments
[58568] (1)
Fragments of apolipoproteins
[58579] (1)
Transactivation protein TAT
[58593] (1)
Proline pipe
[58599] (1)
Amyloid peptides
[58604] (1)
Gelsolin fragment (residues 150-169)
[58609] (1)
Acetylcholine receptor fragment (residues alpha 67-76)
[58614] (1)
Thrombomodulin EGF domain fragment (residues 409-426)
[58619] (1)
Capsid protein major homology region peptide analog
[58629] (1)
CD4 and CD8 receptor regions
[58635] (1)
GroES fragments
[58645] (1)
cAMP and cGMP phosphodiesterase (PDE) fragments
[58650] (1)
HIV-1 Nef protein fragments
[58657] (1)
Transducin alpha-1 subunit rhodopsin binding domain (res. 340-350)
[58677] (1)
Human glutathione reductase (HGR) inhibitor
[58702] (1)
Small subunit C-terminal inhibitory peptide of ribonucleotide reductase
[58707] (1)
Designed proteins
[58788] (11)
Experimental structures of proteins with essentially non-natural sequences. Not a true class
Hybrid and chimeric proteins
[58789] (1)
Amphiphilic (amphipathic) alpha helix
[58798] (1)
Designed trimeric coiled-coil
[100903] (1)
Designed four-helix bundle protein
[58832] (1)
Peptide f (amphiphilic octadecapeptide)
[58846] (1)
Zinc finger design
[58856] (1)
Protein A Ig(Fc)-binding domain mimics
[58863] (1)
Zinc finger based beta-beta-alpha motif
[58868] (1)
helix-turn-helix motif
[58877] (1)
Right-handed coiled coil
[58887] (1)
Octreotide (Sandostatine), a somatostatine analogue
[58902] (1)
Enter
search
key:
Generated from scop database # 1.71_1.73 history with scopm 1.101 on Wed Nov 21 12:55:38 2007
Copyright
© 1994-2007 The scop authors / scop@mrc-lmb.cam.ac.uk