Root: scop

Classes:

1. All alpha proteins [46456] (82)
   1. Globin-like [46457] (1)
      1. Globin-like [46458] (1)
         1. Globins [46463] (16)
            1. Hemoglobin I [46464]
               1. Clam (Lucina pectinata) [46466] (4)
            2. Glycera globin [46467]
               1. Marine bloodworm (Glycera dibranchiata) [46468] (2)
            3. Myoglobin [46469]
               1. Sperm whale (Physeter catodon) [46470] (100)
               2. Sea hare (Aplysia limacina) [46471] (6)
               3. Common seal (Phoca vitulina) [46472] (1)
               4. Pig (Sus scrofa) [46473] (1)
               5. Horse (Equus caballus) [46474] (10)
               6. Human (Homo sapiens) [46475] (1)
               7. Asian elephant (Elephas maximus) [46476] (1)
               8. Loggerhead sea turtle (Caretta caretta) [46477] (2)
               9. Yellowfin tuna (Thunnus albacares) [46478] (1)
            4. Erythrocruorin [46479]
               1. Midge (Chironomus thummi thummi), fraction III [46480] (4)
            5. Leghemoglobin [46481]
               1. Yellow lupin (Lupinus luteus) [46482] (17)
            6. Lamprey globin [46518]
               1. Sea lamprey (Petromyzon marinus) [46519] (1)
            7. Ascaris hemoglobin, domain 1 [46520]
               1. Pig roundworm (Ascaris suum) [46521] (1)
            8. Hemoglobin, different isoforms [46524]
               1. Sea cucumber (Caudina (Molpadia) arenicola) [46525] (2)
   2. Long alpha-hairpin [46556] (3)
      1. GreA transcript cleavage protein, N-terminal domain [46557] (1)
         1. GreA transcript cleavage protein, N-terminal domain [46558] (1)
            1. GreA transcript cleavage protein, N-terminal domain [46559]
               1. Escherichia coli [46560] (1)
      2. Chaperone J-domain [46565] (1)
         1. Chaperone J-domain [46566] (2)
            1. HSP40 [46569]
               1. Human (Homo sapiens) [46570] (1)
            2. DnaJ chaperone, N-terminal (J) domain [46571]
               1. Escherichia coli [46572] (3)
      3. Epsilon subunit of F1F0-ATP synthase C-terminal domain [46604] (1)
         1. Epsilon subunit of F1F0-ATP synthase C-terminal domain [46605] (1)
            1. Epsilon subunit of F1F0-ATP synthase C-terminal domain [46606]
               1. Escherichia coli [46607] (1)
   3. LEM/SAP HeH motif [63450] (1)
      1. Rho termination factor, N-terminal domain [68912] (1)
         1. Rho termination factor, N-terminal domain [68913] (1)
            1. Rho termination factor, N-terminal domain [68914]
               1. Escherichia coli [50295] (2)
   4. Cytochrome c [46625] (1)
      1. Cytochrome c [46626] (1)
         1. monodomain cytochrome c [46627] (21)
            1. Cytochrome c6 (synonym: cytochrome c553) [46628]
               1. Monoraphidium braunii [46630] (3)
               2. Desulfovibrio vulgaris, different strains [46631] (2)
               3. Desulfovibrio desulfuricans [46632] (1)
               4. Chlamydomonas reinhardtii [46633] (2)
               5. Cyanobacterium (Synechococcus elongatus) [46634] (1)
            2. Cytochrome c552 [46636]
               1. Thermus thermophilus [46637] (1)
               2. Hydrogenobacter thermophilus [46640] (1)
               3. Nitrosomonas europaea [46641] (2)
            3. Mitochondrial cytochrome c [46642]
               1. Baker's yeast (Saccharomyces cerevisiae) [46643] (29)
               2. Horse (Equus caballus) [46644] (6)
               3. Rice embryos (Oryza sativa) [46645] (1)
               4. Bonito (Katsuwonus pelamis) [46647] (1)
            4. Cytochrome c2 [46650]
               1. Rhodospirillum rubrum [46651] (2)
               2. Rhodobacter capsulatus [46652] (1)
               3. Rhodobacter sphaeroides [46653] (2)
               4. Rhodopseudomonas viridis [46654] (1)
               5. Paracoccus denitrificans [46657] (2)
            5. Cytochrome c5 [46658]
               1. Azotobacter vinelandii [46659] (1)
            6. Cytochrome c551 [46660]
               1. Pseudomonas stutzeri [46661] (2)
               2. Pseudomonas aeruginosa [46662] (3)
               3. Ectothiorhodospira halophila [46664] (1)
   5. DNA/RNA-binding 3-helical bundle [46688] (6)
      1. Homeodomain-like [46689] (5)
         1. Homeodomain [46690] (10)
            1. Engrailed Homeodomain [46691]
               1. Drosophila melanogaster [46692] (1)
            2. Hepatocyte nuclear factor 1a (LFB1/HNF1) [46697]
               1. Rat (Rattus rattus) [46698] (2)
            3. Oct-1 POU Homeodomain [46699]
               1. Human (Homo sapiens) [46700] (1)
            4. Thyroid transcription factor 1 homeodomain [46703]
               1. Rat (Rattus norvegicus) [46704] (1)
            5. Oct-2 POU Homeodomain [46705]
               1. Human (Homo sapiens) [46706] (1)
            6. Oct-3 POU Homeodomain [46707]
               1. Mouse (Mus musculus) [46708] (1)
            7. Insulin gene enhancer protein isl-1 [46714]
               1. Rat (Rattus norvegicus) [46715] (1)
            8. Antennapedia Homeodomain [46716]
               1. Drosophila melanogaster [46717] (3)
            9. Fushi Tarazu protein [46722]
               1. Fruit fly (Drosophila melanogaster) [46723] (1)
            10. VND/NK-2 protein [46724]
                1. Fruit fly (Drosophila melanogaster) [46725] (1)
         2. Recombinase DNA-binding domain [46728] (3)
            1. gamma,delta resolvase (C-terminal domain) [46731]
               1. Escherichia coli [46732] (2)
            2. Ibeta subdomain of the mu end DNA-binding domain of phage mu transposase [46735]
               1. Bacteriophage mu [46736] (2)
            3. Transposase [46737]
               1. Bacteriophage mu [46738] (2)
         3. Myb/SANT domain [46739] (2)
            1. c-Myb, DNA-binding domain [46740]
               1. Mouse (Mus musculus) [46742] (8)
            2. b-Myb DNA binding domain [46743]
               1. Chicken (Gallus gallus) [46744] (2)
         4. DNA-binding domain of telomeric protein [46745] (1)
            1. DNA-binding domain of human telomeric protein, hTRF1 [46746]
               1. Human (Homo sapiens) [46747] (1)
         5. Tetracyclin repressor-like, N-terminal domain [46764] (1)
            1. Tetracyclin repressor (Tet-repressor, TetR) [46765]
               1. Escherichia coli [46766] (6)
      2. Methylated DNA-protein cysteine methyltransferase, C-terminal domain [46767] (1)
         1. Methylated DNA-protein cysteine methyltransferase, C-terminal domain [46768] (1)
            1. Ada DNA repair protein [46769]
               1. Escherichia coli [46770] (1)
      3. "Winged helix" DNA-binding domain [46785] (11)
         1. Biotin repressor-like [46786] (1)
            1. Biotin repressor, N-terminal domain [46787]
               1. Escherichia coli [46788] (2)
         2. LexA repressor, N-terminal DNA-binding domain [46789] (1)
            1. LexA repressor, N-terminal DNA-binding domain [46790]
               1. Escherichia coli [46791] (2)
         3. Arginine repressor (ArgR), N-terminal DNA-binding domain [46792] (1)
            1. Arginine repressor (ArgR), N-terminal DNA-binding domain [46793]
               1. Escherichia coli [46794] (1)
         4. Plant O-methyltransferase, N-terminal domain [63475] (1)
            1. Carminomycin 4-O-methyltransferase [109667]
               1. Streptomyces peucetius [109668] (4)
         5. Linker histone H1/H5 [46827] (1)
            1. Histone H1, globular domain [46830]
               1. Chicken (Gallus gallus) [46831] (1)
         6. Forkhead DNA-binding domain [46832] (1)
            1. Genesis [46837]
               1. Rat (Rattus norvegicus) [46838] (1)
         7. DNA-binding domain from rap30 [46841] (1)
            1. DNA-binding domain from rap30 [46842]
               1. Human (Homo sapiens) [46843] (2)
         8. Heat-shock transcription factor [46873] (2)
            1. Heat-shock transcription factor [46874]
               1. Drosophila melanogaster [46875] (2)
               2. Milk yeast (Kluyveromyces lactis) [46876] (2)
         9. Interferon regulatory factor [46877] (1)
            1. Interferon regulatory factor-2, IRF-2 [46880]
               1. Mouse (Mus musculus) [46881] (2)
         10. Iron-dependent repressor protein [46882] (1)
             1. Diphtheria toxin repressor (DtxR) [46883]
                1. Corynebacterium diphtheriae [46884] (4)
         11. Methionine aminopeptidase, insert domain [46887] (2)
             1. Methionine aminopeptidase, insert domain [46888]
                1. Archaeon Pyrococcus furiosus [46889] (1)
                2. Human (Homo sapiens) [46890] (3)
      4. C-terminal effector domain of the bipartite response regulators [46894] (2)
         1. PhoB-like [46895] (1)
            1. OmpR [46896]
               1. Escherichia coli [46897] (2)
         2. GerE-like (LuxR/UhpA family of transcriptional regulators) [46900] (1)
            1. Nitrate/nitrite response regulator (NarL) [46901]
               1. Escherichia coli [46902] (1)
      5. TrpR-like [48295] (1)
         1. Trp repressor, TrpR [48296] (1)
            1. Trp repressor, TrpR [48297]
               1. Escherichia coli [48298] (1)
      6. Ribosomal protein L11, C-terminal domain [46906] (1)
         1. Ribosomal protein L11, C-terminal domain [46907] (1)
            1. Ribosomal protein L11, C-terminal domain [46908]
               1. Bacillus stearothermophilus [46909] (5)
   6. Another 3-helical bundle [81602] (1)
      1. Protein serine/threonine phosphatase 2C, C-terminal domain [81601] (1)
         1. Protein serine/threonine phosphatase 2C, C-terminal domain [81600] (1)
            1. Protein serine/threonine phosphatase 2C, C-terminal domain [81599]
               1. Human (Homo sapiens) [81598] (1)
   7. RuvA C-terminal domain-like [46928] (2)
      1. DNA helicase RuvA subunit, C-terminal domain [46929] (1)
         1. DNA helicase RuvA subunit, C-terminal domain [46930] (1)
            1. DNA helicase RuvA subunit, C-terminal domain [46931]
               1. Escherichia coli [46932] (2)
      2. CRAL/TRIO N-terminal domain [46938] (1)
         1. CRAL/TRIO N-terminal domain [46939] (1)
            1. N-terminal domain of phosphatidylinositol transfer protein sec14p [46940]
               1. Baker's yeast (Saccharomyces cerevisiae) [46941] (1)
   8. Putative DNA-binding domain [46954] (1)
      1. Putative DNA-binding domain [46955] (2)
         1. DNA repair factor XPA DNA- and RPA-binding domain, C-terminal subdomain [46959] (1)
            1. DNA repair factor XPA DNA- and RPA-binding domain, C-terminal subdomain [46960]
               1. Human (Homo sapiens) [46961] (1)
         2. Excisionase-like [46891] (1)
            1. mu transposase, DNA-binding domain [46892]
               1. Bacteriophage mu [46893] (2)
   9. Spectrin repeat-like [46965] (1)
      1. Spectrin repeat [46966] (1)
         1. Spectrin repeat [46967] (1)
            1. Spectrin alpha chain [46968]
               1. Chicken (Gallus gallus) [46970] (1)
   10. immunoglobulin/albumin-binding domain-like [46996] (1)
       1. Bacterial immunoglobulin/albumin-binding domains [46997] (2)
          1. Immunoglobulin-binding protein A modules [46998] (1)
             1. Immunoglobulin-binding protein A modules [46999]
                1. Staphylococcus aureus [47000] (6)
          2. GA module, an albumin-binding domain [47001] (1)
             1. PAB [47002]
                1. Peptostreptococcus magnus [47003] (2)
   11. Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex [47004] (1)
       1. Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex [47005] (1)
          1. Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex [47006] (2)
             1. E3-binding domain of dihydrolipoamide succinyltransferase [47009]
                1. Escherichia coli [47010] (2)
             2. E3/E1 binding domain of dihydrolipoyl acetyltransferase [47011]
                1. Bacillus stearothermophilus [47012] (2)
   12. Protozoan pheromone-like [47013] (1)
       1. Protozoan pheromone proteins [47014] (1)
          1. Protozoan pheromone proteins [47015] (4)
             1. ER-1 [47016]
                1. Euplotes raikovi [47017] (2)
             2. ER-2 [47018]
                1. Euplotes raikovi [47019] (1)
             3. ER-10 [47020]
                1. Euplotes raikovi [47021] (1)
             4. ER-11 [47022]
                1. Euplotes raikovi [47023] (1)
   13. Acyl-CoA binding protein-like [47026] (1)
       1. Acyl-CoA binding protein [47027] (1)
          1. Acyl-CoA binding protein [47028] (1)
             1. Acyl-CoA binding protein [47029]
                1. Cow (Bos taurus) [47030] (2)
   14. alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 [47044] (1)
       1. alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 [47045] (1)
          1. alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 [47046] (1)
             1. alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 [47047]
                1. Human (Homo sapiens) [47048] (2)
   15. VHP, Villin headpiece domain [47049] (1)
       1. VHP, Villin headpiece domain [47050] (1)
          1. VHP, Villin headpiece domain [47051] (1)
             1. Villin [47052]
                1. Chicken (Gallus gallus) [47053] (1)
   16. S15/NS1 RNA-binding domain [47059] (1)
       1. S15/NS1 RNA-binding domain [47060] (2)
          1. N-terminal, RNA-binding domain of nonstructural protein NS1 [47061] (1)
             1. N-terminal, RNA-binding domain of nonstructural protein NS1 [47062]
                1. Influenza A virus [47063] (1)
          2. Ribosomal protein S15 [47064] (2)
             1. Ribosomal protein S15 [47065]
                1. Bacillus stearothermophilus [47066] (1)
                2. Thermus thermophilus [47067] (1)
   17. T4 endonuclease V [47076] (1)
       1. T4 endonuclease V [47077] (1)
          1. T4 endonuclease V [47078] (1)
             1. T4 endonuclease V [47079]
                1. Bacteriophage T4 [47080] (4)
   18. Fertilization protein [47081] (1)
       1. Fertilization protein [47082] (1)
          1. Fertilization protein [47083] (1)
             1. Lysin [47084]
                1. Red abalone (Haliotis rufescens) [47085] (1)
   19. PGBD-like [47089] (1)
       1. PGBD-like [47090] (2)
          1. Peptidoglycan binding domain, PGBD [47091] (1)
             1. Zn2+ DD-carboxypeptidase, N-terminal domain [47092]
                1. Streptomyces albus G [47093] (1)
          2. MMP N-terminal domain [63427] (1)
             1. Stromelysin-1 (MMP-3) [63429]
                1. Human (Homo sapiens), fibroblast [63431] (1)
   20. HMG-box [47094] (1)
       1. HMG-box [47095] (1)
          1. HMG-box [47096] (3)
             1. High mobility group protein 1, HMG1 [47097]
                1. Rat (Rattus norvegicus) [47098] (3)
                2. Hamster (Cricetulus griseus) [47099] (4)
             2. HMG-D [47100]
                1. Drosophila melanogaster [47101] (1)
   21. Histone-fold [47112] (1)
       1. Histone-fold [47113] (1)
          1. Archaeal histone [47129] (2)
             1. Archaeal histone [68897]
                1. Archaeon Methanothermus fervidus, histone A [68895] (1)
                2. Archaeon Methanothermus fervidus, histone B [68896] (1)
   22. Four-helical up-and-down bundle [47161] (6)
       1. Apolipoprotein [47162] (1)
          1. Apolipoprotein [47163] (3)
             1. Apolipoprotein E [88703]
                1. Human (Homo sapiens), E3 [47165] (2)
                2. Human (Homo sapiens), E2 [47167] (2)
                3. Human (Homo sapiens), E4 [47169] (1)
       2. Aspartate receptor, ligand-binding domain [47170] (1)
          1. Aspartate receptor, ligand-binding domain [47171] (2)
             1. Aspartate receptor, ligand-binding domain [47172]
                1. Escherichia coli [47173] (1)
                2. Salmonella typhimurium [47174] (3)
       3. Cytochromes [47175] (2)
          1. Cytochrome b562 [47176] (1)
             1. Cytochrome b562 [47177]
                1. Escherichia coli [47178] (1)
          2. Cytochrome c'-like [47179] (3)
             1. Cytochrome c' [47180]
                1. Alcaligenes denitrificans [47183] (1)
                2. Alcaligenes sp. [47184] (1)
                3. Rhodobacter capsulatus [47186] (2)
       4. Hemerythrin [47188] (1)
          1. Hemerythrin [47189] (2)
             1. Hemerythrin [47190]
                1. Phascolopsis gouldii [47192] (1)
             2. Myohemerythin [47193]
                1. Sipunculan worm (Themiste zostericola) [47194] (3)
       5. Histidine-containing phosphotransfer domain, HPT domain [47226] (1)
          1. Aerobic respiration control sensor protein, ArcB [47227] (1)
             1. Aerobic respiration control sensor protein, ArcB [47228]
                1. Escherichia coli [47229] (2)
       6. Domain of the SRP/SRP receptor G-proteins [47364] (1)
          1. Domain of the SRP/SRP receptor G-proteins [47365] (2)
             1. Signal sequence recognition protein Ffh [47366]
                1. Thermus aquaticus [47367] (3)
             2. Signal recognition particle receptor, FtsY [47368]
                1. Escherichia coli [47369] (1)
   23. Ferritin-like [47239] (1)
       1. Ferritin-like [47240] (2)
          1. Ferritin [47241] (4)
             1. Rubrerythrin, N-terminal domain [47242]
                1. Desulfovibrio vulgaris [47243] (1)
             2. (Apo)ferritin [47246]
                1. Human (Homo sapiens), H chain [47247] (2)
                2. Horse (Equus caballus), L chain [47248] (4)
                3. Bullfrog (Rana catesbeiana) [47249] (6)
          2. Ribonucleotide reductase-like [47253] (1)
             1. Ribonucleotide reductase R2 [47257]
                1. Mouse (Mus musculus) [47260] (1)
   24. 4-helical cytokines [47265] (1)
       1. 4-helical cytokines [47266] (3)
          1. Long-chain cytokines [47267] (7)
             1. Granulocyte-colony stimulating factor (G-CSF) [47268]
                1. Human (Homo sapiens) [47269] (1)
                2. Cow (Bos taurus) [47270] (1)
                3. Dog (Canis familiaris) [47271] (1)
             2. Interleukin-6 [47272]
                1. Human (Homo sapiens) [47273] (3)
             3. Leukemia inhibitory factor (LIF) [47274]
                1. Mouse (Mus musculus) [47275] (2)
             4. Growth hormone, somatotropin [47276]
                1. Human (Homo sapiens) [47277] (2)
             5. Leptin (obesity protein) [47282]
                1. Human (Homo sapiens) [47283] (1)
          2. Short-chain cytokines [47286] (3)
             1. Interleukin-4 (IL-4) [47291]
                1. Human (Homo sapiens) [47292] (11)
             2. Interleukin-2 (IL-2) [47301]
                1. Human (Homo sapiens) [47302] (1)
             3. Interleukin-3 (IL-3) [47303]
                1. Human (Homo sapiens) [47304] (1)
          3. Interferons/interleukin-10 (IL-10) [47305] (6)
             1. Interleukin-10 (cytokine synthesis inhibitory factor, CSIF) [47306]
                1. Human (Homo sapiens) [47307] (3)
                2. Epstein-Barr virus [47308] (1)
             2. Interferon-beta [47309]
                1. Mouse (Mus musculus) [47311] (1)
             3. Interferon-alpha 2a [47314]
                1. Human (Homo sapiens) [47315] (1)
             4. Interferon-tau [47316]
                1. Sheep (Ovis aries) [47317] (1)
             5. Interferon-gamma [47318]
                1. Rabbit (Oryctolagus cuniculus) [47321] (1)
   25. Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47322] (1)
       1. Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47323] (1)
          1. Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47324] (2)
             1. Methionyl-tRNA synthetase (MetRS) [47325]
                1. Thermus thermophilus [47326] (1)
             2. Isoleucyl-tRNA synthetase (IleRS) [47328]
                1. Thermus thermophilus [47329] (1)
   26. Acyl carrier protein-like [47335] (3)
       1. ACP-like [47336] (1)
          1. Acyl-carrier protein (ACP) [47337] (2)
             1. Acyl carrier protein [47338]
                1. Escherichia coli [47339] (1)
             2. Actinorhodin polyketide synthase acyl carrier protein, ACT ACP [47340]
                1. Streptomyces coelicolor, A3(2) [47341] (2)
       2. Colicin E immunity proteins [47345] (1)
          1. Colicin E immunity proteins [47346] (2)
             1. ImmE7 protein (Im7) [47347]
                1. Escherichia coli [47348] (2)
             2. ImmE9 protein (Im9) [47351]
                1. Escherichia coli [47352] (2)
       3. Retrovirus capsid protein C-terminal domain [47353] (1)
          1. Retrovirus capsid protein C-terminal domain [47354] (2)
             1. EIAV capsid protein p26 [47355]
                1. Equine infectious anemia virus [47356] (1)
             2. HIV capsid protein, dimerisation domain [47359]
                1. Human immunodeficiency virus type 1 [47360] (4)
   27. ROP-like [47379] (1)
       1. ROP protein [47380] (1)
          1. ROP protein [47381] (1)
             1. ROP protein [47382]
                1. Escherichia coli [47383] (3)
   28. lambda repressor-like DNA-binding domains [47412] (1)
       1. lambda repressor-like DNA-binding domains [47413] (3)
          1. POU-specific domain [47414] (1)
             1. Oct-1 [47415]
                1. Human (Homo sapiens) [47416] (1)
          2. Phage repressors [47419] (6)
             1. lambda C1 repressor, DNA-binding domain [47420]
                1. Bacteriophage lambda [47421] (1)
             2. 434 C1 repressor, DNA-binding domain [47422]
                1. Bacteriophage 434 [47423] (4)
             3. cro 434 [47424]
                1. Bacteriophage 434 [47425] (2)
             4. P22 C2 repressor, DNA-binding domain [47426]
                1. Salmonella bacteriophage P22 [47427] (1)
             5. cro lambda repressor [47428]
                1. Bacteriophage lambda [47429] (2)
             6. Ner [47430]
                1. Bacteriophage mu [47431] (2)
          3. GalR/LacI-like bacterial regulator [47438] (3)
             1. Purine repressor (PurR), N-terminal domain [47439]
                1. Escherichia coli [47440] (2)
             2. Lac repressor (LacR), N-terminal domain [47441]
                1. Escherichia coli [47442] (1)
             3. Fructose repressor (FruR), N-terminal domain [47443]
                1. Escherichia coli [47444] (2)
   29. EF Hand-like [47472] (2)
       1. EF-hand [47473] (6)
          1. Calbindin D9K [47474] (2)
             1. Calbindin D9K [47475]
                1. Cow (Bos taurus) [47476] (8)
                2. Pig (Sus scrofa) [47477] (1)
          2. S100 proteins [47478] (2)
             1. Calcyclin (S100) [47479]
                1. Cow (Bos taurus), s100b [47482] (1)
                2. Human (Homo sapiens), psoriasin s100a7 [47485] (1)
          3. Osteonectin [47489] (1)
             1. C-terminal (EC) domain of BM-40/SPARC/osteonectin [47490]
                1. Human (Homo sapiens) [47491] (1)
          4. Parvalbumin [47492] (5)
             1. Oncomodulin [47493]
                1. Rat (Rattus norvegicus) [47494] (2)
             2. Parvalbumin [47495]
                1. Carp (Cyprinus carpio) [47496] (3)
                2. Pike (Esox lucius) [47497] (7)
                3. Leopard shark (Triakis semifasciata) [47498] (1)
                4. Silver hake (Merluccius bilinearis) [47500] (1)
          5. Calmodulin-like [47502] (13)
             1. Troponin C [47503]
                1. Chicken (Gallus gallus) [47504] (16)
                2. Turkey (Meleagris gallopavo) [47505] (2)
                3. Rabbit (Oryctolagus cuniculus) [47506] (3)
                4. Human (Homo sapiens), cardiac isoform [47508] (2)
             2. Sarcoplasmic calcium-binding protein [47509]
                1. Amphioxus (Branchiostoma lanceolatum) [47511] (1)
             3. Calmodulin [47516]
                1. Human (Homo sapiens) [47517] (2)
                2. Cow (Bos taurus) [47518] (6)
                3. Rat (Rattus rattus) [47519] (1)
                4. Chicken (Gallus gallus) [47520] (1)
                5. African frog (Xenopus laevis) [47521] (4)
                6. Drosophila melanogaster [47522] (1)
                7. Ciliate (Paramecium tetraurelia) [47523] (2)
             4. Recoverin [47533]
                1. Cow (Bos taurus) [47534] (3)
          6. Eps15 homology domain (EH domain) [47543] (1)
             1. Eps15 [47544]
                1. Human (Homo sapiens) [47546] (1)
       2. Cloroperoxidase [47571] (1)
          1. Cloroperoxidase [47572] (1)
             1. Cloroperoxidase [47573]
                1. Fungus (Caldariomyces fumago) [47574] (4)
   30. CH domain-like [47575] (1)
       1. Calponin-homology domain, CH-domain [47576] (1)
          1. Calponin-homology domain, CH-domain [47577] (2)
             1. beta-spectrin [47578]
                1. Human (Homo sapiens) [47579] (1)
             2. Fimbrin (Plastin), actin-crosslinking domain [47580]
                1. Human (Homo sapiens) [47581] (2)
   31. Domain of poly(ADP-ribose) polymerase [47586] (1)
       1. Domain of poly(ADP-ribose) polymerase [47587] (1)
          1. Domain of poly(ADP-ribose) polymerase [47588] (1)
             1. Domain of poly(ADP-ribose) polymerase [47589]
                1. Chicken (Gallus gallus) [47590] (6)
   32. Glutathione S-transferase (GST), C-terminal domain [47615] (1)
       1. Glutathione S-transferase (GST), C-terminal domain [47616] (1)
          1. Glutathione S-transferase (GST), C-terminal domain [47617] (6)
             1. Class mu GST [81348]
                1. Human (Homo sapiens) [47622] (1)
             2. Class alpha GST [81349]
                1. Schistosoma japonicum [47633] (4)
                2. Fasciola hepatica [47634] (1)
             3. Class sigma GST [81351]
                1. Squid (Ommastrephes sloani pacificus) [47631] (2)
             4. Class phi GST [81356]
                1. Maize (Zea mays), type III [47637] (1)
             5. Class beta GST [81357]
                1. Proteus mirabilis [47639] (1)
   33. Methionine synthase domain-like [47643] (1)
       1. Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain [47648] (1)
          1. Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain [47649] (1)
             1. Thymidine phosphorylase [47650]
                1. Escherichia coli [47651] (3)
   34. Anaphylotoxins (complement system) [47685] (1)
       1. Anaphylotoxins (complement system) [47686] (1)
          1. Anaphylotoxins (complement system) [47687] (2)
             1. C5a anaphylotoxin [47688]
                1. Human (Homo sapiens) [47689] (1)
                2. Pig (Sus scrofa domestica) [47690] (1)
   35. Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [47698] (1)
       1. Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [47699] (2)
          1. Plant lipid-transfer and hydrophobic proteins [47700] (4)
             1. Soybean hydrophobic protein [47701]
                1. Soybean (Glycine max) [47702] (1)
             2. Plant non-specific lipid-transfer protein (ns-LTP, ns-LTP1) [47703]
                1. Barley (Hordeum vulgare) [47705] (3)
                2. Maize (Zea mays) [47706] (3)
                3. Rice (Oryza sativa) [47707] (2)
          2. Proteinase/alpha-amylase inhibitors [47708] (2)
             1. Trypsin/alpha-amylase inhibitor RBI [47711]
                1. Ragi (Elucine coracana gaertneri), seeds [47712] (1)
             2. Hageman factor/amylase inhibitor [47713]
                1. Maize (Zea mays) [47714] (2)
   36. p53 tetramerization domain [47718] (1)
       1. p53 tetramerization domain [47719] (1)
          1. p53 tetramerization domain [47720] (1)
             1. p53 tetramerization domain [47721]
                1. Human (Homo sapiens) [47722] (1)
   37. Domain of early E2A DNA-binding protein, ADDBP [47723] (1)
       1. Domain of early E2A DNA-binding protein, ADDBP [47724] (1)
          1. Domain of early E2A DNA-binding protein, ADDBP [47725] (1)
             1. Domain of early E2A DNA-binding protein, ADDBP [47726]
                1. Human adenovirus type 5 [47727] (2)
   38. Chemotaxis receptor methyltransferase CheR, N-terminal domain [47756] (1)
       1. Chemotaxis receptor methyltransferase CheR, N-terminal domain [47757] (1)
          1. Chemotaxis receptor methyltransferase CheR, N-terminal domain [47758] (1)
             1. Chemotaxis receptor methyltransferase CheR, N-terminal domain [47759]
                1. Salmonella typhimurium [47760] (1)
   39. SAM domain-like [47768] (8)
       1. SAM/Pointed domain [47769] (2)
          1. Pointed domain [47770] (1)
             1. Ets-1 transcription factor pointed domain [47771]
                1. Mouse (Mus musculus) [47772] (1)
          2. SAM (sterile alpha motif) domain [47773] (1)
             1. EphB2 receptor [47776]
                1. Chicken (Gallus gallus) [47778] (1)
       2. RuvA domain 2-like [47781] (1)
          1. DNA helicase RuvA subunit, middle domain [47782] (1)
             1. DNA helicase RuvA subunit, middle domain [47783]
                1. Escherichia coli [47784] (2)
       3. C-terminal domain of RNA polymerase alpha subunit [47789] (1)
          1. C-terminal domain of RNA polymerase alpha subunit [47790] (1)
             1. C-terminal domain of RNA polymerase alpha subunit [47791]
                1. Escherichia coli [47792] (1)
       4. DNA polymerase beta, N-terminal domain-like [47802] (1)
          1. DNA polymerase beta, N-terminal domain-like [47803] (1)
             1. DNA polymerase beta, N-terminal (8 kD)-domain [47804]
                1. Rat (Rattus norvegicus) [47806] (4)
       5. DNA polymerase beta-like, second domain [81585] (1)
          1. DNA polymerase beta-like, second domain [81584] (1)
             1. DNA polymerase beta [81579]
                1. Rat (Rattus norvegicus) [81577] (12)
       6. 5' to 3' exonuclease, C-terminal subdomain [47807] (1)
          1. 5' to 3' exonuclease, C-terminal subdomain [47808] (3)
             1. T4 RNase H [47809]
                1. Bacteriophage T4 [47810] (1)
             2. 5' to 3' exonuclease domain of DNA polymerase Taq [47811]
                1. Thermus aquaticus [47812] (1)
             3. Flap endonuclease-1 (Fen-1 nuclease) [47815]
                1. Archaeon Methanococcus jannaschii [47816] (2)
       7. lambda integrase-like, N-terminal domain [47823] (1)
          1. lambda integrase-like, N-terminal domain [47824] (1)
             1. Recombinase XerD [47827]
                1. Escherichia coli [47828] (1)
       8. Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain [47831] (1)
          1. Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain [47832] (1)
             1. Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain [47833]
                1. Escherichia coli [47834] (7)
   40. Retroviral matrix proteins [47835] (1)
       1. Retroviral matrix proteins [47836] (4)
          1. Immunodeficiency virus matrix proteins [47837] (1)
             1. HIV-1 matrix protein (HIV-1 MA, HIVp17, p17, MA) [47838]
                1. Human immunodeficiency virus type 1 [47839] (2)
          2. HTLV-II matrix protein [47842] (1)
             1. HTLV-II matrix protein [47843]
                1. Human T-cell leukemia virus type 2 [47844] (1)
          3. Mason-Pfizer monkey virus matrix protein [47845] (1)
             1. Mason-Pfizer monkey virus matrix protein [47846]
                1. Simian Mason-Pfizer virus [47847] (1)
          4. GAG polyprotein M-domain [47848] (1)
             1. GAG polyprotein M-domain [47849]
                1. Rous sarcoma virus [47850] (1)
   41. Apolipophorin-III [47856] (1)
       1. Apolipophorin-III [47857] (1)
          1. Apolipophorin-III [47858] (1)
             1. Apolipophorin-III [47859]
                1. African locust (Locusta migratoria) [47860] (1)
   42. Saposin-like [47861] (1)
       1. Saposin [47862] (1)
          1. NKL-like [47863] (1)
             1. NK-lysin, NKL [47864]
                1. Pig (Sus scrofa) [47865] (1)
   43. Annexin [47873] (1)
       1. Annexin [47874] (1)
          1. Annexin [47875] (7)
             1. Annexin I [47876]
                1. Human (Homo sapiens) [47877] (1)
             2. Annexin III [47879]
                1. Human (Homo sapiens) [47880] (2)
             3. Annexin IV [47881]
                1. Cow (Bos taurus) [47882] (2)
             4. Annexin V [47883]
                1. Chicken (Gallus gallus) [47884] (1)
                2. Human (Homo sapiens) [47885] (6)
                3. Rat (Rattus norvegicus) [47886] (9)
             5. Annexin VI [47887]
                1. Cow (Bos taurus) [47888] (2)
   44. Transducin (alpha subunit), insertion domain [47894] (1)
       1. Transducin (alpha subunit), insertion domain [47895] (1)
          1. Transducin (alpha subunit), insertion domain [47896] (2)
             1. Transducin (alpha subunit), insertion domain [47897]
                1. Cow (Bos taurus) [47898] (1)
                2. Rat (Rattus norvegicus) [47899] (10)
   45. N-terminal domain of the delta subunit of the F1F0-ATP synthase [47927] (1)
       1. N-terminal domain of the delta subunit of the F1F0-ATP synthase [47928] (1)
          1. N-terminal domain of the delta subunit of the F1F0-ATP synthase [47929] (1)
             1. N-terminal domain of the delta subunit of the F1F0-ATP synthase [47930]
                1. Escherichia coli [47931] (1)
   46. Retrovirus capsid protein, N-terminal core domain [47942] (1)
       1. Retrovirus capsid protein, N-terminal core domain [47943] (1)
          1. Retrovirus capsid protein, N-terminal core domain [47944] (1)
             1. EIAV capsid protein p26 [47947]
                1. Equine infectious anemia virus [47948] (1)
   47. Cyclin-like [47953] (1)
       1. Cyclin-like [47954] (3)
          1. Cyclin [47955] (2)
             1. Cyclin A [47956]
                1. Cow (Bos taurus) [47958] (2)
             2. Cyclin H (mcs2) [47959]
                1. Human (Homo sapiens) [47960] (4)
          2. Transcription factor IIB (TFIIB), core domain [47965] (1)
             1. Transcription factor IIB (TFIIB), core domain [47966]
                1. Human (Homo sapiens) [47967] (2)
          3. Retinoblastoma tumor suppressor domains [47969] (1)
             1. Retinoblastoma tumor suppressor domains [47970]
                1. Human (Homo sapiens) [47971] (1)
   48. Ribosomal protein S7 [47972] (1)
       1. Ribosomal protein S7 [47973] (1)
          1. Ribosomal protein S7 [47974] (2)
             1. Ribosomal protein S7 [47975]
                1. Bacillus stearothermophilus [47976] (1)
                2. Thermus thermophilus [47977] (1)
   49. DNA polymerase III clamp loader subunits, C-terminal domain [48018] (1)
       1. DNA polymerase III clamp loader subunits, C-terminal domain [48019] (1)
          1. DNA polymerase III clamp loader subunits, C-terminal domain [48020] (3)
             1. delta prime subunit [48021]
                1. Escherichia coli [48022] (1)
             2. delta subunit [63580]
                1. Escherichia coli [63581] (4)
             3. Replication factor C4 [109896]
                1. Baker's yeast (Saccharomyces cerevisiae) [109897] (1)
   50. Iron-dependent repressor protein, dimerization domain [47978] (1)
       1. Iron-dependent repressor protein, dimerization domain [47979] (1)
          1. Iron-dependent repressor protein, dimerization domain [47980] (1)
             1. Diphtheria toxin repressor (DtxR) [47981]
                1. Corynebacterium diphtheriae [47982] (4)
   51. DEATH domain [47985] (1)
       1. DEATH domain [47986] (3)
          1. DEATH domain, DD [81312] (2)
             1. p75 low affinity neurotrophin receptor [47988]
                1. Rat (Rattus norvegicus) [47989] (1)
             2. Fas [47990]
                1. Human (Homo sapiens) [47991] (1)
          2. DEATH effector domain, DED [81388] (1)
             1. FADD (Mort1) [81387]
                1. Human (Homo sapiens) [81386] (2)
          3. Caspase recruitment domain, CARD [81313] (1)
             1. Raidd CARD domain [47995]
                1. Human (Homo sapiens) [47996] (1)
   52. Guanido kinase N-terminal domain [48033] (1)
       1. Guanido kinase N-terminal domain [48034] (1)
          1. Guanido kinase N-terminal domain [48035] (1)
             1. Arginine kinase, N-domain [48042]
                1. Horseshoe crab (Limulus polyphemus) [48043] (1)
   53. Hemocyanin, N-terminal domain [48049] (1)
       1. Hemocyanin, N-terminal domain [48050] (1)
          1. Hemocyanin, N-terminal domain [48051] (2)
             1. Hemocyanin, N-terminal domain [48052]
                1. Horseshoe crab (Limulus polyphemus) [48053] (4)
                2. Spiny lobster (Panulirus interruptus) [48054] (7)
   54. Di-copper centre-containing domain [48055] (1)
       1. Di-copper centre-containing domain [48056] (1)
          1. Hemocyanin middle domain [48057] (2)
             1. Arthropod hemocyanin [48058]
                1. Horseshoe crab (Limulus polyphemus) [48059] (4)
                2. Spiny lobster (Panulirus interruptus) [48060] (7)
   55. Transcription factor STAT-4 N-domain [48091] (1)
       1. Transcription factor STAT-4 N-domain [48092] (1)
          1. Transcription factor STAT-4 N-domain [48093] (1)
             1. Transcription factor STAT-4 N-domain [48094]
                1. Mouse (Mus musculus) [48095] (1)
   56. Heme-dependent peroxidases [48112] (1)
       1. Heme-dependent peroxidases [48113] (2)
          1. CCP-like [48114] (5)
             1. Fungal peroxidase (ligninase) [88935]
                1. White rot basidiomycete (Phanerochaete chrysosporium) [48116] (1)
                2. Arthromyces ramosus [48118] (9)
                3. Basidomycetos fungus (Phanerochaete chrysosporium) [48122] (3)
             2. Cytochrome c peroxidase, CCP [48119]
                1. Baker's yeast (Saccharomyces cerevisiae) [48120] (59)
             3. Plant peroxidase [48125]
                1. Barley (Hordeum vulgare), peroxidase 1 [48129] (1)
          2. Myeloperoxidase-like [48132] (1)
             1. Prostaglandin H2 synthase [48136]
                1. Sheep (Ovis aries) [48137] (1)
   57. DNA-glycosylase [48149] (1)
       1. DNA-glycosylase [48150] (2)
          1. Endonuclease III [48151] (1)
             1. Endonuclease III [48152]
                1. Escherichia coli [48153] (1)
          2. Mismatch glycosylase [48154] (1)
             1. Catalytic domain of MutY [48155]
                1. Escherichia coli [48156] (1)
   58. An anticodon-binding domain of class I aminoacyl-tRNA synthetases [48162] (1)
       1. An anticodon-binding domain of class I aminoacyl-tRNA synthetases [48163] (1)
          1. C-terminal domain of glutamyl-tRNA synthetase (GluRS) [48164] (1)
             1. C-terminal domain of glutamyl-tRNA synthetase (GluRS) [48165]
                1. Thermus thermophilus [48166] (1)
   59. R1 subunit of ribonucleotide reductase, N-terminal domain [48167] (1)
       1. R1 subunit of ribonucleotide reductase, N-terminal domain [48168] (1)
          1. R1 subunit of ribonucleotide reductase, N-terminal domain [48169] (1)
             1. R1 subunit of ribonucleotide reductase, N-terminal domain [48170]
                1. Escherichia coli [48171] (1)
   60. Cryptochrome/photolyase FAD-binding domain [48172] (1)
       1. Cryptochrome/photolyase FAD-binding domain [48173] (1)
          1. Cryptochrome/photolyase FAD-binding domain [48174] (1)
             1. C-terminal domain of DNA photolyase [48175]
                1. Anacystis nidulans [48177] (1)
   61. 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1)
       1. 6-phosphogluconate dehydrogenase C-terminal domain-like [48179] (3)
          1. Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain [48180] (1)
             1. 6-phosphogluconate dehydrogenase (6PGD) [48181]
                1. Sheep (Ovis orientalis aries) [48182] (5)
          2. HCDH C-domain-like [48187] (1)
             1. Fatty oxidation complex alpha subunit, C-terminal domain [109949]
                1. Pseudomonas fragi [109950] (6)
          3. N-(1-D-carboxylethyl)-L-norvaline dehydrogenase [48194] (1)
             1. N-(1-D-carboxylethyl)-L-norvaline dehydrogenase [48195]
                1. Arthrobacter, strain 1c [48196] (1)
   62. Uteroglobin-like [48200] (1)
       1. Uteroglobin-like [48201] (1)
          1. Uteroglobin-like [48202] (2)
             1. Uteroglobin [48203]
                1. Rabbit (Oryctolagus cuniculus) [48204] (1)
             2. Clara cell 17kDa protein [48205]
                1. Rat (Rattus norvegicus) [48206] (1)
   63. alpha/alpha toroid [48207] (2)
       1. Six-hairpin glycosidases [48208] (2)
          1. Glucoamylase [48209] (2)
             1. Glucoamylase [48210]
                1. Aspergillus awamori, variant x100 [48211] (6)
                2. Baker's yeast (Saccharomycopsis fibuligera) [48212] (1)
          2. Cellulases catalytic domain [48213] (3)
             1. CelA cellulase [48214]
                1. Clostridium thermocellum [48215] (1)
             2. CelD cellulase, C-terminal domain [48218]
                1. Clostridium thermocellum [48219] (1)
             3. Processive endocellulase CelF (Cel48F) [48220]
                1. Clostridium cellulolyticum [48221] (1)
       2. Terpenoid cyclases/Protein prenyltransferases [48239] (3)
          1. Terpenoid cyclase N-terminal domain [48240] (1)
             1. 5-Epi-aristolochene synthase [48241]
                1. Tobacco (Nicotiana tabacum) [48242] (3)
          2. Terpene synthases [48243] (1)
             1. Squalene-hopene cyclase [48244]
                1. Alicyclobacillus acidocaldarius [48245] (2)
          3. Complement components [48251] (1)
             1. C3D, a C3 fragment and ligand for complement receptor 2 [48252]
                1. Human (Homo sapiens) [48253] (1)
   64. Citrate synthase [48255] (1)
       1. Citrate synthase [48256] (1)
          1. Citrate synthase [48257] (3)
             1. Citrate synthase [48258]
                1. Chicken (Gallus gallus) [48259] (12)
                2. Pig (Sus scrofa) [48260] (2)
                3. Antarctic bacterium DS2-3R [48262] (1)
   65. Cytochrome P450 [48263] (1)
       1. Cytochrome P450 [48264] (1)
          1. Cytochrome P450 [48265] (4)
             1. Cytochrome P450-CAM [48266]
                1. Pseudomonas putida [48267] (22)
             2. Cytochrome P450-NOR, nitric reductase [48270]
                1. Fungus (Fusarium oxysporum) [48271] (2)
             3. Cytochrome P450-ERYF [48272]
                1. Saccaropolyspora erythraea [48273] (1)
             4. Cytochrome P450-TERP [48274]
                1. Pseudomonas sp. [48275] (1)
   66. Acid phosphatase/Vanadium-dependent haloperoxidase [48316] (1)
       1. Acid phosphatase/Vanadium-dependent haloperoxidase [48317] (1)
          1. Chloroperoxidase [48325] (1)
             1. Chloroperoxidase [48326]
                1. Curvularia inaequalis [48327] (7)
   67. H-NS histone-like proteins [81274] (1)
       1. H-NS histone-like proteins [81273] (1)
          1. H-NS histone-like proteins [81272] (1)
             1. H1 protein (H-NS) [47733]
                1. Escherichia coli [47734] (2)
   68. Sigma2 domain of RNA polymerase sigma factors [88945] (1)
       1. Sigma2 domain of RNA polymerase sigma factors [88946] (1)
          1. Sigma2 domain of RNA polymerase sigma factors [88947] (1)
             1. Sigma70 [88948]
                1. Escherichia coli [48332] (1)
   69. GTPase activation domain, GAP [48349] (1)
       1. GTPase activation domain, GAP [48350] (2)
          1. BCR-homology GTPase activation domain (BH-domain) [48351] (1)
             1. p50 RhoGAP domain [48352]
                1. Human (Homo sapiens) [48353] (1)
          2. p120GAP domain-like [48360] (1)
             1. p120GAP domain [48361]
                1. Human (Homo sapiens) [48362] (1)
   70. alpha-alpha superhelix [48370] (4)
       1. ARM repeat [48371] (2)
          1. Armadillo repeat [48372] (1)
             1. beta-Catenin [48373]
                1. Mouse (Mus musculus) [48374] (2)
          2. Leucine-rich repeat variant [48396] (1)
             1. Leucine-rich repeat variant [48397]
                1. Azotobacter vinelandii [48398] (1)
       2. Sec7 domain [48425] (1)
          1. Sec7 domain [48426] (2)
             1. Exchange factor ARNO [48427]
                1. Human (Homo sapiens) [48428] (1)
             2. Cytohesin-1/b2-1 [48429]
                1. Human (Homo sapiens) [48430] (1)
       3. Bacterial muramidases [48435] (1)
          1. Bacterial muramidases [48436] (1)
             1. 70 KDa soluble lytic transglycosylase (SLT70), superhelical domain [48437]
                1. Escherichia coli [48438] (1)
       4. TPR-like [48452] (1)
          1. Tetratricopeptide repeat (TPR) [48453] (1)
             1. Protein phosphatase 5 [48454]
                1. Human (Homo sapiens) [48455] (1)
   71. Lipoxigenase [48483] (1)
       1. Lipoxigenase [48484] (2)
          1. Plant lipoxigenases [48485] (2)
             1. Lipoxigenase, C-terminal domain [48486]
                1. Soybean (Glycine max), isozyme L1 [48487] (1)
                2. Soybean (Glycine max), isozyme L3 [48488] (4)
          2. Animal lipoxigenases [48489] (1)
             1. 15-Lipoxygenase [48490]
                1. Rabbit (Oryctolagus cuniculus) [48491] (1)
   72. Tetracyclin repressor-like, C-terminal domain [48497] (1)
       1. Tetracyclin repressor-like, C-terminal domain [48498] (1)
          1. Tetracyclin repressor-like, C-terminal domain [48499] (1)
             1. Tetracyclin repressor (Tet-repressor, TetR) [48500]
                1. Escherichia coli [48501] (6)
   73. Nuclear receptor ligand-binding domain [48507] (1)
       1. Nuclear receptor ligand-binding domain [48508] (1)
          1. Nuclear receptor ligand-binding domain [48509] (2)
             1. Retinoid-X receptor alpha (RXR-alpha) [48510]
                1. Human (Homo sapiens) [48511] (1)
             2. Retinoic acid receptor gamma (RAR-gamma) [48515]
                1. Human (Homo sapiens) [48516] (3)
   74. Phospholipase C/P1 nuclease [48536] (1)
       1. Phospholipase C/P1 nuclease [48537] (2)
          1. Phospholipase C [48538] (2)
             1. Bacterial phosholipase C [48539]
                1. Bacillus cereus [48540] (1)
             2. Alpha-toxin, N-terminal domain [48541]
                1. Clostridium perfringens, different strains [48542] (1)
          2. P1 nuclease [48543] (1)
             1. P1 nuclease [48544]
                1. Penicillium citrinum [48545] (1)
   75. Serum albumin-like [48551] (1)
       1. Serum albumin-like [48552] (1)
          1. Serum albumin-like [48553] (1)
             1. Serum albumin [48554]
                1. Human (Homo sapiens) [48555] (9)
   76. L-aspartase-like [48556] (1)
       1. L-aspartase-like [48557] (1)
          1. L-aspartase/fumarase [48558] (1)
             1. Fumarase [48561]
                1. Baker's yeast (Saccharomyces cerevisiae) [48563] (1)
   77. Terpenoid synthases [48575] (1)
       1. Terpenoid synthases [48576] (2)
          1. Isoprenyl diphosphate synthases [48577] (1)
             1. Farnesyl diphosphate synthase (geranyltranstransferase) [48578]
                1. Chicken (Gallus gallus) [48579] (5)
          2. Terpenoid cyclase C-terminal domain [48583] (1)
             1. 5-Epi-aristolochene synthase [48584]
                1. Tobacco (Nicotiana tabacum) [48585] (3)
   78. GroEL equatorial domain-like [48591] (1)
       1. GroEL equatorial domain-like [48592] (1)
          1. GroEL chaperone, ATPase domain [48593] (1)
             1. GroEL, E domain [48594]
                1. Escherichia coli [48595] (1)
   79. Cysteine alpha-hairpin motif [47071] (1)
       1. Cysteine alpha-hairpin motif [47072] (1)
          1. p8-MTCP1 [47073] (1)
             1. p8-MTCP1 [47074]
                1. Human (Homo sapiens) [47075] (2)
   80. Phospholipase A2, PLA2 [48618] (1)
       1. Phospholipase A2, PLA2 [48619] (2)
          1. Vertebrate phospholipase A2 [48623] (10)
             1. Snake phospholipase A2 [48624]
                1. Taiwan cobra (Naja naja atra) [48625] (1)
                2. Indian cobra (Naja naja naja) [48626] (1)
                3. Chinese water moccasin (Agkistrodon halys pallas), different isoforms [48628] (2)
                4. Eastern cottonmouth snake (Agkistridon piscivorus) [48629] (1)
                5. Mainland tiger snake (Notechis scutatus scutatus), notexin [48631] (1)
                6. Russell's viper (Vipera russelli) [48634] (1)
                7. Sand viper (Vipera ammodytes meridionalis), vipoxin inhibitor [88517] (1)
             2. Phospholipase A2 [48637]
                1. Human (Homo sapiens), synovial fluid [48638] (2)
                2. Cow (Bos taurus), pancreas [48639] (17)
                3. Pig (Sus scrofa), pancreas [48640] (6)
          2. Insect phospholipase A2 [48620] (1)
             1. Phospholipase A2 [48621]
                1. European honeybee (Apis mellifera) [48622] (1)
   81. Fungal elicitin [48646] (1)
       1. Fungal elicitin [48647] (1)
          1. Fungal elicitin [48648] (1)
             1. beta-cryptogein [48649]
                1. Phytophthora cryptogea [48650] (3)
   82. Multiheme cytochromes [48694] (1)
       1. Multiheme cytochromes [48695] (2)
          1. Cytochrome c3-like [48696] (5)
             1. Cytochrome c3 [48697]
                1. Desulfovibrio desulfuricans, different strains [48698] (3)
                2. Desulfovibrio vulgaris [48699] (3)
                3. Desulfovibrio gigas [48700] (1)
                4. Desulfomicrobium norvegicum [48702] (1)
             2. Cytochrome c7 (cytochrome c551.5, PpcA) [48703]
                1. Desulfuromonas acetoxidans [48704] (2)
          2. Di-heme elbow motif [48711] (1)
             1. Cytochrome c554 [48714]
                1. Nitrosomonas europaea [48715] (1)
2. All beta proteins [48724] (62)
   1. Immunoglobulin-like beta-sandwich [48725] (8)
      1. Immunoglobulin [48726] (4)
         1. V set domains (antibody variable domain-like) [48727] (17)
            1. Immunoglobulin light chain kappa variable domain, VL-kappa [88519]
               1. Human (Homo sapiens), cluster 1 [88520] (1)
               2. Human (Homo sapiens), cluster 2 [88521] (3)
               3. Mouse (Mus musculus), cluster 1.1 [88524] (2)
               4. Mouse (Mus musculus), cluster 1.2 [88525] (1)
               5. Engineered (including hybrid species) [88533] (1)
            2. Immunoglobulin light chain lambda variable domain, VL-lambda [88534]
               1. Human (Homo sapiens), cluster 2 [88536] (2)
               2. Mouse (Mus musculus) [88541] (1)
            3. Immunoglobulin heavy chain variable domain, VH [88543]
               1. Mouse (Mus musculus), cluster 3.2 [88552] (1)
               2. Engineered (including hybrid species) [88562] (1)
            4. Camelid IG heavy chain variable domain, VHh [88563]
               1. Llama (Lama glama) [88565] (1)
            5. T-cell antigen receptor [48933]
               1. Mouse (Mus musculus), beta-chain [48936] (1)
            6. Immunoreceptor CTLA-4 (CD152), N-terminal fragment [48939]
               1. Human (Homo sapiens) [48940] (1)
            7. Myelin membrane adhesion molecule P0 [48728]
               1. Rat (Rattus norvegicus) [48729] (1)
            8. CD8 [48734]
               1. Human (Homo sapiens) [48735] (1)
            9. CD4 V-set domains [48737]
               1. Human (Homo sapiens) [48738] (6)
               2. Rat (Rattus rattus) [48739] (1)
            10. CD2, first domain [48740]
                1. Human (Homo sapiens) [48741] (3)
         2. C1 set domains (antibody constant domain-like) [48942] (5)
            1. Immunoglobulin light chain kappa constant domain, CL-kappa [88566]
               1. Mouse (Mus musculus) [88567] (1)
               2. Human (Homo sapiens) [88569] (17)
            2. Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma [88589]
               1. Guinea pig (Cavia porcellus) [49123] (1)
            3. T-cell antigen receptor [49125]
               1. Mouse (Mus musculus), beta-chain [49128] (1)
            4. beta2-microglobulin [88600]
               1. Cow (Bos taurus) [48946] (1)
         3. C2 set domains [49142] (5)
            1. Intercellular cell adhesion molecule-1 (ICAM-1) [49145]
               1. Human (Homo sapiens) [49146] (1)
            2. Intercellular cell adhesion molecule-2 (ICAM-2) [49147]
               1. Human (Homo sapiens) [49148] (1)
            3. CD4 C2-set domains [49149]
               1. Human (Homo sapiens) [49150] (6)
               2. Rat (Rattus rattus) [49151] (1)
            4. CD2, second domain [49152]
               1. Human (Homo sapiens) [49153] (1)
         4. I set domains [49159] (9)
            1. Intercellular adhesion molecule-1, ICAM-1 [49162]
               1. Human (Homo sapiens) [49163] (1)
            2. Intercellular adhesion molecule-2, ICAM-2 [49164]
               1. Human (Homo sapiens) [49165] (1)
            3. Neural cell adhesion molecule (NCAM) [49166]
               1. Rat (Rattus norvegicus) [49167] (1)
            4. Telokin [49170]
               1. Turkey (Meleagris gallopavo) [49171] (1)
            5. Titin [49172]
               1. Human (Homo sapiens), different modules [49173] (4)
            6. Twitchin [49174]
               1. Nematode (Caenorhabditis elegans) [49175] (3)
               2. Human (Homo sapiens), Ig repeat 27 [49176] (2)
            7. Killer cell inhibitory receptor [49202]
               1. Human (Homo sapiens), kir2dl3 [49203] (2)
               2. Human (Homo sapiens), p58-cl42 kir [49204] (2)
      2. E set domains [81296] (7)
         1. NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain [81279] (1)
            1. p50 subunit of NF-kappa B transcription factor [49248]
               1. Mouse (Mus musculus) [49250] (1)
         2. E-set domains of sugar-utilizing enzymes [81282] (9)
            1. Galactose oxidase, C-terminal domain [49209]
               1. Dactylium dendroides [49210] (3)
            2. Sialidase, "linker" domain [49237]
               1. Micromonospora viridifaciens [49238] (2)
            3. CelD cellulase, N-terminal domain [49231]
               1. Clostridium thermocellum [49232] (1)
            4. Bacterial chitobiase (N-acetyl-beta-glucoseaminidase), C-terminal domain [49211]
               1. Serratia marcescens [49212] (2)
            5. Cyclomaltodextrin glycanotransferase, domain D [49215]
               1. Bacillus circulans, different strains [49216] (18)
               2. Bacillus stearothermophilus [49217] (1)
               3. Thermoanaerobacterium thermosulfurigenes, EM1 [49220] (2)
            6. Isoamylase, N-terminal domain N [49226]
               1. Pseudomonas amyloderamosa [49227] (1)
            7. Chitinase A, N-terminal domain N [49233]
               1. Serratia marcescens [49234] (1)
         3. Arthropod hemocyanin, C-terminal domain [81283] (2)
            1. Arthropod hemocyanin, C-terminal domain [49228]
               1. Horseshoe crab (Limulus polyphemus) [49229] (4)
               2. Spiny lobster (Panulirus interruptus) [49230] (7)
         4. Class II viral fusion proteins C-terminal domain [81284] (1)
            1. Envelope glycoprotein [49213]
               1. Tick-borne encephalitis virus [49214] (1)
         5. ML domain [81287] (2)
            1. Major mite allergen [49256]
               1. House-dust mite (Dermatophagoides farinae), Der f 2 [49257] (2)
               2. House-dust mite (Dermatophagoides pteronyssinus), Der p 2 [49258] (1)
         6. RhoGDI-like [81288] (1)
            1. Rho GDP-dissociation inhibitor 1, RhoGDI [49241]
               1. Cow (Bos taurus) [49243] (2)
         7. Filamin repeat (rod domain) [81290] (1)
            1. F-actin cross-linking gelation factor (ABP-120) repeats [49239]
               1. Slime mold (Dictyostelium discoideum) [49240] (1)
      3. Fibronectin type III [49265] (1)
         1. Fibronectin type III [49266] (8)
            1. Extracellular region of human tissue factor [49267]
               1. Human (Homo sapiens) [49268] (4)
            2. Fibronectin, different Fn3 modules [49270]
               1. Human (Homo sapiens) [49271] (7)
               2. Mouse (Mus musculus) [49272] (4)
            3. Tenascin [49273]
               1. Human (Homo sapiens) [49275] (1)
            4. Neuroglian, two amino proximal Fn3 repeats [49276]
               1. Drosophila melanogaster [49277] (2)
            5. Granulocyte colony-stimulating factor (GC-SF) receptor [49291]
               1. Mouse (Mus musculus) [49292] (2)
            6. Cytokine receptor gp130 cytokine-binding domains [49295]
               1. Human (Homo sapiens) [49296] (1)
            7. Type I titin module [49297]
               1. Human (Homo sapiens) [49298] (1)
      4. Cadherin-like [49313] (1)
         1. Cadherin [49314] (2)
            1. N-cadherin (neural) [49315]
               1. Mouse (Mus musculus) [49316] (1)
            2. E-cadherin (epithelial) [49317]
               1. Mouse (Mus musculus) [49318] (1)
      5. Actinoxanthin-like [49319] (1)
         1. Actinoxanthin-like [49320] (4)
            1. Macromycin [49321]
               1. Streptomyces macromomyceticus [49322] (1)
            2. Neocarzinostatin [49323]
               1. Streptomyces carzinostaticus [49324] (1)
            3. Actinoxanthin [49325]
               1. Actinomyces globisporus, number 1131 [49326] (1)
            4. Kedarcidin [49327]
               1. Actimomycete, strain L585-6 [49328] (1)
      6. Cu,Zn superoxide dismutase-like [49329] (1)
         1. Cu,Zn superoxide dismutase-like [49330] (3)
            1. Cu,Zn superoxide dismutase, SOD [49331]
               1. Human (Homo sapiens) [49333] (1)
               2. Baker's yeast (Saccharomyces cerevisiae) [49336] (3)
               3. Escherichia coli [49338] (1)
      7. PapD-like [49354] (1)
         1. Pilus chaperone [49355] (2)
            1. Pilus chaperone PapD, N-domain [49356]
               1. Escherichia coli [49357] (1)
            2. Periplasmic chaperone FimC [49358]
               1. Escherichia coli [49359] (1)
      8. Superoxide reductase-like [49367] (1)
         1. Superoxide reductase-like [49368] (1)
            1. Desulfoferrodoxin C-terminal domain [49371]
               1. Desulfovibrio desulfuricans [49372] (1)
   2. Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (5)
      1. Diphtheria toxin, C-terminal domain [49380] (1)
         1. Diphtheria toxin, C-terminal domain [49381] (1)
            1. Diphtheria toxin, C-terminal domain [49382]
               1. Corynebacterium diphtheriae [49383] (2)
      2. Carbohydrate-binding domain [49384] (3)
         1. Cellulose-binding domain family II [49385] (2)
            1. Exo-1,4-beta-D-glycanase (cellulase, xylanase), cellulose-binding domain, CBD [49386]
               1. Cellulomonas fimi [49387] (2)
            2. Endo-1,4-beta xylanase D, xylan binding domain, XBD [49388]
               1. Cellulomonas fimi [49389] (2)
         2. Cellulose-binding domain family III [49390] (1)
            1. Cohesin domain [49396]
               1. Clostridium thermocellum, cellulosome, various modules [49397] (1)
         3. Bacterial chitobiase, n-terminal domain [49398] (1)
            1. Bacterial chitobiase, n-terminal domain [49399]
               1. Serratia marcescens [49400] (2)
      3. Bacterial adhesins [49401] (1)
         1. Collagen-binding domain of adhesin [49402] (1)
            1. Collagen-binding domain of adhesin [49403]
               1. Staphylococcus aureus [49404] (1)
      4. p53-like transcription factors [49417] (1)
         1. Rel/Dorsal transcription factors, DNA-binding domain [81315] (1)
            1. T-cell transcription factor NFAT1 (NFATC), DNA-binding domain [49421]
               1. Human (Homo sapiens) [49422] (1)
      5. Cytochrome f, large domain [49441] (1)
         1. Cytochrome f, large domain [49442] (1)
            1. Cytochrome f, large domain [49443]
               1. Turnip (Brassica rapa) [49444] (2)
   3. Prealbumin-like [49451] (1)
      1. Starch-binding domain-like [49452] (1)
         1. Starch-binding domain [49453] (4)
            1. Cyclodextrin glycosyltransferase, C-terminal domain [49454]
               1. Bacillus circulans, different strains [49455] (18)
               2. Bacillus stearothermophilus [49456] (1)
               3. Thermoanaerobacterium thermosulfurigenes, EM1 [49459] (2)
            2. Glucoamylase, granular starch-binding domain [49460]
               1. Aspergillus niger [49461] (4)
   4. alpha-Amylase inhibitor tendamistat [49497] (1)
      1. alpha-Amylase inhibitor tendamistat [49498] (1)
         1. alpha-Amylase inhibitor tendamistat [49499] (1)
            1. alpha-Amylase inhibitor tendamistat [49500]
               1. Streptomyces tendae [49501] (4)
   5. Cupredoxin-like [49502] (1)
      1. Cupredoxins [49503] (3)
         1. Plastocyanin/azurin-like [49504] (19)
            1. Amicyanin [49505]
               1. Paracoccus denitrificans [49506] (3)
            2. Plastocyanin [49507]
               1. Poplar (Populus nigra), variant italica [49508] (8)
               2. French bean (Phaseolus vulgaris) [49509] (1)
               3. Parsley (Petroselinum crispum) [49510] (2)
               4. Spinach (Spinacia oleracea) [49511] (1)
               5. Sea lettuce (Ulva pertusa) [49513] (1)
               6. Green alga (Chlamydomonas reinhardtii) [49514] (1)
               7. Green alga (Enteromorpha prolifera) [49515] (1)
               8. Fern (Adiantum capillus-veneris) [49516] (2)
               9. Anabaena variabilis [49517] (1)
               10. Cyanobacterium (Synechocystis sp.), pcc 6803 [49519] (1)
            3. Pseudoazurin [49522]
               1. Alcaligenes faecalis, strain s-6 [49523] (10)
               2. Methylobacterium extorquens, strain am1 [49524] (1)
               3. Achromobacter cycloclastes [49525] (4)
            4. Plantacyanin [49527]
               1. Cucumber (Cucumis sativus) [49528] (1)
            5. Azurin [49530]
               1. Pseudomonas aeruginosa [49533] (1)
               2. Pseudomonas fluorescens [49534] (1)
            6. Rusticyanin [49537]
               1. Thiobacillus ferrooxidans [49538] (4)
            7. Stellacyanin [49539]
               1. Cucumber (Cucumis sativus) [49540] (1)
         2. Periplasmic domain of cytochrome c oxidase subunit II [49541] (1)
            1. Quinol oxidase (CyoA) [49542]
               1. Escherichia coli [49543] (2)
         3. Multidomain cupredoxins [49550] (4)
            1. Nitrite reductase, NIR [49551]
               1. Achromobacter cycloclastes [49552] (10)
               2. Alcaligenes faecalis, strain s-6 [49553] (2)
               3. Alcaligenes xylosoxidans [49554] (2)
            2. Ceruloplasmin [49559]
               1. Human (Homo sapiens) [49560] (6)
   6. C2 domain-like [49561] (3)
      1. C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (2)
         1. PLC-like (P variant) [49563] (1)
            1. Domain from cytosolic phospholipase A2 [49566]
               1. Human (Homo sapiens) [49567] (2)
         2. Synaptotagmin-like (S variant) [49575] (1)
            1. Synaptogamin I [49576]
               1. Rat (Rattus norvegicus) [49577] (1)
      2. Periplasmic chaperone C-domain [49584] (1)
         1. Periplasmic chaperone C-domain [49585] (2)
            1. PapD [49586]
               1. Escherichia coli [49587] (1)
            2. FimC [49588]
               1. Escherichia coli [49589] (1)
      3. PHL pollen allergen [49590] (1)
         1. PHL pollen allergen [49591] (1)
            1. PHL P 2 [49592]
               1. Timothy grass (Phleum pratense) [49593] (3)
   7. Nucleoplasmin-like/VP (viral coat and capsid proteins) [88632] (2)
      1. ssDNA viruses [88645] (3)
         1. Microviridae-like VP [49612] (1)
            1. Microvirus capsid proteins [49613]
               1. Bacteriophage phi-X174 [49614] (1)
         2. Parvoviridae-like VP [88646] (2)
            1. Parvovirus (panleukopenia virus) capsid protein [49661]
               1. Feline panleukopenia virus, strain b [49689] (1)
               2. Canine parvovirus [49662] (1)
         3. Densovirinae-like VP [88647] (1)
            1. Densovirus capsid protein [49652]
               1. Galleria mellonella densovirus [49653] (1)
      2. PHM/PNGase F [49742] (2)
         1. Glycosyl-asparaginase [49743] (1)
            1. Peptide:N-glycosidase F, PNGase F [49744]
               1. Flavobacterium meningosepticum [49745] (6)
         2. Peptidylglycine alpha-hydroxylating monooxygenase, PHM [49746] (1)
            1. Peptidylglycine alpha-hydroxylating monooxygenase, PHM [63402]
               1. Rat (Rattus norvegicus) [49748] (2)
   8. gamma-Crystallin-like [49694] (1)
      1. gamma-Crystallin-like [49695] (3)
         1. Crystallins/Ca-binding development proteins [49696] (5)
            1. gamma-Crystallin [49697]
               1. Cow (Bos taurus), isoform II (B) [49698] (7)
               2. Cow (Bos taurus), isoform F [49701] (2)
            2. beta-Crystallin [49702]
               1. Cow (Bos taurus) [49703] (2)
            3. Protein S [49706]
               1. Myxococcus xanthus [49707] (4)
            4. Spherulin 3a (S3a) [49708]
               1. Slime mold (Physarum polycephalum) [49709] (1)
         2. Yeast killer toxin [49710] (1)
            1. Yeast killer toxin [49711]
               1. Williopsis mrakii [49712] (1)
         3. Streptomyces metalloproteinase inhibitor, SMPI [49713] (1)
            1. Streptomyces metalloproteinase inhibitor, SMPI [49714]
               1. Streptomyces nigrescens [49715] (1)
   9. Lipase/lipooxygenase domain (PLAT/LH2 domain) [49722] (1)
      1. Lipase/lipooxygenase domain (PLAT/LH2 domain) [49723] (3)
         1. Lipoxigenase N-terminal domain [49724] (3)
            1. Plant lipoxigenase [49725]
               1. Soybean (Glycine max), isozyme L1 [49726] (1)
               2. Soybean (Glycine max), isozyme L3 [49727] (4)
            2. 15-Lipoxygenase [49728]
               1. Rabbit (Oryctolagus cuniculus) [49729] (1)
         2. Colipase-binding domain [49730] (2)
            1. Pancreatic lipase, C-terminal domain [49731]
               1. Guinea pig (Cavia porcellus) [49735] (1)
               2. Dog (Canis familiaris) [49736] (1)
         3. Alpha-toxin, C-terminal domain [49738] (1)
            1. Alpha-toxin, C-terminal domain [49739]
               1. Clostridium perfringens, different strains [49740] (1)
   10. Heat shock protein 70kD (HSP70), peptide-binding domain [100919] (1)
       1. Heat shock protein 70kD (HSP70), peptide-binding domain [100920] (1)
          1. Heat shock protein 70kD (HSP70), peptide-binding domain [100921] (1)
             1. DnaK [100922]
                1. Escherichia coli [100923] (2)
   11. Ecotin, trypsin inhibitor [49771] (1)
       1. Ecotin, trypsin inhibitor [49772] (1)
          1. Ecotin, trypsin inhibitor [49773] (1)
             1. Ecotin, trypsin inhibitor [49774]
                1. Escherichia coli [49775] (1)
   12. PEBP-like [49776] (1)
       1. PEBP-like [49777] (1)
          1. Phosphatidylethanolamine binding protein [49778] (1)
             1. Phosphatidylethanolamine binding protein, PEBP [49779]
                1. Cow (Bos taurus) [49781] (1)
   13. Galactose-binding domain-like [49784] (1)
       1. Galactose-binding domain-like [49785] (3)
          1. Galactose-binding domain [49786] (2)
             1. Galactose oxidase, N-terminal domain [49787]
                1. Dactylium dendroides [49788] (3)
             2. Sialidase, C-terminal domain [49789]
                1. Micromonospora viridifaciens [49790] (2)
          2. delta-Endotoxin, C-terminal domain [49796] (2)
             1. delta-Endotoxin, C-terminal domain [49797]
                1. Bacillus thuringiensis tenebrionis, CRYIIIA (BT13) [49798] (1)
                2. Bacillus thuringiensis, CRYIA (A) [49799] (1)
          3. CBM4/9 [74893] (1)
             1. Cellulose-binding domain of cellulase C [49809]
                1. Cellulomonas fimi [49810] (2)
   14. ENV polyprotein, receptor-binding domain [49829] (1)
       1. ENV polyprotein, receptor-binding domain [49830] (1)
          1. ENV polyprotein, receptor-binding domain [49831] (1)
             1. F-MuLV receptor-binding domain [49832]
                1. Friend murine leukemia virus [49833] (1)
   15. Virus attachment protein globular domain [49834] (1)
       1. Virus attachment protein globular domain [49835] (1)
          1. Adenovirus fiber protein "knob" domain [49836] (1)
             1. Adenovirus fiber protein "knob" domain [49837]
                1. Human adenovirus type 5 [49838] (1)
   16. TNF-like [49841] (1)
       1. TNF-like [49842] (1)
          1. TNF-like [49843] (1)
             1. Extracellular domain of CD40 ligand [49844]
                1. Human (Homo sapiens) [49845] (1)
   17. CUB-like [49853] (1)
       1. Spermadhesin, CUB domain [49854] (1)
          1. Spermadhesin, CUB domain [49855] (1)
             1. Acidic seminal fluid protein (ASFP) [49856]
                1. Cow (Bos taurus) [49857] (1)
   18. Osmotin, thaumatin-like protein [49869] (1)
       1. Osmotin, thaumatin-like protein [49870] (1)
          1. Osmotin, thaumatin-like protein [49871] (2)
             1. Pathogenesis-related protein 5d [49872]
                1. Common tobacco (Nicotiana tabacum) [49873] (1)
             2. Thaumatin [49876]
                1. Ketemfe (Thaumatococcus daniellii) [49877] (4)
   19. SMAD/FHA domain [49878] (1)
       1. SMAD/FHA domain [49879] (1)
          1. SMAD domain [49880] (1)
             1. Smad4 tumor suppressor C-terminal domain [49881]
                1. Human (Homo sapiens) [49882] (1)
   20. Concanavalin A-like lectins/glucanases [49898] (1)
       1. Concanavalin A-like lectins/glucanases [49899] (8)
          1. Legume lectins [49900] (5)
             1. Concanavalin A [49901]
                1. Jack bean (Canavalia ensiformis) [49902] (8)
             2. Legume lectin [49904]
                1. West-central african legume (Griffonia simplicifolia) [49907] (3)
                2. Coral tree (Erythrina corallodendron) [49908] (6)
                3. Soybean (Glycine max) [49913] (3)
                4. Horse gram (Dolichos biflorus), different isoforms [49915] (1)
          2. Glycosyl hydrolases family 16 [49925] (3)
             1. Bacillus 1-3,1-4-beta-glucanase [49926]
                1. Bacillus licheniformis [49927] (1)
                2. Hybrid protein: residues 1-16 from Bacillus amyloliquefaciens and Bacillus macerans [49928] (3)
                3. Bacillus macerans [49929] (2)
          3. Galectin (animal S-lectin) [49932] (2)
             1. Charcot-Leyden crystal (CLC) protein [49938]
                1. Human (Homo sapiens) [49939] (1)
             2. Galectin-3 CRD [49940]
                1. Human (Homo sapiens) [49941] (1)
          4. Clostridium neurotoxins, the second last domain [49956] (1)
             1. Tetanus neurotoxin [49957]
                1. Clostridium tetani [49958] (2)
          5. Vibrio cholerae sialidase, N-terminal and insertion domains [49965] (1)
             1. Vibrio cholerae sialidase, N-terminal and insertion domains [49966]
                1. Vibrio cholerae [49967] (2)
          6. Leech intramolecular trans-sialidase, N-terminal domain [49968] (1)
             1. Leech intramolecular trans-sialidase, N-terminal domain [49969]
                1. North american leech (Macrobdella decora) [49970] (5)
          7. Glycosyl hydrolase family 7 catalytic core [49971] (2)
             1. Cellobiohydrolase I (cellulase, Endoglucanase I, CBH1) [68900]
                1. Trichoderma reesei, Cel7A [68898] (4)
                2. Humicola insolens, Cel7b [49977] (1)
          8. Xylanase/endoglucanase 11/12 [49978] (6)
             1. Xylanase II [49979]
                1. Bacillus circulans [49980] (4)
                2. Trichoderma harzianum [49983] (1)
                3. Trichoderma reesei, xynI [49984] (1)
                4. Thermomyces lanuginosus [49986] (1)
                5. Aspergillus kawachii [49988] (1)
             2. Family 12 endo-1,4-beta-glucanase (cellulase) catalytic domain [49991]
                1. Streptomyces lividans, CelB2 [49992] (1)
   21. Supersandwich [49993] (1)
       1. Amine oxidase catalytic domain [49998] (1)
          1. Amine oxidase catalytic domain [49999] (1)
             1. Copper amine oxidase, domain 3 [50000]
                1. Arthrobacter globiformis [50003] (3)
   22. ISP domain [50021] (1)
       1. ISP domain [50022] (1)
          1. Rieske iron-sulfur protein (ISP) [50023] (2)
             1. ISP subunit of the mitochondrial cytochrome bc1-complex, water-soluble domain [50024]
                1. Cow (Bos taurus) [50025] (1)
             2. ISP subunit from chloroplast cytochrome bf complex [50027]
                1. Spinach (Spinacia oleracea) [50028] (1)
   23. SH3-like barrel [50036] (7)
       1. C-terminal domain of transcriptional repressors [50037] (2)
          1. Biotin repressor (BirA) [50038] (1)
             1. Biotin repressor/biotin holoenzyme synthetase, C-terminal domain [50039]
                1. Escherichia coli [50040] (2)
          2. Iron-dependent regulator [50041] (1)
             1. Diphtheria toxin repressor (DtxR) [50042]
                1. Corynebacterium diphtheriae [50043] (3)
       2. SH3-domain [50044] (1)
          1. SH3-domain [50045] (15)
             1. Fyn proto-oncogene tyrosine kinase, SH3 domain [50048]
                1. Human (Homo sapiens) [50049] (2)
             2. SH3 domain from nebulin [50050]
                1. Human (Homo sapiens) [50051] (2)
             3. Abl tyrosine kinase, SH3 domain [50052]
                1. Mouse (Mus musculus) [50053] (1)
                2. Human (Homo sapiens) [50054] (2)
             4. Phosphatidylinositol 3-kinase (p85-alpha subunit, pi3k), SH3 domain [50055]
                1. Human (Homo sapiens) [50056] (3)
                2. Cow (Bos taurus) [50057] (2)
             5. alpha-Spectrin, SH3 domain [50058]
                1. Chicken (Gallus gallus) [50059] (6)
             6. IL-2 inducible T-cell (Itc) kinase [50060]
                1. Mouse (Mus musculus) [50061] (1)
             7. Hemapoetic cell kinase Hck [50062]
                1. Human (Homo sapiens) [50063] (2)
             8. c-src protein tyrosine kinase [50064]
                1. Human (Homo sapiens) [50065] (2)
                2. Chicken (Gallus gallus) [50066] (3)
             9. Bruton's tyrosine kinase [50068]
                1. Human (Homo sapiens) [50069] (2)
             10. Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains [50070]
                 1. Human (Homo sapiens) [50071] (2)
             11. Phospholipase C, SH3 domain [50074]
                 1. Human (Homo sapiens) [50075] (2)
             12. Amphiphysin 2 [50080]
                 1. Rat (Rattus norvegicus) [50081] (1)
       3. Myosin S1 fragment, N-terminal domain [50084] (1)
          1. Myosin S1 fragment, N-terminal domain [50085] (1)
             1. Myosin S1 fragment, N-terminal domain [50086]
                1. Slime mold (Dictyostelium discoideum) [50089] (8)
       4. Chromo domain-like [54160] (2)
          1. "Histone-like" proteins from archaea [54161] (2)
             1. DNA-binding protein [54162]
                1. Archaeon Sulfolobus solfataricus, Sso7d [54163] (3)
                2. Archaeon Sulfolobus acidocaldarius, Sac7d [54164] (1)
          2. Chromo domain [54165] (1)
             1. Heterochromatin protein 1, HP1 [54166]
                1. Mouse (Mus musculus), HP1 beta (MOD1, M31) [54167] (1)
       5. Electron transport accessory proteins [50090] (2)
          1. R67 dihydrofolate reductase [50091] (1)
             1. R67 dihydrofolate reductase [50092]
                1. Escherichia coli, plasmid PLZ1 [50093] (2)
          2. Photosystem I accessory protein E (PsaE) [50094] (1)
             1. Photosystem I accessory protein E (PsaE) [50095]
                1. Cyanobacterium (Synechococcus sp.), pcc 7002 [50096] (2)
       6. Translation proteins SH3-like domain [50104] (1)
          1. eIF5a N-terminal domain-like [50110] (2)
             1. Eukaryotic initiation translation factor 5a (eIF5a) [50111]
                1. Archaeon Methanococcus jannaschii [50112] (1)
                2. Archaeon Pyrobaculum aerophilum [50113] (1)
       7. Cell growth inhibitor/plasmid maintenance toxic component [50118] (1)
          1. CcdB [50119] (1)
             1. CcdB [50120]
                1. Escherichia coli [50121] (2)
   24. GroES-like [50128] (1)
       1. GroES-like [50129] (1)
          1. Alcohol dehydrogenase-like, N-terminal domain [50136] (2)
             1. Alcohol dehydrogenase [50137]
                1. Horse (Equus caballus) [50138] (6)
             2. Hypothetical protein YhdH [101706]
                1. Escherichia coli [101707] (3)
   25. PDZ domain-like [50155] (1)
       1. PDZ domain-like [50156] (2)
          1. PDZ domain [50157] (1)
             1. Discs large protein homolog [50158]
                1. Human (Homo sapiens) [50159] (1)
          2. Interleukin 16 [50172] (1)
             1. Interleukin 16 [50173]
                1. Human (Homo sapiens) [50174] (1)
   26. N-terminal domains of the minor coat protein g3p [50175] (1)
       1. N-terminal domains of the minor coat protein g3p [50176] (1)
          1. N-terminal domains of the minor coat protein g3p [50177] (2)
             1. N-terminal domains of the minor coat protein g3p [50178]
                1. Bacteriophage M13 [50179] (2)
                2. Bacteriophage fd [50180] (1)
   27. Ribosomal protein L14 [50192] (1)
       1. Ribosomal protein L14 [50193] (1)
          1. Ribosomal protein L14 [50194] (1)
             1. Ribosomal protein L14 [50195]
                1. Bacillus stearothermophilus [50196] (1)
   28. OB-fold [50198] (5)
       1. Staphylococcal nuclease [50199] (1)
          1. Staphylococcal nuclease [50200] (1)
             1. Staphylococcal nuclease [50201]
                1. Staphylococcus aureus [50202] (38)
       2. Bacterial enterotoxins [50203] (2)
          1. Bacterial AB5 toxins, B-subunits [50204] (1)
             1. Verotoxin-1/shiga-toxin, B-pentamer [50210]
                1. Escherichia coli [50211] (1)
          2. Superantigen toxins, N-terminal domain [50219] (5)
             1. Staphylococcal enterotoxin C2, SEC2 [50222]
                1. Staphylococcus aureus [50223] (2)
             2. Toxic shock syndrome toxin-1 (TSST-1) [50224]
                1. Staphylococcus aureus [50225] (2)
             3. Staphylococcal enterotoxin B, SEB [50226]
                1. Staphylococcus aureus [50227] (3)
             4. Streptococcal superantigen Spe-C [50232]
                1. Streptococcus pyogenes [50233] (1)
             5. Streptococcal superantigen Smez-2 [50236]
                1. Streptococcus pyogenes [50237] (1)
       3. TIMP-like [50242] (1)
          1. Tissue inhibitor of metalloproteinases, TIMP [50243] (1)
             1. TIMP-2 [50246]
                1. Human (Homo sapiens) [50247] (2)
       4. Nucleic acid-binding proteins [50249] (6)
          1. Anticodon-binding domain [50250] (1)
             1. Lysyl-tRNA synthetase (LysRS) [50256]
                1. Escherichia coli, gene lysS [50257] (2)
          2. DNA helicase RuvA subunit, N-terminal domain [50259] (1)
             1. DNA helicase RuvA subunit, N-terminal domain [50260]
                1. Escherichia coli [50261] (2)
          3. Cold shock DNA-binding domain-like [50282] (8)
             1. Major cold shock protein [50283]
                1. Escherichia coli [50284] (1)
                2. Bacillus subtilis [50285] (4)
             2. S1 RNA-binding domain of polyribonucleotide phosphorylase, PNPase [50287]
                1. Escherichia coli [50288] (1)
             3. Translational initiation factor 1, IF1 [50290]
                1. Escherichia coli [50291] (1)
             4. Rho termination factor, RNA-binding domain [68910]
                1. Escherichia coli [68911] (2)
             5. C-terminal domain of eukaryotic initiation translation factor 5a (eIF5a) [50296]
                1. Archaeon Methanococcus jannaschii [50297] (1)
                2. Archaeon Pyrobaculum aerophilum [50298] (1)
             6. Ribosomal protein S17 [50304]
                1. Bacillus stearothermophilus [50306] (1)
          4. DNA ligase/mRNA capping enzyme postcatalytic domain [50307] (2)
             1. RNA guanylyltransferase (mRNA capping enzyme) [50308]
                1. Chlorella virus, PBCV-1 [50309] (1)
             2. ATP-dependent DNA ligase [50310]
                1. Bacteriophage T7 [50311] (1)
          5. Phage ssDNA-binding proteins [50315] (2)
             1. Gene V protein [50316]
                1. Filamentous bacteriophage (f1, M13) [50317] (16)
             2. Gene 32 protein (gp32) core [50319]
                1. Bacteriophage T4 [50320] (1)
          6. RNA polymerase subunit RBP8 [50321] (1)
             1. RNA polymerase subunit RBP8 [50322]
                1. Baker's yeast (Saccharomyces cerevisiae) [50323] (1)
       5. Inorganic pyrophosphatase [50324] (1)
          1. Inorganic pyrophosphatase [50325] (3)
             1. Inorganic pyrophosphatase [50326]
                1. Baker's yeast (Saccharomyces cerevisiae) [50327] (1)
                2. Escherichia coli [50329] (4)
                3. Thermus thermophilus [50330] (1)
   29. beta-Trefoil [50352] (3)
       1. Cytokine [50353] (2)
          1. Fibroblast growth factors (FGF) [50354] (2)
             1. Basic FGF (FGF2) [50355]
                1. Human (Homo sapiens) [50356] (11)
             2. Acidic FGF (FGF1) [50357]
                1. Human (Homo sapiens) [50359] (1)
          2. Interleukin-1 (IL-1) [50362] (4)
             1. Interleukin-1beta [50363]
                1. Human (Homo sapiens) [50364] (11)
                2. Mouse (Mus musculus) [50365] (2)
             2. Interleukin-1 receptor antagonist protein [50366]
                1. Human (Homo sapiens) [50367] (1)
             3. Interleukin-1alpha [50368]
                1. Human (Homo sapiens) [50369] (1)
       2. STI-like [50386] (2)
          1. Kunitz (STI) inhibitors [50387] (4)
             1. Winged bean albumin 1 [50388]
                1. Goa bean (Psophocarpus tetragonolobus) [50389] (1)
             2. Erythrina cafra trypsin inhibitor [50390]
                1. Erythrina caffra [50391] (1)
             3. chymotrypsin inhibitor WCI [50392]
                1. Winged bean (Psophocarpus tetragonolobus) [50393] (2)
             4. Soybean trypsin inhibitor [50394]
                1. Soybean (Glycine max) [50395] (1)
          2. Clostridium neurotoxins, C-terminal domain [50399] (1)
             1. Tetanus neurotoxin [50400]
                1. Clostridium tetani [50401] (2)
       3. Actin-crosslinking proteins [50405] (1)
          1. Histidine-rich actin-binding protein (hisactophilin) [50409] (1)
             1. Histidine-rich actin-binding protein (hisactophilin) [50410]
                1. Dictyostelium discoideum [50411] (2)
   30. Reductase/isomerase/elongation factor common domain [50412] (2)
       1. Riboflavin synthase domain-like [63380] (1)
          1. Ferredoxin reductase FAD-binding domain-like [63381] (7)
             1. Ferredoxin reductase (flavodoxin reductase) N-terminal domain [50415]
                1. Spinach (Spinacia oleracea) [50416] (4)
                2. Cyanobacterium (Anabaena sp.), pcc 7119 [50420] (3)
                3. Escherichia coli [50421] (1)
                4. Azotobacter vinelandii [50422] (1)
             2. Nitrate reductase core domain [50425]
                1. Corn (Zea mays) [50426] (3)
             3. cytochrome b5 reductase [50427]
                1. Pig (Sus scrofa), liver [50428] (1)
             4. Phthalate dioxygenase reductase [50430]
                1. Pseudomonas cepacia, db01 [50431] (1)
       2. Translation proteins [50447] (1)
          1. Elongation factors [50448] (2)
             1. Elongation factor Tu (EF-Tu), domain 2 [50449]
                1. Thermus aquaticus [50451] (1)
             2. Elongation factor G (EF-G), domain II [50456]
                1. Thermus thermophilus [50457] (2)
   31. Elongation factor/aminomethyltransferase common domain [50464] (1)
       1. EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain [50465] (1)
          1. EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain [50466] (1)
             1. Elongation factor Tu (EF-Tu) [50467]
                1. Thermus aquaticus [50469] (1)
   32. FMN-binding split barrel [50474] (1)
       1. FMN-binding split barrel [50475] (1)
          1. PNP-oxidase like [50476] (1)
             1. FMN-binding protein [50477]
                1. Desulfovibrio vulgaris, strain Miyazaki F [50478] (1)
   33. Trypsin-like serine proteases [50493] (1)
       1. Trypsin-like serine proteases [50494] (3)
          1. Prokaryotic proteases [50495] (5)
             1. Achromobacter protease [50496]
                1. Achromobacter lyticus, strain m497-1 [50497] (2)
             2. alpha-Lytic protease [50498]
                1. Lysobacter enzymogenes, 495 [50499] (3)
             3. Protease A [50500]
                1. Streptomyces griseus, strain k1 [50501] (2)
             4. Trypsin [50504]
                1. Streptomyces griseus, strain k1 [50505] (1)
             5. Serine proteinase [50506]
                1. Streptomyces fradiae [50507] (1)
          2. Eukaryotic proteases [50514] (11)
             1. Trypsin(ogen) [50515]
                1. Cow (Bos taurus) [50516] (43)
                2. Rat (Rattus norvegicus) [50518] (7)
                3. North atlantic salmon (Salmo salar) [50520] (2)
                4. Mold (Fusarium oxysporum) [50521] (1)
             2. (alpha,gamma)-chymotrypsin(ogen) [50522]
                1. Cow (Bos taurus) [50523] (23)
             3. Elastase [50536]
                1. Pig (Sus scrofa) [50538] (15)
                2. Salmon (Salmo salar) [50539] (1)
             4. Heparin binding protein, HBP [50544]
                1. Human (Homo sapiens) [50545] (2)
             5. Chymase II (mast cell proteinase II) [50552]
                1. Human (Homo sapiens) [50554] (1)
             6. Tonin [50557]
                1. Rat (Rattus rattus) [50558] (1)
             7. Factor D [50563]
                1. Human (Homo sapiens) [50564] (3)
          3. Viral proteases [50596] (2)
             1. Viral capsid protein [50597]
                1. Sindbis virus [50598] (7)
             2. NS3 protease [50600]
                1. Human hepatitis C virus (HCV), different isolates [50601] (1)
   34. mu transposase, C-terminal domain [50609] (1)
       1. mu transposase, C-terminal domain [50610] (1)
          1. mu transposase, C-terminal domain [50611] (1)
             1. mu transposase, C-terminal domain [50612]
                1. Bacteriophage mu [50613] (1)
   35. Domain of alpha and beta subunits of F1 ATP synthase-like [50614] (1)
       1. Alanine racemase C-terminal domain-like [50621] (1)
          1. Alanine racemase [88682] (1)
             1. Alanine racemase [50623]
                1. Streptomyces lavendulae [110244] (1)
   36. Acid proteases [50629] (1)
       1. Acid proteases [50630] (2)
          1. Retroviral protease (retropepsin) [50631] (4)
             1. Human immunodeficiency virus type 1 protease [50632]
                1. Human immunodeficiency virus type 1 [50633] (6)
             2. Simian immunodeficiency virus (SIV) protease [50636]
                1. Simian immunodeficiency virus, different strains [50637] (3)
             3. Feline immunodeficiency virus (FIV) protease [50638]
                1. Feline immunodeficiency virus [50639] (1)
             4. EIAV protease [50644]
                1. Equine infectious anemia virus [50645] (2)
          2. Pepsin-like [50646] (11)
             1. Endothiapepsin [50647]
                1. Chestnut blight fungus (Endothia parasitica) [50648] (1)
             2. Acid protease [50649]
                1. Fungus (Penicillium janthinellum), penicillopepsin [50650] (5)
                2. Bread mold (Rhizopus chinensis) [50651] (1)
                3. Rhizomucor miehei [50652] (1)
                4. Yeast (Candida albicans) [50653] (1)
             3. Pepsin(ogen) [50658]
                1. Pig (Sus scrofa) [50659] (5)
                2. Human (Homo sapiens), 3A [50660] (1)
                3. Atlantic cod (Gadus morhua) [50662] (1)
             4. Pepsin [50663]
                1. Mucor pusillus [50664] (1)
             5. Chymosin (synonym: renin) [50667]
                1. Cow (Bos taurus) [50668] (3)
                2. Human (Homo sapiens) [50669] (3)
   37. ValRS/IleRS/LeuRS editing domain [50676] (1)
       1. ValRS/IleRS/LeuRS editing domain [50677] (1)
          1. ValRS/IleRS/LeuRS editing domain [50678] (1)
             1. Isoleucyl-tRNA synthetase (IleRS) [50679]
                1. Thermus thermophilus [50680] (1)
   38. Double psi beta-barrel [50684] (2)
       1. Barwin-like endoglucanases [50685] (2)
          1. Endoglucanase V (Eng V) [50686] (1)
             1. Endoglucanase V (Eng V) [50687]
                1. Humicola insolens [50688] (3)
          2. Barwin [50689] (1)
             1. Barwin [50690]
                1. Barley (Hordeum vulgare) [50691] (2)
       2. ADC-like [50692] (1)
          1. Formate dehydrogenase/DMSO reductase, C-terminal domain [50696] (3)
             1. Dimethylsulfoxide reductase (DMSO reductase) [50697]
                1. Rhodobacter capsulatus [50699] (5)
             2. Formate dehydrogenase H [50700]
                1. Escherichia coli [50701] (3)
             3. Trimethylamine N-oxide reductase [50702]
                1. Shewanella massilia [50703] (1)
   39. PH domain-like [50728] (1)
       1. PH domain-like [50729] (1)
          1. Pleckstrin-homology domain (PH domain) [50730] (7)
             1. Phospholipase C delta-1 [50731]
                1. Rat (Rattus norvegicus) [50732] (1)
             2. beta-spectrin [50733]
                1. Mouse (Mus musculus), brain [50734] (2)
                2. Fruit fly (Drosophila melanogaster) [50735] (1)
             3. Pleckstrin, N-terminal domain [50740]
                1. Human (Homo sapiens) [50741] (1)
             4. Son of sevenless-1 (sos-1) [50742]
                1. Mouse (Mus musculus) [50743] (1)
                2. Human (Homo sapiens) [50744] (1)
             5. G-protein coupled receptor kinase 2 (beta-adrenergic receptor kinase 1) [50747]
                1. Human (Homo sapiens) [50748] (1)
   40. Herpes virus serine proteinase, assemblin [50788] (1)
       1. Herpes virus serine proteinase, assemblin [50789] (1)
          1. Herpes virus serine proteinase, assemblin [50790] (2)
             1. Human cytomegalovirus protease [50791]
                1. Human cytomegalovirus [50792] (1)
             2. VZV protease [50797]
                1. Varicella-Zoster virus [50798] (1)
   41. PK beta-barrel domain-like [50799] (1)
       1. PK beta-barrel domain-like [50800] (1)
          1. Pyruvate kinase beta-barrel domain [50801] (2)
             1. Pyruvate kinase (PK) [50802]
                1. Rabbit (Oryctolagus cuniculus) [50803] (1)
                2. Cat (Felis catus) [50804] (1)
   42. Lipocalins [50813] (1)
       1. Lipocalins [50814] (2)
          1. Retinol binding protein-like [50815] (6)
             1. Retinol binding protein [50816]
                1. Cow (Bos taurus) [50817] (6)
                2. Pig (Sus scrofa domestica) [50818] (1)
                3. Human (Homo sapiens) [50819] (3)
             2. Lipocalin allergen [50824]
                1. Cow (Bos taurus), bos d 2 [50825] (1)
             3. beta-Lactoglobulin [50827]
                1. Cow (Bos taurus) [50828] (4)
             4. Major urinary protein/alpha-2u-globulin [50832]
                1. Mouse (Mus musculus) [50833] (1)
          2. Fatty acid binding protein-like [50847] (9)
             1. Muscle fatty acid binding protein (m-fabp) [50848]
                1. Human (Homo sapiens) [50849] (4)
             2. Intestinal fatty acid binding protein [50851]
                1. Rat (Rattus norvegicus) [50852] (8)
             3. Epidermal fatty acid binding protein [50854]
                1. Human (Homo sapiens) [50855] (1)
             4. Adipocyte lipid-binding protein, ALBP [50856]
                1. Mouse (Mus musculus) [50857] (10)
             5. Fatty acid-binding protein [50858]
                1. Tobacco hornworm (Manduca sexta) [50859] (1)
             6. Cellular retinoic-acid-binding protein (CRABP) [50861]
                1. Human (Homo sapiens), CRABP-II [50862] (4)
             7. Cellular retinol-binding protein II (CRBP) [50864]
                1. Rat (Rattus norvegicus) [50865] (2)
             8. Liver fatty acid binding protein [50866]
                1. Rat (Rattus norvegicus) [50867] (1)
             9. Ileal lipid-binding protein [50870]
                1. Pig (Sus scrofa) [50871] (1)
   43. Streptavidin-like [50875] (1)
       1. Avidin/streptavidin [50876] (1)
          1. Avidin/streptavidin [50877] (1)
             1. Streptavidin [50878]
                1. Streptomyces avidinii [50879] (11)
   44. Cyclophilin-like [50890] (1)
       1. Cyclophilin-like [50891] (1)
          1. Cyclophilin (peptidylprolyl isomerase) [50892] (3)
             1. Cyclophilin (eukaryotic) [50893]
                1. Human (Homo sapiens), variant A [50894] (2)
                2. Nematode (Brugia malayi) [50898] (2)
             2. Peptidyl-prolyl cis-trans isomerase A, PpiA [50901]
                1. Escherichia coli [50902] (2)
   45. Oncogene products [50903] (1)
       1. Oncogene products [50904] (1)
          1. Oncogene products [50905] (2)
             1. p14-TCL1 [50906]
                1. Human (Homo sapiens) [50907] (1)
             2. p13-MTCP1 [50908]
                1. Human (Homo sapiens) [50909] (1)
   46. 4-bladed beta-propeller [50922] (1)
       1. Hemopexin-like domain [50923] (1)
          1. Hemopexin-like domain [50924] (4)
             1. Hemopexin [50925]
                1. Rabbit (Oryctolagus cuniculus) [50926] (1)
             2. Gelatinase A (MMP-2), C-terminal domain [50927]
                1. Human (Homo sapiens) [50928] (2)
             3. Collagenase (MMP1), C-terminal domain [50929]
                1. Pig (Sus scrofa) [50930] (1)
             4. Collagenase-3 (MMP-13), C-terminal domain [50931]
                1. Human (Homo sapiens) [50932] (1)
   47. 6-bladed beta-propeller [50938] (1)
       1. Sialidases [50939] (1)
          1. Sialidases (neuraminidases) [50940] (6)
             1. Salmonella sialidase [50941]
                1. Salmonella typhimurium, strain lt2 [50942] (5)
             2. Influenza neuraminidase [50943]
                1. Influenza A virus, different strains [50944] (31)
                2. Influenza B virus, different strains [50945] (3)
             3. Micromonospora sialidase, N-terminal domain [50946]
                1. Micromonospora viridifaciens [50947] (4)
             4. Leech intramolecular trans-sialidase, C-terminal domain [50948]
                1. North american leech (Macrobdella decora) [50949] (5)
             5. Vibrio cholerae sialidase [50950]
                1. Vibrio cholerae [50951] (1)
   48. 7-bladed beta-propeller [50964] (1)
       1. Galactose oxidase, central domain [50965] (1)
          1. Galactose oxidase, central domain [50966] (1)
             1. Galactose oxidase, central domain [50967]
                1. Dactylium dendroides [50968] (3)
   49. Glycosyl hydrolase domain [51010] (1)
       1. Glycosyl hydrolase domain [51011] (1)
          1. alpha-Amylases, C-terminal beta-sheet domain [51012] (15)
             1. Bacterial alpha-Amylase [51013]
                1. Bacillus licheniformis [51014] (2)
                2. Pseudoalteromonas haloplanctis (Alteromonas haloplanctis) [51015] (2)
                3. Bacillus subtilis [51016] (1)
             2. Cyclodextrin glycosyltransferase [51018]
                1. Bacillus circulans, different strains [51019] (18)
                2. Bacillus stearothermophilus [51020] (1)
                3. Thermoanaerobacterium thermosulfurigenes, EM1 [51023] (2)
             3. Animal alpha-amylase [51024]
                1. Pig (Sus scrofa) [51025] (5)
                2. Human (Homo sapiens) [51026] (3)
                3. Yellow mealworm (Tenebrio molitor), larva [51027] (1)
             4. Fungal alpha-amylase [51028]
                1. Aspergillus niger, acid amylase [51029] (1)
                2. Aspergillus oryzae, Taka-amylase [51030] (2)
             5. Isoamylase [51036]
                1. Pseudomonas amyloderamosa [51037] (1)
             6. G4-amylase (1,4-alpha-D-glucan maltotetrahydrolase) [51038]
                1. Pseudomonas stutzeri [51039] (4)
             7. Plant alpha-amylase [51040]
                1. Barley (Hordeum vulgare), seeds, AMY2 isozyme [51041] (2)
             8. Oligo-1,6-glucosidase [51042]
                1. Bacillus cereus [51043] (1)
   50. WW domain-like [51044] (1)
       1. Carbohydrate binding domain [51055] (1)
          1. Carbohydrate binding domain [51056] (1)
             1. Cellulose-binding domain of endoglucanase Z [51057]
                1. Erwinia chrysanthemi [51058] (1)
   51. Carbonic anhydrase [51068] (1)
       1. Carbonic anhydrase [51069] (1)
          1. Carbonic anhydrase [51070] (4)
             1. Carbonic anhydrase [51071]
                1. Human (Homo sapiens), erythrocytes, isozyme I [51072] (7)
                2. Human (Homo sapiens), erythrocytes, isozyme II [51073] (105)
                3. Mouse (Mus musculus), isozyme IV [51077] (2)
                4. Mouse (Mus musculus), liver, isozyme V [51078] (1)
   52. Bacteriochlorophyll A protein [51080] (1)
       1. Bacteriochlorophyll A protein [51081] (1)
          1. Bacteriochlorophyll A protein [51082] (1)
             1. Bacteriochlorophyll A protein [51083]
                1. Prosthecochloris aestuarii, strain 2k [51084] (1)
   53. beta-Prism I [51091] (1)
       1. delta-Endotoxin (insectocide), middle domain [51096] (1)
          1. delta-Endotoxin (insectocide), middle domain [51097] (2)
             1. delta-Endotoxin (insectocide), middle domain [51098]
                1. Bacillus thuringiensis tenebrionis, CRYIIIA (BT13) [51099] (1)
                2. Bacillus thuringiensis, CRYIA (A) [51100] (1)
   54. beta-Prism II [51109] (1)
       1. alpha-D-mannose-specific plant lectins [51110] (1)
          1. alpha-D-mannose-specific plant lectins [51111] (1)
             1. Lectin (agglutinin) [51112]
                1. Snowdrop (Galanthus nivalis) [51113] (1)
   55. Single-stranded right-handed beta-helix [51125] (2)
       1. beta-Roll [51120] (1)
          1. Serralysin-like metalloprotease, C-terminal domain [51121] (2)
             1. Metalloprotease [51122]
                1. Pseudomonas aeruginosa [51123] (1)
                2. Serratia marcescens [51124] (2)
       2. Pectin lyase-like [51126] (4)
          1. Pectate lyase-like [51127] (2)
             1. Pectate lyase [51128]
                1. Erwinia chrysanthemi, type C [51129] (2)
                2. Erwinia chrysanthemi, type E [51130] (1)
          2. Pectin lyase [51133] (1)
             1. Pectin lyase [51134]
                1. Aspergillus niger, type A [51135] (1)
          3. Galacturonase [51137] (2)
             1. Rhamnogalacturonase A [51138]
                1. Aspergillus aculeatus [51139] (1)
             2. Polygalacturonase [51140]
                1. Erwinia carotovora, subsp. carotovora [51141] (1)
          4. P22 tailspike protein [51150] (1)
             1. P22 tailspike protein [51151]
                1. Salmonella phage P22 [51152] (5)
   56. Single-stranded left-handed beta-helix [51160] (1)
       1. Trimeric LpxA-like enzymes [51161] (3)
          1. UDP N-acetylglucosamine acyltransferase [51162] (1)
             1. UDP N-acetylglucosamine acyltransferase [51163]
                1. Escherichia coli, gene lpxA [51164] (1)
          2. Tetrahydrodipicolinate-N-succinlytransferase, THDP-succinlytransferase, DapD [51165] (1)
             1. Tetrahydrodipicolinate-N-succinlytransferase, THDP-succinlytransferase, DapD [51166]
                1. Mycobacterium bovis [51167] (2)
          3. Galactoside acetyltransferase-like [51168] (1)
             1. Xenobiotic acetyltransferase [51169]
                1. Pseudomonas aeruginosa [51170] (2)
   57. Double-stranded beta-helix [51181] (4)
       1. RmlC-like cupins [51182] (2)
          1. Germin/Seed storage 7S protein [51187] (1)
             1. Seed storage 7S protein [51188]
                1. French bean (Phaseolus vulgaris), phaseolin [51189] (2)
          2. Type I phosphomannose isomerase [51191] (1)
             1. Phosphomannose isomerase [51192]
                1. Yeast (Candida albicans) [51193] (1)
       2. Clavaminate synthase-like [51197] (1)
          1. Penicillin synthase-like [51198] (2)
             1. Isopenicillin N synthase [51199]
                1. Emericella nidulans [51200] (2)
             2. Deacetoxycephalosporin C synthase [51201]
                1. Streptomyces clavuligerus [51202] (3)
       3. cAMP-binding domain-like [51206] (1)
          1. cAMP-binding domain [51210] (1)
             1. Regulatory subunit of Protein kinase A [51213]
                1. Cow (Bos taurus) [51214] (2)
       4. Regulatory protein AraC [51215] (1)
          1. Regulatory protein AraC [51216] (1)
             1. Regulatory protein AraC [51217]
                1. Escherichia coli [51218] (1)
   58. Barrel-sandwich hybrid [51229] (3)
       1. Single hybrid motif [51230] (1)
          1. Biotinyl/lipoyl-carrier proteins and domains [51231] (7)
             1. Biotinyl domain of acetyl-CoA carboxylase [51232]
                1. Escherichia coli [51233] (2)
             2. Protein H of glycine cleavage system [51236]
                1. Pea (Pisum sativum) [51237] (1)
             3. Lipoyl domain of dihydrolipoamide acetyltransferase [51238]
                1. Bacillus stearothermophilus [51239] (2)
                2. Azotobacter vinelandii [51240] (2)
                3. Human (Homo sapiens) [51242] (1)
             4. Lipoyl domain of the 2-oxoglutarate dehydrogenase complex [51243]
                1. Azotobacter vinelandii [51244] (2)
                2. Escherichia coli [51245] (1)
       2. Rudiment single hybrid motif [51246] (1)
          1. Cytochrome f, small domain [51256] (1)
             1. Cytochrome f, small domain [51257]
                1. Turnip (Brassica rapa) [51258] (2)
       3. Duplicated hybrid motif [51261] (1)
          1. Glucose permease-like [51262] (3)
             1. Glucose permease IIa domain, IIa-glc [51263]
                1. Bacillus subtilis [51264] (2)
                2. Mycoplasma capricolum [51265] (1)
             2. Glucose-specific factor III (glsIII) [51266]
                1. Escherichia coli [51267] (2)
   59. beta-clip [51268] (4)
       1. AFP III-like domain [51269] (1)
          1. AFP III-like domain [51270] (2)
             1. Type III antifreeze protein, AFP III [51271]
                1. Ocean pout (Macrozoarces americanus), different isoforms [51272] (12)
                2. Antarctic eel pout (Austrolycichthys brachycephalus) and (Lycodichthys dearborni), RD3 isoform [51273] (2)
       2. SET domain [82199] (1)
          1. Histone lysine methyltransferases [82200] (1)
             1. Histone H3 K4-specific methyltransferase SET7/9 catalytic domain [82205]
                1. Human (Homo sapiens) [82206] (2)
       3. dUTPase-like [51283] (1)
          1. dUTPase-like [51284] (2)
             1. Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) [51285]
                1. Escherichia coli [51286] (1)
                2. Equine infectious anemia virus [51288] (2)
       4. Tlp20, baculovirus telokin-like protein [51289] (1)
          1. Tlp20, baculovirus telokin-like protein [51290] (1)
             1. Tlp20, baculovirus telokin-like protein [51291]
                1. AcMNPV (Autographa californica nuclear polyhedrosis virus) [51292] (1)
   60. Hedgehog/intein (Hint) domain [51293] (1)
       1. Hedgehog/intein (Hint) domain [51294] (2)
          1. Hedgehog C-terminal (Hog) autoprocessing domain [51295] (1)
             1. Hedgehog [51296]
                1. Fruit fly (Drosophila melanogaster) [51297] (1)
          2. Intein (protein splicing domain) [51298] (1)
             1. GyrA intein [51303]
                1. Mycobacterium xenopi [51304] (1)
   61. Cyanovirin-N [51321] (1)
       1. Cyanovirin-N [51322] (1)
          1. Cyanovirin-N [51323] (1)
             1. Cyanovirin-N [51324]
                1. Cyanobacterium (Nostoc ellipsosporum) [51325] (2)
   62. Epsilon subunit of F1F0-ATP synthase N-terminal domain [51343] (1)
       1. Epsilon subunit of F1F0-ATP synthase N-terminal domain [51344] (1)
          1. Epsilon subunit of F1F0-ATP synthase N-terminal domain [51345] (1)
             1. Epsilon subunit of F1F0-ATP synthase N-terminal domain [51346]
                1. Escherichia coli [51347] (1)
3. Alpha and beta proteins (a/b) [51349] (71)
   Mainly parallel beta sheets (beta-alpha-beta units)
   1. TIM beta/alpha-barrel [51350] (16)
      1. Triosephosphate isomerase (TIM) [51351] (1)
         1. Triosephosphate isomerase (TIM) [51352] (2)
            1. Triosephosphate isomerase [51353]
               1. Trypanosoma brucei [51357] (4)
               2. Leishmania mexicana [51360] (1)
      2. Ribulose-phoshate binding barrel [51366] (1)
         1. Tryptophan biosynthesis enzymes [51381] (4)
            1. N-(5'phosphoribosyl)antranilate isomerase, PRAI [51382]
               1. Escherichia coli [51383] (1)
               2. Thermotoga maritima [51384] (1)
            2. Indole-3-glycerophosphate synthase, IPGS [51385]
               1. Escherichia coli [51386] (1)
               2. Archaeon Sulfolobus solfataricus [51387] (4)
      3. FMN-linked oxidoreductases [51395] (1)
         1. FMN-linked oxidoreductases [51396] (2)
            1. Old yellow enzyme (OYE) [51401]
               1. Brewer's yeast (Saccharomyces carlsbergensis) [51402] (3)
            2. Glycolate oxidase [51404]
               1. Spinach (Spinacia oleracea) [51405] (3)
      4. Inosine monophosphate dehydrogenase (IMPDH) [51412] (1)
         1. Inosine monophosphate dehydrogenase (IMPDH) [51413] (1)
            1. Inosine monophosphate dehydrogenase (IMPDH) [51414]
               1. Tritrichomonas foetus [51417] (1)
      5. PLP-binding barrel [51419] (1)
         1. "Hypothetical" protein ybl036c [51427] (1)
            1. "Hypothetical" protein ybl036c [51428]
               1. Baker's yeast (Saccharomyces cerevisiae) [51429] (1)
      6. NAD(P)-linked oxidoreductase [51430] (1)
         1. Aldo-keto reductases (NADP) [51431] (5)
            1. FR-1 (fibroblast growth factor-induced) protein [51432]
               1. Mouse (Mus musculus) [51433] (1)
            2. Aldose reductase (aldehyde reductase) [51436]
               1. Human (Homo sapiens) [51437] (10)
               2. Pig (Sus scrofa) [51438] (5)
            3. 3-alpha-hydroxysteroid dehydrogenase [51439]
               1. Rat (Rattus norvegicus) [51440] (1)
            4. 2,5-diketo-D-gluconic acid reductase A [51443]
               1. Corynebacterium sp. [51444] (1)
      7. (Trans)glycosidases [51445] (5)
         1. Amylase, catalytic domain [51446] (16)
            1. Bacterial alpha-amylase [51447]
               1. Bacillus licheniformis [51448] (2)
               2. Pseudoalteromonas haloplanctis (Alteromonas haloplanctis) [51449] (2)
               3. Bacillus subtilis [51450] (1)
            2. Cyclodextrin glycosyltransferase [51452]
               1. Bacillus circulans, different strains [51453] (18)
               2. Bacillus stearothermophilus [51454] (1)
               3. Thermoanaerobacterium thermosulfurigenes, EM1 [51457] (2)
            3. Animal alpha-amylase [51458]
               1. Pig (Sus scrofa) [51459] (5)
               2. Human (Homo sapiens) [51460] (3)
               3. Yellow mealworm (Tenebrio molitor), larva [51461] (1)
            4. Fungal alpha-amylases [51462]
               1. Aspergillus niger, acid amylase [51463] (1)
               2. Aspergillus oryzae, Taka-amylase [51464] (2)
            5. Isoamylase, central domain [51470]
               1. Pseudomonas amyloderamosa [51471] (1)
            6. G4-amylase (1,4-alpha-D-glucan maltotetrahydrolase) [51472]
               1. Pseudomonas stutzeri [51473] (4)
            7. Plant alpha-amylase [51474]
               1. Barley (Hordeum vulgare), seeds, AMY2 isozyme [51475] (2)
            8. Oligo-1,6, glucosidase [51476]
               1. Bacillus cereus [51477] (1)
            9. beta-Amylase [51481]
               1. Soybean (Glycine max) [51482] (6)
         2. beta-glycanases [51487] (9)
            1. Xylanase [51488]
               1. Penicillium simplicissimum [51490] (1)
            2. Endoglucanase CelA [51491]
               1. Clostridium cellulolyticum [51492] (1)
            3. Endoglucanase CelC [51493]
               1. Clostridium thermocellum [51494] (3)
            4. Endoglucanase Cel5a [51499]
               1. Bacillus agaradhaerens [51500] (3)
            5. Plant beta-glucanases [51507]
               1. Barley (Hordeum vulgare), 1,3-1,4-beta-glucanase [51509] (1)
            6. Xylanase A, catalytic core [51514]
               1. Streptomyces lividans [51515] (1)
               2. Pseudomonas fluorescens [51517] (1)
               3. Thermoascus aurantiacus [51518] (1)
               4. Cellulomonas fimi [51520] (4)
         3. Family 1 of glycosyl hydrolase [51521] (3)
            1. Plant beta-glucosidase (myrosinase) [51522]
               1. White mustard (Sinapis alba) [51523] (1)
               2. Creeping white clover (Trifolium repens) [51524] (1)
            2. 6-phospho-beta-D-galactosidase, PGAL [51526]
               1. Lactococcus lactis [51527] (1)
         4. Type II chitinase [51534] (6)
            1. Hevamine A (chitinase/lysozyme) [51535]
               1. Para rubber tree (Hevea brasiliensis) [51536] (3)
            2. Seed storage protein [51537]
               1. Vicia narbonensis, Narbonin [51538] (1)
               2. Jack bean (Canavalia ensiformis), Concanavalin B [51539] (1)
            3. Endo-beta-N-acetylglucosaminidase [51540]
               1. Flavobacterium meningosepticum, endoglycosidase F1 [51541] (1)
               2. Streptomyces plicatus, endoglycosidase H [51543] (1)
            4. Chitinase A, catalytic domain [51544]
               1. Serratia marcescens [51545] (1)
         5. beta-N-acetylhexosaminidase catalytic domain [51550] (1)
            1. Bacterial chitobiase (beta-N-acetylhexosaminidase) [51551]
               1. Serratia marcescens [51552] (2)
      8. Metallo-dependent hydrolases [51556] (2)
         1. Adenosine deaminase (ADA) [51557] (1)
            1. Adenosine deaminase (ADA) [51558]
               1. Mouse (Mus musculus) [51559] (6)
         2. Phosphotriesterase-like [51564] (1)
            1. Phosphotriesterase (parathion hydrolase, PTE) [51565]
               1. Pseudomonas diminuta [51566] (1)
      9. Aldolase [51569] (3)
         1. Class I aldolase [51570] (1)
            1. Fructose-1,6-bisphosphate aldolase [51576]
               1. Human (Homo sapiens), muscle isozyme [51577] (2)
         2. Class II FBP aldolase [51591] (1)
            1. Fructose-bisphosphate aldolase (FBP aldolase) [51592]
               1. Escherichia coli [51593] (1)
         3. 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51594] (1)
            1. 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51595]
               1. Baker's yeast (Saccharomyces cerevisiae) [51596] (1)
      10. Enolase C-terminal domain-like [51604] (2)
          1. Enolase [51605] (2)
             1. Enolase [51606]
                1. Baker's yeast (Saccharomyces cerevisiae) [51607] (7)
                2. Lobster (Homarus vulgaris) [51608] (2)
          2. D-glucarate dehydratase-like [51609] (3)
             1. D-glucarate dehydratase [51610]
                1. Pseudomonas putida [51611] (1)
             2. Mandelate racemase [51617]
                1. Pseudomonas putida [51618] (6)
             3. Chlormuconate cycloisomerase [51619]
                1. Alcaligenes eutrophus [51620] (1)
      11. Phosphoenolpyruvate/pyruvate domain [51621] (3)
          1. Pyruvate kinase [51622] (2)
             1. Pyruvate kinase, N-terminal domain [51623]
                1. Cat (Felis catus) [51624] (1)
                2. Rabbit (Oryctolagus cuniculus) [51625] (1)
          2. Pyruvate phosphate dikinase, C-terminal domain [51629] (1)
             1. Pyruvate phosphate dikinase, C-terminal domain [51630]
                1. Clostridium symbiosum [51631] (1)
          3. Phosphoenolpyruvate carboxylase [51632] (1)
             1. Phosphoenolpyruvate carboxylase [51633]
                1. Escherichia coli [51634] (1)
      12. Xylose isomerase-like [51658] (1)
          1. Xylose isomerase [51665] (2)
             1. D-xylose isomerase [51666]
                1. Streptomyces albus [51667] (1)
                2. Streptomyces rubiginosus [51670] (15)
      13. Bacterial luciferase-like [51679] (1)
          1. Non-fluorescent flavoprotein (luxF, FP390) [51683] (1)
             1. Non-fluorescent flavoprotein (luxF, FP390) [51684]
                1. Photobacterium leiognathi [51685] (1)
      14. PLC-like phosphodiesterases [51695] (1)
          1. Bacterial PLC [51699] (2)
             1. Phosphatidylinositol-specific phospholipase C [51700]
                1. Bacillus cereus [51701] (9)
                2. Listeria monocytogenes [51702] (2)
      15. tRNA-guanine transglycosylase [51713] (1)
          1. tRNA-guanine transglycosylase [51714] (1)
             1. Queosine tRNA-guanine transglycosylase [51715]
                1. Zymomonas mobilis [51716] (4)
      16. Dihydropteroate synthetase-like [51717] (1)
          1. Dihydropteroate synthetase [51718] (1)
             1. Dihydropteroate synthetase [51719]
                1. Escherichia coli [51720] (3)
   2. NAD(P)-binding Rossmann-fold domains [51734] (1)
      1. NAD(P)-binding Rossmann-fold domains [51735] (7)
         1. Alcohol dehydrogenase-like, C-terminal domain [51736] (1)
            1. Alcohol dehydrogenase [51737]
               1. Horse (Equus caballus) [51738] (6)
         2. Tyrosine-dependent oxidoreductases [51751] (9)
            1. Uridine diphosphogalactose-4-epimerase (UDP-galactose 4-epimerase) [51752]
               1. Escherichia coli [51753] (13)
            2. Sepiapterin reductase [51767]
               1. Mouse (Mus musculus) [51768] (3)
            3. Dihydropteridin reductase (pteridine reductase) [51769]
               1. Rat (Rattus norvegicus) [51770] (1)
               2. Human (Homo sapiens) [51771] (1)
            4. Human estrogenic 17beta-hydroxysteroid dehydrogenase [51772]
               1. Human (Homo sapiens) [51773] (6)
            5. Cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase [51780]
               1. Pseudomonas sp., lb400 [51781] (1)
            6. Enoyl-ACP reductase [51791]
               1. Oil seed rape (Brassica napus) [51792] (2)
               2. Mycobacterium tuberculosis, TB, gene InhA [51793] (3)
            7. Tropinone reductase [51795]
               1. Jimsonweed (Datura stramonium), II [51797] (1)
         3. Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (5)
            1. Diaminopimelic acid dehydrogenase (DAPDH) [51819]
               1. Corynebacterium glutamicum [51820] (1)
            2. Dihydrodipicolinate reductase [51821]
               1. Escherichia coli [51822] (4)
               2. Thermotoga maritima [110417] (2)
            3. Glucose 6-phosphate dehydrogenase, N-terminal domain [51827]
               1. Leuconostoc mesenteroides [51828] (1)
            4. Virulence factor MviM [110421]
               1. Escherichia coli [110422] (2)
         4. Formate/glycerate dehydrogenases, NAD-domain [51830] (1)
            1. D-2-hydroxyisocaproate dehydrogenase [51835]
               1. Lactobacillus casei [51836] (1)
         5. LDH N-terminal domain-like [51848] (8)
            1. Malate dehydrogenase [51849]
               1. Escherichia coli [51853] (2)
            2. Lactate dehydrogenase [51859]
               1. Pig (Sus scrofa) [51860] (1)
               2. Mouse (Mus musculus) [51861] (1)
               3. Dogfish (Squalus acanthias) [51862] (3)
               4. Malaria parasite (Plasmodium falciparum) [51863] (1)
               5. Bacillus stearothermophilus [51864] (2)
               6. Lactobacillus casei [51865] (1)
               7. Thermotoga maritima [51867] (1)
         6. 6-phosphogluconate dehydrogenase-like, N-terminal domain [51868] (2)
            1. 6-phosphogluconate dehydrogenase [51871]
               1. Sheep (Ovis orientalis aries) [51872] (5)
            2. N-(1-D-carboxylethyl)-L-norvaline dehydrogenase [51879]
               1. Arthrobacter, strain 1c [51880] (1)
         7. Aminoacid dehydrogenase-like, C-terminal domain [51883] (1)
            1. Glutamate dehydrogenase [51884]
               1. Clostridium symbiosum [51885] (2)
   3. FAD/NAD(P)-binding domain [51904] (1)
      1. FAD/NAD(P)-binding domain [51905] (3)
         1. FAD-linked reductases, N-terminal domain [51913] (4)
            1. Cholesterol oxidase of GMC family [51914]
               1. Brevibacterium sterolicum [51915] (2)
            2. Glucose oxidase [51924]
               1. Aspergillus niger [51925] (1)
            3. p-Hydroxybenzoate hydroxylase, PHBH [51917]
               1. Pseudomonas fluorescens [51918] (11)
               2. Pseudomonas aeruginosa [51919] (13)
         2. GDI-like N domain [51931] (1)
            1. Guanine nucleotide dissociation inhibitor, GDI [51932]
               1. Cow (Bos taurus) [51933] (1)
         3. FAD/NAD-linked reductases, N-terminal and central domains [51943] (6)
            1. Glutathione reductase [51944]
               1. Human (Homo sapiens) [51945] (30)
            2. Thioredoxin reductase [51950]
               1. Escherichia coli [51951] (6)
               2. Mouse-ear cress (Arabidopsis thaliana) [51952] (2)
            3. NADH peroxidase [51955]
               1. Enterococcus faecalis [51956] (14)
            4. Dihydrolipoamide dehydrogenase [51959]
               1. Pseudomonas putida [51960] (2)
               2. Neisseria meningitidis [51964] (4)
   4. MurCD N-terminal domain [51983] (1)
      1. MurCD N-terminal domain [51984] (1)
         1. MurCD N-terminal domain [51985] (1)
            1. UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase MurD [51986]
               1. Escherichia coli [51987] (1)
   5. 7-stranded beta/alpha barrel [51988] (1)
      1. Glycosyl hydrolases family 6, cellulases [51989] (1)
         1. Glycosyl hydrolases family 6, cellulases [51990] (2)
            1. Cellulase E2 [51991]
               1. Thermomonospora fusca, strain yx [51992] (1)
            2. Cellobiohydrolase II (Cel6) [51993]
               1. Trichoderma reesei, Cel6a [51994] (1)
   6. PFL-like glycyl radical enzymes [51997] (1)
      1. PFL-like glycyl radical enzymes [51998] (1)
         1. R1 subunit of ribonucleotide reductase, C-terminal domain [52002] (1)
            1. R1 subunit of ribonucleotide reductase, C-terminal domain [52003]
               1. Escherichia coli [52004] (1)
   7. The "swivelling" beta/beta/alpha domain [52008] (3)
      1. Phosphohistidine domain [52009] (2)
         1. Pyruvate phosphate dikinase, central domain [52010] (1)
            1. Pyruvate phosphate dikinase, central domain [52011]
               1. Clostridium symbiosum [52012] (1)
         2. N-terminal domain of enzyme I of the PEP:sugar phosphotransferase system [52013] (1)
            1. N-terminal domain of enzyme I of the PEP:sugar phosphotransferase system [52014]
               1. Escherichia coli [52015] (7)
      2. LeuD-like [52016] (1)
         1. LeuD-like [52017] (2)
            1. Aconitase A, C-terminal domain [52018]
               1. Pig (Sus scrofa) [52019] (3)
               2. Cow (Bos taurus) [52020] (7)
      3. GroEL apical domain-like [52029] (2)
         1. GroEL-like chaperone, apical domain [52030] (1)
            1. GroEL, A domain [52031]
               1. Escherichia coli [52032] (3)
         2. Group II chaperonin (CCT, TRIC), apical domain [52034] (1)
            1. Thermosome, A-domain [52035]
               1. Archaeon Thermoplasma acidophilum, alpha chain [100946] (2)
   8. Barstar-like [52037] (1)
      1. Barstar (barnase inhibitor) [52038] (1)
         1. Barstar (barnase inhibitor) [52039] (1)
            1. Barstar (barnase inhibitor) [52040]
               1. Bacillus amyloliquefaciens [52041] (3)
   9. Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) [52046] (1)
      1. RNI-like [52047] (1)
         1. 28-residue LRR [52048] (1)
            1. Ribonuclease inhibitor [52049]
               1. Pig (Sus scrofa) [52050] (1)
   10. SpoIIaa-like [52086] (2)
       1. CRAL/TRIO domain [52087] (1)
          1. CRAL/TRIO domain [52088] (1)
             1. C-terminal domain of phosphatidylinositol transfer protein sec14p [52089]
                1. Baker's yeast (Saccharomyces cerevisiae) [52090] (1)
       2. Anti-sigma factor antagonist SpoIIaa [52091] (1)
          1. Anti-sigma factor antagonist SpoIIaa [52092] (1)
             1. Anti-sigma factor antagonist SpoIIaa [52093]
                1. Bacillus subtilis [52094] (2)
   11. ClpP/crotonase [52095] (1)
       1. ClpP/crotonase [52096] (1)
          1. Biotin dependent carboxylase carboxyltransferase domain [89572] (1)
             1. Glutaconyl-CoA decarboxylase A subunit [102210]
                1. Acidaminococcus fermentans [102211] (2)
   12. DNA glycosylase [52140] (1)
       1. DNA glycosylase [52141] (1)
          1. Uracil-DNA glycosylase [52142] (2)
             1. Uracil-DNA glycosylase [52143]
                1. Human (Homo sapiens) [52144] (1)
                2. Herpes simplex virus type 1 [52145] (2)
   13. Aminoacid dehydrogenase-like, N-terminal domain [53222] (1)
       1. Aminoacid dehydrogenase-like, N-terminal domain [53223] (1)
          1. Aminoacid dehydrogenases [53224] (1)
             1. Glutamate dehydrogenase [53225]
                1. Clostridium symbiosum [53226] (2)
   14. Flavodoxin-like [52171] (6)
       1. CheY-like [52172] (1)
          1. CheY-related [52173] (6)
             1. CheY protein [52174]
                1. Escherichia coli [52175] (7)
                2. Salmonella typhimurium [52176] (4)
                3. Thermotoga maritima [52177] (2)
             2. Nitrate/nitrite response regulator (NarL), receiver domain [52178]
                1. Escherichia coli [52179] (1)
             3. NTRC receiver domain [52180]
                1. Salmonella typhimurium [52181] (1)
             4. Sporulation response regulator Spo0F [52188]
                1. Bacillus subtilis [52189] (3)
       2. Flavoproteins [52218] (1)
          1. Flavodoxin-related [52219] (6)
             1. Flavodoxin [52220]
                1. Chondrus crispus [52221] (1)
                2. Desulfovibrio vulgaris [52222] (12)
                3. Anabaena, pcc 7119 and 7120 [52223] (3)
                4. Escherichia coli [52224] (1)
                5. Anacystis nidulans and Synechococcus, pcc 7942 [52225] (1)
                6. Clostridium beijerinckii [52226] (16)
       3. Cobalamin (vitamin B12)-binding domain [52242] (1)
          1. Cobalamin (vitamin B12)-binding domain [52243] (2)
             1. Glutamate mutase, small subunit [52246]
                1. Clostridium tetanomorphum [52247] (1)
                2. Clostridium cochlearium [52248] (1)
       4. SGNH hydrolase [52266] (2)
          1. Esterase [52267] (1)
             1. Esterase [52268]
                1. Streptomyces scabies [52269] (3)
          2. Acetylhydrolase [52273] (1)
             1. Platelet-activating factor acetylhydrolase [52274]
                1. Cow (Bos taurus), alpha1 [52275] (4)
       5. Formate/glycerate dehydrogenase catalytic domain-like [52283] (1)
          1. Formate/glycerate dehydrogenases, substrate-binding domain [52284] (1)
             1. D-2-hydroxyisocaproate dehydrogenase [52289]
                1. Lactobacillus casei [52290] (1)
       6. Class I glutamine amidotransferase-like [52317] (1)
          1. Class I glutamine amidotransferases (GAT) [52318] (1)
             1. FGAM synthase PurL, amidotransferase domain [110484]
                1. Salmonella typhimurium [110485] (1)
   15. Ferredoxin reductase-like, C-terminal NADP-linked domain [52342] (1)
       1. Ferredoxin reductase-like, C-terminal NADP-linked domain [52343] (2)
          1. Reductases [52344] (6)
             1. Ferredoxin reductase (flavodoxin reductase) [52345]
                1. Spinach (Spinacia oleracea) [52346] (4)
                2. Cyanobacterium (Anabaena sp.), pcc 7119 [52350] (3)
                3. Escherichia coli [52351] (1)
                4. Azotobacter vinelandii [52352] (1)
             2. Nitrate reductase [52355]
                1. Corn (Zea mays) [52356] (3)
             3. cytochrome b5 reductase [52357]
                1. Pig (Sus scrofa), liver [52358] (1)
          2. Aromatic dioxygenase reductase-like [52359] (1)
             1. Phthalate dioxygenase reductase [52360]
                1. Pseudomonas cepacia, db01 [52361] (1)
   16. Adenine nucleotide alpha hydrolase-like [52373] (2)
       1. Nucleotidylyl transferase [52374] (1)
          1. Class I aminoacyl-tRNA synthetases (RS), catalytic domain [52375] (4)
             1. Tyrosyl-tRNA synthetase (TyrRS) [52376]
                1. Bacillus stearothermophilus, nca 1503 [52377] (3)
             2. Glutamyl-tRNA synthetase (GluRS) [52382]
                1. Thermus thermophilus [52383] (1)
             3. Methionyl-tRNA synthetase (MetRS) [52384]
                1. Thermus thermophilus [52385] (1)
             4. Isoleucyl-tRNA synthetase (IleRS) [52387]
                1. Thermus thermophilus [52388] (1)
       2. Adenine nucleotide alpha hydrolases-like [52402] (1)
          1. Phosphoadenylyl sulphate (PAPS) reductase [52410] (1)
             1. Phosphoadenylyl sulphate (PAPS) reductase [52411]
                1. Escherichia coli [52412] (1)
   17. Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain [52417] (1)
       1. Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain [52418] (1)
          1. Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain [52419] (1)
             1. Thymidine phosphorylase [52420]
                1. Escherichia coli [52421] (3)
   18. Cryptochrome/photolyase, N-terminal domain [52424] (1)
       1. Cryptochrome/photolyase, N-terminal domain [52425] (1)
          1. Cryptochrome/photolyase, N-terminal domain [52426] (1)
             1. DNA photolyase [52427]
                1. Anacystis nidulans [52429] (1)
   19. PIN domain-like [88722] (1)
       1. PIN domain-like [88723] (1)
          1. 5' to 3' exonuclease catalytic domain [53045] (3)
             1. T4 RNase H [53046]
                1. Bacteriophage T4 [53047] (1)
             2. 5' to 3' exonuclease domain of DNA polymerase Taq [53048]
                1. Thermus aquaticus [53049] (1)
             3. Flap endonuclease-1 (Fen-1 nuclease) [53052]
                1. Archaeon Methanococcus jannaschii [53053] (2)
   20. PreATP-grasp domain [52439] (1)
       1. PreATP-grasp domain [52440] (2)
          1. D-Alanine ligase N-terminal domain [52452] (1)
             1. D-Ala-D-Ala ligase, N-domain [52453]
                1. Escherichia coli, gene ddlB [52454] (3)
          2. Prokaryotic glutathione synthetase, N-terminal domain [52457] (1)
             1. Prokaryotic glutathione synthetase, N-terminal domain [52458]
                1. Escherichia coli [52459] (4)
   21. DHS-like NAD/FAD-binding domain [52466] (1)
       1. DHS-like NAD/FAD-binding domain [52467] (2)
          1. Deoxyhypusine synthase, DHS [52468] (1)
             1. Deoxyhypusine synthase, DHS [52469]
                1. Human (Homo sapiens) [52470] (1)
          2. Pyruvate oxidase and decarboxylase, middle domain [52475] (1)
             1. Benzoylformate decarboxylase [52482]
                1. Pseudomonas putida [52483] (1)
   22. Tubulin nucleotide-binding domain-like [52489] (1)
       1. Tubulin nucleotide-binding domain-like [52490] (1)
          1. Tubulin, GTPase domain [52491] (1)
             1. Cell-division protein FtsZ [52492]
                1. Archaeon Methanococcus jannaschii [52493] (1)
   23. HAD-like [56783] (1)
       1. HAD-like [56784] (1)
          1. L-2-Haloacid dehalogenase, HAD [56785] (1)
             1. L-2-Haloacid dehalogenase, HAD [56786]
                1. Pseudomonas sp., strain YL [56787] (3)
   24. Thiamin diphosphate-binding fold (THDP-binding) [52517] (1)
       1. Thiamin diphosphate-binding fold (THDP-binding) [52518] (2)
          1. Pyruvate oxidase and decarboxylase Pyr module [88724] (1)
             1. Benzoylformate decarboxylase [88731]
                1. Pseudomonas putida [88732] (1)
          2. Pyruvate oxidase and decarboxylase PP module [88749] (1)
             1. Benzoylformate decarboxylase [88756]
                1. Pseudomonas putida [88757] (1)
   25. P-loop containing nucleoside triphosphate hydrolases [52539] (1)
       1. P-loop containing nucleoside triphosphate hydrolases [52540] (10)
          1. Nucleotide and nucleoside kinases [52541] (8)
             1. Guanylate kinase [52542]
                1. Baker's yeast (Saccharomyces cerevisiae) [52543] (1)
             2. Uridylate kinase [52544]
                1. Baker's yeast (Saccharomyces cerevisiae) [52545] (2)
             3. UMP/CMP kinase [52550]
                1. Dictyostelium discoideum [52551] (4)
             4. Thymidine kinase [52552]
                1. Herpes simplex virus type 1, different strains [52553] (3)
             5. Adenylate kinase [52554]
                1. Pig (Sus scrofa) [52555] (1)
                2. Cow (Bos taurus), mitochondrial izozyme-2 [52558] (2)
                3. Baker's yeast (Saccharomyces cerevisiae) [52559] (3)
                4. Bacillus stearothermophilus [52562] (3)
          2. Phosphoribulokinase/pantothenate kinase [52584] (1)
             1. Phosphoribulokinase [52585]
                1. Rhodobacter sphaeroides [52586] (1)
          3. 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain [52589] (1)
             1. 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain [52590]
                1. Rat (Rattus norvegicus) [52591] (1)
          4. G proteins [52592] (11)
             1. cH-p21 Ras protein [52593]
                1. Human (Homo sapiens) [52594] (24)
             2. Rac [52595]
                1. Human (Homo sapiens) [52596] (1)
             3. Rap2a [52599]
                1. Human (Homo sapiens) [52600] (2)
             4. RhoA [52612]
                1. Human (Homo sapiens) [52613] (2)
             5. ADP-ribosylation factor [52614]
                1. Rat (Rattus norvegicus), ARF1 [52616] (1)
             6. CDC42 [52619]
                1. Human (Homo sapiens) [52620] (1)
             7. Transducin (alpha subunit) [52623]
                1. Cow (Bos taurus) [52624] (1)
                2. Rat (Rattus norvegicus) [52625] (10)
             8. Elongation factor Tu (EF-Tu), N-terminal (G) domain [52626]
                1. Escherichia coli [52627] (2)
                2. Thermus aquaticus [52628] (1)
             9. Elongation factor G (EF-G), N-terminal (G) domain [52633]
                1. Thermus thermophilus [52634] (2)
          5. Motor proteins [52641] (3)
             1. Myosin S1, motor domain [52642]
                1. Slime mold (Dictyostelium discoideum) [52645] (8)
             2. Kinesin [52646]
                1. Human (Homo sapiens) [52647] (1)
             3. Kinesin motor Ncd (non-claret disjunctional) [52649]
                1. Baker's yeast (Saccharomyces cerevisiae), Kar [52651] (1)
          6. Nitrogenase iron protein-like [52652] (4)
             1. Dethiobiotin synthetase [52653]
                1. Escherichia coli [52654] (10)
             2. Adenylosuccinate synthetase, PurA [52655]
                1. Escherichia coli [52656] (7)
             3. GTPase domain of the signal sequence recognition protein Ffh [52664]
                1. Thermus aquaticus [52665] (3)
             4. GTPase domain of the signal recognition particle receptor FtsY [52666]
                1. Escherichia coli [52667] (1)
          7. RecA protein-like (ATPase-domain) [52670] (1)
             1. RecA protein, ATPase-domain [52671]
                1. Escherichia coli [52672] (2)
          8. Tandem AAA-ATPase domain [81268] (1)
             1. DEXX box DNA helicase [52701]
                1. Bacillus stearothermophilus, PcrA [52702] (2)
          9. Extended AAA-ATPase domain [81269] (3)
             1. delta prime subunit of DNA polymerase III, N-domain [52711]
                1. Escherichia coli [52712] (1)
             2. Hexamerization domain of N-ethylmalemide-sensitive fusion (NSF) protein [52717]
                1. Chinese hamster (Cricetulus griseus) [52718] (1)
             3. Replication factor C1 [110566]
                1. Baker's yeast (Saccharomyces cerevisiae) [110567] (1)
          10. RNA helicase [52724] (1)
              1. HCV helicase domain [52725]
                 1. Human hepatitis C virus (HCV), different isolates [52726] (2)
   26. PTS IIb component [52727] (1)
       1. PTS IIb component [52728] (1)
          1. PTS IIb component [52729] (1)
             1. Fructose permease, subunit IIb [52730]
                1. Bacillus subtilis [52731] (1)
   27. Methylesterase CheB, C-terminal domain [52737] (1)
       1. Methylesterase CheB, C-terminal domain [52738] (1)
          1. Methylesterase CheB, C-terminal domain [52739] (1)
             1. Methylesterase CheB, C-terminal domain [52740]
                1. Salmonella typhimurium [52741] (1)
   28. Subtilisin-like [52742] (1)
       1. Subtilisin-like [52743] (1)
          1. Subtilases [52744] (9)
             1. Subtilisin [52745]
                1. Bacillus subtilis, carlsberg [52746] (1)
                2. Bacillus licheniformis [52748] (12)
                3. Bacillus lentus, savinase (TM) [52749] (1)
                4. Bacillus lentus [52750] (3)
                5. Bacillus amyloliquefaciens, Novo/BPN' [52751] (20)
             2. M-proteinase [52754]
                1. Bacillus sp., strain ksm-k16 [52755] (1)
             3. Serine protease PB92 (subtilisin PB92) [52756]
                1. Bacillus alcalophilus, Bacillus lentus [52757] (1)
             4. Thermitase [52760]
                1. Thermoactinomyces vulgaris [52761] (1)
             5. Proteinase K [52762]
                1. Fungus (Tritirachium album), strain limber [52763] (3)
   29. CoA-dependent acyltransferases [52776] (1)
       1. CoA-dependent acyltransferases [52777] (1)
          1. CAT-like [52778] (4)
             1. Chloramphenicol acetyltransferase, CAT [52779]
                1. Escherichia coli [52780] (5)
                2. Shigella flexneri [52781] (1)
             2. Dihydrolipoamide acetyltransferase [52782]
                1. Azotobacter vinelandii [52783] (9)
             3. Dihydrolipoamide succinyltransferase [52785]
                1. Escherichia coli [52786] (1)
   30. Phosphotyrosine protein phosphatases I-like [52787] (2)
       1. Phosphotyrosine protein phosphatases I [52788] (1)
          1. Low-molecular-weight phosphotyrosine protein phosphatases [52789] (2)
             1. Tyrosine phosphatase [52790]
                1. Cow (Bos taurus) [52791] (3)
                2. Human (Homo sapiens) [52792] (1)
       2. PTS system, Lactose/Cellobiose specific IIB subunit [52794] (1)
          1. PTS system, Lactose/Cellobiose specific IIB subunit [52795] (1)
             1. Enzyme IIB-cellobiose [52796]
                1. Escherichia coli [52797] (1)
   31. (Phosphotyrosine protein) phosphatases II [52798] (1)
       1. (Phosphotyrosine protein) phosphatases II [52799] (2)
          1. Dual specificity phosphatase-like [52800] (1)
             1. Mapk phosphatase [52803]
                1. Human (Homo sapiens), pyst1 (mkp3) [52804] (1)
          2. Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (3)
             1. Tyrosine phosphatase [52806]
                1. Human (Homo sapiens), 1B [52807] (5)
                2. Human (Homo sapiens), shp-1 [52811] (1)
             2. Protein-tyrosine phosphatase YopH, catalytic domain [100952]
                1. Yersinia enterocolitica [52812] (3)
   32. Rhodanese/Cell cycle control phosphatase [52820] (1)
       1. Rhodanese/Cell cycle control phosphatase [52821] (2)
          1. Cell cycle control phosphatase, catalytic domain [52822] (1)
             1. CDC25a [52823]
                1. Human (Homo sapiens) [52824] (1)
          2. Sulfurtransferase (rhodanese) [52827] (2)
             1. Rhodanese [52828]
                1. Cow (Bos taurus) [52829] (12)
             2. Sulfurtransferase [52830]
                1. Thermus thermophilus [110602] (1)
   33. Thioredoxin fold [52832] (1)
       1. Thioredoxin-like [52833] (5)
          1. Thioltransferase [52834] (9)
             1. Thioredoxin [52835]
                1. Escherichia coli [52836] (4)
                2. Anabaena sp., pcc 7120 [52837] (1)
                3. Chlamydomonas reinhardtii [52838] (1)
                4. Human (Homo sapiens) [52842] (12)
             2. Glutaredoxin (Grx, thioltransferase) [52843]
                1. Bacteriophage T4 [52844] (1)
                2. Escherichia coli [52845] (3)
                3. Escherichia coli, Grx3 [52846] (1)
                4. Pig (Sus scrofa) [52847] (1)
                5. Human (Homo sapiens) [52848] (1)
          2. PDI-like [52849] (2)
             1. Protein disulfide isomerase, PDI [52850]
                1. Human (Homo sapiens) [52851] (2)
                2. Archaeon Pyrococcus furiosus [52852] (2)
          3. Calsequestrin [52855] (1)
             1. Calsequestrin [52856]
                1. Rabbit (Oryctolagus cuniculus) [52857] (3)
          4. DsbA-like [100953] (2)
             1. Disulfide-bond formation facilitator (DsbA) [100954]
                1. Escherichia coli [100955] (3)
                2. Vibrio cholerae [100956] (1)
          5. Glutathione S-transferase (GST), N-terminal domain [52862] (6)
             1. Class mu GST [81359]
                1. Human (Homo sapiens) [52867] (1)
             2. Class alpha GST [81360]
                1. Schistosoma japonicum [52878] (4)
                2. Fasciola hepatica [52879] (1)
             3. Class sigma GST [81362]
                1. Squid (Ommastrephes sloani pacificus) [52876] (2)
             4. Class phi GST [81367]
                1. Maize (Zea mays), type III [52882] (1)
             5. Class beta GST [81368]
                1. Proteus mirabilis [52884] (1)
   34. Pyruvate kinase C-terminal domain-like [52934] (1)
       1. PK C-terminal domain-like [52935] (1)
          1. Pyruvate kinase, C-terminal domain [52936] (2)
             1. Pyruvate kinase, C-terminal domain [52937]
                1. Cat (Felis catus) [52938] (1)
                2. Rabbit (Oryctolagus cuniculus) [52939] (1)
   35. Restriction endonuclease-like [52979] (1)
       1. Restriction endonuclease-like [52980] (3)
          1. Restriction endonuclease BamHI [52987] (1)
             1. Restriction endonuclease BamHI [52988]
                1. Bacillus amyloliquefaciens [52989] (1)
          2. Cfr10I/Bse634I [52999] (1)
             1. Restriction endonuclease Cfr10I [53000]
                1. Citrobacter freundii [53001] (1)
          3. DNA mismatch repair protein MutH from [53020] (1)
             1. DNA mismatch repair protein MutH from [53021]
                1. Escherichia coli [53022] (1)
   36. Resolvase-like [53040] (1)
       1. Resolvase-like [53041] (1)
          1. gamma,delta resolvase, catalytic domain [53042] (1)
             1. gamma,delta resolvase, catalytic domain [53043]
                1. Escherichia coli [53044] (1)
   37. IIA domain of mannose transporter, IIA-Man [53061] (1)
       1. IIA domain of mannose transporter, IIA-Man [53062] (1)
          1. IIA domain of mannose transporter, IIA-Man [53063] (1)
             1. IIA domain of mannose transporter, IIA-Man [53064]
                1. Escherichia coli [53065] (1)
   38. Ribonuclease H-like motif [53066] (4)
       1. Actin-like ATPase domain [53067] (2)
          1. Actin/HSP70 [53068] (1)
             1. Heat shock protein 70kDa, ATPase fragment [53069]
                1. Cow (Bos taurus) [53070] (38)
          2. Hexokinase [53083] (1)
             1. Hexokinase [53084]
                1. Blood fluke (Schistosoma mansoni) [53085] (2)
       2. Creatinase/prolidase N-terminal domain [53092] (1)
          1. Creatinase/prolidase N-terminal domain [53093] (1)
             1. Aminopeptidase P [53096]
                1. Escherichia coli [53097] (2)
       3. Ribonuclease H-like [53098] (4)
          1. Ribonuclease H [53099] (2)
             1. RNase H (RNase HI) [53100]
                1. Escherichia coli [53101] (20)
                2. Thermus thermophilus [53102] (1)
          2. Retroviral integrase, catalytic domain [53107] (2)
             1. Retroviral integrase, catalytic domain [53108]
                1. Rous sarcoma virus (RSV, avian sarcoma virus) [53109] (13)
                2. Human immunodeficiency virus type 1 [53110] (3)
          3. mu transposase, core domain [53112] (1)
             1. mu transposase, core domain [53113]
                1. Bacteriophage mu [53114] (1)
          4. DnaQ-like 3'-5' exonuclease [53118] (4)
             1. Exonuclease domain of prokaryotic DNA polymerase [53119]
                1. Escherichia coli [53120] (2)
                2. Thermus aquaticus [53121] (3)
                3. Bacillus stearothermophilus, newly identified strain as yet unnamed [53122] (1)
             2. Exonuclease domain of family B DNA polymerases [53125]
                1. Bacteriophage RB69 [53127] (1)
       4. Methylated DNA-protein cysteine methyltransferase domain [53155] (1)
          1. Methylated DNA-protein cysteine methyltransferase domain [53156] (1)
             1. Ada DNA repair protein [53157]
                1. Escherichia coli [53158] (1)
   39. Phosphorylase/hydrolase-like [53162] (3)
       1. Purine and uridine phosphorylases [53167] (1)
          1. Purine and uridine phosphorylases [53168] (2)
             1. Purine nucleoside phosphorylase, PNP [53169]
                1. Human (Homo sapiens) [53170] (2)
                2. Cow (Bos taurus) [53171] (10)
       2. Peptidyl-tRNA hydrolase-like [53178] (1)
          1. Peptidyl-tRNA hydrolase-like [53179] (1)
             1. Peptidyl-tRNA hydrolase [53180]
                1. Escherichia coli [53181] (1)
       3. Zn-dependent exopeptidases [53187] (4)
          1. Pancreatic carboxypeptidases [53188] (5)
             1. Carboxypeptidase A [53189]
                1. Cow (Bos taurus) [53190] (13)
                2. Pig (Sus scrofa) [53191] (1)
                3. Human (Homo sapiens) [53192] (1)
             2. Carboxypeptidase B [53193]
                1. Pig (Sus scrofa) [53194] (1)
                2. Cow (Bos taurus) [53195] (1)
          2. Carboxypeptidase T [53198] (1)
             1. Carboxypeptidase T [53199]
                1. Thermoactinomyces vulgaris [53200] (1)
          3. Leucine aminopeptidase, C-terminal domain [53201] (1)
             1. Leucine aminopeptidase, C-terminal domain [53202]
                1. Cow (Bos taurus) [53203] (4)
          4. Bacterial dinuclear zinc exopeptidases [53204] (2)
             1. Aminopeptidase [53205]
                1. Aeromonas proteolytica [53206] (2)
                2. Streptomyces griseus [53207] (1)
   40. Macro domain-like [52948] (1)
       1. Macro domain-like [52949] (1)
          1. Leucine aminopeptidase (Aminopeptidase A), N-terminal domain [52950] (1)
             1. Leucine aminopeptidase (Aminopeptidase A), N-terminal domain [52951]
                1. Cow (Bos taurus) [52952] (4)
   41. MurD-like peptide ligases, peptide-binding domain [53243] (1)
       1. MurD-like peptide ligases, peptide-binding domain [53244] (2)
          1. MurCDEF C-terminal domain [53245] (1)
             1. UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase MurD [53246]
                1. Escherichia coli [53247] (1)
          2. Folylpolyglutamate synthetase, C-terminal domain [53250] (1)
             1. Folylpolyglutamate synthetase, C-terminal domain [53251]
                1. Lactobacillus casei [53252] (1)
   42. Phosphoglycerate mutase-like [53253] (1)
       1. Phosphoglycerate mutase-like [53254] (3)
          1. Cofactor-dependent phosphoglycerate mutase [53255] (1)
             1. Phosphoglycerate mutase [53256]
                1. Baker's yeast (Saccharomyces cerevisiae) [53257] (1)
          2. Histidine acid phosphatase [53258] (2)
             1. Prostatic acid phosphatase [53259]
                1. Rat (Rattus norvegicus) [53260] (2)
             2. Phytase (myo-inositol-hexakisphosphate-3-phosphohydrolase) [53263]
                1. Aspergillus ficuum [53264] (1)
          3. 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain [53267] (1)
             1. 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain [53268]
                1. Rat (Rattus norvegicus) [53269] (1)
   43. PRTase-like [53270] (1)
       1. PRTase-like [53271] (1)
          1. Phosphoribosyltransferases (PRTases) [53272] (2)
             1. Orotate PRTase [53290]
                1. Salmonella typhimurium [53291] (2)
             2. Pyrimidine operon regulator PyrR [109612]
                1. Bacillus subtilis [53294] (1)
   44. vWA-like [53299] (1)
       1. vWA-like [53300] (1)
          1. Integrin A (or I) domain [53301] (3)
             1. Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1) [53302]
                1. Human (Homo sapiens) [53303] (1)
             2. von Willebrand factor A1 domain, vWA1 [53306]
                1. Human (Homo sapiens) [53307] (1)
             3. Integrin alpha M (CR3, CD11b/CD18, Mac-1 alpha subunit) [53308]
                1. Human (Homo sapiens) [53309] (2)
   45. FabD/lysophospholipase-like [52150] (1)
       1. FabD/lysophospholipase-like [52151] (1)
          1. FabD-like [52152] (1)
             1. Catalytic domain of malonyl-CoA ACP transacylase FabD [52153]
                1. Escherichia coli [52154] (1)
   46. Formyltransferase [53327] (1)
       1. Formyltransferase [53328] (1)
          1. Formyltransferase [53329] (1)
             1. Glycinamide ribonucleotide transformylase, GART [53330]
                1. Escherichia coli [53331] (3)
   47. S-adenosyl-L-methionine-dependent methyltransferases [53334] (1)
       1. S-adenosyl-L-methionine-dependent methyltransferases [53335] (5)
          1. Catechol O-methyltransferase, COMT [53336] (1)
             1. Catechol O-methyltransferase, COMT [53337]
                1. Rat (Rattus norvegicus) [53338] (1)
          2. rRNA adenine dimethylase-like [88784] (1)
             1. rRNA adenine dimethylase [53363]
                1. Streptococcus pneumoniae, Ermam [53364] (1)
          3. mRNA cap methylase [88785] (1)
             1. Polymerase regulatory subunit VP39 [53361]
                1. Vaccinia virus [53362] (12)
          4. Chemotaxis receptor methyltransferase CheR, C-terminal domain [53357] (1)
             1. Chemotaxis receptor methyltransferase CheR, C-terminal domain [53358]
                1. Salmonella typhimurium [53359] (1)
          5. C5 cytosine-specific DNA methylase, DCM [88786] (1)
             1. DNA methylase HhaI [53367]
                1. Haemophilus haemolyticus [53368] (1)
   48. PLP-dependent transferases [53382] (1)
       1. PLP-dependent transferases [53383] (2)
          1. AAT-like [53384] (3)
             1. Aspartate aminotransferase, AAT [53385]
                1. Chicken (Gallus gallus), mitochondria [53386] (4)
                2. Chicken (Gallus gallus), cytosolic form [53387] (1)
                3. Escherichia coli [53390] (18)
          2. GABA-aminotransferase-like [53417] (1)
             1. Dialkylglycine decarboxylase [53418]
                1. Pseudomonas cepacia [53419] (4)
   49. alpha/beta-Hydrolases [53473] (1)
       1. alpha/beta-Hydrolases [53474] (9)
          1. Acetylcholinesterase-like [53475] (2)
             1. Acetylcholinesterase [53476]
                1. Electric ray (Torpedo californica) [53477] (9)
             2. Bile-salt activated lipase (cholesterol esterase) [53482]
                1. Cow (Bos taurus) [53483] (2)
          2. Serine carboxypeptidase-like [53499] (2)
             1. Serine carboxypeptidase II [53500]
                1. Baker's yeast (Saccharomyces cerevisiae) [53502] (2)
                2. Baker's yeast (Saccharomyces cerevisiae), kex1(delta)p [53503] (1)
          3. Haloalkane dehalogenase [53513] (1)
             1. Haloalkane dehalogenase [53514]
                1. Xanthobacter autotrophicus [53515] (13)
          4. Dienelactone hydrolase [53518] (1)
             1. Dienelactone hydrolase [53519]
                1. Pseudomonas sp., B13 [53520] (1)
          5. Haloperoxidase [53531] (3)
             1. Bromoperoxidase A2 [53532]
                1. Streptomyces aureofaciens [53533] (1)
             2. Bromoperoxidase A1 [53534]
                1. Streptomyces aureofaciens [53535] (1)
             3. Chloroperoxidase F [53540]
                1. Pseudomonas fluorescens [53541] (1)
          6. Fungal lipases [53558] (6)
             1. Triacylglycerol lipase [53559]
                1. Yeast (Candida antarctica), form b [53560] (3)
                2. Rhizomucor miehei [53561] (4)
                3. Penicillium camembertii [53562] (1)
                4. Thermomyces (Humicola) lanuginosa [53563] (1)
             2. Type-B carboxylesterase/lipase [53566]
                1. Fungus (Geotrichum candidum), ATCC 34614 [53567] (1)
                2. Fungus (Candida rugosa), formerly Cylindracea [53568] (7)
          7. Bacterial lipase [53570] (2)
             1. Lipase [53571]
                1. Burkholderia cepacia (formerly Pseudomonas cepacia) [63399] (3)
                2. Chromobacterium viscosum [53576] (1)
          8. Pancreatic lipase, N-terminal domain [53577] (2)
             1. Pancreatic lipase, N-terminal domain [53578]
                1. Guinea pig (Cavia porcellus) [53582] (1)
                2. Dog (Canis familiaris) [53583] (1)
          9. Cutinase-like [52260] (2)
             1. Cutinase [52261]
                1. Fungus (Fusarium solani), subsp. pisi [52262] (35)
             2. Acetylxylan esterase [52263]
                1. Penicillium purpurogenum [52264] (2)
   50. Dihydrofolate reductases [53596] (1)
       1. Dihydrofolate reductases [53597] (1)
          1. Dihydrofolate reductases [53598] (5)
             1. Dihydrofolate reductase, prokaryotic type [53599]
                1. Escherichia coli [53600] (24)
                2. Lactobacillus casei [53601] (5)
             2. Dihydrofolate reductases, eukaryotic type [53605]
                1. Chicken (Gallus gallus) [53606] (8)
                2. Human (Homo sapiens) [53607] (8)
                3. Fungus (Pneumocystis carinii) [53608] (2)
   51. Ribokinase-like [53612] (2)
       1. Ribokinase-like [53613] (2)
          1. Thiamin biosynthesis kinases [53620] (1)
             1. Hydroxyethylthiazole kinase (THZ kinase, ThiK) [53621]
                1. Bacillus subtilis [53622] (3)
          2. Ribokinase-like [53614] (1)
             1. Ribokinase [53615]
                1. Escherichia coli [53616] (1)
       2. MurD-like peptide ligases, catalytic domain [53623] (2)
          1. MurCDEF [53624] (1)
             1. UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase MurD [53625]
                1. Escherichia coli [53626] (1)
          2. Folylpolyglutamate synthetase [53629] (1)
             1. Folylpolyglutamate synthetase [53630]
                1. Lactobacillus casei [53631] (1)
   52. Alkaline phosphatase-like [53648] (1)
       1. Alkaline phosphatase-like [53649] (1)
          1. Arylsulfatase [53653] (2)
             1. Arylsulfatase A [53654]
                1. Human (Homo sapiens) [53655] (1)
             2. Arylsulfatase B (4-sulfatase) [53656]
                1. Human (Homo sapiens) [53657] (1)
   53. AraD-like aldolase/epimerase [53638] (1)
       1. AraD-like aldolase/epimerase [53639] (1)
          1. AraD-like aldolase/epimerase [53640] (1)
             1. L-fuculose-1-phosphate aldolase [53641]
                1. Escherichia coli [53642] (4)
   54. Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1)
       1. Isocitrate/Isopropylmalate dehydrogenase-like [53659] (1)
          1. Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (3)
             1. 3-isopropylmalate dehydrogenase, IPMDH [53661]
                1. Thermus thermophilus [53662] (5)
                2. Chimera (Thermus thermophilus) and (Bacillus subtilis) [53663] (2)
             2. Isocitrate dehydrogenase, ICDH [53668]
                1. Escherichia coli [53669] (19)
   55. ATC-like [53670] (1)
       1. Aspartate/ornithine carbamoyltransferase [53671] (1)
          1. Aspartate/ornithine carbamoyltransferase [53672] (1)
             1. Ornithine transcarbamoylase [53676]
                1. Archaeon Pyrococcus furiosus [53679] (2)
   56. Tryptophan synthase beta subunit-like PLP-dependent enzymes [53685] (1)
       1. Tryptophan synthase beta subunit-like PLP-dependent enzymes [53686] (1)
          1. Tryptophan synthase beta subunit-like PLP-dependent enzymes [53687] (1)
             1. Allosteric threonine deaminase N-terminal domain [53692]
                1. Escherichia coli [53693] (1)
   57. SIS domain [53696] (1)
       1. SIS domain [53697] (2)
          1. double-SIS domain [53698] (1)
             1. "Isomerase domain" of glucosamine 6-phosphate synthase (GLMS) [53699]
                1. Escherichia coli [53700] (2)
          2. Phosphoglucose isomerase, PGI [53701] (1)
             1. Phosphoglucose isomerase, PGI [53702]
                1. Bacillus stearothermophilus [53704] (1)
   58. Formate dehydrogenase/DMSO reductase, domains 1-3 [53705] (1)
       1. Formate dehydrogenase/DMSO reductase, domains 1-3 [53706] (1)
          1. Formate dehydrogenase/DMSO reductase, domains 1-3 [53707] (3)
             1. Dimethylsulfoxide reductase (DMSO reductase) [53708]
                1. Rhodobacter capsulatus [53710] (5)
             2. Formate dehydrogenase H [53711]
                1. Escherichia coli [53712] (3)
             3. Trimethylamine N-oxide reductase [53713]
                1. Shewanella massilia [53714] (1)
   59. Aconitase iron-sulfur domain [53731] (1)
       1. Aconitase iron-sulfur domain [53732] (1)
          1. Aconitase iron-sulfur domain [53733] (2)
             1. Aconitase A, N-terminal domain [53734]
                1. Pig (Sus scrofa) [53735] (3)
                2. Cow (Bos taurus) [53736] (7)
   60. Phosphoglycerate kinase [53747] (1)
       1. Phosphoglycerate kinase [53748] (1)
          1. Phosphoglycerate kinase [53749] (4)
             1. Phosphoglycerate kinase [53750]
                1. Baker's yeast (Saccharomyces cerevisiae) [53751] (2)
                2. Bacillus stearothermophilus [53752] (1)
                3. Thermotoga maritima [53753] (1)
                4. Trypanosoma brucei [53754] (1)
   61. UDP-Glycosyltransferase/glycogen phosphorylase [53755] (1)
       1. UDP-Glycosyltransferase/glycogen phosphorylase [53756] (2)
          1. beta-Glucosyltransferase (DNA-modifying) [53757] (1)
             1. beta-Glucosyltransferase (DNA-modifying) [53758]
                1. Bacteriophage T4 [53759] (4)
          2. Oligosaccharide phosphorylase [53766] (1)
             1. Glycogen phosphorylase [53767]
                1. Rabbit (Oryctolagus cuniculus) [53769] (13)
   62. Glutaminase/Asparaginase [53773] (1)
       1. Glutaminase/Asparaginase [53774] (1)
          1. Glutaminase/Asparaginase [53775] (1)
             1. Glutaminase-asparaginase [53780]
                1. Acinetobacter glutaminasificans [53781] (1)
   63. Phosphofructokinase [53783] (1)
       1. Phosphofructokinase [53784] (1)
          1. Phosphofructokinase [53785] (1)
             1. ATP-dependent phosphofructokinase [53786]
                1. Bacillus stearothermophilus [53788] (2)
   64. Tetrapyrrole methylase [53789] (1)
       1. Tetrapyrrole methylase [53790] (1)
          1. Tetrapyrrole methylase [53791] (1)
             1. Cobalt precorrin-4 methyltransferase CbiF [53792]
                1. Bacillus megaterium [53793] (2)
   65. PEP carboxykinase-like [53794] (1)
       1. PEP carboxykinase-like [53795] (1)
          1. PEP carboxykinase C-terminal domain [53796] (1)
             1. Phosphoenolpyruvate (PEP) carboxykinase (ATP-oxaloacetate carboxy-lyase) [68921]
                1. Escherichia coli [53798] (3)
   66. PEP carboxykinase N-terminal domain [68922] (1)
       1. PEP carboxykinase N-terminal domain [68923] (1)
          1. PEP carboxykinase N-terminal domain [68924] (1)
             1. Phosphoenolpyruvate (PEP) carboxykinase (ATP-oxaloacetate carboxy-lyase) [68925]
                1. Escherichia coli [68926] (3)
   67. Chelatase-like [53799] (1)
       1. Chelatase [53800] (1)
          1. Ferrochelatase [53801] (1)
             1. Ferrochelatase [53802]
                1. Bacillus subtilis [53803] (1)
   68. Periplasmic binding protein-like I [53821] (1)
       1. Periplasmic binding protein-like I [53822] (1)
          1. L-arabinose binding protein-like [53823] (7)
             1. D-ribose-binding protein [53824]
                1. Escherichia coli, strain k-12 [53825] (4)
             2. L-arabinose-binding protein [53826]
                1. Escherichia coli [53827] (9)
             3. Galactose/glucose-binding protein [53830]
                1. Escherichia coli [53831] (2)
                2. Salmonella typhimurium, strain lt2 [53832] (3)
             4. Amide receptor/negative regulator of the amidase operon (AmiC) [53833]
                1. Pseudomonas aeruginosa [53834] (1)
             5. Leucine-,isoleucine-,valine-binding (LIV) protein [53841]
                1. Escherichia coli [53842] (1)
             6. Leucine-binding protein [53843]
                1. Escherichia coli [53844] (1)
   69. Periplasmic binding protein-like II [53849] (1)
       1. Periplasmic binding protein-like II [53850] (2)
          1. Phosphate binding protein-like [53851] (12)
             1. Oligo-peptide binding protein (OPPA) [53852]
                1. Salmonella typhimurium [53853] (1)
             2. Porphobilinogen deaminase (hydroxymethylbilane synthase), N-terminal domain [53854]
                1. Escherichia coli [53855] (3)
             3. Lysine-,arginine-,ornithine-binding (LAO) protein [53856]
                1. Salmonella typhimurium [53857] (2)
             4. Sulphate-binding protein [53858]
                1. Salmonella typhimurium [53859] (1)
             5. Phosphate-binding protein [53860]
                1. Escherichia coli [53861] (10)
             6. D-maltodextrin-binding protein, MBP [53862]
                1. Escherichia coli [53863] (10)
             7. Ferric-binding protein FbpA [53867]
                1. Haemophilus influenzae [53868] (1)
             8. Dipeptide-binding protein [53870]
                1. Escherichia coli [53871] (1)
             9. Spermidine/putrescine-binding protein PotD [53875]
                1. Escherichia coli [53876] (1)
             10. Molybdate-binding protein, ModA [53883]
                 1. Escherichia coli [53884] (2)
                 2. Azotobacter vinelandii [53885] (1)
             11. Cofactor-binding fragment of LysR-type protein CysB [53886]
                 1. Klebsiella aerogenes [53887] (1)
          2. Transferrin [53888] (7)
             1. Lactoferrin [53889]
                1. Human (Homo sapiens) [53890] (15)
                2. Cow (Bos taurus) [53891] (2)
                3. Domestic water buffalo (Bubalus arnee bubalis) [53892] (2)
             2. Ovotransferrin [53894]
                1. Duck (Anas platyrhynchos) [53895] (5)
                2. Chicken (Gallus gallus) [53896] (5)
             3. Transferrin [53897]
                1. Rabbit (Oryctolagus cuniculus) [53898] (1)
                2. Human (Homo sapiens) [53899] (2)
   70. Thiolase-like [53900] (1)
       1. Thiolase-like [53901] (1)
          1. Thiolase-related [53902] (1)
             1. Beta-ketoacyl-ACP synthase II [53909]
                1. Escherichia coli [53910] (2)
   71. Cytidine deaminase-like [53926] (1)
       1. Cytidine deaminase-like [53927] (1)
          1. Cytidine deaminase [53928] (1)
             1. Two-domain cytidine deaminase [53929]
                1. Escherichia coli [53930] (6)
4. Alpha and beta proteins (a+b) [53931] (97)
   Mainly antiparallel beta sheets (segregated alpha and beta regions)
   1. Microbial ribonucleases [53932] (1)
      1. Microbial ribonucleases [53933] (2)
         1. Bacterial ribonucleases [81307] (1)
            1. Barnase [81305]
               1. Bacillus amyloliquefaciens [53945] (2)
         2. Fungal ribonucleases [81311] (4)
            1. RNase F1 [53937]
               1. Fusarium moniliforme [53938] (4)
            2. RNase T1 [53939]
               1. Aspergillus oryzae [53940] (27)
            3. RNase U2 [53942]
               1. Ustilago sphaerogena [53943] (1)
            4. RNase Ms [53947]
               1. Molsin (Aspergillus saitoi) [53948] (2)
   2. Lysozyme-like [53954] (1)
      1. Lysozyme-like [53955] (5)
         1. Family 19 glycosidase [53956] (1)
            1. Plant class II chitinase [53957]
               1. Barley (Hordeum vulgare) [53958] (1)
         2. C-type lysozyme [53960] (12)
            1. Lysozyme [53961]
               1. Chicken (Gallus gallus) [53962] (77)
               2. Turkey (Meleagris gallopavo) [53963] (8)
               3. Guinea fowl (Numida meleagris) [53964] (1)
               4. Bobwhite quail (Colinus virginianus) [53966] (1)
               5. Japanese quail (Coturnix coturnix japonica) [53967] (1)
               6. Human (Homo sapiens) [53969] (83)
               7. Horse (Equus caballus), milk [53970] (1)
               8. Australian echidna (Tachyglossus aculeatus) [53972] (1)
               9. Rainbow trout (Oncorhynchus mykiss) [53973] (7)
            2. alpha-Lactalbumin [53975]
               1. Baboon (Papio cynocephalus) [53976] (1)
               2. Human (Homo sapiens) [53977] (2)
               3. Guinea pig (Cavia porcellus) [53978] (1)
         3. Phage lysozyme [53981] (1)
            1. Phage T4 lysozyme [53982]
               1. Bacteriophage T4 [53983] (243)
         4. G-type lysozyme [53987] (2)
            1. Lysozyme [53988]
               1. Goose (Anser anser anser) [53989] (2)
               2. Australian black swan (Cygnus atratus) [53990] (2)
         5. Bacterial muramidase, catalytic domain [53991] (2)
            1. 70 kDa soluble lytic transglycosylase, SLT70 [53992]
               1. Escherichia coli [53993] (1)
            2. 36 kDa soluble lytic transglycosylase, SLT35 [53994]
               1. Escherichia coli [53995] (1)
   3. Cysteine proteinases [54000] (1)
      1. Cysteine proteinases [54001] (2)
         1. Papain-like [54002] (10)
            1. Actinidin [54003]
               1. Chinese gooseberry or kiwifruit (Actinidia chinensis) [54004] (2)
            2. Papain [54005]
               1. Papaya (Carica papaya) [54006] (12)
            3. Caricain (protease omega) [54007]
               1. Papaya (Carica papaya) [54008] (2)
            4. Chymopapain [54009]
               1. Papaya (Carica papaya) [54010] (1)
            5. Bleomycin hydrolase [54017]
               1. Baker's yeast (Saccharomyces cerevisiae), Gal6 [54018] (3)
            6. Cruzain [54020]
               1. Trypanosoma cruzi [54021] (2)
            7. (Pro)cathepsin B [54022]
               1. Human (Homo sapiens) [54023] (3)
            8. (Pro)cathepsin K [54028]
               1. Human (Homo sapiens) [54029] (9)
            9. (Pro)cathepsin L [54026]
               1. Human (Homo sapiens) [54027] (1)
            10. Staphopain StpA [54033]
                1. Staphylococcus aureus [54034] (1)
         2. Ubiquitin carboxyl-terminal hydrolase UCH-l3 [54050] (1)
            1. Ubiquitin carboxyl-terminal hydrolase UCH-l3 [54051]
               1. Human (Homo sapiens) [54052] (1)
   4. RNase A-like [54075] (1)
      1. RNase A-like [54076] (1)
         1. Ribonuclease A-like [54077] (5)
            1. Ribonuclease A (also ribonuclease B, S) [54078]
               1. Cow (Bos taurus) [54079] (55)
            2. Amphibian cytotoxic ribonuclease [54084]
               1. Frog (Rana pipiens), P-30 [54083] (1)
               2. Bullfrog (Rana catesbeiana) [54085] (1)
            3. Angiogenin [54094]
               1. Human (Homo sapiens) [54095] (2)
               2. Cow (Bos taurus) [54096] (2)
   5. Prion-like [54097] (1)
      1. Prion-like [54098] (1)
         1. Prion-like [54099] (1)
            1. Prion protein domain [54100]
               1. Mouse (Mus musculus) [54101] (1)
   6. IL8-like [54116] (1)
      1. Interleukin 8-like chemokines [54117] (1)
         1. Interleukin 8-like chemokines [54118] (6)
            1. Interleukin-8, IL-8 [54119]
               1. Human (Homo sapiens) [54120] (3)
            2. Monocyte chemoattractant protein-1 (MCP-1, MCAF) [54134]
               1. Human (Homo sapiens) [54135] (1)
            3. Eotaxin [54140]
               1. Human (Homo sapiens) [54141] (2)
            4. Monocyte chemoattractant protein-3 (MCP-3) [54144]
               1. Human (Homo sapiens) [54145] (1)
            5. Stromal cell-derived factor-1 (SDF-1) [54150]
               1. Human (Homo sapiens) [54151] (2)
            6. Chemokine hcc-2 (macrophage inflammatory protein-5) [54154]
               1. Human (Homo sapiens) [54155] (1)
   7. DNA-binding domain [54170] (1)
      1. DNA-binding domain [54171] (2)
         1. DNA-binding domain from tn916 integrase [54172] (1)
            1. DNA-binding domain from tn916 integrase [54173]
               1. Enterococcus faecalis [54174] (2)
         2. GCC-box binding domain [54175] (1)
            1. GCC-box binding domain [54176]
               1. Mouse-ear cress (Arabidopsis thaliana) [54177] (2)
   8. Penicillin-binding protein 2x (pbp-2x), c-terminal domain [54183] (1)
      1. Penicillin-binding protein 2x (pbp-2x), c-terminal domain [54184] (1)
         1. Penicillin-binding protein 2x (pbp-2x), c-terminal domain [54185] (1)
            1. Penicillin-binding protein 2x (pbp-2x), c-terminal domain [54186]
               1. Streptococcus pneumoniae [54187] (2)
   9. HIT-like [54196] (1)
      1. HIT-like [54197] (1)
         1. HIT (HINT, histidine triad) family of protein kinase-interacting proteins [54198] (3)
            1. Histidine triad nucleotide-binding protein (HINT) [54199]
               1. Rabbit (Oryctolagus cuniculus) [54200] (4)
            2. FHIT (fragile histidine triad protein) [54201]
               1. Human (Homo sapiens) [54202] (7)
            3. Protein kinase C inhibitor-1, PKCI-1 [54203]
               1. Human (Homo sapiens) [54204] (1)
   10. Ribosomal protein S5 domain 2-like [54210] (1)
       1. Ribosomal protein S5 domain 2-like [54211] (2)
          1. Translational machinery components [54212] (2)
             1. Elongation factor G (EF-G), domain IV [54213]
                1. Thermus thermophilus [54214] (2)
             2. Ribosomal protein S5, C-terminal domain [54215]
                1. Bacillus stearothermophilus [54216] (1)
          2. RNase P protein [54220] (1)
             1. RNase P protein [54221]
                1. Bacillus subtilis [54222] (1)
   11. beta-Grasp (ubiquitin-like) [54235] (7)
       1. Ubiquitin-like [54236] (2)
          1. Ubiquitin-related [54237] (2)
             1. Ubiquitin [54238]
                1. Human (Homo sapiens) [54239] (2)
             2. SUMO-1 (smt3 homologue) [54241]
                1. Human (Homo sapiens) [54242] (1)
          2. Ras-binding domain, RBD [54263] (4)
             1. c-Raf1 RBD [54264]
                1. Human (Homo sapiens) [54265] (1)
                2. Rat (Rattus norvegicus) [54266] (1)
             2. Ral guanosine-nucleotide exchange factor, RalGDS [54267]
                1. Human (Homo sapiens) [54269] (1)
             3. RalGDS-like factor, Rlf [54270]
                1. Mouse (Mus musculus) [54271] (1)
       2. 2Fe-2S ferredoxin-like [54292] (2)
          1. 2Fe-2S ferredoxin-related [54293] (9)
             1. 2Fe-2S ferredoxin [54294]
                1. Cyanobacterium (Anabaena sp.), pcc 7119 and 7120 [54295] (1)
                2. Spirulina platensis [54296] (1)
                3. Synechocystis sp., pcc 6803 [54298] (2)
                4. Synechococcus elongatus [54299] (3)
                5. Chlorella fusca [54300] (1)
                6. Archaeon Haloarcula marismortui [54302] (1)
                7. Parsley (Petroselinum crispum) [54303] (1)
                8. Spinach (Spinacia oleracea) [54304] (1)
                9. Pseudomonas putida, putidaredoxin [54307] (2)
          2. 2Fe-2S ferredoxin domains from multidomain proteins [54312] (1)
             1. Phthalate dioxygenase reductase, C-terminal domain [54323]
                1. Pseudomonas cepacia, db01 [54324] (1)
       3. Staphylokinase/streptokinase [54328] (1)
          1. Staphylokinase/streptokinase [54329] (1)
             1. Staphylokinase [54330]
                1. Staphylococcus aureus [54331] (2)
       4. Superantigen toxins, C-terminal domain [54334] (1)
          1. Superantigen toxins, C-terminal domain [54335] (4)
             1. Staphylococcal enterotoxin C2, SEC2 [54338]
                1. Staphylococcus aureus [54339] (2)
             2. Toxic shock syndrome toxin-1 (TSST-1) [54340]
                1. Staphylococcus aureus [54341] (2)
             3. Staphylococcal enterotoxin B, SEB [54342]
                1. Staphylococcus aureus [54343] (3)
             4. Streptococcal superantigen Spe-C [54348]
                1. Streptococcus pyogenes [54349] (1)
       5. Immunoglobulin-binding domains [54358] (1)
          1. Immunoglobulin-binding domains [54359] (2)
             1. Immunoglobulin-binding protein G, different constituent domains [54360]
                1. Streptococcus sp., group G [54361] (10)
             2. Immunoglobulin light chain-binding domain of protein L [54362]
                1. Peptostreptococcus magnus [54363] (1)
       6. Translation initiation factor IF3, N-terminal domain [54364] (1)
          1. Translation initiation factor IF3, N-terminal domain [54365] (1)
             1. Translation initiation factor IF3, N-terminal domain [54366]
                1. Bacillus stearothermophilus [54367] (1)
       7. Glutamine synthetase, N-terminal domain [54368] (1)
          1. Glutamine synthetase, N-terminal domain [54369] (1)
             1. Glutamine synthetase, N-terminal domain [54370]
                1. Salmonella typhimurium [54371] (1)
   12. FAD-linked reductases, C-terminal domain [54372] (1)
       1. FAD-linked reductases, C-terminal domain [54373] (3)
          1. GMC oxidoreductases [54374] (2)
             1. Cholesterol oxidase [54375]
                1. Brevibacterium sterolicum [54376] (2)
             2. Glucose oxidase [54391]
                1. Aspergillus niger [54392] (1)
          2. PHBH-like [54378] (2)
             1. p-Hydroxybenzoate hydroxylase (PHBH) [54379]
                1. Pseudomonas fluorescens [54380] (11)
                2. Pseudomonas aeruginosa [54381] (13)
          3. GDI-like [54399] (1)
             1. Guanine nucleotide dissociation inhibitor, GDI [54400]
                1. Cow (Bos taurus) [54401] (1)
   13. Cystatin-like [54402] (3)
       1. Cystatin/monellin [54403] (2)
          1. Monellin [54404] (1)
             1. Monellin, B & A chains together [54405]
                1. Serendipity berry (Dioscoreophyllum cumminsii) [54406] (1)
          2. Cystatins [54407] (2)
             1. Cystatin [54410]
                1. Chicken (Gallus gallus) [54411] (2)
             2. Cystatin A (stefin A) [54412]
                1. Human (Homo sapiens) [54413] (4)
       2. Amine oxidase N-terminal region [54416] (1)
          1. Amine oxidase N-terminal region [54417] (1)
             1. Copper amine oxidase, domains 1 and 2 [54418]
                1. Arthrobacter globiformis [54421] (6)
       3. NTF2-like [54427] (2)
          1. Scytalone dehydratase [54428] (1)
             1. Scytalone dehydratase [54429]
                1. Fungus (Magnaporthe grisea) [54430] (2)
          2. Delta-5-3-ketosteroid isomerase, steroid delta-isomerase, KSI [54434] (2)
             1. Delta-5-3-ketosteroid isomerase, steroid delta-isomerase, KSI [54435]
                1. Comamonas testosteroni and Pseudomonas testosteroni [54436] (1)
                2. Pseudomonas putida [54437] (1)
   14. UBC-like [54494] (1)
       1. UBC-like [54495] (1)
          1. Ubiquitin conjugating enzyme, UBC [54496] (4)
             1. Ubiquitin conjugating enzyme, UBC [54497]
                1. Arabidopsis thaliana [54498] (1)
                2. Baker's yeast (Saccharomyces cerevisiae), ubc7 [54501] (1)
                3. Human (Homo sapiens), ubc9 [54503] (2)
                4. Clam (Spisula solidissima), E-2C [54504] (1)
   15. GFP-like [54510] (1)
       1. GFP-like [54511] (1)
          1. Fluorescent proteins [54512] (1)
             1. Green fluorescent protein, GFP [54513]
                1. Jellyfish (Aequorea victoria) [54514] (11)
   16. Pili subunits [54522] (1)
       1. Pili subunits [54523] (1)
          1. Pilin [54524] (1)
             1. Pilin Gc [109618]
                1. Neisseria gonorrhoeae [54526] (2)
   17. FKBP-like [54533] (2)
       1. FKBP-like [54534] (2)
          1. FKBP immunophilin/proline isomerase [54535] (5)
             1. FK-506 binding protein (FKBP12), an immunophilin [54536]
                1. Human (Homo sapiens) [54537] (11)
                2. Cow (Bos taurus) [54538] (2)
             2. Calcineurin (FKBP12.6) [54539]
                1. Baker's yeast (Saccharomyces cerevisiae) [54542] (1)
             3. FKBP25 [54543]
                1. Human (Homo sapiens) [54544] (1)
             4. FKBP59-I, N-terminal domain [54545]
                1. Rabbit (Oryctolagus cuniculus) [54546] (2)
          2. GreA transcript cleavage factor, C-terminal domain [54549] (1)
             1. GreA transcript cleavage factor, C-terminal domain [54550]
                1. Escherichia coli [54551] (1)
       2. Chitinase insertion domain [54556] (1)
          1. Chitinase insertion domain [54557] (1)
             1. Chitinase A [54558]
                1. Serratia marcescens [54559] (1)
   18. Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54592] (1)
       1. Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54593] (1)
          1. Extradiol dioxygenases [54602] (2)
             1. 2,3-Dihydroxybiphenyl dioxygenase (DHBD, BPHC enzyme) [54603]
                1. Pseudomonas sp. [54604] (2)
                2. Burkholderia cepacia (formerly Pseudomonas cepacia) [54605] (2)
   19. beta-hairpin-alpha-hairpin repeat [74651] (1)
       1. Ankyrin repeat [48403] (1)
          1. Ankyrin repeat [48404] (4)
             1. Cell cycle inhibitor p19ink4D [48409]
                1. Human (Homo sapiens) [48410] (1)
             2. Cell cycle inhibitor p16ink4A [48414]
                1. Human (Homo sapiens) [48415] (2)
                2. Mouse (Mus musculus) [48416] (1)
             3. Myotrophin [48419]
                1. Rat (Rattus norvegicus) [48420] (2)
   20. DNA-binding domain of Mlu1-box binding protein MBP1 [54615] (1)
       1. DNA-binding domain of Mlu1-box binding protein MBP1 [54616] (1)
          1. DNA-binding domain of Mlu1-box binding protein MBP1 [54617] (1)
             1. DNA-binding domain of Mlu1-box binding protein MBP1 [54618]
                1. Baker's yeast (Saccharomyces cerevisiae) [54619] (2)
   21. CI-2 family of serine protease inhibitors [54653] (1)
       1. CI-2 family of serine protease inhibitors [54654] (1)
          1. CI-2 family of serine protease inhibitors [54655] (3)
             1. Eglin C [54656]
                1. Leech (Hirudo medicinalis) [54657] (1)
             2. Chymotrypsin inhibitor CI-2 [54658]
                1. Barley (Hordeum vulgare) [54659] (1)
             3. Trypsin inhibitor V [54660]
                1. Pumpkin (Cucurbita maxima) [54661] (2)
   22. alpha/beta-Hammerhead [54664] (1)
       1. Pyrimidine nucleoside phosphorylase C-terminal domain [54680] (1)
          1. Pyrimidine nucleoside phosphorylase C-terminal domain [54681] (1)
             1. Thymidine phosphorylase [54682]
                1. Escherichia coli [54683] (3)
   23. POZ domain [54694] (1)
       1. POZ domain [54695] (1)
          1. Tetramerization domain of potassium channels [54701] (2)
             1. Shaker potassium channel [54702]
                1. California sea hare (Aplysia californica) [54703] (1)
             2. akv3.1 voltage-gated potassium channel [54704]
                1. California sea hare (Aplysia californica) [54705] (1)
   24. EF-Ts domain-like [54712] (1)
       1. Elongation factor Ts (EF-Ts), dimerisation domain [54713] (1)
          1. Elongation factor Ts (EF-Ts), dimerisation domain [54714] (1)
             1. Elongation factor Ts (EF-Ts), dimerisation domain [63422]
                1. Thermus thermophilus [54717] (1)
   25. ClpS-like [54735] (1)
       1. ClpS-like [54736] (1)
          1. Ribosomal protein L7/12, C-terminal domain [54737] (1)
             1. Ribosomal protein L7/12, C-terminal domain [54738]
                1. Escherichia coli [54739] (1)
   26. Anti-LPS factor/recA domain [54751] (1)
       1. RecA protein, C-terminal domain [54752] (1)
          1. RecA protein, C-terminal domain [54753] (1)
             1. RecA protein, C-terminal domain [54754]
                1. Escherichia coli [54755] (3)
   27. Signal recognition particle alu RNA binding heterodimer, SRP9/14 [54761] (1)
       1. Signal recognition particle alu RNA binding heterodimer, SRP9/14 [54762] (1)
          1. Signal recognition particle alu RNA binding heterodimer, SRP9/14 [54763] (2)
             1. Signal recognition particle 9KDa protein, SRP9 [88845]
                1. Mouse (Mus musculus) [88847] (1)
             2. Signal recognition particle 14KDa protein, SRP14 [88848]
                1. Mouse (Mus musculus) [88850] (1)
   28. dsRBD-like [54767] (2)
       1. dsRNA-binding domain-like [54768] (2)
          1. Double-stranded RNA-binding domain (dsRBD) [54769] (1)
             1. Staufen, domain III [54772]
                1. Fruit fly (Drosophila melanogaster) [54773] (1)
          2. Ribosomal S5 protein, N-terminal domain [54778] (1)
             1. Ribosomal S5 protein, N-terminal domain [54779]
                1. Bacillus stearothermophilus [54780] (1)
       2. Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain [54782] (1)
          1. Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain [54783] (1)
             1. Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain [54784]
                1. Escherichia coli [54785] (3)
   29. Eukaryotic type KH-domain (KH-domain type I) [54790] (1)
       1. Eukaryotic type KH-domain (KH-domain type I) [54791] (1)
          1. Eukaryotic type KH-domain (KH-domain type I) [54792] (2)
             1. Vigilin, KH6 [54797]
                1. Human (Homo sapiens) [54798] (2)
             2. Fragile X protein, KH1 [54799]
                1. Human (Homo sapiens) [54800] (1)
   30. Nucleotidyltransferase [81302] (1)
       1. Nucleotidyltransferase [81301] (1)
          1. DNA polymerase beta-like [81300] (1)
             1. DNA polymerase beta, catalytic (31 kD) fragment [81578]
                1. Rat (Rattus norvegicus) [81576] (12)
   31. Enolase N-terminal domain-like [54825] (1)
       1. Enolase N-terminal domain-like [54826] (1)
          1. Enolase N-terminal domain-like [54827] (5)
             1. Enolase [54828]
                1. Baker's yeast (Saccharomyces cerevisiae) [54829] (7)
                2. Lobster (Homarus vulgaris) [54830] (2)
             2. D-glucarate dehydratase [54831]
                1. Pseudomonas putida [54832] (1)
             3. Mandelate racemase [54838]
                1. Pseudomonas putida [54839] (6)
             4. Chlormuconate cycloisomerase [54840]
                1. Alcaligenes eutrophus [54841] (1)
   32. GroEL-intermediate domain like [54848] (1)
       1. GroEL-intermediate domain like [54849] (1)
          1. GroEL-like chaperone, intermediate domain [54850] (1)
             1. GroEL, I domain [54851]
                1. Escherichia coli [54852] (1)
   33. Ferredoxin-like [54861] (17)
       1. 4Fe-4S ferredoxins [54862] (4)
          1. Short-chain ferredoxins [54863] (3)
             1. Ferredoxin II [54864]
                1. Clostridium acidi-urici [54867] (3)
                2. Clostridium pasteurianum [54868] (1)
                3. Chromatium vinosum [54869] (1)
          2. 7-Fe ferredoxin [54870] (2)
             1. Ferredoxin [54871]
                1. Azotobacter vinelandii [54872] (17)
                2. Bacillus schlegelii [54873] (2)
          3. Archaeal ferredoxins [54874] (1)
             1. Ferredoxin [54875]
                1. Archaeon Sulfolobus sp. [54876] (1)
          4. Single 4Fe-4S cluster ferredoxin [54877] (3)
             1. Ferredoxin A [54878]
                1. Thermotoga maritima [54879] (2)
             2. Ferredoxin I [54880]
                1. Sulfate-reducing bacteria (Desulfovibrio africanus) [54881] (2)
                2. Desulfovibrio gigas [54865] (2)
       2. Protease propeptides/inhibitors [54897] (1)
          1. Pancreatic carboxypeptidase, activation domain [54898] (3)
             1. Procarboxypeptidase A [54899]
                1. Pig (Sus scrofa) [54900] (1)
                2. Human (Homo sapiens) [54902] (1)
             2. Procarboxypeptidase B [54903]
                1. Pig (Sus scrofa) [54904] (2)
       3. Dimeric alpha+beta barrel [54909] (1)
          1. Muconalactone isomerase, MLI [54910] (1)
             1. Muconalactone isomerase, MLI [54911]
                1. Pseudomonas putida [54912] (1)
       4. GlnB-like [54913] (1)
          1. Prokaryotic signal transducing protein [54914] (1)
             1. PII (product of glnB) [54915]
                1. Escherichia coli [54916] (2)
       5. Nucleoside diphosphate kinase, NDK [54919] (1)
          1. Nucleoside diphosphate kinase, NDK [54920] (1)
             1. Nucleoside diphosphate kinase, NDK [54921]
                1. Dictyostelium discoideum [54925] (6)
       6. RNA-binding domain, RBD [54928] (1)
          1. Canonical RBD [54929] (3)
             1. Nuclear ribonucleoprotein A1 (RNP A1, UP1) [54930]
                1. Human (Homo sapiens) [54931] (4)
             2. Splicesomal U1A protein [54932]
                1. Human (Homo sapiens) [54933] (2)
             3. Sex-lethal protein [54938]
                1. Drosophila melanogaster [54939] (2)
       7. Viral DNA-binding domain [54957] (1)
          1. Viral DNA-binding domain [54958] (1)
             1. Papillomavirus-1 E2 protein [54959]
                1. Human papillomavirus type 16 [54962] (1)
       8. Acylphosphatase-like [54975] (1)
          1. Acylphosphatase-like [54976] (2)
             1. Acylphosphatase [54977]
                1. Cow (Bos taurus) [54978] (1)
                2. Horse (Equus caballus) [54979] (1)
       9. EF-G C-terminal domain-like [54980] (1)
          1. EF-G/eEF-2 domains III and V [54981] (1)
             1. Elongation factor G (EF-G) [54982]
                1. Thermus thermophilus [54983] (2)
       10. eEF-1beta-like [54984] (1)
           1. eEF-1beta-like [54985] (1)
              1. Guanine nucleotide exchange factor (GEF) domain from elongation factor-1 beta [54986]
                 1. Human (Homo sapiens) [54987] (1)
       11. Ribosomal protein S6 [54995] (1)
           1. Ribosomal protein S6 [54996] (1)
              1. Ribosomal protein S6 [54997]
                 1. Thermus thermophilus [54998] (1)
       12. HMA, heavy metal-associated domain [55008] (1)
           1. HMA, heavy metal-associated domain [55009] (2)
              1. Mercuric ion binding protein MerP [55010]
                 1. Shigella flexneri [55011] (3)
              2. Menkes copper-transporting ATPase [55012]
                 1. Human (Homo sapiens) [55013] (2)
       13. ACT-like [55021] (1)
           1. Allosteric threonine deaminase C-terminal domain [55025] (1)
              1. Allosteric threonine deaminase C-terminal domain [55026]
                 1. Escherichia coli [55027] (2)
       14. Probable ACP-binding domain of malonyl-CoA ACP transacylase [55048] (1)
           1. Probable ACP-binding domain of malonyl-CoA ACP transacylase [55049] (1)
              1. Probable ACP-binding domain of malonyl-CoA ACP transacylase [55050]
                 1. Escherichia coli [55051] (1)
       15. CheY-binding domain of CheA [55052] (1)
           1. CheY-binding domain of CheA [55053] (1)
              1. CheY-binding domain of CheA [55054]
                 1. Escherichia coli [55055] (1)
       16. 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK [55083] (1)
           1. 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK [55084] (1)
              1. 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK [55085]
                 1. Escherichia coli [55086] (1)
       17. Sulfite reductase, domains 1 and 3 [55124] (1)
           1. Sulfite reductase, domains 1 and 3 [55125] (1)
              1. Sulfite reductase, domains 1 and 3 [55126]
                 1. Escherichia coli [55127] (24)
   34. eIF1-like [55158] (1)
       1. eIF1-like [55159] (1)
          1. eIF1-like [55160] (1)
             1. Eukaryotic translation initiation factor eIF-1 (SUI1) [55161]
                1. Human (Homo sapiens) [55162] (1)
   35. Hedgehog/DD-peptidase [55165] (1)
       1. Hedgehog/DD-peptidase [55166] (2)
          1. Muramoyl-pentapeptide carboxypeptidase [55167] (1)
             1. Zn2+ DD-carboxypeptidase C-terminal catalytic domain [55168]
                1. Streptomyces albus G [55169] (1)
          2. Hedgehog (development protein), N-terminal signaling domain [55170] (1)
             1. Sonic hedgehog [55171]
                1. Mouse (Mus musculus) [55172] (1)
   36. IF3-like [55199] (2)
       1. Translation initiation factor IF3, C-terminal domain [55200] (1)
          1. Translation initiation factor IF3, C-terminal domain [55201] (1)
             1. Translation initiation factor IF3, C-terminal domain [55202]
                1. Bacillus stearothermophilus [55203] (1)
       2. EPT/RTPC-like [55205] (1)
          1. Enolpyruvate transferase, EPT [55209] (2)
             1. UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ) [55210]
                1. Escherichia coli [55211] (2)
             2. 5-enol-pyruvyl shikimate-3-phosphate (EPSP) synthase [55213]
                1. Escherichia coli [55214] (1)
   37. Bacillus chorismate mutase-like [55297] (1)
       1. Tubulin C-terminal domain-like [55307] (1)
          1. Tubulin, C-terminal domain [55308] (1)
             1. Cell-division protein FtsZ [55309]
                1. Archaeon Methanococcus jannaschii [55310] (1)
   38. Tautomerase/MIF [55330] (1)
       1. Tautomerase/MIF [55331] (1)
          1. MIF-related [55339] (1)
             1. Microphage migration inhibition factor (MIF) [55340]
                1. Rat (Rattus norvegicus) [55342] (1)
   39. Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain [55346] (1)
       1. Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain [55347] (2)
          1. Dihydrodipicolinate reductase-like [55368] (2)
             1. Diaminopimelic acid dehydrogenase (DAPDH) [55369]
                1. Corynebacterium glutamicum [55370] (1)
             2. Dihydrodipicolinate reductase [55371]
                1. Escherichia coli [55372] (4)
          2. Glucose 6-phosphate dehydrogenase-like [55376] (1)
             1. Glucose 6-phosphate dehydrogenase [55379]
                1. Leuconostoc mesenteroides [55380] (1)
   40. Aha1/BPI domain-like [55393] (1)
       1. Bactericidal permeability-increasing protein, BPI [55394] (1)
          1. Bactericidal permeability-increasing protein, BPI [55395] (1)
             1. Bactericidal permeability-increasing protein, BPI [55396]
                1. Human (Homo sapiens) [55397] (2)
   41. Subtilisin inhibitor [55398] (1)
       1. Subtilisin inhibitor [55399] (1)
          1. Subtilisin inhibitor [55400] (1)
             1. Subtilisin inhibitor [55401]
                1. Streptomyces albogriseolus, s-3253 [55403] (1)
   42. RNA bacteriophage capsid protein [55404] (1)
       1. RNA bacteriophage capsid protein [55405] (1)
          1. RNA bacteriophage capsid protein [55406] (1)
             1. MS2 virus coat protein [55407]
                1. Bacteriophage MS2 [55408] (1)
   43. Translation initiation factor eIF4e [55417] (1)
       1. Translation initiation factor eIF4e [55418] (1)
          1. Translation initiation factor eIF4e [55419] (1)
             1. Translation initiation factor eIF4e [55420]
                1. Baker's yeast (Saccharomyces cerevisiae) [55422] (1)
   44. CO dehydrogenase flavoprotein C-domain-like [55423] (1)
       1. FAD/NAD-linked reductases, dimerisation (C-terminal) domain [55424] (1)
          1. FAD/NAD-linked reductases, dimerisation (C-terminal) domain [55425] (5)
             1. Glutathione reductase [55426]
                1. Human (Homo sapiens) [55427] (15)
             2. NADH peroxidase [55432]
                1. Enterococcus faecalis [55433] (7)
             3. Dihydrolipoamide dehydrogenase [55436]
                1. Pseudomonas putida [55437] (1)
                2. Neisseria meningitidis [55441] (2)
             4. NADH oxidase /nitrite reductase [118042]
                1. Pyrococcus furiosus [118043] (1)
   45. Origin of replication-binding domain, RBD-like [55463] (1)
       1. Origin of replication-binding domain, RBD-like [55464] (1)
          1. The origin DNA-binding domain of SV40 T-antigen [55465] (1)
             1. The origin DNA-binding domain of SV40 T-antigen [55466]
                1. Simian virus 40, Sv40 [55467] (2)
   46. FMN-dependent nitroreductase-like [55468] (1)
       1. FMN-dependent nitroreductase-like [55469] (1)
          1. NADH oxidase/flavin reductase [55470] (1)
             1. NADH oxidase [55471]
                1. Thermus thermophilus, HB8 [55472] (1)
   47. Zincin-like [55485] (2)
       1. Metalloproteases ("zincins"), catalytic domain [55486] (7)
          1. Zinc protease [55487] (1)
             1. Zinc protease [55488]
                1. Streptomyces caespitosus [55489] (1)
          2. Thermolysin-like [55490] (3)
             1. Elastase [63413]
                1. Pseudomonas aeruginosa [55492] (1)
             2. Thermolysin [63414]
                1. Bacillus thermoproteolyticus [55494] (5)
             3. Neutral protease [63415]
                1. Bacillus cereus, strain dsm 3101 [55496] (2)
          3. Leishmanolysin [55499] (1)
             1. Leishmanolysin [55500]
                1. Leishmania major [55501] (1)
          4. Serralysin-like metalloprotease, catalytic (N-terminal) domain [55508] (2)
             1. Metalloprotease [55509]
                1. Pseudomonas aeruginosa [55510] (1)
                2. Serratia marcescens [55511] (2)
          5. Astacin [55516] (1)
             1. Astacin [55517]
                1. European fresh water crayfish (Astacus astacus) [55518] (6)
          6. Reprolysin-like [55519] (1)
             1. Snake venom metalloprotease [55520]
                1. Eastern diamondback rattlesnake (Crotalus adamanteus), adamalysin II [55521] (3)
          7. Matrix metalloproteases, catalytic domain [55528] (5)
             1. Fibroblast collagenase (MMP-1) [55529]
                1. Human (Homo sapiens) [55530] (6)
                2. Pig (Sus scrofa) [55531] (1)
             2. Neutrophil collagenase (MMP-8) [55532]
                1. Human (Homo sapiens) [55533] (2)
             3. Stromelysin-1 (MMP-3) [55536]
                1. Human (Homo sapiens), fibroblast [55537] (8)
             4. Matrilysin (MMP-7) [55538]
                1. Human (Homo sapiens) [55539] (2)
       2. beta-N-acetylhexosaminidase-like domain [55545] (1)
          1. beta-N-acetylhexosaminidase domain [55546] (1)
             1. Bacterial chitobiase, Domain 2 [55547]
                1. Serratia marcescens [55548] (2)
   48. SH2-like [55549] (1)
       1. SH2 domain [55550] (1)
          1. SH2 domain [55551] (11)
             1. c-src tyrosine kinase [55556]
                1. Human (Homo sapiens) [55557] (2)
                2. Chicken (Gallus gallus) [55558] (1)
                3. Rous sarcoma virus [69782] (3)
             2. Tyrosine phosphatase Syp [55561]
                1. Mouse (Mus musculus) [55562] (1)
             3. Growth factor receptor-bound protein 2 (GRB2) [55563]
                1. Human (Homo sapiens) [55564] (2)
             4. Hemopoetic cell kinase Hck [55565]
                1. Human (Homo sapiens) [55566] (1)
             5. Shc adaptor protein [55567]
                1. Human (Homo sapiens) [55568] (1)
             6. Phosphatidylinositol 3-kinase, p85-alpha subunit [55569]
                1. Cow (Bos taurus) [55570] (4)
             7. Proto-oncogen tyrosine kinase [55573]
                1. Human (Homo sapiens) [55574] (1)
             8. P55 Blk protein tyrosine kinase [55579]
                1. Mouse (Mus musculus) [55580] (2)
             9. Abl tyrosine kinase [55581]
                1. Human (Homo sapiens) [55582] (1)
   49. HPr-like [55593] (1)
       1. HPr-like [55594] (1)
          1. HPr-like [55595] (4)
             1. Histidine-containing phosphocarrier protein (HPr) [55596]
                1. Bacillus subtilis [55597] (3)
                2. Enterococcus faecalis [55598] (1)
                3. Escherichia coli [55599] (4)
                4. Mycoplasma capricolum [55600] (1)
   50. Homing endonuclease-like [55603] (2)
       1. Glucose permease domain IIB [55604] (1)
          1. Glucose permease domain IIB [55605] (1)
             1. Glucose permease domain IIB [55606]
                1. Escherichia coli [55607] (1)
       2. Homing endonucleases [55608] (1)
          1. Group I mobile intron endonuclease [55609] (1)
             1. DNA endonuclease I-CreI [55610]
                1. Chlamydomonas reinhardtii [55611] (1)
   51. T-fold [55619] (1)
       1. Tetrahydrobiopterin biosynthesis enzymes-like [55620] (1)
          1. DHN aldolase/epimerase [55628] (1)
             1. 7,8-dihydroneopterin aldolase [55629]
                1. Staphylococcus aureus [55630] (2)
   52. Cell cycle regulatory proteins [55636] (1)
       1. Cell cycle regulatory proteins [55637] (1)
          1. Cell cycle regulatory proteins [55638] (1)
             1. suc1 [55639]
                1. Fission yeast (Schizosaccharomyces pombe) [55640] (1)
   53. Ribosomal protein L9 C-domain [55652] (1)
       1. Ribosomal protein L9 C-domain [55653] (1)
          1. Ribosomal protein L9 C-domain [55654] (1)
             1. Ribosomal protein L9 C-domain [55655]
                1. Bacillus stearothermophilus [55656] (1)
   54. L9 N-domain-like [55657] (1)
       1. L9 N-domain-like [55658] (1)
          1. Ribosomal protein L9 N-domain [55659] (1)
             1. Ribosomal protein L9 N-domain [55660]
                1. Bacillus stearothermophilus [55661] (1)
   55. Regulatory factor Nef [55670] (1)
       1. Regulatory factor Nef [55671] (1)
          1. Regulatory factor Nef [55672] (1)
             1. Regulatory factor Nef [55673]
                1. Human immunodeficiency virus type 1 [55674] (2)
   56. CytB endotoxin-like [55675] (1)
       1. CytB endotoxin-like [55676] (1)
          1. CytB endotoxin-like [55677] (1)
             1. Mosquitocidal delta-endotoxin CytB [55678]
                1. Bacillus thuringiensis, strain Kyushuensis [55679] (1)
   57. Class II aaRS and biotin synthetases [55680] (1)
       1. Class II aaRS and biotin synthetases [55681] (1)
          1. Biotin holoenzyme synthetase [55707] (1)
             1. Biotin repressor/biotin holoenzyme synthetase, catalytic (central) domain [55708]
                1. Escherichia coli [55709] (2)
   58. Acyl-CoA N-acyltransferases (Nat) [55728] (1)
       1. Acyl-CoA N-acyltransferases (Nat) [55729] (1)
          1. N-acetyl transferase, NAT [55730] (1)
             1. Histone acetyltransferase HAT1 [55742]
                1. Baker's yeast (Saccharomyces cerevisiae) [55743] (1)
   59. Gelsolin-like [55752] (1)
       1. Actin depolymerizing proteins [55753] (2)
          1. Gelsolin-like [55754] (2)
             1. Villin, domain 1 (res. 1-126) [55755]
                1. Chicken (Gallus gallus) [55756] (2)
             2. Severin, domain 2 [55757]
                1. Dictyostelium discoideum [55758] (3)
          2. Cofilin-like [55762] (3)
             1. Cofilin (actin depolymerizing factor, ADF) [55763]
                1. Baker's yeast (Saccharomyces cerevisiae) [55765] (1)
                2. Amoeba (Acanthamoeba castellanii), actophorin [55766] (1)
             2. Destrin [55767]
                1. Human and pig (Homo sapiens) and (Sus scrofa) [55768] (2)
   60. Profilin-like [55769] (2)
       1. Profilin (actin-binding protein) [55770] (1)
          1. Profilin (actin-binding protein) [55771] (5)
             1. Profilin (actin-binding protein) [55772]
                1. Cow (Bos taurus) [55773] (1)
                2. Human (Homo sapiens), isoform I [55774] (3)
                3. Acanthamoeba castellanii [55776] (4)
                4. Birch (Betula verrucosa) [55778] (1)
                5. Mouse-ear cress (Arabidopsis thaliana) [55779] (2)
       2. PYP-like sensor domain (PAS domain) [55785] (1)
          1. PYP-like [55786] (1)
             1. Photoactive yellow protein, PYP [55787]
                1. Ectothiorhodospira halophila [55788] (5)
   61. PR-1-like [55796] (1)
       1. PR-1-like [55797] (1)
          1. PR-1-like [55798] (1)
             1. Pathogenesis-related protein 1 (PR1) [55799]
                1. Tomato (Lycopersicon esculentum), P14a [55800] (1)
   62. Nudix [55810] (1)
       1. Nudix [55811] (1)
          1. MutT-like [55812] (1)
             1. Nucleoside triphosphate pyrophosphorylase (MutT) [55813]
                1. Escherichia coli [55814] (2)
   63. 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain [55815] (1)
       1. 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain [55816] (1)
          1. 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain [55817] (1)
             1. 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain [55818]
                1. Escherichia coli [55819] (1)
   64. Thymidylate synthase/dCMP hydroxymethylase [55830] (1)
       1. Thymidylate synthase/dCMP hydroxymethylase [55831] (1)
          1. Thymidylate synthase/dCMP hydroxymethylase [55832] (3)
             1. Thymidylate synthase [55833]
                1. Escherichia coli [55834] (11)
                2. Lactobacillus casei [55835] (34)
                3. Bacteriophage T4 [55837] (1)
   65. N-acetylmuramoyl-L-alanine amidase-like [55845] (1)
       1. N-acetylmuramoyl-L-alanine amidase-like [55846] (1)
          1. N-acetylmuramoyl-L-alanine amidase-like [55847] (1)
             1. Bacteriophage T7 lysozyme (Zn amidase) [55848]
                1. Bacteriophage T7 [55849] (1)
   66. Cytochrome b5-like heme/steroid binding domain [55855] (1)
       1. Cytochrome b5-like heme/steroid binding domain [55856] (1)
          1. Cytochrome b5 [55857] (2)
             1. Cytochrome b5 [55858]
                1. Cow (Bos taurus) [55859] (1)
                2. Rat (Rattus norvegicus) [55860] (10)
   67. DNA topoisomerase I domain [55868] (1)
       1. DNA topoisomerase I domain [55869] (1)
          1. Vaccinia DNA topoisomerase I, 9 kDa N-terminal fragment [55870] (1)
             1. Vaccinia DNA topoisomerase I, 9 kDa N-terminal fragment [55871]
                1. Vaccinia virus, strain WR [55872] (1)
   68. ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1)
       1. ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (2)
          1. Heat shock protein 90, HSP90, N-terminal domain [55875] (2)
             1. HSP90 [55876]
                1. Baker's yeast (Saccharomyces cerevisiae) [55877] (5)
                2. Human (Homo sapiens) [55878] (3)
          2. DNA gyrase/MutL, N-terminal domain [55879] (1)
             1. DNA gyrase B [55880]
                1. Escherichia coli [55881] (1)
   69. Pentein, beta/alpha-propeller [55908] (1)
       1. Pentein [55909] (1)
          1. Amidinotransferase [55914] (1)
             1. L-arginine: glycine amidinotransferase [55915]
                1. Human (Homo sapiens) [55916] (3)
   70. Creatinase/aminopeptidase [55919] (1)
       1. Creatinase/aminopeptidase [55920] (1)
          1. Creatinase/aminopeptidase [55921] (4)
             1. Methionine aminopeptidase [55924]
                1. Escherichia coli [55925] (1)
                2. Archaeon Pyrococcus furiosus [55926] (1)
                3. Human (Homo sapiens) [55927] (3)
             2. Aminopeptidase P, C-terminal domain [55928]
                1. Escherichia coli [55929] (2)
   71. Glutamine synthetase/guanido kinase [55930] (1)
       1. Glutamine synthetase/guanido kinase [55931] (2)
          1. Glutamine synthetase catalytic domain [55932] (1)
             1. Glutamine synthetase, C-terminal domain [55933]
                1. Salmonella typhimurium [55934] (1)
          2. Guanido kinase catalytic domain [55935] (1)
             1. Arginine kinase, C-terminal domain [55942]
                1. Horseshoe crab (Limulus polyphemus) [55943] (1)
   72. TBP-like [55944] (1)
       1. Bet v1-like [55961] (1)
          1. Pathogenesis-related protein 10 (PR10)-like [55962] (1)
             1. Major tree pollen allergen [55963]
                1. White birch (Betula verrucosa), Bet v 1 [55964] (2)
   73. S-adenosylmethionine synthetase [55972] (1)
       1. S-adenosylmethionine synthetase [55973] (1)
          1. S-adenosylmethionine synthetase [55974] (1)
             1. S-adenosylmethionine synthetase [55975]
                1. Escherichia coli [55976] (18)
   74. DNA clamp [55978] (1)
       1. DNA clamp [55979] (1)
          1. DNA polymerase processivity factor [55983] (1)
             1. Proliferating cell nuclear antigen (PCNA) [55989]
                1. Baker's yeast (Saccharomyces cerevisiae) [55990] (4)
   75. Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 [56013] (1)
       1. Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 [56014] (1)
          1. Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 [56015] (1)
             1. Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 [56016]
                1. Escherichia coli [56017] (24)
   76. Monooxygenase (hydroxylase) regulatory protein [56028] (1)
       1. Monooxygenase (hydroxylase) regulatory protein [56029] (1)
          1. Monooxygenase (hydroxylase) regulatory protein [56030] (2)
             1. Soluble methane monooxygenase regulatory protein B [56031]
                1. Escherichia coli [56032] (1)
             2. Phenol hydroxylase P2 protein [56034]
                1. Pseudomonas sp., CF600 [56035] (1)
   77. ATP-grasp [56058] (2)
       1. Glutathione synthetase ATP-binding domain-like [56059] (2)
          1. ATP-binding domain of peptide synthetases [56060] (2)
             1. Prokaryotic glutathione synthetase, C-domain [56061]
                1. Escherichia coli [56062] (4)
             2. D-ala-D-ala ligase, C-domain [56063]
                1. Escherichia coli, gene ddlB [56064] (3)
          2. Pyruvate phosphate dikinase, N-terminal domain [56085] (1)
             1. Pyruvate phosphate dikinase, N-terminal domain [56086]
                1. Clostridium symbiosum [56087] (1)
       2. DNA ligase/mRNA capping enzyme, catalytic domain [56091] (2)
          1. ATP-dependent DNA ligase catalytic domain [56092] (1)
             1. ATP-dependent DNA ligase, N-terminal domain [56093]
                1. Bacteriophage T7 [56094] (1)
          2. mRNA capping enzyme [56100] (1)
             1. RNA guanylyltransferase (mRNA capping enzyme), N-terminal domain [56101]
                1. Chlorella virus, PBCV-1 [56102] (1)
   78. SAICAR synthase-like [56103] (1)
       1. SAICAR synthase-like [56104] (1)
          1. SAICAR synthase [56105] (1)
             1. SAICAR synthase [56106]
                1. Baker's yeast (Saccharomyces cerevisiae) [56107] (1)
   79. Protein kinase-like (PK-like) [56111] (1)
       1. Protein kinase-like (PK-like) [56112] (1)
          1. Protein kinases, catalytic subunit [88854] (15)
             1. Cyclin-dependent PK, CDK2 [88855]
                1. Human (Homo sapiens) [88856] (3)
             2. MAP kinase p38 [56129]
                1. Human (Homo sapiens) [56130] (3)
                2. Mouse (Mus musculus) [56131] (1)
             3. MAP kinase Erk2 [56134]
                1. Human (Homo sapiens) [56135] (1)
                2. Rat (Rattus norvegicus) [56136] (5)
             4. c-jun N-terminal kinase (jnk3s) [56137]
                1. Human (Homo sapiens) [56138] (1)
             5. cAMP-dependent PK, catalytic subunit [56116]
                1. Mouse (Mus musculus) [56119] (1)
             6. Calmodulin-dependent protein kinase [56120]
                1. Rat (Rattus norvegicus) [56121] (1)
             7. Twitchin, kinase domain [56126]
                1. Caenorhabditis elegans, pjk4 [56128] (1)
             8. gamma-subunit of glycogen phosphorylase kinase (Phk) [56122]
                1. Rabbit (Oryctolagus cuniculus) [56123] (1)
             9. Casein kinase-1, CK1 [56139]
                1. Fission yeast (Schizosaccharomyces pombe) [56141] (2)
             10. c-src tyrosine kinase [56155]
                 1. Human (Homo sapiens) [56156] (2)
                 2. Chicken (Gallus gallus) [56157] (1)
             11. Lymphocyte kinase (lck) [56153]
                 1. Human (Homo sapiens) [56154] (1)
             12. Insulin receptor [56162]
                 1. Human (Homo sapiens) [56163] (1)
   80. FAD-binding domain [56175] (1)
       1. FAD-binding domain [56176] (1)
          1. Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase (MurB), N-terminal domain [56184] (1)
             1. Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase (MurB), N-terminal domain [56185]
                1. Escherichia coli [56186] (4)
   81. Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain [56193] (1)
       1. Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain [56194] (1)
          1. Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain [56195] (1)
             1. Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain [56196]
                1. Escherichia coli [56197] (4)
   82. DNase I-like [56218] (1)
       1. DNase I-like [56219] (1)
          1. DNase I-like [56220] (3)
             1. DNA-repair enzyme exonuclease III [56221]
                1. Escherichia coli [56222] (1)
             2. DNA repair endonuclease Hap1 [56223]
                1. Human (Homo sapiens) [56224] (1)
             3. Deoxyribonuclease I [56225]
                1. Cow (Bos taurus) [56226] (1)
   83. Metallo-hydrolase/oxidoreductase [56280] (1)
       1. Metallo-hydrolase/oxidoreductase [56281] (1)
          1. Zn metallo-beta-lactamase [56282] (1)
             1. Zn metallo-beta-lactamase [56283]
                1. Bacillus cereus [56284] (2)
   84. PP2C-like [81607] (1)
       1. PP2C-like [81606] (1)
          1. PP2C-like [81605] (1)
             1. Protein serine/threonine phosphatase 2C, catalytic domain [81604]
                1. Human (Homo sapiens) [81603] (1)
   85. Metallo-dependent phosphatases [56299] (1)
       1. Metallo-dependent phosphatases [56300] (1)
          1. 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain [56307] (1)
             1. 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain [56308]
                1. Escherichia coli [56309] (1)
   86. LDH C-terminal domain-like [56326] (1)
       1. LDH C-terminal domain-like [56327] (1)
          1. Lactate & malate dehydrogenases, C-terminal domain [56328] (8)
             1. Malate dehydrogenase [56329]
                1. Escherichia coli [56333] (2)
             2. Lactate dehydrogenase [56339]
                1. Pig (Sus scrofa) [56340] (1)
                2. Mouse (Mus musculus) [56341] (1)
                3. Dogfish (Squalus acanthias) [56342] (3)
                4. Malaria parasite (Plasmodium falciparum) [56343] (1)
                5. Bacillus stearothermophilus [56344] (2)
                6. Lactobacillus casei [56345] (1)
                7. Thermotoga maritima [56347] (1)
   87. DNA breaking-rejoining enzymes [56348] (1)
       1. DNA breaking-rejoining enzymes [56349] (2)
          1. Lambda integrase-like, catalytic core [56350] (1)
             1. Recombinase XerD [56357]
                1. Escherichia coli [56358] (1)
          2. Eukaryotic DNA topoisomerase I, catalytic core [56361] (1)
             1. Eukaryotic DNA topoisomerase I, catalytic core [56362]
                1. Vaccinia virus [56364] (1)
   88. Ribosome inactivating proteins (RIP) [56370] (1)
       1. Ribosome inactivating proteins (RIP) [56371] (1)
          1. Plant cytotoxins [56372] (4)
             1. alpha-Trichosanthin [56373]
                1. Mongolian snake gourd (Trichosanthes kirilowii maxim) [56374] (3)
             2. alpha-Momorcharin (momordin) [56377]
                1. Bitter gourd (Momordica charantia) [56378] (7)
             3. Pokeweed antiviral protein alpha [56385]
                1. Pokeweed (Phytolacca americana) [56386] (1)
             4. Ricin A-chain [56389]
                1. Castor bean (Ricinus communis) [56390] (7)
   89. ADP-ribosylation [56398] (1)
       1. ADP-ribosylation [56399] (2)
          1. ADP-ribosylating toxins [56400] (1)
             1. Diphtheria toxin, N-terminal domain [56404]
                1. Corynebacterium diphtheriae [56405] (3)
          2. Poly(ADP-ribose) polymerase, C-terminal domain [56416] (1)
             1. Poly(ADP-ribose) polymerase, C-terminal domain [56417]
                1. Chicken (Gallus gallus) [56418] (6)
   90. Peptide deformylase [56419] (1)
       1. Peptide deformylase [56420] (1)
          1. Peptide deformylase [56421] (1)
             1. Peptide deformylase [56422]
                1. Escherichia coli [56423] (3)
   91. C-type lectin-like [56435] (1)
       1. C-type lectin-like [56436] (2)
          1. C-type lectin domain [56437] (5)
             1. Lithostathine, inhibitor of stone formation [56438]
                1. Human (Homo sapiens) [56439] (1)
             2. CD94 [56440]
                1. Human (Homo sapiens) [56441] (1)
             3. E-selectin, C-lectin domain [56456]
                1. Human (Homo sapiens) [56457] (1)
             4. Mannose-binding protein A, C-lectin domain [56458]
                1. Human (Homo sapiens) [56459] (1)
             5. Tetranectin [56465]
                1. Human (Homo sapiens) [56466] (2)
          2. Endostatin [56480] (1)
             1. Endostatin [56481]
                1. Mouse (Mus musculus) [56483] (1)
   92. SRCR-like [56486] (1)
       1. SRCR-like [56487] (1)
          1. Scavenger receptor cysteine-rich (SRCR) domain [56488] (1)
             1. M2BP [56489]
                1. Human (Homo sapiens) [56490] (1)
   93. Fibrinogen C-terminal domain-like [56495] (1)
       1. Fibrinogen C-terminal domain-like [56496] (1)
          1. Fibrinogen C-terminal domain-like [56497] (1)
             1. Fibrinogen C-terminal domains [56498]
                1. Human (Homo sapiens), gamma [68904] (3)
   94. Methionine synthase activation domain-like [56506] (1)
       1. Methionine synthase activation domain-like [56507] (1)
          1. Methionine synthase SAM-binding domain [56508] (1)
             1. Methionine synthase SAM-binding domain [56509]
                1. Escherichia coli [56510] (1)
   95. Nitric oxide (NO) synthase oxygenase domain [56511] (1)
       1. Nitric oxide (NO) synthase oxygenase domain [56512] (1)
          1. Nitric oxide (NO) synthase oxygenase domain [56513] (1)
             1. Nitric oxide (NO) synthase oxygenase domain [56514]
                1. Mouse (Mus musculus) [56515] (2)
   96. Penicillin binding protein dimerisation domain [56518] (1)
       1. Penicillin binding protein dimerisation domain [56519] (1)
          1. Penicillin binding protein dimerisation domain [56520] (1)
             1. Penicillin-binding protein 2x (pbp-2x), N-terminal domain [56521]
                1. Streptococcus pneumoniae [56522] (1)
   97. Aromatic aminoacid monoxygenases, catalytic and oligomerization domains [56533] (1)
       1. Aromatic aminoacid monoxygenases, catalytic and oligomerization domains [56534] (1)
          1. Aromatic aminoacid monoxygenases, catalytic and oligomerization domains [56535] (2)
             1. Tyrosine hydroxylase [56536]
                1. Rat (Rattus norvegicus) [56537] (1)
             2. Phenylalanine hydroxylase, PAH [56538]
                1. Human (Homo sapiens) [56539] (5)
5. Multi-domain proteins (alpha and beta) [56572] (10)
   Folds consisting of two or more domains belonging to different classes
   1. Serpins [56573] (1)
      1. Serpins [56574] (1)
         1. Serpins [56575] (2)
            1. Antitrypsin, alpha-1 [56582]
               1. Human (Homo sapiens) [56583] (3)
            2. Serpin K [56591]
               1. Tobacco hawkmoth (Manduca sexta) [56592] (1)
   2. beta-lactamase/transpeptidase-like [56600] (1)
      1. beta-lactamase/transpeptidase-like [56601] (1)
         1. beta-Lactamase/D-ala carboxypeptidase [56602] (8)
            1. D-ala carboxypeptidase/transpeptidase [56603]
               1. Streptomyces sp., K15 [56604] (1)
               2. Streptomyces sp., R61 [56605] (3)
            2. beta-Lactamase, class A [56606]
               1. Escherichia coli, TEM-1 [56607] (4)
               2. Escherichia coli, TOHO-1 [56608] (1)
               3. Staphylococcus aureus [56611] (10)
               4. Enterobacter cloacae, NMC-A carbapenemase [56613] (1)
               5. Streptomyces albus G [56614] (1)
            3. Penicillin-binding protein 2x (pbp-2x), transpeptidase domain [56624]
               1. Streptococcus pneumoniae [56625] (1)
   3. Heme-dependent catalase-like [56633] (1)
      1. Heme-dependent catalase-like [56634] (1)
         1. Heme-dependent catalases [56635] (1)
            1. Catalase I [56636]
               1. Proteus mirabilis [56640] (2)
   4. Carbohydrate phosphatase [56654] (1)
      1. Carbohydrate phosphatase [56655] (1)
         1. Inositol monophosphatase/fructose-1,6-bisphosphatase-like [56656] (2)
            1. Inositol monophosphatase [56663]
               1. Human (Homo sapiens) [56664] (1)
            2. Inositol polyphosphate 1-phosphatase [56667]
               1. Cow (Bos taurus), brain [56668] (1)
   5. DNA/RNA polymerases [56671] (1)
      1. DNA/RNA polymerases [56672] (3)
         1. DNA polymerase I [56673] (4)
            1. DNA polymerase I (Klenow fragment) [56674]
               1. Escherichia coli [56675] (2)
               2. Thermus aquaticus [56676] (3)
               3. Bacillus stearothermophilus, newly identified strain as yet unnamed [56677] (1)
            2. Family B DNA polymerase [56680]
               1. Bacteriophage RB69 [56681] (1)
         2. Reverse transcriptase [56686] (2)
            1. MMLV reverse transcriptase [56687]
               1. Moloney murine leukaemia virus, MoMLV [56688] (1)
            2. HIV-1 reverse transcriptase [56689]
               1. Human immunodeficiency virus type 1 [56690] (1)
         3. RNA-dependent RNA-polymerase [56694] (1)
            1. Viral RNA polymerase [56695]
               1. Poliovirus type 1, strain Mahoney [56696] (1)
   6. Prokaryotic type I DNA topoisomerase [56711] (1)
      1. Prokaryotic type I DNA topoisomerase [56712] (1)
         1. Prokaryotic type I DNA topoisomerase [56713] (1)
            1. DNA topoisomerase I, 67K N-terminal domain [56714]
               1. Escherichia coli [56715] (1)
   7. Type II DNA topoisomerase [56718] (1)
      1. Type II DNA topoisomerase [56719] (1)
         1. Type II DNA topoisomerase [56720] (2)
            1. DNA topoisomerase II, C-terminal fragment (residues 410-1202) [56721]
               1. Baker's yeast (Saccharomyces cerevisiae) [56722] (2)
            2. DNA Gyrase A [56723]
               1. Escherichia coli [56724] (1)
   8. Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment [56740] (1)
      1. Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment [56741] (1)
         1. Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment [56742] (1)
            1. Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment [56743]
               1. Baker's yeast (Saccharomyces cerevisiae) [56745] (1)
   9. Acetyl-CoA synthetase-like [56800] (1)
      1. Acetyl-CoA synthetase-like [56801] (1)
         1. Acetyl-CoA synthetase-like [56802] (1)
            1. Luciferase [56803]
               1. Firefly (Photinus pyralis) [56804] (2)
   10. Ribosomal protein L1 [56807] (1)
       1. Ribosomal protein L1 [56808] (1)
          1. Ribosomal protein L1 [56809] (1)
             1. Ribosomal protein L1 [56810]
                1. Thermus thermophilus [56811] (1)
6. Membrane and cell surface proteins and peptides [56835] (8)
   Does not include proteins in the immune system
   1. Toxins' membrane translocation domains [56836] (4)
      1. Colicin [56837] (1)
         1. Colicin [56838] (2)
            1. Colicin N [56841]
               1. Escherichia coli [56842] (1)
            2. Colicin Ia [56843]
               1. Escherichia coli [56844] (1)
      2. Diphtheria toxin, middle domain [56845] (1)
         1. Diphtheria toxin, middle domain [56846] (1)
            1. Diphtheria toxin, middle domain [56847]
               1. Corynebacterium diphtheriae [56848] (2)
      3. delta-Endotoxin (insectocide), N-terminal domain [56849] (1)
         1. delta-Endotoxin (insectocide), N-terminal domain [56850] (2)
            1. delta-Endotoxin (insectocide), N-terminal domain [56851]
               1. Bacillus thuringiensis tenebrionis, CRYIIIA (BT13) [56852] (1)
               2. Bacillus thuringiensis, CRYIA (A) [56853] (1)
      4. Bcl-2 inhibitors of programmed cell death [56854] (1)
         1. Bcl-2 inhibitors of programmed cell death [56855] (2)
            1. Apoptosis regulator Bcl-xL [56856]
               1. Human (Homo sapiens) [56857] (2)
               2. Rat (Rattus norvegicus) [56858] (1)
   2. Family A G protein-coupled receptor-like [81322] (1)
      1. Family A G protein-coupled receptor-like [81321] (1)
         1. Bacteriorhodopsin-like [81319] (3)
            1. Bacteriorhodopsin [56871]
               1. Archaeon Halobacterium halobium [56872] (3)
               2. Archaeon Halobacterium salinarum [56873] (4)
            2. Sensory rhodopsin II [64526]
               1. Archaeon Natronobacterium pharaonis [64527] (1)
   3. Transmembrane helix hairpin [81334] (1)
      1. F1F0 ATP synthase subunit C [81333] (1)
         1. F1F0 ATP synthase subunit C [81332] (1)
            1. F1F0 ATP synthase subunit C [56891]
               1. Escherichia coli [56892] (1)
   4. Transmembrane beta-barrels [56924] (1)
      1. Porins [56935] (2)
         1. Porin [56936] (3)
            1. Porin [56937]
               1. Escherichia coli, different sequences [56938] (9)
               2. Rhodobacter capsulatus [56939] (2)
               3. Rhodopseudomonas blastica, strain DSM2131 [56940] (8)
         2. Maltoporin-like [56942] (1)
            1. Maltoporin (also LamB protein) [56943]
               1. Escherichia coli [56944] (1)
   5. Leukocidin-like [56958] (1)
      1. Leukocidin-like [56959] (1)
         1. Leukocidin (pore-forming toxin) [56960] (1)
            1. Leucocidin K component LukF-PV [56963]
               1. Staphylococcus aureus [56964] (1)
   6. Perfringolysin [56977] (1)
      1. Perfringolysin [56978] (1)
         1. Perfringolysin [56979] (1)
            1. Perfringolysin [56980]
               1. Clostridium perfringens [56981] (1)
   7. Viral glycoprotein, central and dimerisation domains [56982] (1)
      1. Viral glycoprotein, central and dimerisation domains [56983] (1)
         1. Viral glycoprotein, central and dimerisation domains [56984] (1)
            1. Envelope glycoprotein [56985]
               1. Tick-borne encephalitis virus [56986] (1)
   8. Anthrax protective antigen [56987] (1)
      1. Anthrax protective antigen [56988] (1)
         1. Anthrax protective antigen [56989] (1)
            1. Anthrax protective antigen [56990]
               1. Anthrax bacillus (Bacillus anthracis) [56991] (1)
7. Small proteins [56992] (39)
   Usually dominated by metal ligand, heme, and/or disulfide bridges
   1. Insulin-like [56993] (1)
      1. Insulin-like [56994] (1)
         1. Insulin-like [56995] (2)
            1. Insulin [56996]
               1. Human (Homo sapiens) [56998] (1)
            2. Insulin-like growth factor [57002]
               1. Human (Homo sapiens) [57003] (4)
   2. Knottins (small inhibitors, toxins, lectins) [57015] (12)
      1. Plant lectins/antimicrobial peptides [57016] (2)
         1. Hevein-like agglutinin (lectin) domain [57017] (1)
            1. Hevein [57022]
               1. Hevea brasiliensis [57023] (1)
         2. Antimicrobial peptide 2, AC-AMP2 [57024] (1)
            1. Antimicrobial peptide 2, AC-AMP2 [57025]
               1. Tassel (Amaranthus caudatus) [57026] (1)
      2. Plant inhibitors of proteinases and amylases [57027] (1)
         1. Plant inhibitors of proteinases and amylases [57028] (2)
            1. Trypsin inhibitor [57029]
               1. Squash (Cucurbita maxima) [57031] (3)
               2. Jumping cucumber (Ecballium elaterium) [57033] (2)
      3. Cyclotides [57038] (2)
         1. Kalata B1 [57039] (1)
            1. Kalata B1 [57040]
               1. African plant (Oldenlandia affinis dc) [57041] (1)
         2. Circulin A [57045] (1)
            1. Circulin A [57046]
               1. Chassalia parviflora [57047] (1)
      4. Gurmarin-like [57048] (1)
         1. Gurmarin, a sweet taste-suppressing polypeptide [57049] (1)
            1. Gurmarin, a sweet taste-suppressing polypeptide [57050]
               1. Gymnema sylvestre [57051] (1)
      5. omega toxin-like [57059] (2)
         1. Conotoxin [57060] (6)
            1. Conotoxin [57061]
               1. Sea snail (Conus geographus), G IVa [57062] (2)
               2. Synthetic, based on Conus geographus, GS [57063] (1)
               3. Sea snail (Conus magus), M VIIc [57064] (1)
               4. Sea snail (Conus magus), M VIIa [57065] (2)
               5. Conus striatus, S VIb [57066] (1)
               6. Conus purpurascens, kappa-pVIIa [57068] (2)
         2. Spider toxins [57072] (4)
            1. omega-Agatoxin IV, IVa, IVb [57073]
               1. Funnel web spider (Agelenopsis aperta) [57074] (6)
            2. mu-Agatoxin-I [57075]
               1. Funnel web spider (Agelenopsis aperta) [57076] (1)
            3. Atracotoxin-hvI (versutoxin) [57077]
               1. Australian funnel-web spider (Hadronyche versuta) [57078] (2)
            4. Robustoxin [57081]
               1. Funnel-web spider (Atrax robustus) [57082] (1)
      6. Scorpion toxin-like [57095] (4)
         1. Long-chain scorpion toxins [57096] (10)
            1. Scorpion toxin [57097]
               1. Centruroides sculpturatus ewing, variant 3 [57098] (1)
               2. Centruroides sculpturatus ewing, variant 1 [57100] (2)
               3. Centruroides sculpturatus ewing, variant V [57101] (2)
               4. Scorpion (Androctonus australis hector), Toxin II [57102] (2)
               5. Mexican scorpion (Centruroides noxius hoffmann), toxin II [57103] (1)
               6. Scorpion (Buthotus judaicus), BJXTR-IT [57104] (1)
               7. Scorpion (Buthus martensii), toxin m8 [57105] (1)
            2. alpha toxin [57111]
               1. Leiurus quinquestriatus quinquestriatus, LQQIII [57112] (1)
               2. Scorpion (Leiurus quinquestriatus hebraeus) [57113] (2)
            3. LQH III alpha-like toxin, LQH [57114]
               1. Hebraei scorpion (Leiurus quinquestriatus hebraeus) [57115] (1)
         2. Short-chain scorpion toxins [57116] (18)
            1. Bmtx1 [57117]
               1. Buthus martensii [57118] (1)
            2. Bmktx [57119]
               1. Buthus martensii [57120] (1)
            3. Bmtx2 [57121]
               1. Buthus martensii [57122] (1)
            4. Margatoxin [57125]
               1. Scorpion (Centruroides margaritatus) [57126] (1)
            5. Noxiustoxin [57127]
               1. Scorpion (Centruroides noxius hoffmann) [57128] (1)
            6. Maurotoxin [57129]
               1. Scorpion (Scorpio maurus) [57130] (1)
            7. Charybdotoxin [57131]
               1. Scorpion (Leiurus quinquestriatus hebraeus) [57132] (3)
            8. Scyllatoxin [57133]
               1. Scorpion (Leiurus quinquestriatus hebraeus) [57134] (1)
            9. Agitoxin [57135]
               1. Scorpion (Leiurus quinquestriatus hebraeus) [57136] (1)
            10. Chlorootoxin [57137]
                1. Scorpion (Leiurus quinquestriatus), venom [57138] (1)
            11. Toxin ts kappa [57141]
                1. Scorpion (Tityus serrulatus) [57142] (1)
            12. Toxin I5a [57143]
                1. Scorpion (Buthus eupeus) [57144] (1)
            13. Toxin analog [57145]
                1. Scorpion (Androctonus mauretanicus mauretanicus) [57146] (1)
            14. Toxin analog P01 [57147]
                1. Scorpion (Androctonus mauretanicus mauretanicus) [57148] (1)
            15. OSK1 TOXIN [57149]
                1. Central asian scorpion (Orthochirus scrobiculosus) [57150] (1)
            16. Kaliotoxin (KTX) [57151]
                1. Scorpion (Androctonus mauretanicus mauretanicus) [57152] (2)
            17. LQ2 toxin [57153]
                1. Scorpion (Leiurus quinquestriatus hebraeus) [57154] (1)
            18. Pandinus toxin [57155]
                1. Emperor scorpion (Pandinus imperator), PITX-Ka [57156] (1)
         3. Insect defensins [57163] (2)
            1. Drosomycin [57164]
               1. Fruit fly (Drosophila melanogaster) [57165] (1)
            2. Defensin A [57166]
               1. Flesh fly (Phormia terranovae) [57167] (1)
         4. Plant defensins [57170] (5)
            1. gamma-Thionin [57171]
               1. Barley (Hordeum vulgare) [57172] (1)
               2. Wheat (Triticum turgidum) [57173] (1)
            2. Antifungal protein 1 (RS-AFP1) [57174]
               1. Radish (Raphanus sativus) [57175] (1)
            3. Antimicrobial protein 1 (AH-AMP1) [57176]
               1. Horse chestnut (Aesculus hippocastanum) [57177] (1)
            4. Brazzein [57178]
               1. J'oublie (Pentadiplandra brazzeana) [57179] (2)
      7. Cellulose-binding domain [57180] (1)
         1. Cellulose-binding domain [57181] (1)
            1. Cellobiohydrolase I [57182]
               1. Trichoderma reesei, ct-cbh I [57183] (6)
      8. Colipase-like [57190] (1)
         1. Colipase-like [57191] (2)
            1. (Pro)colipase [57192]
               1. Pig (Sus scrofa) [57193] (4)
            2. Intestinal toxin 1 [57194]
               1. Black mamba (Dendroaspis polylepis polylepis) [57195] (2)
      9. EGF/Laminin [57196] (2)
         1. EGF-type module [57197] (14)
            1. Factor IX (IXa) [57198]
               1. Human (Homo sapiens) [57199] (1)
            2. Coagulation factor VIIa [57201]
               1. Human (Homo sapiens) [57202] (1)
            3. E-selectin, EGF-domain [57203]
               1. Human (Homo sapiens) [57204] (1)
            4. Factor X, N-terminal module [57205]
               1. Cow (Bos taurus) [57207] (4)
            5. Prostaglandin H2 synthase-1, EGF-like module [57210]
               1. Sheep (Ovis aries) [57211] (1)
            6. P-selectin, EGF-domain [57213]
               1. Human (Homo sapiens) [57214] (1)
            7. Epidermal growth factor, EGF [57215]
               1. Mouse (Mus musculus) [57216] (7)
            8. Transforming growth factor alpha [57217]
               1. Human (Homo sapiens) [57218] (5)
            9. Plasminogen activator (urokinase-type) [57221]
               1. Human (Homo sapiens) [57222] (1)
            10. Heregulin-alpha, EGF-like domain [57223]
                1. Human (Homo sapiens) [57224] (4)
            11. Thrombomodulin, different EGF-like domains [57225]
                1. Human (Homo sapiens) [57226] (4)
            12. Fibrillin-1 [57227]
                1. Human (Homo sapiens) [57228] (4)
            13. Complement protease C1R [57229]
                1. Human (Homo sapiens) [57230] (1)
            14. Plasminogen activator (tissue-type), t-PA [57231]
                1. Human (Homo sapiens) [57232] (1)
         2. Laminin-type module [57233] (1)
            1. Laminin gamma1 chain [57234]
               1. Mouse (Mus musculus) [57235] (4)
      10. Bowman-Birk inhibitor, BBI [57247] (1)
          1. Bowman-Birk inhibitor, BBI [57248] (2)
             1. Bowman-Birk inhibitor, BBI [57249]
                1. Soybean (Glycine max), PI-II [57250] (1)
                2. Soybean (Glycine max) [57251] (2)
      11. Elafin-like [57256] (1)
          1. Elafin-like [57257] (1)
             1. Elafin, elastase-specific inhibitor [57258]
                1. Human (Homo sapiens) [57259] (1)
      12. Leech antihemostatic proteins [57262] (2)
          1. Huristasin-like [57263] (2)
             1. Hirustasin [57264]
                1. Medicinal leech (Hirudo medicinalis) [57265] (2)
             2. Factor Xa inhibitor antistasin [57268]
                1. Mexican leech (Haementeria officinalis) [57269] (2)
          2. Hirudin-like [57270] (2)
             1. Hirudin [57271]
                1. Leech (Hirudo medicinalis) [57272] (5)
             2. Decorsin [57273]
                1. North american leech (Macrobdella decora) [57274] (1)
   3. PMP inhibitors [57282] (1)
      1. PMP inhibitors [57283] (1)
         1. PMP inhibitors [57284] (1)
            1. Protease inhibitor PMP-C [57285]
               1. Migratory locust (Locusta migratoria) [57286] (1)
   4. Amb V allergen [57295] (1)
      1. Amb V allergen [57296] (1)
         1. Amb V allergen [57297] (1)
            1. Amb V allergen [57298]
               1. Giant ragweed (Ambrosia trifida), pollen [57299] (3)
   5. Snake toxin-like [57301] (1)
      1. Snake toxin-like [57302] (3)
         1. Snake venom toxins [57303] (19)
            1. Erabutoxin B (also neurotoxin B) [57304]
               1. Sea snake (Laticauda semifasciata) [57305] (5)
            2. gamma-Cardiotoxin [57306]
               1. Snake (Naja nigricollis) [57307] (2)
            3. Fasciculin [57308]
               1. Green mamba (Dendroaspis angusticeps) [57309] (2)
            4. Erabutoxin A [57310]
               1. Broad-banded blue sea snake (Laticauda semifasciata) [57311] (2)
            5. Neurotoxin I [57312]
               1. Snake (Naja naja oxiana) [57313] (1)
            6. Cardiotoxin V [57316]
               1. Taiwan cobra (Naja naja atra) [57317] (1)
            7. alpha-Cobratoxin [57318]
               1. Cobra (Naja naja siamensis) [57319] (2)
            8. Long neurotoxin 1 (component LSIII) [57320]
               1. Sea snake (Laticauda semifasciata) [57321] (1)
            9. FS2 toxin [57322]
               1. Black mamba (Dendroaspis polylepis polylepis) [57323] (1)
            10. Cardiotoxin CTXI [57330]
                1. Taiwan cobra (Naja naja atra) [57331] (1)
            11. Cardiotoxin CTX IIB [57332]
                1. Naja mossambica mossambica [57333] (1)
            12. Cardiotoxin II [57334]
                1. Taiwan cobra (Naja naja atra) [57335] (2)
            13. Cardiotoxin III [57337]
                1. Taiwan cobra (Naja naja atra) [57338] (2)
            14. Cardiotoxin IV [57339]
                1. Taiwan cobra (Naja naja atra) [57340] (2)
            15. Cobrotoxin II (ct2) [57341]
                1. Taiwan cobra (Naja naja atra) [57342] (2)
            16. alpha-Toxin [57344]
                1. Spitting cobra (Naja nigricollis) [57345] (1)
                2. Black mamba (Dendroaspis polylepis polylepis) [57346] (1)
            17. Neurotoxin II (Nt2, cobrotoxin B) [57347]
                1. Central asian cobra (Naja naja oxiana) [57348] (1)
            18. Toxin B (long neurotoxin) [57349]
                1. King cobra (Ophiophagus hannah) [57350] (2)
         2. Dendroaspin [57351] (1)
            1. Dendroaspin [57352]
               1. Dendroaspis jamesoni kaimosae [57353] (1)
         3. Extracellular domain of cell surface receptors [57354] (1)
            1. CD59 [57355]
               1. Human (Homo sapiens) [57356] (5)
   6. BPTI-like [57361] (1)
      1. BPTI-like [57362] (2)
         1. Small Kunitz-type inhibitors & BPTI-like toxins [57363] (9)
            1. Pancreatic trypsin inhibitor, BPTI [57364]
               1. Cow (Bos taurus) [57365] (12)
            2. Collagen type VI (domain C5 from alpha 3 chain) [57366]
               1. Human (Homo sapiens) [57367] (3)
            3. Tissue factor pathway inhibitor [57368]
               1. Human (Homo sapiens) [57369] (1)
            4. Bikunin from inter-alpha-inhibitor complex [57372]
               1. Human (Homo sapiens) [57373] (2)
            5. alpha-Dendrotoxin [57374]
               1. Green mamba (Dendroaspis angusticeps) [57375] (1)
            6. Trypsin inhibitor [57378]
               1. Sea anemone (Stichodactyla helianthus) [57379] (1)
            7. Dendrotoxin K [57380]
               1. Black mamba (Dendroaspis polylepis polylepis) [57381] (1)
            8. Dendrotoxin I [57382]
               1. African elapid snake (Dendroaspis polylepis polylepis) [57383] (2)
            9. Calcicludine (cac) [57384]
               1. Green mamba (Dendroaspis angusticeps) [57385] (1)
         2. Soft tick anticoagulant proteins [57386] (1)
            1. Anticoagulant protein, factor Xa inhibitor [57389]
               1. Soft tick (Ornithodoros moubata) [57390] (2)
   7. Defensin-like [57391] (1)
      1. Defensin-like [57392] (1)
         1. Defensin [57393] (6)
            1. Beta-defensin, BD [63384]
               1. Cow (Bos taurus), BD12 [63386] (1)
            2. BDs-I defensin [57403]
               1. Sea anemone (Anemonia sulcata) [57404] (2)
            3. Sea anemone neurotoxin-1 [57405]
               1. Sea anemone (Stichodactyla helianthus) [57406] (3)
            4. Sea anemone toxin IA [57407]
               1. Sea anemone (Anemonia sulcata) [57408] (1)
            5. Anthopleurin-A [57409]
               1. Giant green sea anemone (Anthopleura xanthogrammica) [57410] (1)
            6. Anthopleurin-B [57411]
               1. Giant green sea anemone (Anthopleura xanthogrammica) [57412] (1)
   8. Hairpin loop containing domain-like [57413] (1)
      1. Hairpin loop containing domain-like [57414] (1)
         1. Hairpin loop containing domain [57415] (1)
            1. Hepatocyte growth factor [57416]
               1. Human (Homo sapiens) [57417] (1)
   9. Neurotoxin III (ATX III) [57418] (1)
      1. Neurotoxin III (ATX III) [57419] (1)
         1. Neurotoxin III (ATX III) [57420] (1)
            1. Neurotoxin III (ATX III) [57421]
               1. Sea anemone (Anemonia sulcata) [57422] (1)
   10. LDL receptor-like module [57423] (1)
       1. LDL receptor-like module [57424] (1)
          1. LDL receptor-like module [57425] (1)
             1. Ligand-binding domain of low-density lipoprotein receptor [57426]
                1. Human (Homo sapiens) [57427] (3)
   11. Crambin-like [57428] (1)
       1. Crambin-like [57429] (1)
          1. Crambin-like [57430] (3)
             1. Crambin [57431]
                1. Abyssinian cabbage (Crambe abyssinica) [57432] (6)
             2. beta-Purothionin [57433]
                1. Wheat (Triticum aestivum) [57434] (1)
             3. alpha-1-Purothionin [57435]
                1. Wheat (Triticum aestivum) [57436] (1)
   12. Kringle-like [57439] (1)
       1. Kringle-like [57440] (2)
          1. Kringle modules [57441] (4)
             1. Plasminogen [63400]
                1. Human (Homo sapiens) [63401] (7)
             2. Prothrombin [57448]
                1. Cow (Bos taurus) [57449] (3)
             3. Urokinase-type plasminogen activator [57453]
                1. Human (Homo sapiens) [57454] (2)
             4. Apolipoprotein A [57455]
                1. Human (Homo sapiens), IV-10/M66 variant [57456] (3)
          2. Fibronectin type II module [57459] (2)
             1. PDC-109, collagen-binding type II domain [57460]
                1. Cow (Bos taurus) [57461] (1)
             2. Fibronectin [57462]
                1. Human (Homo sapiens) [57463] (1)
   13. Kazal-type serine protease inhibitors [100894] (1)
       1. Kazal-type serine protease inhibitors [100895] (1)
          1. Ovomucoid domain III-like [57468] (6)
             1. Ovomucoid domains [57469]
                1. Turkey (Meleagris gallopavo) [57470] (4)
                2. Japanese quail (Coturnix coturnix japonica) [57471] (1)
                3. Silver pheasant (Lophura nycthemera) [57472] (2)
             2. Secretory trypsin inhibitor [57473]
                1. Human (Homo sapiens) [57474] (1)
             3. Seminal plasma inhibitor IIa [57480]
                1. Cow (Bos taurus) [57481] (2)
             4. PEC-60 peptide [57482]
                1. Pig (Sus scrofa) [57483] (1)
   14. Plant proteinase inhibitors [100896] (1)
       1. Plant proteinase inhibitors [100897] (1)
          1. Plant proteinase inhibitors [57486] (1)
             1. Multidomain proteinase inhibitor [57489]
                1. Winged tobacco (Nicotiana alata) [57490] (1)
   15. Trefoil/Plexin domain-like [57491] (1)
       1. Trefoil [57492] (1)
          1. Trefoil [57493] (2)
             1. Pancreatic spasmolytic polypeptide [57494]
                1. Pig (Sus scrofa) [57495] (2)
             2. PNR-2/PS2, TFF1 [57496]
                1. Human (Homo sapiens) [57497] (1)
   16. Cystine-knot cytokines [57500] (1)
       1. Cystine-knot cytokines [57501] (2)
          1. Transforming growth factor (TGF)-beta [57507] (3)
             1. TGF-beta3 [57508]
                1. Human (Homo sapiens) [57509] (2)
             2. TGF-beta2 [57510]
                1. Human (Homo sapiens) [57511] (2)
             3. Bone morphogenetic protein-7 (BMP-7) [57514]
                1. Human (Homo sapiens) [57515] (1)
          2. Neurotrophin [57520] (1)
             1. beta-Nerve growth factor [57525]
                1. Mouse (Mus musculus) [57526] (1)
   17. Complement control module/SCR domain [57534] (1)
       1. Complement control module/SCR domain [57535] (1)
          1. Complement control module/SCR domain [57536] (2)
             1. Factor H, 15th and 16th modules [57537]
                1. Human (Homo sapiens) [57538] (4)
             2. Complement control protein [57539]
                1. Vaccinia virus [57540] (6)
   18. Crisp domain-like [57545] (1)
       1. Crisp domain-like [57546] (1)
          1. Sea anemone toxin k [57547] (2)
             1. Sea anemone toxin k [57548]
                1. Sea anemone (Bunodosoma granulifera), BGK [57549] (1)
                2. Sun anemone (Stichodactyla helianthus), SHK [57550] (2)
   19. Blood coagulation inhibitor (disintegrin) [57551] (1)
       1. Blood coagulation inhibitor (disintegrin) [57552] (1)
          1. Blood coagulation inhibitor (disintegrin) [57553] (2)
             1. Echistatin [57554]
                1. Saw-scaled viper Echis carinatus [57555] (1)
             2. Flavoridin (triflavin) [57556]
                1. Habu snake (Trimeresurus flavoviridis) [57557] (1)
   20. Serine protease inhibitors [57566] (1)
       1. Serine protease inhibitors [57567] (1)
          1. ATI-like [57568] (1)
             1. Ascaris trypsin inhibitor, ATI [57569]
                1. Pig roundworm (Ascaris Lumbricoides), variant suum [57570] (4)
   21. TB module/8-cys domain [57580] (1)
       1. TB module/8-cys domain [57581] (1)
          1. TB module/8-cys domain [57582] (1)
             1. Fibrillin [57583]
                1. Human (Homo sapiens) [57584] (1)
   22. Heparin-binding domain from vascular endothelial growth factor [57592] (1)
       1. Heparin-binding domain from vascular endothelial growth factor [57593] (1)
          1. Heparin-binding domain from vascular endothelial growth factor [57594] (1)
             1. Heparin-binding domain from vascular endothelial growth factor [57595]
                1. Human (Homo sapiens) [57596] (2)
   23. Antifungal protein (AGAFP) [57597] (1)
       1. Antifungal protein (AGAFP) [57598] (1)
          1. Antifungal protein (AGAFP) [57599] (1)
             1. Antifungal protein (AGAFP) [57600]
                1. Mold (Aspergillus giganteus) [57601] (1)
   24. FnI-like domain [57602] (1)
       1. FnI-like domain [57603] (1)
          1. Fibronectin type I module [57604] (2)
             1. Fibronectin [57605]
                1. Human (Homo sapiens) [57606] (2)
             2. Tissue-type plasminogen activator, t-PA [57607]
                1. Human (Homo sapiens) [57608] (3)
   25. GLA-domain [57629] (1)
       1. GLA-domain [57630] (1)
          1. GLA-domain [57631] (3)
             1. Prothrombin [57634]
                1. Cow (Bos taurus) [57635] (3)
             2. Coagulation factor IX (IXa) [57636]
                1. Human (Homo sapiens) [57637] (3)
             3. Coagulation factor X [57639]
                1. Cow (Bos taurus) [57640] (2)
   26. HIV-1 VPU cytoplasmic domain [57646] (1)
       1. HIV-1 VPU cytoplasmic domain [57647] (1)
          1. HIV-1 VPU cytoplasmic domain [57648] (1)
             1. HIV-1 VPU cytoplasmic domain [57649]
                1. Human immunodeficiency virus type 1 [57650] (1)
   27. HIPIP (high potential iron protein) [57651] (1)
       1. HIPIP (high potential iron protein) [57652] (1)
          1. HIPIP (high potential iron protein) [57653] (3)
             1. HIPIP (high potential iron protein) [57654]
                1. Allochromatium vinosum, (formerly Chromatium vinosum) [57656] (5)
                2. Ectothiorhodospira halophila [57658] (2)
                3. Ectothiorhodospira vacuolata [57659] (1)
   28. C2H2 and C2HC zinc fingers [57666] (1)
       1. C2H2 and C2HC zinc fingers [57667] (1)
          1. Classic zinc finger, C2H2 [57668] (8)
             1. V(D)J recombination activating protein 1 (RAG1), dimerization domain [57671]
                1. Mouse (Mus musculus) [57672] (1)
             2. ADR1 [57675]
                1. Synthetic, based on Saccharomyces cerevisiae sequence [57676] (6)
             3. XFIN, third domain [57677]
                1. Xenopus laevis [57678] (1)
             4. ZFY [57679]
                1. Human (Homo sapiens) [57680] (2)
             5. SWI5 zinc-finger domains [57681]
                1. Baker's yeast (Saccharomyces cerevisiae) [57682] (2)
             6. Enhancer binding protein [57685]
                1. Human (Homo sapiens) [57686] (4)
             7. Transcription factor sp1 [57687]
                1. Human (Homo sapiens) [57688] (2)
             8. Transactivation domain of cre-bp1/atf-2 [57689]
                1. Human (Homo sapiens) [57690] (1)
   29. Zn2/Cys6 DNA-binding domain [57700] (1)
       1. Zn2/Cys6 DNA-binding domain [57701] (1)
          1. Zn2/Cys6 DNA-binding domain [57702] (3)
             1. Gal4 [57703]
                1. Baker's yeast (Saccharomyces cerevisiae) [57704] (1)
             2. Hap1 (Cyp1) [57709]
                1. Baker's yeast (Saccharomyces cerevisiae) [57710] (1)
             3. CD2-Lac9 [57711]
                1. Milk yeast (Kluyveromyces lactis) [57712] (1)
   30. Glucocorticoid receptor-like (DNA-binding domain) [57715] (1)
       1. Glucocorticoid receptor-like (DNA-binding domain) [57716] (5)
          1. Erythroid transcription factor GATA-1 [57717] (1)
             1. Erythroid transcription factor GATA-1 [57718]
                1. Mouse (Mus musculus) [57720] (1)
          2. Nuclear receptor [57721] (4)
             1. Retinoid X receptor (RXR-alpha) DNA-binding domain [57722]
                1. Human (Homo sapiens) [57723] (1)
             2. Estrogen receptor DNA-binding domain [57728]
                1. Human and chicken (Homo sapiens) and (Gallus gallus) [57729] (1)
             3. Glucocorticoid receptor DNA-binding domain [57730]
                1. Rat (Rattus norvegicus) [57731] (3)
             4. Retinoic acid receptor DNA-binding domain [57732]
                1. Human (Homo sapiens) [57733] (1)
          3. LIM domain [57736] (3)
             1. Cysteine-rich (intestinal) protein, CRP, CRIP [57737]
                1. Chicken (Gallus gallus) [57738] (2)
                2. Japanese quail (Coturnix coturnix japonica), CRP2 [57739] (4)
                3. Rat (Rattus rattus) [57740] (2)
          4. LASP-1 [57743] (1)
             1. LASP-1 [57744]
                1. Pig (Sus scrofa) [57745] (1)
          5. DNA repair factor XPA DNA- and RPA-binding domain, N-terminal subdomain [57746] (1)
             1. DNA repair factor XPA DNA- and RPA-binding domain, N-terminal subdomain [57747]
                1. Human (Homo sapiens) [57748] (1)
   31. Retrovirus zinc finger-like domains [57755] (1)
       1. Retrovirus zinc finger-like domains [57756] (1)
          1. Retrovirus zinc finger-like domains [57757] (3)
             1. GAG protein p55 [57758]
                1. Human immunodeficiency virus-based, synthetic [57759] (1)
             2. HIV nucleocapsid [57760]
                1. Human immunodeficiency virus type 1, different isolates [57761] (2)
                2. Human immunodeficiency virus type 2 [57762] (1)
   32. Rubredoxin-like [57769] (5)
       1. Methionyl-tRNA synthetase (MetRS), Zn-domain [57770] (1)
          1. Methionyl-tRNA synthetase (MetRS), Zn-domain [57771] (1)
             1. Methionyl-tRNA synthetase (MetRS), Zn-domain [57772]
                1. Escherichia coli [57773] (2)
       2. Microbial and mitochondrial ADK, insert "zinc finger" domain [57774] (1)
          1. Microbial and mitochondrial ADK, insert "zinc finger" domain [57775] (3)
             1. Microbial and mitochondrial ADK, insert "zinc finger" domain [57776]
                1. Bacillus stearothermophilus [57777] (3)
                2. Cow (Bos taurus), mitochondrial izozyme-2 [57780] (2)
                3. Baker's yeast (Saccharomyces cerevisiae) [57781] (3)
       3. Zinc beta-ribbon [57783] (2)
          1. Transcriptional factor domain [57784] (3)
             1. Transcriptional factor SII, C-terminal domain [57785]
                1. Human (Homo sapiens) [57786] (1)
             2. Transcription initiation factor TFIIB, N-terminal domain [57789]
                1. Archaeon Pyrococcus furiosus [57790] (1)
             3. RBP9 subunit of RNA polymerase II [57787]
                1. Archaeon Thermococcus celer [57788] (1)
          2. Prokaryotic DNA topoisomerase I, a C-terminal fragment [57795] (1)
             1. Prokaryotic DNA topoisomerase I, a C-terminal fragment [57796]
                1. Escherichia coli [57797] (2)
       4. Rubredoxin-like [57802] (2)
          1. Rubredoxin [57803] (6)
             1. Rubredoxin [57804]
                1. Desulfovibrio vulgaris [57805] (3)
                2. Desulfovibrio gigas [57806] (1)
                3. Desulfovibrio desulfuricans, strain 27774 [57807] (1)
                4. Clostridium pasteurianum [57808] (6)
                5. Archaeon Pyrococcus furiosus [57809] (3)
             2. Rubrerythrin, C-terminal domain [57811]
                1. Desulfovibrio vulgaris [57812] (1)
          2. Desulforedoxin [57813] (1)
             1. Desulfoferrodoxin N-terminal domain [57816]
                1. Desulfovibrio desulfuricans [57817] (1)
       5. NZF domain [90213] (1)
          1. NZF domain [90214] (1)
             1. Npl4 [90215]
                1. Rat (Rattus norvegicus) [90216] (2)
   33. B-box zinc-binding domain [57844] (1)
       1. B-box zinc-binding domain [57845] (1)
          1. B-box zinc-binding domain [57846] (1)
             1. Nuclear factor XNF7 [57847]
                1. African clawed frog (Xenopus laevis) [57848] (1)
   34. RING/U-box [57849] (1)
       1. RING/U-box [57850] (1)
          1. RING finger domain, C3HC4 [57851] (3)
             1. V(D)J recombination activating protein 1 (RAG1), dimerization domain [57854]
                1. Mouse (Mus musculus) [57855] (1)
             2. Immediate early protein, IEEHV [57856]
                1. Equine herpes virus type 1 [57857] (1)
             3. Acute promyelocytic leukaemia proto-oncoprotein PML [57858]
                1. Human (Homo sapiens) [57859] (1)
   35. Metallothionein [57867] (1)
       1. Metallothionein [57868] (1)
          1. Metallothionein [57869] (5)
             1. Metallothionein [57870]
                1. Human (Homo sapiens) [57871] (2)
                2. Rabbit (Oryctolagus cuniculus) [57872] (2)
                3. Rat (Rattus rattus) [57873] (3)
                4. Crab (Callinectes sapidus), alpha and beta domains [57875] (4)
                5. Baker's yeast (Saccharomyces cerevisiae) [57876] (4)
   36. Ada DNA repair protein, N-terminal domain (N-Ada 10) [57883] (1)
       1. Ada DNA repair protein, N-terminal domain (N-Ada 10) [57884] (1)
          1. Ada DNA repair protein, N-terminal domain (N-Ada 10) [57885] (1)
             1. Ada DNA repair protein, N-terminal domain (N-Ada 10) [57886]
                1. Escherichia coli [57887] (1)
   37. Cysteine-rich domain [57888] (1)
       1. Cysteine-rich domain [57889] (1)
          1. Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) [57890] (3)
             1. Protein kinase C-delta (PKCdelta) [57891]
                1. Mouse (Mus musculus) [57892] (2)
             2. RAF-1 [57893]
                1. Human (Homo sapiens) [57894] (2)
             3. Protein kinase c-gamma [57895]
                1. Rat (Rattus rattus) [57896] (2)
   38. Toxic hairpin [57006] (2)
       1. Heat-stable enterotoxin B [57007] (1)
          1. Heat-stable enterotoxin B [57008] (1)
             1. Heat-stable enterotoxin B [57009]
                1. Escherichia coli [57010] (1)
       2. Neurotoxin B-IV [57011] (1)
          1. Neurotoxin B-IV [57012] (1)
             1. Neurotoxin B-IV [57013]
                1. Milky ribbon worm (Cerebratulus lacteus) [57014] (1)
   39. Zn-binding domains of ADDBP [57916] (1)
       1. Zn-binding domains of ADDBP [57917] (1)
          1. Zn-binding domains of ADDBP [57918] (2)
             1. First Zn-domain of early E2A DNA-binding protein, ADDBP [57919]
                1. Human adenovirus type 5 [57920] (2)
             2. Second Zn-domain of early E2A DNA-binding protein, ADDBP [57921]
                1. Human adenovirus type 5 [57922] (2)
8. Coiled coil proteins [57942] (3)
   Not a true class
   1. Parallel coiled-coil [57943] (4)
      1. Triple coiled coil domain of C-type lectins [57944] (1)
         1. Triple coiled coil domain of C-type lectins [57945] (2)
            1. Mannose-binding protein A [57946]
               1. Human (Homo sapiens) [57948] (1)
            2. Tetranectin [57951]
               1. Human (Homo sapiens) [57952] (1)
      2. Leucine zipper domain [57959] (1)
         1. Leucine zipper domain [57960] (1)
            1. GCN4 [57961]
               1. Baker's yeast (Saccharomyces cerevisiae) [57962] (1)
      3. Inovirus (filamentous phage) major coat protein [57987] (1)
         1. Inovirus (filamentous phage) major coat protein [57988] (7)
            1. Inovirus (filamentous phage) major coat protein [57989]
               1. Bacteriophage fd [57990] (4)
               2. Bacteriophage pf1 [57991] (6)
               3. Bacteriophage if1 [57992] (1)
               4. Bacteriophage ike [57993] (1)
               5. Bacteriophage xf [57994] (1)
               6. Bacteriophage M13 [57995] (2)
               7. Bacteriophage pf3 [57996] (1)
      4. Fibritin [58046] (1)
         1. Fibritin [58047] (1)
            1. Fibritin [58048]
               1. Bacteriophage T4 [58049] (1)
   2. Stalk segment of viral fusion proteins [58063] (1)
      1. Virus ectodomain [58069] (1)
         1. Virus ectodomain [58070] (2)
            1. Retrovius gp41 protease-resistant core [58071]
               1. Human immunodeficiency virus type 1 [58072] (1)
            2. MoMLV p15 core fragment [58627]
               1. Molomey murine leukaemia virus, MoMLV [58628] (1)
   3. Antiparallel coiled-coil [58086] (1)
      1. Colicin Ia, N-terminal domain [58096] (1)
         1. Colicin Ia, N-terminal domain [58097] (1)
            1. Colicin Ia, N-terminal domain [58098]
               1. Escherichia coli [58099] (1)
9. Low resolution protein structures [58117] (1)
   Not a true class
   1. Proteins of incorrect, partial and unknown sequence [58207] (1)
      1. Proteins of incorrect, partial and unknown sequence [58208] (1)
         1. Proteins of incorrect, partial and unknown sequence [58209] (2)
            1. Hexokinase [58224]
               1. Baker's yeast (Saccharomyces cerevisiae), BIII [58225] (1)
               2. Baker's yeast (Saccharomyces cerevisiae), A [58226] (1)
10. Peptides [58231] (44)
    Peptides and fragments. Not a true class
    1. Lantibiotic peptides [58243] (1)
       1. Lantibiotic peptides [58244] (1)
          1. Actagardine [58245] (1)
             1. Actagardine [58246]
                1. Actinoplanes liguriae/Actinoplanes garbadinensis [58247] (1)
    2. Leucocin-like bacteriocin [100898] (1)
       1. Leucocin-like bacteriocin [100899] (1)
          1. Leucocin-like bacteriocin [100900] (1)
             1. Leucocin [58254]
                1. Leuconostoc gelidum [58255] (2)
    3. Antimicrobial beta-hairpin [58251] (1)
       1. Antimicrobial beta-hairpin [58252] (2)
          1. theta defensin-like [58262] (1)
             1. Protegrin 1 (PG1) [58263]
                1. Pig (Sus scrofa) [58264] (1)
          2. Lactoferricin B (lfcinb) [58265] (1)
             1. Lactoferricin B (lfcinb) [58266]
                1. Synthetic, based on Bos taurus sequence [58267] (1)
    4. Antimicrobial helix [58268] (1)
       1. Antimicrobial helix [58269] (1)
          1. Magainin [58270] (1)
             1. Magainin 2 [58271]
                1. Xenopus laevis [58272] (1)
    5. Peptide hormones [58283] (1)
       1. Peptide hormones [58284] (1)
          1. Peptide hormones [58285] (7)
             1. Pancreatic polypeptide [58286]
                1. Cow (Bos taurus) [58287] (1)
                2. Turkey (Meleagris gallopavo) [58288] (1)
             2. Neuropeptide Y [58289]
                1. Human (Homo sapiens) [58290] (1)
             3. Deaminooxytocin [58296]
                1. Syntehtic [58297] (1)
             4. Glucagon [58298]
                1. Pig (Sus scrofa) [58299] (1)
                2. Synthetic, Homo sapiens analog [58300] (1)
             5. Calcitonin [58301]
                1. Eel (Anguilla japonica) [58302] (1)
    6. delta toxin-like [58307] (1)
       1. delta-Toxin [58308] (1)
          1. delta-Toxin [58309] (1)
             1. delta-Toxin [58310]
                1. Synthetic [58311] (2)
    7. Arg-rich RNA binding peptides [58321] (1)
       1. HIV-1 REV fragments [58326] (1)
          1. HIV-1 REV fragments [58327] (1)
             1. HIV-1 REV fragments [58328]
                1. Human immunodeficiency virus type 1 [58329] (1)
    8. VPR protein fragments [58353] (1)
       1. VPR protein fragments [58354] (1)
          1. VPR protein fragments [58355] (1)
             1. VPR protein fragments [58356]
                1. Human immunodeficiency virus type 1 [58357] (4)
    9. Inactivation gate of potassium and sodium channels [58358] (1)
       1. Inactivation gate of potassium and sodium channels [58359] (1)
          1. Inactivation gate of potassium and sodium channels [58360] (3)
             1. Potassium channel RAW3 [58361]
                1. Synthetic, based on mammalian sequence [58362] (1)
                2. Synthetic, expressed in Escherichia coli [58363] (2)
             2. Potassium channel RCK4 [58364]
                1. Synthetic, based on mammalian sequence [58365] (1)
    10. Coagulation factor VIII, membrane-binding peptide [58368] (1)
        1. Coagulation factor VIII, membrane-binding peptide [58369] (1)
           1. Coagulation factor VIII, membrane-binding peptide [58370] (1)
              1. Coagulation factor VIII, membrane-binding peptide [58371]
                 1. Human (Homo sapiens) [58372] (2)
    11. Phosphocholine cytidylyltransferase membrane-binding peptides [58373] (1)
        1. Phosphocholine cytidylyltransferase membrane-binding peptides [58374] (1)
           1. Phosphocholine cytidylyltransferase membrane-binding peptides [58375] (1)
              1. Phosphocholine cytidylyltransferase membrane-binding peptides [58376]
                 1. Rat (Rattus norvegicus) [58377] (2)
    12. Parathyroid hormone fragments (residues between 1 and 39) [58378] (1)
        1. Parathyroid hormone fragments (residues between 1 and 39) [58379] (1)
           1. Parathyroid hormone fragments (residues between 1 and 39) [58380] (2)
              1. Parathyroid hormone fragments (residues between 1 and 39) [58381]
                 1. Human (Homo sapiens) [58382] (12)
                 2. Cow (Bos taurus) [58383] (1)
    13. Liposaccharide-binding protein CAP18 (residues 106-137) [58389] (1)
        1. Liposaccharide-binding protein CAP18 (residues 106-137) [58390] (1)
           1. Liposaccharide-binding protein CAP18 (residues 106-137) [58391] (1)
              1. Liposaccharide-binding protein CAP18 (residues 106-137) [58392]
                 1. Synthetic, based on rabbit sequence [58393] (1)
    14. Polymorphic antigen SPAM-H1 (residues 90-127) [58394] (1)
        1. Polymorphic antigen SPAM-H1 (residues 90-127) [58395] (1)
           1. Polymorphic antigen SPAM-H1 (residues 90-127) [58396] (1)
              1. Polymorphic antigen SPAM-H1 (residues 90-127) [58397]
                 1. Malaria parasite (Plasmodium falciparum) [58398] (1)
    15. Insect toxins [58399] (1)
        1. Insect toxins [58400] (1)
           1. Mellitin-like toxins [58401] (1)
              1. Mellitin [58402]
                 1. Honeybee (Apis mellifera) [58403] (1)
    16. Tertiapin [58404] (1)
        1. Tertiapin [58405] (1)
           1. Tertiapin [58406] (1)
              1. Tertiapin [58407]
                 1. Honeybee venom (Apis mellifera) [58408] (1)
    17. Pilin fragments [58420] (1)
        1. Pilin fragments [58421] (1)
           1. Pilin fragments [58422] (3)
              1. Pilin, fragment 128-144 [58423]
                 1. Pseudomonas aeruginosa, strain k pak pilin [58424] (4)
                 2. Pseudomonas aeruginosa, strain o pao pilin [58425] (2)
                 3. Pseudomonas aeruginosa, strain kb7 [58426] (2)
    18. RP71935 [58427] (1)
        1. RP71935 [58428] (1)
           1. RP71935 [58429] (1)
              1. RP71935 [58430]
                 1. Actinomycete, strain sp9440 [58431] (2)
    19. Atrial natriuretic peptide [58432] (1)
        1. Atrial natriuretic peptide [58433] (1)
           1. Atrial natriuretic peptide [58434] (1)
              1. Atrial natriuretic peptide [58435]
                 1. Human (Homo sapiens) [58436] (1)
    20. Compstatin [58437] (1)
        1. Compstatin [58438] (1)
           1. Compstatin [58439] (1)
              1. Compstatin [58440]
                 1. Synthetic chemical synthesis [58441] (1)
    21. Endothelin-like [58449] (1)
        1. Endothelin-like [58450] (1)
           1. Endothelin-like [58451] (2)
              1. Endothelin-1 [58452]
                 1. Human (Homo sapiens) [58453] (2)
              2. Sarafotoxin S6B [58455]
                 1. Synthetic, based on sequence from asp Atractaspis engaddensis venom [58456] (1)
    22. Heat-stable enterotoxin (HSE) [58457] (1)
        1. Heat-stable enterotoxin (HSE) [58458] (1)
           1. Heat-stable enterotoxin (HSE) [58459] (2)
              1. Heat-stable enterotoxin [58460]
                 1. Escherichia coli [58461] (3)
              2. Guanylin [58462]
                 1. Human (Homo sapiens) [58463] (4)
    23. Conotoxins [58464] (1)
        1. Conotoxins [58465] (4)
           1. mu-conotoxin [58466] (2)
              1. mu-Conotoxin GIIIa [58467]
                 1. Conus geographus [58468] (4)
              2. mu-Conotoxin GIIIb [58469]
                 1. Conus geographus [58470] (1)
           2. alpha-conotoxin [58471] (4)
              1. alpha-conotoxin PNI1 [58472]
                 1. Conus pennaceus [58473] (1)
              2. alpha-conotoxin PNIB [58474]
                 1. Conus pennaceus [58475] (1)
              3. G1 alpha-conotoxin [58480]
                 1. Conus geographus [58481] (4)
              4. alpha-conotoxin CNIA [58482]
                 1. Conus consors [58483] (1)
           3. Alpha-a-conotoxin [58488] (1)
              1. AA-conotoxin pIVa [58489]
                 1. Conus purpurascens [58490] (1)
           4. psi-conotoxin [58491] (1)
              1. psi-conotoxin pIIIe [58492]
                 1. Conus purpurascens [58493] (1)
    24. Conantokin [58494] (1)
        1. Conantokin [58495] (2)
           1. Conantokin G (conatoxin G) [58496] (1)
              1. Conantokin G (conatoxin G) [58497]
                 1. Conus geographus [58498] (3)
           2. Conantokin-T [58499] (1)
              1. Conantokin-T [58500]
                 1. Conus tulipa [58501] (1)
    25. Kappa-hefutoxin-like [58507] (1)
        1. Immunodominant region of protein G of BRSV [58508] (1)
           1. Immunodominant region of protein G of BRSV [58509] (1)
              1. Immunodominant region of protein G of BRSV [58510]
                 1. Bovine respiratory syncytial virus [58511] (1)
    26. Bradykinin [58512] (1)
        1. Bradykinin [58513] (1)
           1. Bradykinin [58514] (1)
              1. Bradykinin antagonist B-9340 [58515]
                 1. Synthetic [58516] (1)
    27. Transmembrane helical fragments [58517] (1)
        1. Transmembrane helical fragments [58518] (1)
           1. Transmembrane helical fragments [58519] (8)
              1. Bacteriorhodopsin fragments [58520]
                 1. Archaeon Halobacterium halobium [58521] (3)
              2. Band 3 [58524]
                 1. Synthetic peptides based on human band 3 sequence [58525] (7)
              3. Pulmonary surfactant-associated polypeptide C (SP-C) [58526]
                 1. Pig (Sus scrofa) [58527] (1)
              4. beta-Adrenoreceptor [58530]
                 1. Turkey (Meleagris gallopavo) [58531] (1)
              5. F1F0 ATP synthase subunit C fragments [58534]
                 1. Escherichia coli [58535] (1)
              6. alpha-subunit of nicotinic acetylcholine receptor [58538]
                 1. Synthetic, based on Torpedo californica sequence [58539] (1)
              7. Membrane spanning segment 2 (M2) of the acetylcholine receptor [58540]
                 1. Rat (Rattus norvegicus) [58541] (1)
              8. Transmembrane segment 2 of NMDA receptor NR1 [58543]
                 1. Human (Homo sapiens) [58544] (1)
    28. Topogenic peptides [58555] (3)
        1. Ferredoxin chloroplastic transit peptide [58556] (1)
           1. Ferredoxin chloroplastic transit peptide [58557] (1)
              1. Ferredoxin chloroplastic transit peptide [58558]
                 1. Unicellular eukaryote green alga [58559] (1)
        2. Vacuolar targeting peptide from NA-PROPI (residues 29-54) [58560] (1)
           1. Vacuolar targeting peptide from NA-PROPI (residues 29-54) [58561] (1)
              1. Vacuolar targeting peptide from NA-PROPI (residues 29-54) [58562]
                 1. Winged tobacco (Nicotiana alata) [58563] (1)
        3. Microcin leader peptide [58564] (1)
           1. Microcin leader peptide [58565] (1)
              1. Microcin leader peptide [58566]
                 1. Escherichia coli [58567] (1)
    29. Phospholamban fragments [58568] (1)
        1. Phospholamban fragments [58569] (1)
           1. Phospholamban fragments [58570] (1)
              1. Phospholamban fragments [58571]
                 1. Human (Homo sapiens) [58572] (1)
    30. Fragments of apolipoproteins [58579] (1)
        1. Fragments of apolipoproteins [58580] (1)
           1. Fragments of apolipoproteins [58581] (8)
              1. Fragments of apolipoproteins [58582]
                 1. Human (Homo sapiens), synthetic, C-I residues 7-24 [58583] (1)
                 2. Human (Homo sapiens), synthetic, C-I residues 35-53 [58584] (1)
                 3. Human (Homo sapiens), synthetic, C-I residues 1-38 [58585] (1)
                 4. Human (Homo sapiens), synthetic, C-I 57 residues [58586] (1)
                 5. Human (Homo sapiens), synthetic, A-I residues 166-185 [58587] (3)
                 6. Human (Homo sapiens), synthetic, A-I residues 142-187 [58588] (2)
                 7. Human (Homo sapiens), synthetic, E residues 263-286 [58589] (1)
                 8. Human (Homo sapiens), synthetic, E residues 267-289 [58590] (1)
    31. Transactivation protein TAT [58593] (1)
        1. Transactivation protein TAT [58594] (1)
           1. Transactivation protein TAT [58595] (2)
              1. Transactivation protein TAT [58596]
                 1. Equine infectious anemia virus, EIAV [58597] (2)
                 2. Human immunodeficiency virus type 1 [58598] (3)
    32. Proline pipe [58599] (1)
        1. Proline pipe [58600] (1)
           1. Proline pipe [58601] (1)
              1. Tus proline repeat domain (residues 223-244) [58602]
                 1. Escherichia coli [58603] (1)
    33. Amyloid peptides [58604] (1)
        1. Amyloid peptides [58605] (1)
           1. Amyloid peptides [58606] (1)
              1. Alzheimer's disease amyloid beta-peptide [58607]
                 1. Human (Homo sapiens) [58608] (8)
    34. Gelsolin fragment (residues 150-169) [58609] (1)
        1. Gelsolin fragment (residues 150-169) [58610] (1)
           1. Gelsolin fragment (residues 150-169) [58611] (1)
              1. Gelsolin fragment (residues 150-169) [58612]
                 1. Synthetic [58613] (1)
    35. Acetylcholine receptor fragment (residues alpha 67-76) [58614] (1)
        1. Acetylcholine receptor fragment (residues alpha 67-76) [58615] (1)
           1. Acetylcholine receptor fragment (residues alpha 67-76) [58616] (1)
              1. Acetylcholine receptor fragment (residues alpha 67-76) [58617]
                 1. Electric ray (Torpedo californica) [58618] (2)
    36. Thrombomodulin EGF domain fragment (residues 409-426) [58619] (1)
        1. Thrombomodulin EGF domain fragment (residues 409-426) [58620] (1)
           1. Thrombomodulin EGF domain fragment (residues 409-426) [58621] (1)
              1. Thrombomodulin EGF domain fragment (residues 409-426) [58622]
                 1. Human (Homo sapiens) [58623] (3)
    37. Capsid protein major homology region peptide analog [58629] (1)
        1. Capsid protein major homology region peptide analog [58630] (1)
           1. Capsid protein major homology region peptide analog [58631] (1)
              1. Capsid protein major homology region peptide analog [58632]
                 1. Human immunodeficiency virus type 1, HIV-1 [58634] (1)
    38. CD4 and CD8 receptor regions [58635] (1)
        1. CD4 and CD8 receptor regions [58636] (1)
           1. CD4 and CD8 receptor regions [58637] (1)
              1. T-cell surface glycoprotein CD4 [58638]
                 1. Human (Homo sapiens) [58639] (1)
    39. GroES fragments [58645] (1)
        1. GroES fragments [58646] (1)
           1. GroES fragments [58647] (1)
              1. GroES, fragment of mobile loop [58648]
                 1. Escherichia coli [58649] (1)
    40. cAMP and cGMP phosphodiesterase (PDE) fragments [58650] (1)
        1. cAMP and cGMP phosphodiesterase (PDE) fragments [58651] (1)
           1. cAMP and cGMP phosphodiesterase (PDE) fragments [58652] (1)
              1. N-terminal splice region of cAMP phosphodiesterase [58653]
                 1. Rat (Rattus norvegicus) [58654] (1)
    41. HIV-1 Nef protein fragments [58657] (1)
        1. HIV-1 Nef protein fragments [58658] (1)
           1. HIV-1 Nef protein fragments [58659] (1)
              1. HIV-1 Nef protein fragments [58660]
                 1. Synthetic [58661] (1)
    42. Transducin alpha-1 subunit rhodopsin binding domain (res. 340-350) [58677] (1)
        1. Transducin alpha-1 subunit rhodopsin binding domain (res. 340-350) [58678] (1)
           1. Transducin alpha-1 subunit rhodopsin binding domain (res. 340-350) [58679] (1)
              1. Transducin alpha-1 subunit rhodopsin binding domain (res. 340-350) [58680]
                 1. Cow (Bos taurus) [58681] (1)
    43. Human glutathione reductase (HGR) inhibitor [58702] (1)
        1. Human glutathione reductase (HGR) inhibitor [58703] (1)
           1. Human glutathione reductase (HGR) inhibitor [58704] (1)
              1. Human glutathione reductase (HGR) inhibitor [58705]
                 1. Synthetic [58706] (1)
    44. Small subunit C-terminal inhibitory peptide of ribonucleotide reductase [58707] (1)
        1. Small subunit C-terminal inhibitory peptide of ribonucleotide reductase [58708] (1)
           1. Small subunit C-terminal inhibitory peptide of ribonucleotide reductase [58709] (1)
              1. Small subunit C-terminal inhibitory peptide of ribonucleotide reductase [58710]
                 1. Mouse (Mus musculus) [58711] (1)
11. Designed proteins [58788] (11)
    Experimental structures of proteins with essentially non-natural sequences. Not a true class
    1. Hybrid and chimeric proteins [58789] (1)
       1. Hybrid and chimeric proteins [58790] (1)
          1. Hybrid and chimeric proteins [58791] (1)
             1. Hybrid protein between chymotrypsin inhibitor CI-2 and helix E from subtilisin Carlsberg [58792]
                1. Barley (Hordeum vulgare), hiproly strain [58793] (1)
    2. Amphiphilic (amphipathic) alpha helix [58798] (1)
       1. Amphiphilic (amphipathic) alpha helix [58799] (1)
          1. Amphiphilic (amphipathic) alpha helix [58800] (1)
             1. Designed sequence 'Alpha 1' [58801]
                1. Synthetic [58802] (1)
    3. Designed trimeric coiled-coil [100903] (1)
       1. Designed trimeric coiled-coil [100904] (1)
          1. Designed trimeric coiled-coil [100905] (1)
             1. VaLd trimeric coiled-coil [58820]
                1. Synthetic [58821] (1)
    4. Designed four-helix bundle protein [58832] (1)
       1. Designed four-helix bundle protein [58833] (1)
          1. Designed four-helix bundle protein [58834] (1)
             1. DHP1 [58835]
                1. Synthetic non-biological source [58836] (1)
    5. Peptide f (amphiphilic octadecapeptide) [58846] (1)
       1. Peptide f (amphiphilic octadecapeptide) [58847] (1)
          1. Peptide f (amphiphilic octadecapeptide) [58848] (1)
             1. Peptide f (amphiphilic octadecapeptide) [58849]
                1. Synthetic [58850] (1)
    6. Zinc finger design [58856] (1)
       1. Zinc finger design [58857] (1)
          1. Zinc finger design [58858] (1)
             1. Zinc finger with an artificial beta-turn [58861]
                1. Synthetic, based on Homo sapiens sequence [58862] (1)
    7. Protein A Ig(Fc)-binding domain mimics [58863] (1)
       1. Protein A Ig(Fc)-binding domain mimics [58864] (1)
          1. Protein A Ig(Fc)-binding domain mimics [58865] (1)
             1. Protein A Ig(Fc)-binding domain mimics [58866]
                1. Synthetic [58867] (4)
    8. Zinc finger based beta-beta-alpha motif [58868] (1)
       1. Zinc finger based beta-beta-alpha motif [58869] (1)
          1. Zinc finger based beta-beta-alpha motif [58870] (3)
             1. Full sequence design 1 (fsd-1) [58871]
                1. Synthetic [58872] (2)
             2. Computationally designed peptide with a beta-beta-alpha fold selection [58873]
                1. Synthetic [58874] (1)
             3. 23-residue designed metal-free peptide based on the zinc finger domains [58875]
                1. Synthetic [58876] (1)
    9. helix-turn-helix motif [58877] (1)
       1. helix-turn-helix motif [58878] (1)
          1. helix-turn-helix motif [58879] (1)
             1. Alpha-t-alpha, a de novo designed peptide [58880]
                1. Synthetic non-biological sequence [58881] (1)
    10. Right-handed coiled coil [58887] (1)
        1. Right-handed coiled coil [58888] (1)
           1. Right-handed coiled coil [58889] (1)
              1. RH4 designed right-handed coiled coil tetramer [58890]
                 1. Synthetic non-biological sequence [58891] (1)
    11. Octreotide (Sandostatine), a somatostatine analogue [58902] (1)
        1. Octreotide (Sandostatine), a somatostatine analogue [58903] (1)
           1. Octreotide (Sandostatine), a somatostatine analogue [58904] (1)
              1. Octreotide (Sandostatine), a somatostatine analogue [58905]
                 1. Synthetic [58906] (2)