Structural Classification of Proteins
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Changes in domain definitions and classification
Release 1.71 ---> 1.73

Root: scop

Classes:

  1. All alpha proteins [46456] (82)
    1. Globin-like [46457] (1)
      1. Globin-like [46458] (1)
        1. Globins [46463] (16)
          1. Hemoglobin I [46464]
            1. Clam (Lucina pectinata) [46466] (4) picpic
          2. Glycera globin [46467]
            1. Marine bloodworm (Glycera dibranchiata) [46468] (2) picpic
          3. Myoglobin [46469]
            1. Sperm whale (Physeter catodon) [46470] (100) picpic
            2. Sea hare (Aplysia limacina) [46471] (6) picpic
            3. Common seal (Phoca vitulina) [46472] (1) picpic
            4. Pig (Sus scrofa) [46473] (1) picpic
            5. Horse (Equus caballus) [46474] (10) picpic
            6. Human (Homo sapiens) [46475] (1) picpic
            7. Asian elephant (Elephas maximus) [46476] (1) picpic
            8. Loggerhead sea turtle (Caretta caretta) [46477] (2) picpic
            9. Yellowfin tuna (Thunnus albacares) [46478] (1) picpic
          4. Erythrocruorin [46479]
            1. Midge (Chironomus thummi thummi), fraction III [46480] (4) picpic
          5. Leghemoglobin [46481]
            1. Yellow lupin (Lupinus luteus) [46482] (17) picpic
          6. Lamprey globin [46518]
            1. Sea lamprey (Petromyzon marinus) [46519] (1) picpic
          7. Ascaris hemoglobin, domain 1 [46520]
            1. Pig roundworm (Ascaris suum) [46521] (1) picpic
          8. Hemoglobin, different isoforms [46524]
            1. Sea cucumber (Caudina (Molpadia) arenicola) [46525] (2) picpic
    2. Long alpha-hairpin [46556] (3)
      1. GreA transcript cleavage protein, N-terminal domain [46557] (1)
        1. GreA transcript cleavage protein, N-terminal domain [46558] (1)
          1. GreA transcript cleavage protein, N-terminal domain [46559]
            1. Escherichia coli [46560] (1) picpic
      2. Chaperone J-domain [46565] (1)
        1. Chaperone J-domain [46566] (2)
          1. HSP40 [46569]
            1. Human (Homo sapiens) [46570] (1) picpic
          2. DnaJ chaperone, N-terminal (J) domain [46571]
            1. Escherichia coli [46572] (3) picpic
      3. Epsilon subunit of F1F0-ATP synthase C-terminal domain [46604] (1)
        1. Epsilon subunit of F1F0-ATP synthase C-terminal domain [46605] (1)
          1. Epsilon subunit of F1F0-ATP synthase C-terminal domain [46606]
            1. Escherichia coli [46607] (1) picpic
    3. LEM/SAP HeH motif [63450] (1)
      1. Rho termination factor, N-terminal domain [68912] (1)
        1. Rho termination factor, N-terminal domain [68913] (1)
          1. Rho termination factor, N-terminal domain [68914]
            1. Escherichia coli [50295] (2) picpic
    4. Cytochrome c [46625] (1)
      1. Cytochrome c [46626] (1)
        1. monodomain cytochrome c [46627] (21)
          1. Cytochrome c6 (synonym: cytochrome c553) [46628]
            1. Monoraphidium braunii [46630] (3) picpic
            2. Desulfovibrio vulgaris, different strains [46631] (2) picpic
            3. Desulfovibrio desulfuricans [46632] (1) picpic
            4. Chlamydomonas reinhardtii [46633] (2) picpic
            5. Cyanobacterium (Synechococcus elongatus) [46634] (1) picpic
          2. Cytochrome c552 [46636]
            1. Thermus thermophilus [46637] (1) picpic
            2. Hydrogenobacter thermophilus [46640] (1) picpic
            3. Nitrosomonas europaea [46641] (2) picpic
          3. Mitochondrial cytochrome c [46642]
            1. Baker's yeast (Saccharomyces cerevisiae) [46643] (29) picpic
            2. Horse (Equus caballus) [46644] (6) picpic
            3. Rice embryos (Oryza sativa) [46645] (1) picpic
            4. Bonito (Katsuwonus pelamis) [46647] (1) picpic
          4. Cytochrome c2 [46650]
            1. Rhodospirillum rubrum [46651] (2) picpic
            2. Rhodobacter capsulatus [46652] (1) picpic
            3. Rhodobacter sphaeroides [46653] (2) picpic
            4. Rhodopseudomonas viridis [46654] (1) picpic
            5. Paracoccus denitrificans [46657] (2) picpic
          5. Cytochrome c5 [46658]
            1. Azotobacter vinelandii [46659] (1) picpic
          6. Cytochrome c551 [46660]
            1. Pseudomonas stutzeri [46661] (2) picpic
            2. Pseudomonas aeruginosa [46662] (3) picpic
            3. Ectothiorhodospira halophila [46664] (1) picpic
    5. DNA/RNA-binding 3-helical bundle [46688] (6)
      1. Homeodomain-like [46689] (5)
        1. Homeodomain [46690] (10)
          1. Engrailed Homeodomain [46691]
            1. Drosophila melanogaster [46692] (1) picpic
          2. Hepatocyte nuclear factor 1a (LFB1/HNF1) [46697]
            1. Rat (Rattus rattus) [46698] (2) picpic
          3. Oct-1 POU Homeodomain [46699]
            1. Human (Homo sapiens) [46700] (1) picpic
          4. Thyroid transcription factor 1 homeodomain [46703]
            1. Rat (Rattus norvegicus) [46704] (1) picpic
          5. Oct-2 POU Homeodomain [46705]
            1. Human (Homo sapiens) [46706] (1) picpic
          6. Oct-3 POU Homeodomain [46707]
            1. Mouse (Mus musculus) [46708] (1) picpic
          7. Insulin gene enhancer protein isl-1 [46714]
            1. Rat (Rattus norvegicus) [46715] (1) picpic
          8. Antennapedia Homeodomain [46716]
            1. Drosophila melanogaster [46717] (3) picpic
          9. Fushi Tarazu protein [46722]
            1. Fruit fly (Drosophila melanogaster) [46723] (1) picpic
          10. VND/NK-2 protein [46724]
            1. Fruit fly (Drosophila melanogaster) [46725] (1) picpic
        2. Recombinase DNA-binding domain [46728] (3)
          1. gamma,delta resolvase (C-terminal domain) [46731]
            1. Escherichia coli [46732] (2) picpic
          2. Ibeta subdomain of the mu end DNA-binding domain of phage mu transposase [46735]
            1. Bacteriophage mu [46736] (2) picpic
          3. Transposase [46737]
            1. Bacteriophage mu [46738] (2) picpic
        3. Myb/SANT domain [46739] (2)
          1. c-Myb, DNA-binding domain [46740]
            1. Mouse (Mus musculus) [46742] (8) picpic
          2. b-Myb DNA binding domain [46743]
            1. Chicken (Gallus gallus) [46744] (2) picpic
        4. DNA-binding domain of telomeric protein [46745] (1)
          1. DNA-binding domain of human telomeric protein, hTRF1 [46746]
            1. Human (Homo sapiens) [46747] (1) picpic
        5. Tetracyclin repressor-like, N-terminal domain [46764] (1)
          1. Tetracyclin repressor (Tet-repressor, TetR) [46765]
            1. Escherichia coli [46766] (6) picpic
      2. Methylated DNA-protein cysteine methyltransferase, C-terminal domain [46767] (1)
        1. Methylated DNA-protein cysteine methyltransferase, C-terminal domain [46768] (1)
          1. Ada DNA repair protein [46769]
            1. Escherichia coli [46770] (1) picpic
      3. "Winged helix" DNA-binding domain [46785] (11)
        1. Biotin repressor-like [46786] (1)
          1. Biotin repressor, N-terminal domain [46787]
            1. Escherichia coli [46788] (2) picpic
        2. LexA repressor, N-terminal DNA-binding domain [46789] (1)
          1. LexA repressor, N-terminal DNA-binding domain [46790]
            1. Escherichia coli [46791] (2) picpic
        3. Arginine repressor (ArgR), N-terminal DNA-binding domain [46792] (1)
          1. Arginine repressor (ArgR), N-terminal DNA-binding domain [46793]
            1. Escherichia coli [46794] (1) picpic
        4. Plant O-methyltransferase, N-terminal domain [63475] (1)
          1. Carminomycin 4-O-methyltransferase [109667]
            1. Streptomyces peucetius [109668] (4) picpic
        5. Linker histone H1/H5 [46827] (1)
          1. Histone H1, globular domain [46830]
            1. Chicken (Gallus gallus) [46831] (1) picpic
        6. Forkhead DNA-binding domain [46832] (1)
          1. Genesis [46837]
            1. Rat (Rattus norvegicus) [46838] (1) picpic
        7. DNA-binding domain from rap30 [46841] (1)
          1. DNA-binding domain from rap30 [46842]
            1. Human (Homo sapiens) [46843] (2) picpic
        8. Heat-shock transcription factor [46873] (2)
          1. Heat-shock transcription factor [46874]
            1. Drosophila melanogaster [46875] (2) picpic
            2. Milk yeast (Kluyveromyces lactis) [46876] (2) picpic
        9. Interferon regulatory factor [46877] (1)
          1. Interferon regulatory factor-2, IRF-2 [46880]
            1. Mouse (Mus musculus) [46881] (2) picpic
        10. Iron-dependent repressor protein [46882] (1)
          1. Diphtheria toxin repressor (DtxR) [46883]
            1. Corynebacterium diphtheriae [46884] (4) picpic
        11. Methionine aminopeptidase, insert domain [46887] (2)
          1. Methionine aminopeptidase, insert domain [46888]
            1. Archaeon Pyrococcus furiosus [46889] (1) picpic
            2. Human (Homo sapiens) [46890] (3) picpic
      4. C-terminal effector domain of the bipartite response regulators [46894] (2)
        1. PhoB-like [46895] (1)
          1. OmpR [46896]
            1. Escherichia coli [46897] (2) picpic
        2. GerE-like (LuxR/UhpA family of transcriptional regulators) [46900] (1)
          1. Nitrate/nitrite response regulator (NarL) [46901]
            1. Escherichia coli [46902] (1) picpic
      5. TrpR-like [48295] (1)
        1. Trp repressor, TrpR [48296] (1)
          1. Trp repressor, TrpR [48297]
            1. Escherichia coli [48298] (1) picpic
      6. Ribosomal protein L11, C-terminal domain [46906] (1)
        1. Ribosomal protein L11, C-terminal domain [46907] (1)
          1. Ribosomal protein L11, C-terminal domain [46908]
            1. Bacillus stearothermophilus [46909] (5) picpic
    6. Another 3-helical bundle [81602] (1)
      1. Protein serine/threonine phosphatase 2C, C-terminal domain [81601] (1)
        1. Protein serine/threonine phosphatase 2C, C-terminal domain [81600] (1)
          1. Protein serine/threonine phosphatase 2C, C-terminal domain [81599]
            1. Human (Homo sapiens) [81598] (1) picpic
    7. RuvA C-terminal domain-like [46928] (2)
      1. DNA helicase RuvA subunit, C-terminal domain [46929] (1)
        1. DNA helicase RuvA subunit, C-terminal domain [46930] (1)
          1. DNA helicase RuvA subunit, C-terminal domain [46931]
            1. Escherichia coli [46932] (2) picpic
      2. CRAL/TRIO N-terminal domain [46938] (1)
        1. CRAL/TRIO N-terminal domain [46939] (1)
          1. N-terminal domain of phosphatidylinositol transfer protein sec14p [46940]
            1. Baker's yeast (Saccharomyces cerevisiae) [46941] (1) picpic
    8. Putative DNA-binding domain [46954] (1)
      1. Putative DNA-binding domain [46955] (2)
        1. DNA repair factor XPA DNA- and RPA-binding domain, C-terminal subdomain [46959] (1)
          1. DNA repair factor XPA DNA- and RPA-binding domain, C-terminal subdomain [46960]
            1. Human (Homo sapiens) [46961] (1) picpic
        2. Excisionase-like [46891] (1)
          1. mu transposase, DNA-binding domain [46892]
            1. Bacteriophage mu [46893] (2) picpic
    9. Spectrin repeat-like [46965] (1)
      1. Spectrin repeat [46966] (1)
        1. Spectrin repeat [46967] (1)
          1. Spectrin alpha chain [46968]
            1. Chicken (Gallus gallus) [46970] (1) picpic
    10. immunoglobulin/albumin-binding domain-like [46996] (1)
      1. Bacterial immunoglobulin/albumin-binding domains [46997] (2)
        1. Immunoglobulin-binding protein A modules [46998] (1)
          1. Immunoglobulin-binding protein A modules [46999]
            1. Staphylococcus aureus [47000] (6) picpic
        2. GA module, an albumin-binding domain [47001] (1)
          1. PAB [47002]
            1. Peptostreptococcus magnus [47003] (2) picpic
    11. Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex [47004] (1)
      1. Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex [47005] (1)
        1. Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex [47006] (2)
          1. E3-binding domain of dihydrolipoamide succinyltransferase [47009]
            1. Escherichia coli [47010] (2) picpic
          2. E3/E1 binding domain of dihydrolipoyl acetyltransferase [47011]
            1. Bacillus stearothermophilus [47012] (2) picpic
    12. Protozoan pheromone-like [47013] (1)
      1. Protozoan pheromone proteins [47014] (1)
        1. Protozoan pheromone proteins [47015] (4)
          1. ER-1 [47016]
            1. Euplotes raikovi [47017] (2) picpic
          2. ER-2 [47018]
            1. Euplotes raikovi [47019] (1) picpic
          3. ER-10 [47020]
            1. Euplotes raikovi [47021] (1) picpic
          4. ER-11 [47022]
            1. Euplotes raikovi [47023] (1) picpic
    13. Acyl-CoA binding protein-like [47026] (1)
      1. Acyl-CoA binding protein [47027] (1)
        1. Acyl-CoA binding protein [47028] (1)
          1. Acyl-CoA binding protein [47029]
            1. Cow (Bos taurus) [47030] (2) picpic
    14. alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 [47044] (1)
      1. alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 [47045] (1)
        1. alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 [47046] (1)
          1. alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 [47047]
            1. Human (Homo sapiens) [47048] (2) picpic
    15. VHP, Villin headpiece domain [47049] (1)
      1. VHP, Villin headpiece domain [47050] (1)
        1. VHP, Villin headpiece domain [47051] (1)
          1. Villin [47052]
            1. Chicken (Gallus gallus) [47053] (1) picpic
    16. S15/NS1 RNA-binding domain [47059] (1)
      1. S15/NS1 RNA-binding domain [47060] (2)
        1. N-terminal, RNA-binding domain of nonstructural protein NS1 [47061] (1)
          1. N-terminal, RNA-binding domain of nonstructural protein NS1 [47062]
            1. Influenza A virus [47063] (1) picpic
        2. Ribosomal protein S15 [47064] (2)
          1. Ribosomal protein S15 [47065]
            1. Bacillus stearothermophilus [47066] (1) picpic
            2. Thermus thermophilus [47067] (1) picpic
    17. T4 endonuclease V [47076] (1)
      1. T4 endonuclease V [47077] (1)
        1. T4 endonuclease V [47078] (1)
          1. T4 endonuclease V [47079]
            1. Bacteriophage T4 [47080] (4) picpic
    18. Fertilization protein [47081] (1)
      1. Fertilization protein [47082] (1)
        1. Fertilization protein [47083] (1)
          1. Lysin [47084]
            1. Red abalone (Haliotis rufescens) [47085] (1) picpic
    19. PGBD-like [47089] (1)
      1. PGBD-like [47090] (2)
        1. Peptidoglycan binding domain, PGBD [47091] (1)
          1. Zn2+ DD-carboxypeptidase, N-terminal domain [47092]
            1. Streptomyces albus G [47093] (1) picpic
        2. MMP N-terminal domain [63427] (1)
          1. Stromelysin-1 (MMP-3) [63429]
            1. Human (Homo sapiens), fibroblast [63431] (1) picpic
    20. HMG-box [47094] (1)
      1. HMG-box [47095] (1)
        1. HMG-box [47096] (3)
          1. High mobility group protein 1, HMG1 [47097]
            1. Rat (Rattus norvegicus) [47098] (3) picpic
            2. Hamster (Cricetulus griseus) [47099] (4) picpic
          2. HMG-D [47100]
            1. Drosophila melanogaster [47101] (1) picpic
    21. Histone-fold [47112] (1)
      1. Histone-fold [47113] (1)
        1. Archaeal histone [47129] (2)
          1. Archaeal histone [68897]
            1. Archaeon Methanothermus fervidus, histone A [68895] (1) picpic
            2. Archaeon Methanothermus fervidus, histone B [68896] (1) picpic
    22. Four-helical up-and-down bundle [47161] (6)
      1. Apolipoprotein [47162] (1)
        1. Apolipoprotein [47163] (3)
          1. Apolipoprotein E [88703]
            1. Human (Homo sapiens), E3 [47165] (2) picpic
            2. Human (Homo sapiens), E2 [47167] (2) picpic
            3. Human (Homo sapiens), E4 [47169] (1) picpic
      2. Aspartate receptor, ligand-binding domain [47170] (1)
        1. Aspartate receptor, ligand-binding domain [47171] (2)
          1. Aspartate receptor, ligand-binding domain [47172]
            1. Escherichia coli [47173] (1) picpic
            2. Salmonella typhimurium [47174] (3) picpic
      3. Cytochromes [47175] (2)
        1. Cytochrome b562 [47176] (1)
          1. Cytochrome b562 [47177]
            1. Escherichia coli [47178] (1) picpic
        2. Cytochrome c'-like [47179] (3)
          1. Cytochrome c' [47180]
            1. Alcaligenes denitrificans [47183] (1) picpic
            2. Alcaligenes sp. [47184] (1) picpic
            3. Rhodobacter capsulatus [47186] (2) picpic
      4. Hemerythrin [47188] (1)
        1. Hemerythrin [47189] (2)
          1. Hemerythrin [47190]
            1. Phascolopsis gouldii [47192] (1) picpic
          2. Myohemerythin [47193]
            1. Sipunculan worm (Themiste zostericola) [47194] (3) picpic
      5. Histidine-containing phosphotransfer domain, HPT domain [47226] (1)
        1. Aerobic respiration control sensor protein, ArcB [47227] (1)
          1. Aerobic respiration control sensor protein, ArcB [47228]
            1. Escherichia coli [47229] (2) picpic
      6. Domain of the SRP/SRP receptor G-proteins [47364] (1)
        1. Domain of the SRP/SRP receptor G-proteins [47365] (2)
          1. Signal sequence recognition protein Ffh [47366]
            1. Thermus aquaticus [47367] (3) picpic
          2. Signal recognition particle receptor, FtsY [47368]
            1. Escherichia coli [47369] (1) picpic
    23. Ferritin-like [47239] (1)
      1. Ferritin-like [47240] (2)
        1. Ferritin [47241] (4)
          1. Rubrerythrin, N-terminal domain [47242]
            1. Desulfovibrio vulgaris [47243] (1) picpic
          2. (Apo)ferritin [47246]
            1. Human (Homo sapiens), H chain [47247] (2) picpic
            2. Horse (Equus caballus), L chain [47248] (4) picpic
            3. Bullfrog (Rana catesbeiana) [47249] (6) picpic
        2. Ribonucleotide reductase-like [47253] (1)
          1. Ribonucleotide reductase R2 [47257]
            1. Mouse (Mus musculus) [47260] (1) picpic
    24. 4-helical cytokines [47265] (1)
      1. 4-helical cytokines [47266] (3)
        1. Long-chain cytokines [47267] (7)
          1. Granulocyte-colony stimulating factor (G-CSF) [47268]
            1. Human (Homo sapiens) [47269] (1) picpic
            2. Cow (Bos taurus) [47270] (1) picpic
            3. Dog (Canis familiaris) [47271] (1) picpic
          2. Interleukin-6 [47272]
            1. Human (Homo sapiens) [47273] (3) picpic
          3. Leukemia inhibitory factor (LIF) [47274]
            1. Mouse (Mus musculus) [47275] (2) picpic
          4. Growth hormone, somatotropin [47276]
            1. Human (Homo sapiens) [47277] (2) picpic
          5. Leptin (obesity protein) [47282]
            1. Human (Homo sapiens) [47283] (1) picpic
        2. Short-chain cytokines [47286] (3)
          1. Interleukin-4 (IL-4) [47291]
            1. Human (Homo sapiens) [47292] (11) picpic
          2. Interleukin-2 (IL-2) [47301]
            1. Human (Homo sapiens) [47302] (1) picpic
          3. Interleukin-3 (IL-3) [47303]
            1. Human (Homo sapiens) [47304] (1) picpic
        3. Interferons/interleukin-10 (IL-10) [47305] (6)
          1. Interleukin-10 (cytokine synthesis inhibitory factor, CSIF) [47306]
            1. Human (Homo sapiens) [47307] (3) picpic
            2. Epstein-Barr virus [47308] (1) picpic
          2. Interferon-beta [47309]
            1. Mouse (Mus musculus) [47311] (1) picpic
          3. Interferon-alpha 2a [47314]
            1. Human (Homo sapiens) [47315] (1) picpic
          4. Interferon-tau [47316]
            1. Sheep (Ovis aries) [47317] (1) picpic
          5. Interferon-gamma [47318]
            1. Rabbit (Oryctolagus cuniculus) [47321] (1) picpic
    25. Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47322] (1)
      1. Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47323] (1)
        1. Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47324] (2)
          1. Methionyl-tRNA synthetase (MetRS) [47325]
            1. Thermus thermophilus [47326] (1) picpic
          2. Isoleucyl-tRNA synthetase (IleRS) [47328]
            1. Thermus thermophilus [47329] (1) picpic
    26. Acyl carrier protein-like [47335] (3)
      1. ACP-like [47336] (1)
        1. Acyl-carrier protein (ACP) [47337] (2)
          1. Acyl carrier protein [47338]
            1. Escherichia coli [47339] (1) picpic
          2. Actinorhodin polyketide synthase acyl carrier protein, ACT ACP [47340]
            1. Streptomyces coelicolor, A3(2) [47341] (2) picpic
      2. Colicin E immunity proteins [47345] (1)
        1. Colicin E immunity proteins [47346] (2)
          1. ImmE7 protein (Im7) [47347]
            1. Escherichia coli [47348] (2) picpic
          2. ImmE9 protein (Im9) [47351]
            1. Escherichia coli [47352] (2) picpic
      3. Retrovirus capsid protein C-terminal domain [47353] (1)
        1. Retrovirus capsid protein C-terminal domain [47354] (2)
          1. EIAV capsid protein p26 [47355]
            1. Equine infectious anemia virus [47356] (1) picpic
          2. HIV capsid protein, dimerisation domain [47359]
            1. Human immunodeficiency virus type 1 [47360] (4) picpic
    27. ROP-like [47379] (1)
      1. ROP protein [47380] (1)
        1. ROP protein [47381] (1)
          1. ROP protein [47382]
            1. Escherichia coli [47383] (3) picpic
    28. lambda repressor-like DNA-binding domains [47412] (1)
      1. lambda repressor-like DNA-binding domains [47413] (3)
        1. POU-specific domain [47414] (1)
          1. Oct-1 [47415]
            1. Human (Homo sapiens) [47416] (1) picpic
        2. Phage repressors [47419] (6)
          1. lambda C1 repressor, DNA-binding domain [47420]
            1. Bacteriophage lambda [47421] (1) picpic
          2. 434 C1 repressor, DNA-binding domain [47422]
            1. Bacteriophage 434 [47423] (4) picpic
          3. cro 434 [47424]
            1. Bacteriophage 434 [47425] (2) picpic
          4. P22 C2 repressor, DNA-binding domain [47426]
            1. Salmonella bacteriophage P22 [47427] (1) picpic
          5. cro lambda repressor [47428]
            1. Bacteriophage lambda [47429] (2) picpic
          6. Ner [47430]
            1. Bacteriophage mu [47431] (2) picpic
        3. GalR/LacI-like bacterial regulator [47438] (3)
          1. Purine repressor (PurR), N-terminal domain [47439]
            1. Escherichia coli [47440] (2) picpic
          2. Lac repressor (LacR), N-terminal domain [47441]
            1. Escherichia coli [47442] (1) picpic
          3. Fructose repressor (FruR), N-terminal domain [47443]
            1. Escherichia coli [47444] (2) picpic
    29. EF Hand-like [47472] (2)
      1. EF-hand [47473] (6)
        1. Calbindin D9K [47474] (2)
          1. Calbindin D9K [47475]
            1. Cow (Bos taurus) [47476] (8) picpic
            2. Pig (Sus scrofa) [47477] (1) picpic
        2. S100 proteins [47478] (2)
          1. Calcyclin (S100) [47479]
            1. Cow (Bos taurus), s100b [47482] (1) picpic
            2. Human (Homo sapiens), psoriasin s100a7 [47485] (1) picpic
        3. Osteonectin [47489] (1)
          1. C-terminal (EC) domain of BM-40/SPARC/osteonectin [47490]
            1. Human (Homo sapiens) [47491] (1) picpic
        4. Parvalbumin [47492] (5)
          1. Oncomodulin [47493]
            1. Rat (Rattus norvegicus) [47494] (2) picpic
          2. Parvalbumin [47495]
            1. Carp (Cyprinus carpio) [47496] (3) picpic
            2. Pike (Esox lucius) [47497] (7) picpic
            3. Leopard shark (Triakis semifasciata) [47498] (1) picpic
            4. Silver hake (Merluccius bilinearis) [47500] (1) picpic
        5. Calmodulin-like [47502] (13)
          1. Troponin C [47503]
            1. Chicken (Gallus gallus) [47504] (16) picpic
            2. Turkey (Meleagris gallopavo) [47505] (2) picpic
            3. Rabbit (Oryctolagus cuniculus) [47506] (3) picpic
            4. Human (Homo sapiens), cardiac isoform [47508] (2) picpic
          2. Sarcoplasmic calcium-binding protein [47509]
            1. Amphioxus (Branchiostoma lanceolatum) [47511] (1) picpic
          3. Calmodulin [47516]
            1. Human (Homo sapiens) [47517] (2) picpic
            2. Cow (Bos taurus) [47518] (6) picpic
            3. Rat (Rattus rattus) [47519] (1) picpic
            4. Chicken (Gallus gallus) [47520] (1) picpic
            5. African frog (Xenopus laevis) [47521] (4) picpic
            6. Drosophila melanogaster [47522] (1) picpic
            7. Ciliate (Paramecium tetraurelia) [47523] (2) picpic
          4. Recoverin [47533]
            1. Cow (Bos taurus) [47534] (3) picpic
        6. Eps15 homology domain (EH domain) [47543] (1)
          1. Eps15 [47544]
            1. Human (Homo sapiens) [47546] (1) picpic
      2. Cloroperoxidase [47571] (1)
        1. Cloroperoxidase [47572] (1)
          1. Cloroperoxidase [47573]
            1. Fungus (Caldariomyces fumago) [47574] (4) picpic
    30. CH domain-like [47575] (1)
      1. Calponin-homology domain, CH-domain [47576] (1)
        1. Calponin-homology domain, CH-domain [47577] (2)
          1. beta-spectrin [47578]
            1. Human (Homo sapiens) [47579] (1) picpic
          2. Fimbrin (Plastin), actin-crosslinking domain [47580]
            1. Human (Homo sapiens) [47581] (2) picpic
    31. Domain of poly(ADP-ribose) polymerase [47586] (1)
      1. Domain of poly(ADP-ribose) polymerase [47587] (1)
        1. Domain of poly(ADP-ribose) polymerase [47588] (1)
          1. Domain of poly(ADP-ribose) polymerase [47589]
            1. Chicken (Gallus gallus) [47590] (6) picpic
    32. Glutathione S-transferase (GST), C-terminal domain [47615] (1)
      1. Glutathione S-transferase (GST), C-terminal domain [47616] (1)
        1. Glutathione S-transferase (GST), C-terminal domain [47617] (6)
          1. Class mu GST [81348]
            1. Human (Homo sapiens) [47622] (1) picpic
          2. Class alpha GST [81349]
            1. Schistosoma japonicum [47633] (4) picpic
            2. Fasciola hepatica [47634] (1) picpic
          3. Class sigma GST [81351]
            1. Squid (Ommastrephes sloani pacificus) [47631] (2) picpic
          4. Class phi GST [81356]
            1. Maize (Zea mays), type III [47637] (1) picpic
          5. Class beta GST [81357]
            1. Proteus mirabilis [47639] (1) picpic
    33. Methionine synthase domain-like [47643] (1)
      1. Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain [47648] (1)
        1. Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain [47649] (1)
          1. Thymidine phosphorylase [47650]
            1. Escherichia coli [47651] (3) picpic
    34. Anaphylotoxins (complement system) [47685] (1)
      1. Anaphylotoxins (complement system) [47686] (1)
        1. Anaphylotoxins (complement system) [47687] (2)
          1. C5a anaphylotoxin [47688]
            1. Human (Homo sapiens) [47689] (1) picpic
            2. Pig (Sus scrofa domestica) [47690] (1) picpic
    35. Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [47698] (1)
      1. Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [47699] (2)
        1. Plant lipid-transfer and hydrophobic proteins [47700] (4)
          1. Soybean hydrophobic protein [47701]
            1. Soybean (Glycine max) [47702] (1) picpic
          2. Plant non-specific lipid-transfer protein (ns-LTP, ns-LTP1) [47703]
            1. Barley (Hordeum vulgare) [47705] (3) picpic
            2. Maize (Zea mays) [47706] (3) picpic
            3. Rice (Oryza sativa) [47707] (2) picpic
        2. Proteinase/alpha-amylase inhibitors [47708] (2)
          1. Trypsin/alpha-amylase inhibitor RBI [47711]
            1. Ragi (Elucine coracana gaertneri), seeds [47712] (1) picpic
          2. Hageman factor/amylase inhibitor [47713]
            1. Maize (Zea mays) [47714] (2) picpic
    36. p53 tetramerization domain [47718] (1)
      1. p53 tetramerization domain [47719] (1)
        1. p53 tetramerization domain [47720] (1)
          1. p53 tetramerization domain [47721]
            1. Human (Homo sapiens) [47722] (1) picpic
    37. Domain of early E2A DNA-binding protein, ADDBP [47723] (1)
      1. Domain of early E2A DNA-binding protein, ADDBP [47724] (1)
        1. Domain of early E2A DNA-binding protein, ADDBP [47725] (1)
          1. Domain of early E2A DNA-binding protein, ADDBP [47726]
            1. Human adenovirus type 5 [47727] (2) picpic
    38. Chemotaxis receptor methyltransferase CheR, N-terminal domain [47756] (1)
      1. Chemotaxis receptor methyltransferase CheR, N-terminal domain [47757] (1)
        1. Chemotaxis receptor methyltransferase CheR, N-terminal domain [47758] (1)
          1. Chemotaxis receptor methyltransferase CheR, N-terminal domain [47759]
            1. Salmonella typhimurium [47760] (1) picpic
    39. SAM domain-like [47768] (8)
      1. SAM/Pointed domain [47769] (2)
        1. Pointed domain [47770] (1)
          1. Ets-1 transcription factor pointed domain [47771]
            1. Mouse (Mus musculus) [47772] (1) picpic
        2. SAM (sterile alpha motif) domain [47773] (1)
          1. EphB2 receptor [47776]
            1. Chicken (Gallus gallus) [47778] (1) picpic
      2. RuvA domain 2-like [47781] (1)
        1. DNA helicase RuvA subunit, middle domain [47782] (1)
          1. DNA helicase RuvA subunit, middle domain [47783]
            1. Escherichia coli [47784] (2) picpic
      3. C-terminal domain of RNA polymerase alpha subunit [47789] (1)
        1. C-terminal domain of RNA polymerase alpha subunit [47790] (1)
          1. C-terminal domain of RNA polymerase alpha subunit [47791]
            1. Escherichia coli [47792] (1) picpic
      4. DNA polymerase beta, N-terminal domain-like [47802] (1)
        1. DNA polymerase beta, N-terminal domain-like [47803] (1)
          1. DNA polymerase beta, N-terminal (8 kD)-domain [47804]
            1. Rat (Rattus norvegicus) [47806] (4) picpic
      5. DNA polymerase beta-like, second domain [81585] (1)
        1. DNA polymerase beta-like, second domain [81584] (1)
          1. DNA polymerase beta [81579]
            1. Rat (Rattus norvegicus) [81577] (12) picpic
      6. 5' to 3' exonuclease, C-terminal subdomain [47807] (1)
        1. 5' to 3' exonuclease, C-terminal subdomain [47808] (3)
          1. T4 RNase H [47809]
            1. Bacteriophage T4 [47810] (1) picpic
          2. 5' to 3' exonuclease domain of DNA polymerase Taq [47811]
            1. Thermus aquaticus [47812] (1) picpic
          3. Flap endonuclease-1 (Fen-1 nuclease) [47815]
            1. Archaeon Methanococcus jannaschii [47816] (2) picpic
      7. lambda integrase-like, N-terminal domain [47823] (1)
        1. lambda integrase-like, N-terminal domain [47824] (1)
          1. Recombinase XerD [47827]
            1. Escherichia coli [47828] (1) picpic
      8. Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain [47831] (1)
        1. Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain [47832] (1)
          1. Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain [47833]
            1. Escherichia coli [47834] (7) picpic
    40. Retroviral matrix proteins [47835] (1)
      1. Retroviral matrix proteins [47836] (4)
        1. Immunodeficiency virus matrix proteins [47837] (1)
          1. HIV-1 matrix protein (HIV-1 MA, HIVp17, p17, MA) [47838]
            1. Human immunodeficiency virus type 1 [47839] (2) picpic
        2. HTLV-II matrix protein [47842] (1)
          1. HTLV-II matrix protein [47843]
            1. Human T-cell leukemia virus type 2 [47844] (1) picpic
        3. Mason-Pfizer monkey virus matrix protein [47845] (1)
          1. Mason-Pfizer monkey virus matrix protein [47846]
            1. Simian Mason-Pfizer virus [47847] (1) picpic
        4. GAG polyprotein M-domain [47848] (1)
          1. GAG polyprotein M-domain [47849]
            1. Rous sarcoma virus [47850] (1) picpic
    41. Apolipophorin-III [47856] (1)
      1. Apolipophorin-III [47857] (1)
        1. Apolipophorin-III [47858] (1)
          1. Apolipophorin-III [47859]
            1. African locust (Locusta migratoria) [47860] (1) picpic
    42. Saposin-like [47861] (1)
      1. Saposin [47862] (1)
        1. NKL-like [47863] (1)
          1. NK-lysin, NKL [47864]
            1. Pig (Sus scrofa) [47865] (1) picpic
    43. Annexin [47873] (1)
      1. Annexin [47874] (1)
        1. Annexin [47875] (7)
          1. Annexin I [47876]
            1. Human (Homo sapiens) [47877] (1) picpic
          2. Annexin III [47879]
            1. Human (Homo sapiens) [47880] (2) picpic
          3. Annexin IV [47881]
            1. Cow (Bos taurus) [47882] (2) picpic
          4. Annexin V [47883]
            1. Chicken (Gallus gallus) [47884] (1) picpic
            2. Human (Homo sapiens) [47885] (6) picpic
            3. Rat (Rattus norvegicus) [47886] (9) picpic
          5. Annexin VI [47887]
            1. Cow (Bos taurus) [47888] (2) picpic
    44. Transducin (alpha subunit), insertion domain [47894] (1)
      1. Transducin (alpha subunit), insertion domain [47895] (1)
        1. Transducin (alpha subunit), insertion domain [47896] (2)
          1. Transducin (alpha subunit), insertion domain [47897]
            1. Cow (Bos taurus) [47898] (1) picpic
            2. Rat (Rattus norvegicus) [47899] (10) picpic
    45. N-terminal domain of the delta subunit of the F1F0-ATP synthase [47927] (1)
      1. N-terminal domain of the delta subunit of the F1F0-ATP synthase [47928] (1)
        1. N-terminal domain of the delta subunit of the F1F0-ATP synthase [47929] (1)
          1. N-terminal domain of the delta subunit of the F1F0-ATP synthase [47930]
            1. Escherichia coli [47931] (1) picpic
    46. Retrovirus capsid protein, N-terminal core domain [47942] (1)
      1. Retrovirus capsid protein, N-terminal core domain [47943] (1)
        1. Retrovirus capsid protein, N-terminal core domain [47944] (1)
          1. EIAV capsid protein p26 [47947]
            1. Equine infectious anemia virus [47948] (1) picpic
    47. Cyclin-like [47953] (1)
      1. Cyclin-like [47954] (3)
        1. Cyclin [47955] (2)
          1. Cyclin A [47956]
            1. Cow (Bos taurus) [47958] (2) picpic
          2. Cyclin H (mcs2) [47959]
            1. Human (Homo sapiens) [47960] (4) picpic
        2. Transcription factor IIB (TFIIB), core domain [47965] (1)
          1. Transcription factor IIB (TFIIB), core domain [47966]
            1. Human (Homo sapiens) [47967] (2) picpic
        3. Retinoblastoma tumor suppressor domains [47969] (1)
          1. Retinoblastoma tumor suppressor domains [47970]
            1. Human (Homo sapiens) [47971] (1) picpic
    48. Ribosomal protein S7 [47972] (1)
      1. Ribosomal protein S7 [47973] (1)
        1. Ribosomal protein S7 [47974] (2)
          1. Ribosomal protein S7 [47975]
            1. Bacillus stearothermophilus [47976] (1) picpic
            2. Thermus thermophilus [47977] (1) picpic
    49. DNA polymerase III clamp loader subunits, C-terminal domain [48018] (1)
      1. DNA polymerase III clamp loader subunits, C-terminal domain [48019] (1)
        1. DNA polymerase III clamp loader subunits, C-terminal domain [48020] (3)
          1. delta prime subunit [48021]
            1. Escherichia coli [48022] (1) picpic
          2. delta subunit [63580]
            1. Escherichia coli [63581] (4) picpic
          3. Replication factor C4 [109896]
            1. Baker's yeast (Saccharomyces cerevisiae) [109897] (1) picpic
    50. Iron-dependent repressor protein, dimerization domain [47978] (1)
      1. Iron-dependent repressor protein, dimerization domain [47979] (1)
        1. Iron-dependent repressor protein, dimerization domain [47980] (1)
          1. Diphtheria toxin repressor (DtxR) [47981]
            1. Corynebacterium diphtheriae [47982] (4) picpic
    51. DEATH domain [47985] (1)
      1. DEATH domain [47986] (3)
        1. DEATH domain, DD [81312] (2)
          1. p75 low affinity neurotrophin receptor [47988]
            1. Rat (Rattus norvegicus) [47989] (1) picpic
          2. Fas [47990]
            1. Human (Homo sapiens) [47991] (1) picpic
        2. DEATH effector domain, DED [81388] (1)
          1. FADD (Mort1) [81387]
            1. Human (Homo sapiens) [81386] (2) picpic
        3. Caspase recruitment domain, CARD [81313] (1)
          1. Raidd CARD domain [47995]
            1. Human (Homo sapiens) [47996] (1) picpic
    52. Guanido kinase N-terminal domain [48033] (1)
      1. Guanido kinase N-terminal domain [48034] (1)
        1. Guanido kinase N-terminal domain [48035] (1)
          1. Arginine kinase, N-domain [48042]
            1. Horseshoe crab (Limulus polyphemus) [48043] (1) picpic
    53. Hemocyanin, N-terminal domain [48049] (1)
      1. Hemocyanin, N-terminal domain [48050] (1)
        1. Hemocyanin, N-terminal domain [48051] (2)
          1. Hemocyanin, N-terminal domain [48052]
            1. Horseshoe crab (Limulus polyphemus) [48053] (4) picpic
            2. Spiny lobster (Panulirus interruptus) [48054] (7) picpic
    54. Di-copper centre-containing domain [48055] (1)
      1. Di-copper centre-containing domain [48056] (1)
        1. Hemocyanin middle domain [48057] (2)
          1. Arthropod hemocyanin [48058]
            1. Horseshoe crab (Limulus polyphemus) [48059] (4) picpic
            2. Spiny lobster (Panulirus interruptus) [48060] (7) picpic
    55. Transcription factor STAT-4 N-domain [48091] (1)
      1. Transcription factor STAT-4 N-domain [48092] (1)
        1. Transcription factor STAT-4 N-domain [48093] (1)
          1. Transcription factor STAT-4 N-domain [48094]
            1. Mouse (Mus musculus) [48095] (1) picpic
    56. Heme-dependent peroxidases [48112] (1)
      1. Heme-dependent peroxidases [48113] (2)
        1. CCP-like [48114] (5)
          1. Fungal peroxidase (ligninase) [88935]
            1. White rot basidiomycete (Phanerochaete chrysosporium) [48116] (1) picpic
            2. Arthromyces ramosus [48118] (9) picpic
            3. Basidomycetos fungus (Phanerochaete chrysosporium) [48122] (3) picpic
          2. Cytochrome c peroxidase, CCP [48119]
            1. Baker's yeast (Saccharomyces cerevisiae) [48120] (59) picpic
          3. Plant peroxidase [48125]
            1. Barley (Hordeum vulgare), peroxidase 1 [48129] (1) picpic
        2. Myeloperoxidase-like [48132] (1)
          1. Prostaglandin H2 synthase [48136]
            1. Sheep (Ovis aries) [48137] (1) picpic
    57. DNA-glycosylase [48149] (1)
      1. DNA-glycosylase [48150] (2)
        1. Endonuclease III [48151] (1)
          1. Endonuclease III [48152]
            1. Escherichia coli [48153] (1) picpic
        2. Mismatch glycosylase [48154] (1)
          1. Catalytic domain of MutY [48155]
            1. Escherichia coli [48156] (1) picpic
    58. An anticodon-binding domain of class I aminoacyl-tRNA synthetases [48162] (1)
      1. An anticodon-binding domain of class I aminoacyl-tRNA synthetases [48163] (1)
        1. C-terminal domain of glutamyl-tRNA synthetase (GluRS) [48164] (1)
          1. C-terminal domain of glutamyl-tRNA synthetase (GluRS) [48165]
            1. Thermus thermophilus [48166] (1) picpic
    59. R1 subunit of ribonucleotide reductase, N-terminal domain [48167] (1)
      1. R1 subunit of ribonucleotide reductase, N-terminal domain [48168] (1)
        1. R1 subunit of ribonucleotide reductase, N-terminal domain [48169] (1)
          1. R1 subunit of ribonucleotide reductase, N-terminal domain [48170]
            1. Escherichia coli [48171] (1) picpic
    60. Cryptochrome/photolyase FAD-binding domain [48172] (1)
      1. Cryptochrome/photolyase FAD-binding domain [48173] (1)
        1. Cryptochrome/photolyase FAD-binding domain [48174] (1)
          1. C-terminal domain of DNA photolyase [48175]
            1. Anacystis nidulans [48177] (1) picpic
    61. 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1)
      1. 6-phosphogluconate dehydrogenase C-terminal domain-like [48179] (3)
        1. Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain [48180] (1)
          1. 6-phosphogluconate dehydrogenase (6PGD) [48181]
            1. Sheep (Ovis orientalis aries) [48182] (5) picpic
        2. HCDH C-domain-like [48187] (1)
          1. Fatty oxidation complex alpha subunit, C-terminal domain [109949]
            1. Pseudomonas fragi [109950] (6) picpic
        3. N-(1-D-carboxylethyl)-L-norvaline dehydrogenase [48194] (1)
          1. N-(1-D-carboxylethyl)-L-norvaline dehydrogenase [48195]
            1. Arthrobacter, strain 1c [48196] (1) picpic
    62. Uteroglobin-like [48200] (1)
      1. Uteroglobin-like [48201] (1)
        1. Uteroglobin-like [48202] (2)
          1. Uteroglobin [48203]
            1. Rabbit (Oryctolagus cuniculus) [48204] (1) picpic
          2. Clara cell 17kDa protein [48205]
            1. Rat (Rattus norvegicus) [48206] (1) picpic
    63. alpha/alpha toroid [48207] (2)
      1. Six-hairpin glycosidases [48208] (2)
        1. Glucoamylase [48209] (2)
          1. Glucoamylase [48210]
            1. Aspergillus awamori, variant x100 [48211] (6) picpic
            2. Baker's yeast (Saccharomycopsis fibuligera) [48212] (1) picpic
        2. Cellulases catalytic domain [48213] (3)
          1. CelA cellulase [48214]
            1. Clostridium thermocellum [48215] (1) picpic
          2. CelD cellulase, C-terminal domain [48218]
            1. Clostridium thermocellum [48219] (1) picpic
          3. Processive endocellulase CelF (Cel48F) [48220]
            1. Clostridium cellulolyticum [48221] (1) picpic
      2. Terpenoid cyclases/Protein prenyltransferases [48239] (3)
        1. Terpenoid cyclase N-terminal domain [48240] (1)
          1. 5-Epi-aristolochene synthase [48241]
            1. Tobacco (Nicotiana tabacum) [48242] (3) picpic
        2. Terpene synthases [48243] (1)
          1. Squalene-hopene cyclase [48244]
            1. Alicyclobacillus acidocaldarius [48245] (2) picpic
        3. Complement components [48251] (1)
          1. C3D, a C3 fragment and ligand for complement receptor 2 [48252]
            1. Human (Homo sapiens) [48253] (1) picpic
    64. Citrate synthase [48255] (1)
      1. Citrate synthase [48256] (1)
        1. Citrate synthase [48257] (3)
          1. Citrate synthase [48258]
            1. Chicken (Gallus gallus) [48259] (12) picpic
            2. Pig (Sus scrofa) [48260] (2) picpic
            3. Antarctic bacterium DS2-3R [48262] (1) picpic
    65. Cytochrome P450 [48263] (1)
      1. Cytochrome P450 [48264] (1)
        1. Cytochrome P450 [48265] (4)
          1. Cytochrome P450-CAM [48266]
            1. Pseudomonas putida [48267] (22) picpic
          2. Cytochrome P450-NOR, nitric reductase [48270]
            1. Fungus (Fusarium oxysporum) [48271] (2) picpic
          3. Cytochrome P450-ERYF [48272]
            1. Saccaropolyspora erythraea [48273] (1) picpic
          4. Cytochrome P450-TERP [48274]
            1. Pseudomonas sp. [48275] (1) picpic
    66. Acid phosphatase/Vanadium-dependent haloperoxidase [48316] (1)
      1. Acid phosphatase/Vanadium-dependent haloperoxidase [48317] (1)
        1. Chloroperoxidase [48325] (1)
          1. Chloroperoxidase [48326]
            1. Curvularia inaequalis [48327] (7) picpic
    67. H-NS histone-like proteins [81274] (1)
      1. H-NS histone-like proteins [81273] (1)
        1. H-NS histone-like proteins [81272] (1)
          1. H1 protein (H-NS) [47733]
            1. Escherichia coli [47734] (2) picpic
    68. Sigma2 domain of RNA polymerase sigma factors [88945] (1)
      1. Sigma2 domain of RNA polymerase sigma factors [88946] (1)
        1. Sigma2 domain of RNA polymerase sigma factors [88947] (1)
          1. Sigma70 [88948]
            1. Escherichia coli [48332] (1) picpic
    69. GTPase activation domain, GAP [48349] (1)
      1. GTPase activation domain, GAP [48350] (2)
        1. BCR-homology GTPase activation domain (BH-domain) [48351] (1)
          1. p50 RhoGAP domain [48352]
            1. Human (Homo sapiens) [48353] (1) picpic
        2. p120GAP domain-like [48360] (1)
          1. p120GAP domain [48361]
            1. Human (Homo sapiens) [48362] (1) picpic
    70. alpha-alpha superhelix [48370] (4)
      1. ARM repeat [48371] (2)
        1. Armadillo repeat [48372] (1)
          1. beta-Catenin [48373]
            1. Mouse (Mus musculus) [48374] (2) picpic
        2. Leucine-rich repeat variant [48396] (1)
          1. Leucine-rich repeat variant [48397]
            1. Azotobacter vinelandii [48398] (1) picpic
      2. Sec7 domain [48425] (1)
        1. Sec7 domain [48426] (2)
          1. Exchange factor ARNO [48427]
            1. Human (Homo sapiens) [48428] (1) picpic
          2. Cytohesin-1/b2-1 [48429]
            1. Human (Homo sapiens) [48430] (1) picpic
      3. Bacterial muramidases [48435] (1)
        1. Bacterial muramidases [48436] (1)
          1. 70 KDa soluble lytic transglycosylase (SLT70), superhelical domain [48437]
            1. Escherichia coli [48438] (1) picpic
      4. TPR-like [48452] (1)
        1. Tetratricopeptide repeat (TPR) [48453] (1)
          1. Protein phosphatase 5 [48454]
            1. Human (Homo sapiens) [48455] (1) picpic
    71. Lipoxigenase [48483] (1)
      1. Lipoxigenase [48484] (2)
        1. Plant lipoxigenases [48485] (2)
          1. Lipoxigenase, C-terminal domain [48486]
            1. Soybean (Glycine max), isozyme L1 [48487] (1) picpic
            2. Soybean (Glycine max), isozyme L3 [48488] (4) picpic
        2. Animal lipoxigenases [48489] (1)
          1. 15-Lipoxygenase [48490]
            1. Rabbit (Oryctolagus cuniculus) [48491] (1) picpic
    72. Tetracyclin repressor-like, C-terminal domain [48497] (1)
      1. Tetracyclin repressor-like, C-terminal domain [48498] (1)
        1. Tetracyclin repressor-like, C-terminal domain [48499] (1)
          1. Tetracyclin repressor (Tet-repressor, TetR) [48500]
            1. Escherichia coli [48501] (6) picpic
    73. Nuclear receptor ligand-binding domain [48507] (1)
      1. Nuclear receptor ligand-binding domain [48508] (1)
        1. Nuclear receptor ligand-binding domain [48509] (2)
          1. Retinoid-X receptor alpha (RXR-alpha) [48510]
            1. Human (Homo sapiens) [48511] (1) picpic
          2. Retinoic acid receptor gamma (RAR-gamma) [48515]
            1. Human (Homo sapiens) [48516] (3) picpic
    74. Phospholipase C/P1 nuclease [48536] (1)
      1. Phospholipase C/P1 nuclease [48537] (2)
        1. Phospholipase C [48538] (2)
          1. Bacterial phosholipase C [48539]
            1. Bacillus cereus [48540] (1) picpic
          2. Alpha-toxin, N-terminal domain [48541]
            1. Clostridium perfringens, different strains [48542] (1) picpic
        2. P1 nuclease [48543] (1)
          1. P1 nuclease [48544]
            1. Penicillium citrinum [48545] (1) picpic
    75. Serum albumin-like [48551] (1)
      1. Serum albumin-like [48552] (1)
        1. Serum albumin-like [48553] (1)
          1. Serum albumin [48554]
            1. Human (Homo sapiens) [48555] (9) picpic
    76. L-aspartase-like [48556] (1)
      1. L-aspartase-like [48557] (1)
        1. L-aspartase/fumarase [48558] (1)
          1. Fumarase [48561]
            1. Baker's yeast (Saccharomyces cerevisiae) [48563] (1) picpic
    77. Terpenoid synthases [48575] (1)
      1. Terpenoid synthases [48576] (2)
        1. Isoprenyl diphosphate synthases [48577] (1)
          1. Farnesyl diphosphate synthase (geranyltranstransferase) [48578]
            1. Chicken (Gallus gallus) [48579] (5) picpic
        2. Terpenoid cyclase C-terminal domain [48583] (1)
          1. 5-Epi-aristolochene synthase [48584]
            1. Tobacco (Nicotiana tabacum) [48585] (3) picpic
    78. GroEL equatorial domain-like [48591] (1)
      1. GroEL equatorial domain-like [48592] (1)
        1. GroEL chaperone, ATPase domain [48593] (1)
          1. GroEL, E domain [48594]
            1. Escherichia coli [48595] (1) picpic
    79. Cysteine alpha-hairpin motif [47071] (1)
      1. Cysteine alpha-hairpin motif [47072] (1)
        1. p8-MTCP1 [47073] (1)
          1. p8-MTCP1 [47074]
            1. Human (Homo sapiens) [47075] (2) picpic
    80. Phospholipase A2, PLA2 [48618] (1)
      1. Phospholipase A2, PLA2 [48619] (2)
        1. Vertebrate phospholipase A2 [48623] (10)
          1. Snake phospholipase A2 [48624]
            1. Taiwan cobra (Naja naja atra) [48625] (1) picpic
            2. Indian cobra (Naja naja naja) [48626] (1) picpic
            3. Chinese water moccasin (Agkistrodon halys pallas), different isoforms [48628] (2) picpic
            4. Eastern cottonmouth snake (Agkistridon piscivorus) [48629] (1) picpic
            5. Mainland tiger snake (Notechis scutatus scutatus), notexin [48631] (1) picpic
            6. Russell's viper (Vipera russelli) [48634] (1) picpic
            7. Sand viper (Vipera ammodytes meridionalis), vipoxin inhibitor [88517] (1) picpic
          2. Phospholipase A2 [48637]
            1. Human (Homo sapiens), synovial fluid [48638] (2) picpic
            2. Cow (Bos taurus), pancreas [48639] (17) picpic
            3. Pig (Sus scrofa), pancreas [48640] (6) picpic
        2. Insect phospholipase A2 [48620] (1)
          1. Phospholipase A2 [48621]
            1. European honeybee (Apis mellifera) [48622] (1) picpic
    81. Fungal elicitin [48646] (1)
      1. Fungal elicitin [48647] (1)
        1. Fungal elicitin [48648] (1)
          1. beta-cryptogein [48649]
            1. Phytophthora cryptogea [48650] (3) picpic
    82. Multiheme cytochromes [48694] (1)
      1. Multiheme cytochromes [48695] (2)
        1. Cytochrome c3-like [48696] (5)
          1. Cytochrome c3 [48697]
            1. Desulfovibrio desulfuricans, different strains [48698] (3) picpic
            2. Desulfovibrio vulgaris [48699] (3) picpic
            3. Desulfovibrio gigas [48700] (1) picpic
            4. Desulfomicrobium norvegicum [48702] (1) picpic
          2. Cytochrome c7 (cytochrome c551.5, PpcA) [48703]
            1. Desulfuromonas acetoxidans [48704] (2) picpic
        2. Di-heme elbow motif [48711] (1)
          1. Cytochrome c554 [48714]
            1. Nitrosomonas europaea [48715] (1) picpic
  2. All beta proteins [48724] (62)
    1. Immunoglobulin-like beta-sandwich [48725] (8)
      1. Immunoglobulin [48726] (4)
        1. V set domains (antibody variable domain-like) [48727] (17)
          1. Immunoglobulin light chain kappa variable domain, VL-kappa [88519]
            1. Human (Homo sapiens), cluster 1 [88520] (1) picpic
            2. Human (Homo sapiens), cluster 2 [88521] (3) picpic
            3. Mouse (Mus musculus), cluster 1.1 [88524] (2) picpic
            4. Mouse (Mus musculus), cluster 1.2 [88525] (1) picpic
            5. Engineered (including hybrid species) [88533] (1) picpic
          2. Immunoglobulin light chain lambda variable domain, VL-lambda [88534]
            1. Human (Homo sapiens), cluster 2 [88536] (2) picpic
            2. Mouse (Mus musculus) [88541] (1) picpic
          3. Immunoglobulin heavy chain variable domain, VH [88543]
            1. Mouse (Mus musculus), cluster 3.2 [88552] (1) picpic
            2. Engineered (including hybrid species) [88562] (1) picpic
          4. Camelid IG heavy chain variable domain, VHh [88563]
            1. Llama (Lama glama) [88565] (1) picpic
          5. T-cell antigen receptor [48933]
            1. Mouse (Mus musculus), beta-chain [48936] (1) picpic
          6. Immunoreceptor CTLA-4 (CD152), N-terminal fragment [48939]
            1. Human (Homo sapiens) [48940] (1) picpic
          7. Myelin membrane adhesion molecule P0 [48728]
            1. Rat (Rattus norvegicus) [48729] (1) picpic
          8. CD8 [48734]
            1. Human (Homo sapiens) [48735] (1) picpic
          9. CD4 V-set domains [48737]
            1. Human (Homo sapiens) [48738] (6) picpic
            2. Rat (Rattus rattus) [48739] (1) picpic
          10. CD2, first domain [48740]
            1. Human (Homo sapiens) [48741] (3) picpic
        2. C1 set domains (antibody constant domain-like) [48942] (5)
          1. Immunoglobulin light chain kappa constant domain, CL-kappa [88566]
            1. Mouse (Mus musculus) [88567] (1) picpic
            2. Human (Homo sapiens) [88569] (17) picpic
          2. Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma [88589]
            1. Guinea pig (Cavia porcellus) [49123] (1) picpic
          3. T-cell antigen receptor [49125]
            1. Mouse (Mus musculus), beta-chain [49128] (1) picpic
          4. beta2-microglobulin [88600]
            1. Cow (Bos taurus) [48946] (1) picpic
        3. C2 set domains [49142] (5)
          1. Intercellular cell adhesion molecule-1 (ICAM-1) [49145]
            1. Human (Homo sapiens) [49146] (1) picpic
          2. Intercellular cell adhesion molecule-2 (ICAM-2) [49147]
            1. Human (Homo sapiens) [49148] (1) picpic
          3. CD4 C2-set domains [49149]
            1. Human (Homo sapiens) [49150] (6) picpic
            2. Rat (Rattus rattus) [49151] (1) picpic
          4. CD2, second domain [49152]
            1. Human (Homo sapiens) [49153] (1) picpic
        4. I set domains [49159] (9)
          1. Intercellular adhesion molecule-1, ICAM-1 [49162]
            1. Human (Homo sapiens) [49163] (1) picpic
          2. Intercellular adhesion molecule-2, ICAM-2 [49164]
            1. Human (Homo sapiens) [49165] (1) picpic
          3. Neural cell adhesion molecule (NCAM) [49166]
            1. Rat (Rattus norvegicus) [49167] (1) picpic
          4. Telokin [49170]
            1. Turkey (Meleagris gallopavo) [49171] (1) picpic
          5. Titin [49172]
            1. Human (Homo sapiens), different modules [49173] (4) picpic
          6. Twitchin [49174]
            1. Nematode (Caenorhabditis elegans) [49175] (3) picpic
            2. Human (Homo sapiens), Ig repeat 27 [49176] (2) picpic
          7. Killer cell inhibitory receptor [49202]
            1. Human (Homo sapiens), kir2dl3 [49203] (2) picpic
            2. Human (Homo sapiens), p58-cl42 kir [49204] (2) picpic
      2. E set domains [81296] (7)
        1. NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain [81279] (1)
          1. p50 subunit of NF-kappa B transcription factor [49248]
            1. Mouse (Mus musculus) [49250] (1) picpic
        2. E-set domains of sugar-utilizing enzymes [81282] (9)
          1. Galactose oxidase, C-terminal domain [49209]
            1. Dactylium dendroides [49210] (3) picpic
          2. Sialidase, "linker" domain [49237]
            1. Micromonospora viridifaciens [49238] (2) picpic
          3. CelD cellulase, N-terminal domain [49231]
            1. Clostridium thermocellum [49232] (1) picpic
          4. Bacterial chitobiase (N-acetyl-beta-glucoseaminidase), C-terminal domain [49211]
            1. Serratia marcescens [49212] (2) picpic
          5. Cyclomaltodextrin glycanotransferase, domain D [49215]
            1. Bacillus circulans, different strains [49216] (18) picpic
            2. Bacillus stearothermophilus [49217] (1) picpic
            3. Thermoanaerobacterium thermosulfurigenes, EM1 [49220] (2) picpic
          6. Isoamylase, N-terminal domain N [49226]
            1. Pseudomonas amyloderamosa [49227] (1) picpic
          7. Chitinase A, N-terminal domain N [49233]
            1. Serratia marcescens [49234] (1) picpic
        3. Arthropod hemocyanin, C-terminal domain [81283] (2)
          1. Arthropod hemocyanin, C-terminal domain [49228]
            1. Horseshoe crab (Limulus polyphemus) [49229] (4) picpic
            2. Spiny lobster (Panulirus interruptus) [49230] (7) picpic
        4. Class II viral fusion proteins C-terminal domain [81284] (1)
          1. Envelope glycoprotein [49213]
            1. Tick-borne encephalitis virus [49214] (1) picpic
        5. ML domain [81287] (2)
          1. Major mite allergen [49256]
            1. House-dust mite (Dermatophagoides farinae), Der f 2 [49257] (2) picpic
            2. House-dust mite (Dermatophagoides pteronyssinus), Der p 2 [49258] (1) picpic
        6. RhoGDI-like [81288] (1)
          1. Rho GDP-dissociation inhibitor 1, RhoGDI [49241]
            1. Cow (Bos taurus) [49243] (2) picpic
        7. Filamin repeat (rod domain) [81290] (1)
          1. F-actin cross-linking gelation factor (ABP-120) repeats [49239]
            1. Slime mold (Dictyostelium discoideum) [49240] (1) picpic
      3. Fibronectin type III [49265] (1)
        1. Fibronectin type III [49266] (8)
          1. Extracellular region of human tissue factor [49267]
            1. Human (Homo sapiens) [49268] (4) picpic
          2. Fibronectin, different Fn3 modules [49270]
            1. Human (Homo sapiens) [49271] (7) picpic
            2. Mouse (Mus musculus) [49272] (4) picpic
          3. Tenascin [49273]
            1. Human (Homo sapiens) [49275] (1) picpic
          4. Neuroglian, two amino proximal Fn3 repeats [49276]
            1. Drosophila melanogaster [49277] (2) picpic
          5. Granulocyte colony-stimulating factor (GC-SF) receptor [49291]
            1. Mouse (Mus musculus) [49292] (2) picpic
          6. Cytokine receptor gp130 cytokine-binding domains [49295]
            1. Human (Homo sapiens) [49296] (1) picpic
          7. Type I titin module [49297]
            1. Human (Homo sapiens) [49298] (1) picpic
      4. Cadherin-like [49313] (1)
        1. Cadherin [49314] (2)
          1. N-cadherin (neural) [49315]
            1. Mouse (Mus musculus) [49316] (1) picpic
          2. E-cadherin (epithelial) [49317]
            1. Mouse (Mus musculus) [49318] (1) picpic
      5. Actinoxanthin-like [49319] (1)
        1. Actinoxanthin-like [49320] (4)
          1. Macromycin [49321]
            1. Streptomyces macromomyceticus [49322] (1) picpic
          2. Neocarzinostatin [49323]
            1. Streptomyces carzinostaticus [49324] (1) picpic
          3. Actinoxanthin [49325]
            1. Actinomyces globisporus, number 1131 [49326] (1) picpic
          4. Kedarcidin [49327]
            1. Actimomycete, strain L585-6 [49328] (1) picpic
      6. Cu,Zn superoxide dismutase-like [49329] (1)
        1. Cu,Zn superoxide dismutase-like [49330] (3)
          1. Cu,Zn superoxide dismutase, SOD [49331]
            1. Human (Homo sapiens) [49333] (1) picpic
            2. Baker's yeast (Saccharomyces cerevisiae) [49336] (3) picpic
            3. Escherichia coli [49338] (1) picpic
      7. PapD-like [49354] (1)
        1. Pilus chaperone [49355] (2)
          1. Pilus chaperone PapD, N-domain [49356]
            1. Escherichia coli [49357] (1) picpic
          2. Periplasmic chaperone FimC [49358]
            1. Escherichia coli [49359] (1) picpic
      8. Superoxide reductase-like [49367] (1)
        1. Superoxide reductase-like [49368] (1)
          1. Desulfoferrodoxin C-terminal domain [49371]
            1. Desulfovibrio desulfuricans [49372] (1) picpic
    2. Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (5)
      1. Diphtheria toxin, C-terminal domain [49380] (1)
        1. Diphtheria toxin, C-terminal domain [49381] (1)
          1. Diphtheria toxin, C-terminal domain [49382]
            1. Corynebacterium diphtheriae [49383] (2) picpic
      2. Carbohydrate-binding domain [49384] (3)
        1. Cellulose-binding domain family II [49385] (2)
          1. Exo-1,4-beta-D-glycanase (cellulase, xylanase), cellulose-binding domain, CBD [49386]
            1. Cellulomonas fimi [49387] (2) picpic
          2. Endo-1,4-beta xylanase D, xylan binding domain, XBD [49388]
            1. Cellulomonas fimi [49389] (2) picpic
        2. Cellulose-binding domain family III [49390] (1)
          1. Cohesin domain [49396]
            1. Clostridium thermocellum, cellulosome, various modules [49397] (1) picpic
        3. Bacterial chitobiase, n-terminal domain [49398] (1)
          1. Bacterial chitobiase, n-terminal domain [49399]
            1. Serratia marcescens [49400] (2) picpic
      3. Bacterial adhesins [49401] (1)
        1. Collagen-binding domain of adhesin [49402] (1)
          1. Collagen-binding domain of adhesin [49403]
            1. Staphylococcus aureus [49404] (1) picpic
      4. p53-like transcription factors [49417] (1)
        1. Rel/Dorsal transcription factors, DNA-binding domain [81315] (1)
          1. T-cell transcription factor NFAT1 (NFATC), DNA-binding domain [49421]
            1. Human (Homo sapiens) [49422] (1) picpic
      5. Cytochrome f, large domain [49441] (1)
        1. Cytochrome f, large domain [49442] (1)
          1. Cytochrome f, large domain [49443]
            1. Turnip (Brassica rapa) [49444] (2) picpic
    3. Prealbumin-like [49451] (1)
      1. Starch-binding domain-like [49452] (1)
        1. Starch-binding domain [49453] (4)
          1. Cyclodextrin glycosyltransferase, C-terminal domain [49454]
            1. Bacillus circulans, different strains [49455] (18) picpic
            2. Bacillus stearothermophilus [49456] (1) picpic
            3. Thermoanaerobacterium thermosulfurigenes, EM1 [49459] (2) picpic
          2. Glucoamylase, granular starch-binding domain [49460]
            1. Aspergillus niger [49461] (4) picpic
    4. alpha-Amylase inhibitor tendamistat [49497] (1)
      1. alpha-Amylase inhibitor tendamistat [49498] (1)
        1. alpha-Amylase inhibitor tendamistat [49499] (1)
          1. alpha-Amylase inhibitor tendamistat [49500]
            1. Streptomyces tendae [49501] (4) picpic
    5. Cupredoxin-like [49502] (1)
      1. Cupredoxins [49503] (3)
        1. Plastocyanin/azurin-like [49504] (19)
          1. Amicyanin [49505]
            1. Paracoccus denitrificans [49506] (3) picpic
          2. Plastocyanin [49507]
            1. Poplar (Populus nigra), variant italica [49508] (8) picpic
            2. French bean (Phaseolus vulgaris) [49509] (1) picpic
            3. Parsley (Petroselinum crispum) [49510] (2) picpic
            4. Spinach (Spinacia oleracea) [49511] (1) picpic
            5. Sea lettuce (Ulva pertusa) [49513] (1) picpic
            6. Green alga (Chlamydomonas reinhardtii) [49514] (1) picpic
            7. Green alga (Enteromorpha prolifera) [49515] (1) picpic
            8. Fern (Adiantum capillus-veneris) [49516] (2) picpic
            9. Anabaena variabilis [49517] (1) picpic
            10. Cyanobacterium (Synechocystis sp.), pcc 6803 [49519] (1) picpic
          3. Pseudoazurin [49522]
            1. Alcaligenes faecalis, strain s-6 [49523] (10) picpic
            2. Methylobacterium extorquens, strain am1 [49524] (1) picpic
            3. Achromobacter cycloclastes [49525] (4) picpic
          4. Plantacyanin [49527]
            1. Cucumber (Cucumis sativus) [49528] (1) picpic
          5. Azurin [49530]
            1. Pseudomonas aeruginosa [49533] (1) picpic
            2. Pseudomonas fluorescens [49534] (1) picpic
          6. Rusticyanin [49537]
            1. Thiobacillus ferrooxidans [49538] (4) picpic
          7. Stellacyanin [49539]
            1. Cucumber (Cucumis sativus) [49540] (1) picpic
        2. Periplasmic domain of cytochrome c oxidase subunit II [49541] (1)
          1. Quinol oxidase (CyoA) [49542]
            1. Escherichia coli [49543] (2) picpic
        3. Multidomain cupredoxins [49550] (4)
          1. Nitrite reductase, NIR [49551]
            1. Achromobacter cycloclastes [49552] (10) picpic
            2. Alcaligenes faecalis, strain s-6 [49553] (2) picpic
            3. Alcaligenes xylosoxidans [49554] (2) picpic
          2. Ceruloplasmin [49559]
            1. Human (Homo sapiens) [49560] (6) picpic
    6. C2 domain-like [49561] (3)
      1. C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (2)
        1. PLC-like (P variant) [49563] (1)
          1. Domain from cytosolic phospholipase A2 [49566]
            1. Human (Homo sapiens) [49567] (2) picpic
        2. Synaptotagmin-like (S variant) [49575] (1)
          1. Synaptogamin I [49576]
            1. Rat (Rattus norvegicus) [49577] (1) picpic
      2. Periplasmic chaperone C-domain [49584] (1)
        1. Periplasmic chaperone C-domain [49585] (2)
          1. PapD [49586]
            1. Escherichia coli [49587] (1) picpic
          2. FimC [49588]
            1. Escherichia coli [49589] (1) picpic
      3. PHL pollen allergen [49590] (1)
        1. PHL pollen allergen [49591] (1)
          1. PHL P 2 [49592]
            1. Timothy grass (Phleum pratense) [49593] (3) picpic
    7. Nucleoplasmin-like/VP (viral coat and capsid proteins) [88632] (2)
      1. ssDNA viruses [88645] (3)
        1. Microviridae-like VP [49612] (1)
          1. Microvirus capsid proteins [49613]
            1. Bacteriophage phi-X174 [49614] (1) picpic
        2. Parvoviridae-like VP [88646] (2)
          1. Parvovirus (panleukopenia virus) capsid protein [49661]
            1. Feline panleukopenia virus, strain b [49689] (1) picpic
            2. Canine parvovirus [49662] (1) picpic
        3. Densovirinae-like VP [88647] (1)
          1. Densovirus capsid protein [49652]
            1. Galleria mellonella densovirus [49653] (1) picpic
      2. PHM/PNGase F [49742] (2)
        1. Glycosyl-asparaginase [49743] (1)
          1. Peptide:N-glycosidase F, PNGase F [49744]
            1. Flavobacterium meningosepticum [49745] (6) picpic
        2. Peptidylglycine alpha-hydroxylating monooxygenase, PHM [49746] (1)
          1. Peptidylglycine alpha-hydroxylating monooxygenase, PHM [63402]
            1. Rat (Rattus norvegicus) [49748] (2) picpic
    8. gamma-Crystallin-like [49694] (1)
      1. gamma-Crystallin-like [49695] (3)
        1. Crystallins/Ca-binding development proteins [49696] (5)
          1. gamma-Crystallin [49697]
            1. Cow (Bos taurus), isoform II (B) [49698] (7) picpic
            2. Cow (Bos taurus), isoform F [49701] (2) picpic
          2. beta-Crystallin [49702]
            1. Cow (Bos taurus) [49703] (2) picpic
          3. Protein S [49706]
            1. Myxococcus xanthus [49707] (4) picpic
          4. Spherulin 3a (S3a) [49708]
            1. Slime mold (Physarum polycephalum) [49709] (1) picpic
        2. Yeast killer toxin [49710] (1)
          1. Yeast killer toxin [49711]
            1. Williopsis mrakii [49712] (1) picpic
        3. Streptomyces metalloproteinase inhibitor, SMPI [49713] (1)
          1. Streptomyces metalloproteinase inhibitor, SMPI [49714]
            1. Streptomyces nigrescens [49715] (1) picpic
    9. Lipase/lipooxygenase domain (PLAT/LH2 domain) [49722] (1)
      1. Lipase/lipooxygenase domain (PLAT/LH2 domain) [49723] (3)
        1. Lipoxigenase N-terminal domain [49724] (3)
          1. Plant lipoxigenase [49725]
            1. Soybean (Glycine max), isozyme L1 [49726] (1) picpic
            2. Soybean (Glycine max), isozyme L3 [49727] (4) picpic
          2. 15-Lipoxygenase [49728]
            1. Rabbit (Oryctolagus cuniculus) [49729] (1) picpic
        2. Colipase-binding domain [49730] (2)
          1. Pancreatic lipase, C-terminal domain [49731]
            1. Guinea pig (Cavia porcellus) [49735] (1) picpic
            2. Dog (Canis familiaris) [49736] (1) picpic
        3. Alpha-toxin, C-terminal domain [49738] (1)
          1. Alpha-toxin, C-terminal domain [49739]
            1. Clostridium perfringens, different strains [49740] (1) picpic
    10. Heat shock protein 70kD (HSP70), peptide-binding domain [100919] (1)
      1. Heat shock protein 70kD (HSP70), peptide-binding domain [100920] (1)
        1. Heat shock protein 70kD (HSP70), peptide-binding domain [100921] (1)
          1. DnaK [100922]
            1. Escherichia coli [100923] (2) picpic
    11. Ecotin, trypsin inhibitor [49771] (1)
      1. Ecotin, trypsin inhibitor [49772] (1)
        1. Ecotin, trypsin inhibitor [49773] (1)
          1. Ecotin, trypsin inhibitor [49774]
            1. Escherichia coli [49775] (1) picpic
    12. PEBP-like [49776] (1)
      1. PEBP-like [49777] (1)
        1. Phosphatidylethanolamine binding protein [49778] (1)
          1. Phosphatidylethanolamine binding protein, PEBP [49779]
            1. Cow (Bos taurus) [49781] (1) picpic
    13. Galactose-binding domain-like [49784] (1)
      1. Galactose-binding domain-like [49785] (3)
        1. Galactose-binding domain [49786] (2)
          1. Galactose oxidase, N-terminal domain [49787]
            1. Dactylium dendroides [49788] (3) picpic
          2. Sialidase, C-terminal domain [49789]
            1. Micromonospora viridifaciens [49790] (2) picpic
        2. delta-Endotoxin, C-terminal domain [49796] (2)
          1. delta-Endotoxin, C-terminal domain [49797]
            1. Bacillus thuringiensis tenebrionis, CRYIIIA (BT13) [49798] (1) picpic
            2. Bacillus thuringiensis, CRYIA (A) [49799] (1) picpic
        3. CBM4/9 [74893] (1)
          1. Cellulose-binding domain of cellulase C [49809]
            1. Cellulomonas fimi [49810] (2) picpic
    14. ENV polyprotein, receptor-binding domain [49829] (1)
      1. ENV polyprotein, receptor-binding domain [49830] (1)
        1. ENV polyprotein, receptor-binding domain [49831] (1)
          1. F-MuLV receptor-binding domain [49832]
            1. Friend murine leukemia virus [49833] (1) picpic
    15. Virus attachment protein globular domain [49834] (1)
      1. Virus attachment protein globular domain [49835] (1)
        1. Adenovirus fiber protein "knob" domain [49836] (1)
          1. Adenovirus fiber protein "knob" domain [49837]
            1. Human adenovirus type 5 [49838] (1) picpic
    16. TNF-like [49841] (1)
      1. TNF-like [49842] (1)
        1. TNF-like [49843] (1)
          1. Extracellular domain of CD40 ligand [49844]
            1. Human (Homo sapiens) [49845] (1) picpic
    17. CUB-like [49853] (1)
      1. Spermadhesin, CUB domain [49854] (1)
        1. Spermadhesin, CUB domain [49855] (1)
          1. Acidic seminal fluid protein (ASFP) [49856]
            1. Cow (Bos taurus) [49857] (1) picpic
    18. Osmotin, thaumatin-like protein [49869] (1)
      1. Osmotin, thaumatin-like protein [49870] (1)
        1. Osmotin, thaumatin-like protein [49871] (2)
          1. Pathogenesis-related protein 5d [49872]
            1. Common tobacco (Nicotiana tabacum) [49873] (1) picpic
          2. Thaumatin [49876]
            1. Ketemfe (Thaumatococcus daniellii) [49877] (4) picpic
    19. SMAD/FHA domain [49878] (1)
      1. SMAD/FHA domain [49879] (1)
        1. SMAD domain [49880] (1)
          1. Smad4 tumor suppressor C-terminal domain [49881]
            1. Human (Homo sapiens) [49882] (1) picpic
    20. Concanavalin A-like lectins/glucanases [49898] (1)
      1. Concanavalin A-like lectins/glucanases [49899] (8)
        1. Legume lectins [49900] (5)
          1. Concanavalin A [49901]
            1. Jack bean (Canavalia ensiformis) [49902] (8) picpic
          2. Legume lectin [49904]
            1. West-central african legume (Griffonia simplicifolia) [49907] (3) picpic
            2. Coral tree (Erythrina corallodendron) [49908] (6) picpic
            3. Soybean (Glycine max) [49913] (3) picpic
            4. Horse gram (Dolichos biflorus), different isoforms [49915] (1) picpic
        2. Glycosyl hydrolases family 16 [49925] (3)
          1. Bacillus 1-3,1-4-beta-glucanase [49926]
            1. Bacillus licheniformis [49927] (1) picpic
            2. Hybrid protein: residues 1-16 from Bacillus amyloliquefaciens and Bacillus macerans [49928] (3) picpic
            3. Bacillus macerans [49929] (2) picpic
        3. Galectin (animal S-lectin) [49932] (2)
          1. Charcot-Leyden crystal (CLC) protein [49938]
            1. Human (Homo sapiens) [49939] (1) picpic
          2. Galectin-3 CRD [49940]
            1. Human (Homo sapiens) [49941] (1) picpic
        4. Clostridium neurotoxins, the second last domain [49956] (1)
          1. Tetanus neurotoxin [49957]
            1. Clostridium tetani [49958] (2) picpic
        5. Vibrio cholerae sialidase, N-terminal and insertion domains [49965] (1)
          1. Vibrio cholerae sialidase, N-terminal and insertion domains [49966]
            1. Vibrio cholerae [49967] (2) picpic
        6. Leech intramolecular trans-sialidase, N-terminal domain [49968] (1)
          1. Leech intramolecular trans-sialidase, N-terminal domain [49969]
            1. North american leech (Macrobdella decora) [49970] (5) picpic
        7. Glycosyl hydrolase family 7 catalytic core [49971] (2)
          1. Cellobiohydrolase I (cellulase, Endoglucanase I, CBH1) [68900]
            1. Trichoderma reesei, Cel7A [68898] (4) picpic
            2. Humicola insolens, Cel7b [49977] (1) picpic
        8. Xylanase/endoglucanase 11/12 [49978] (6)
          1. Xylanase II [49979]
            1. Bacillus circulans [49980] (4) picpic
            2. Trichoderma harzianum [49983] (1) picpic
            3. Trichoderma reesei, xynI [49984] (1) picpic
            4. Thermomyces lanuginosus [49986] (1) picpic
            5. Aspergillus kawachii [49988] (1) picpic
          2. Family 12 endo-1,4-beta-glucanase (cellulase) catalytic domain [49991]
            1. Streptomyces lividans, CelB2 [49992] (1) picpic
    21. Supersandwich [49993] (1)
      1. Amine oxidase catalytic domain [49998] (1)
        1. Amine oxidase catalytic domain [49999] (1)
          1. Copper amine oxidase, domain 3 [50000]
            1. Arthrobacter globiformis [50003] (3) picpic
    22. ISP domain [50021] (1)
      1. ISP domain [50022] (1)
        1. Rieske iron-sulfur protein (ISP) [50023] (2)
          1. ISP subunit of the mitochondrial cytochrome bc1-complex, water-soluble domain [50024]
            1. Cow (Bos taurus) [50025] (1) picpic
          2. ISP subunit from chloroplast cytochrome bf complex [50027]
            1. Spinach (Spinacia oleracea) [50028] (1) picpic
    23. SH3-like barrel [50036] (7)
      1. C-terminal domain of transcriptional repressors [50037] (2)
        1. Biotin repressor (BirA) [50038] (1)
          1. Biotin repressor/biotin holoenzyme synthetase, C-terminal domain [50039]
            1. Escherichia coli [50040] (2) picpic
        2. Iron-dependent regulator [50041] (1)
          1. Diphtheria toxin repressor (DtxR) [50042]
            1. Corynebacterium diphtheriae [50043] (3) picpic
      2. SH3-domain [50044] (1)
        1. SH3-domain [50045] (15)
          1. Fyn proto-oncogene tyrosine kinase, SH3 domain [50048]
            1. Human (Homo sapiens) [50049] (2) picpic
          2. SH3 domain from nebulin [50050]
            1. Human (Homo sapiens) [50051] (2) picpic
          3. Abl tyrosine kinase, SH3 domain [50052]
            1. Mouse (Mus musculus) [50053] (1) picpic
            2. Human (Homo sapiens) [50054] (2) picpic
          4. Phosphatidylinositol 3-kinase (p85-alpha subunit, pi3k), SH3 domain [50055]
            1. Human (Homo sapiens) [50056] (3) picpic
            2. Cow (Bos taurus) [50057] (2) picpic
          5. alpha-Spectrin, SH3 domain [50058]
            1. Chicken (Gallus gallus) [50059] (6) picpic
          6. IL-2 inducible T-cell (Itc) kinase [50060]
            1. Mouse (Mus musculus) [50061] (1) picpic
          7. Hemapoetic cell kinase Hck [50062]
            1. Human (Homo sapiens) [50063] (2) picpic
          8. c-src protein tyrosine kinase [50064]
            1. Human (Homo sapiens) [50065] (2) picpic
            2. Chicken (Gallus gallus) [50066] (3) picpic
          9. Bruton's tyrosine kinase [50068]
            1. Human (Homo sapiens) [50069] (2) picpic
          10. Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains [50070]
            1. Human (Homo sapiens) [50071] (2) picpic
          11. Phospholipase C, SH3 domain [50074]
            1. Human (Homo sapiens) [50075] (2) picpic
          12. Amphiphysin 2 [50080]
            1. Rat (Rattus norvegicus) [50081] (1) picpic
      3. Myosin S1 fragment, N-terminal domain [50084] (1)
        1. Myosin S1 fragment, N-terminal domain [50085] (1)
          1. Myosin S1 fragment, N-terminal domain [50086]
            1. Slime mold (Dictyostelium discoideum) [50089] (8) picpic
      4. Chromo domain-like [54160] (2)
        1. "Histone-like" proteins from archaea [54161] (2)
          1. DNA-binding protein [54162]
            1. Archaeon Sulfolobus solfataricus, Sso7d [54163] (3) picpic
            2. Archaeon Sulfolobus acidocaldarius, Sac7d [54164] (1) picpic
        2. Chromo domain [54165] (1)
          1. Heterochromatin protein 1, HP1 [54166]
            1. Mouse (Mus musculus), HP1 beta (MOD1, M31) [54167] (1) picpic
      5. Electron transport accessory proteins [50090] (2)
        1. R67 dihydrofolate reductase [50091] (1)
          1. R67 dihydrofolate reductase [50092]
            1. Escherichia coli, plasmid PLZ1 [50093] (2) picpic
        2. Photosystem I accessory protein E (PsaE) [50094] (1)
          1. Photosystem I accessory protein E (PsaE) [50095]
            1. Cyanobacterium (Synechococcus sp.), pcc 7002 [50096] (2) picpic
      6. Translation proteins SH3-like domain [50104] (1)
        1. eIF5a N-terminal domain-like [50110] (2)
          1. Eukaryotic initiation translation factor 5a (eIF5a) [50111]
            1. Archaeon Methanococcus jannaschii [50112] (1) picpic
            2. Archaeon Pyrobaculum aerophilum [50113] (1) picpic
      7. Cell growth inhibitor/plasmid maintenance toxic component [50118] (1)
        1. CcdB [50119] (1)
          1. CcdB [50120]
            1. Escherichia coli [50121] (2) picpic
    24. GroES-like [50128] (1)
      1. GroES-like [50129] (1)
        1. Alcohol dehydrogenase-like, N-terminal domain [50136] (2)
          1. Alcohol dehydrogenase [50137]
            1. Horse (Equus caballus) [50138] (6) picpic
          2. Hypothetical protein YhdH [101706]
            1. Escherichia coli [101707] (3) picpic
    25. PDZ domain-like [50155] (1)
      1. PDZ domain-like [50156] (2)
        1. PDZ domain [50157] (1)
          1. Discs large protein homolog [50158]
            1. Human (Homo sapiens) [50159] (1) picpic
        2. Interleukin 16 [50172] (1)
          1. Interleukin 16 [50173]
            1. Human (Homo sapiens) [50174] (1) picpic
    26. N-terminal domains of the minor coat protein g3p [50175] (1)
      1. N-terminal domains of the minor coat protein g3p [50176] (1)
        1. N-terminal domains of the minor coat protein g3p [50177] (2)
          1. N-terminal domains of the minor coat protein g3p [50178]
            1. Bacteriophage M13 [50179] (2) picpic
            2. Bacteriophage fd [50180] (1) picpic
    27. Ribosomal protein L14 [50192] (1)
      1. Ribosomal protein L14 [50193] (1)
        1. Ribosomal protein L14 [50194] (1)
          1. Ribosomal protein L14 [50195]
            1. Bacillus stearothermophilus [50196] (1) picpic
    28. OB-fold [50198] (5)
      1. Staphylococcal nuclease [50199] (1)
        1. Staphylococcal nuclease [50200] (1)
          1. Staphylococcal nuclease [50201]
            1. Staphylococcus aureus [50202] (38) picpic
      2. Bacterial enterotoxins [50203] (2)
        1. Bacterial AB5 toxins, B-subunits [50204] (1)
          1. Verotoxin-1/shiga-toxin, B-pentamer [50210]
            1. Escherichia coli [50211] (1) picpic
        2. Superantigen toxins, N-terminal domain [50219] (5)
          1. Staphylococcal enterotoxin C2, SEC2 [50222]
            1. Staphylococcus aureus [50223] (2) picpic
          2. Toxic shock syndrome toxin-1 (TSST-1) [50224]
            1. Staphylococcus aureus [50225] (2) picpic
          3. Staphylococcal enterotoxin B, SEB [50226]
            1. Staphylococcus aureus [50227] (3) picpic
          4. Streptococcal superantigen Spe-C [50232]
            1. Streptococcus pyogenes [50233] (1) picpic
          5. Streptococcal superantigen Smez-2 [50236]
            1. Streptococcus pyogenes [50237] (1) picpic
      3. TIMP-like [50242] (1)
        1. Tissue inhibitor of metalloproteinases, TIMP [50243] (1)
          1. TIMP-2 [50246]
            1. Human (Homo sapiens) [50247] (2) picpic
      4. Nucleic acid-binding proteins [50249] (6)
        1. Anticodon-binding domain [50250] (1)
          1. Lysyl-tRNA synthetase (LysRS) [50256]
            1. Escherichia coli, gene lysS [50257] (2) picpic
        2. DNA helicase RuvA subunit, N-terminal domain [50259] (1)
          1. DNA helicase RuvA subunit, N-terminal domain [50260]
            1. Escherichia coli [50261] (2) picpic
        3. Cold shock DNA-binding domain-like [50282] (8)
          1. Major cold shock protein [50283]
            1. Escherichia coli [50284] (1) picpic
            2. Bacillus subtilis [50285] (4) picpic
          2. S1 RNA-binding domain of polyribonucleotide phosphorylase, PNPase [50287]
            1. Escherichia coli [50288] (1) picpic
          3. Translational initiation factor 1, IF1 [50290]
            1. Escherichia coli [50291] (1) picpic
          4. Rho termination factor, RNA-binding domain [68910]
            1. Escherichia coli [68911] (2) picpic
          5. C-terminal domain of eukaryotic initiation translation factor 5a (eIF5a) [50296]
            1. Archaeon Methanococcus jannaschii [50297] (1) picpic
            2. Archaeon Pyrobaculum aerophilum [50298] (1) picpic
          6. Ribosomal protein S17 [50304]
            1. Bacillus stearothermophilus [50306] (1) picpic
        4. DNA ligase/mRNA capping enzyme postcatalytic domain [50307] (2)
          1. RNA guanylyltransferase (mRNA capping enzyme) [50308]
            1. Chlorella virus, PBCV-1 [50309] (1) picpic
          2. ATP-dependent DNA ligase [50310]
            1. Bacteriophage T7 [50311] (1) picpic
        5. Phage ssDNA-binding proteins [50315] (2)
          1. Gene V protein [50316]
            1. Filamentous bacteriophage (f1, M13) [50317] (16) picpic
          2. Gene 32 protein (gp32) core [50319]
            1. Bacteriophage T4 [50320] (1) picpic
        6. RNA polymerase subunit RBP8 [50321] (1)
          1. RNA polymerase subunit RBP8 [50322]
            1. Baker's yeast (Saccharomyces cerevisiae) [50323] (1) picpic
      5. Inorganic pyrophosphatase [50324] (1)
        1. Inorganic pyrophosphatase [50325] (3)
          1. Inorganic pyrophosphatase [50326]
            1. Baker's yeast (Saccharomyces cerevisiae) [50327] (1) picpic
            2. Escherichia coli [50329] (4) picpic
            3. Thermus thermophilus [50330] (1) picpic
    29. beta-Trefoil [50352] (3)
      1. Cytokine [50353] (2)
        1. Fibroblast growth factors (FGF) [50354] (2)
          1. Basic FGF (FGF2) [50355]
            1. Human (Homo sapiens) [50356] (11) picpic
          2. Acidic FGF (FGF1) [50357]
            1. Human (Homo sapiens) [50359] (1) picpic
        2. Interleukin-1 (IL-1) [50362] (4)
          1. Interleukin-1beta [50363]
            1. Human (Homo sapiens) [50364] (11) picpic
            2. Mouse (Mus musculus) [50365] (2) picpic
          2. Interleukin-1 receptor antagonist protein [50366]
            1. Human (Homo sapiens) [50367] (1) picpic
          3. Interleukin-1alpha [50368]
            1. Human (Homo sapiens) [50369] (1) picpic
      2. STI-like [50386] (2)
        1. Kunitz (STI) inhibitors [50387] (4)
          1. Winged bean albumin 1 [50388]
            1. Goa bean (Psophocarpus tetragonolobus) [50389] (1) picpic
          2. Erythrina cafra trypsin inhibitor [50390]
            1. Erythrina caffra [50391] (1) picpic
          3. chymotrypsin inhibitor WCI [50392]
            1. Winged bean (Psophocarpus tetragonolobus) [50393] (2) picpic
          4. Soybean trypsin inhibitor [50394]
            1. Soybean (Glycine max) [50395] (1) picpic
        2. Clostridium neurotoxins, C-terminal domain [50399] (1)
          1. Tetanus neurotoxin [50400]
            1. Clostridium tetani [50401] (2) picpic
      3. Actin-crosslinking proteins [50405] (1)
        1. Histidine-rich actin-binding protein (hisactophilin) [50409] (1)
          1. Histidine-rich actin-binding protein (hisactophilin) [50410]
            1. Dictyostelium discoideum [50411] (2) picpic
    30. Reductase/isomerase/elongation factor common domain [50412] (2)
      1. Riboflavin synthase domain-like [63380] (1)
        1. Ferredoxin reductase FAD-binding domain-like [63381] (7)
          1. Ferredoxin reductase (flavodoxin reductase) N-terminal domain [50415]
            1. Spinach (Spinacia oleracea) [50416] (4) picpic
            2. Cyanobacterium (Anabaena sp.), pcc 7119 [50420] (3) picpic
            3. Escherichia coli [50421] (1) picpic
            4. Azotobacter vinelandii [50422] (1) picpic
          2. Nitrate reductase core domain [50425]
            1. Corn (Zea mays) [50426] (3) picpic
          3. cytochrome b5 reductase [50427]
            1. Pig (Sus scrofa), liver [50428] (1) picpic
          4. Phthalate dioxygenase reductase [50430]
            1. Pseudomonas cepacia, db01 [50431] (1) picpic
      2. Translation proteins [50447] (1)
        1. Elongation factors [50448] (2)
          1. Elongation factor Tu (EF-Tu), domain 2 [50449]
            1. Thermus aquaticus [50451] (1) picpic
          2. Elongation factor G (EF-G), domain II [50456]
            1. Thermus thermophilus [50457] (2) picpic
    31. Elongation factor/aminomethyltransferase common domain [50464] (1)
      1. EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain [50465] (1)
        1. EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain [50466] (1)
          1. Elongation factor Tu (EF-Tu) [50467]
            1. Thermus aquaticus [50469] (1) picpic
    32. FMN-binding split barrel [50474] (1)
      1. FMN-binding split barrel [50475] (1)
        1. PNP-oxidase like [50476] (1)
          1. FMN-binding protein [50477]
            1. Desulfovibrio vulgaris, strain Miyazaki F [50478] (1) picpic
    33. Trypsin-like serine proteases [50493] (1)
      1. Trypsin-like serine proteases [50494] (3)
        1. Prokaryotic proteases [50495] (5)
          1. Achromobacter protease [50496]
            1. Achromobacter lyticus, strain m497-1 [50497] (2) picpic
          2. alpha-Lytic protease [50498]
            1. Lysobacter enzymogenes, 495 [50499] (3) picpic
          3. Protease A [50500]
            1. Streptomyces griseus, strain k1 [50501] (2) picpic
          4. Trypsin [50504]
            1. Streptomyces griseus, strain k1 [50505] (1) picpic
          5. Serine proteinase [50506]
            1. Streptomyces fradiae [50507] (1) picpic
        2. Eukaryotic proteases [50514] (11)
          1. Trypsin(ogen) [50515]
            1. Cow (Bos taurus) [50516] (43) picpic
            2. Rat (Rattus norvegicus) [50518] (7) picpic
            3. North atlantic salmon (Salmo salar) [50520] (2) picpic
            4. Mold (Fusarium oxysporum) [50521] (1) picpic
          2. (alpha,gamma)-chymotrypsin(ogen) [50522]
            1. Cow (Bos taurus) [50523] (23) picpic
          3. Elastase [50536]
            1. Pig (Sus scrofa) [50538] (15) picpic
            2. Salmon (Salmo salar) [50539] (1) picpic
          4. Heparin binding protein, HBP [50544]
            1. Human (Homo sapiens) [50545] (2) picpic
          5. Chymase II (mast cell proteinase II) [50552]
            1. Human (Homo sapiens) [50554] (1) picpic
          6. Tonin [50557]
            1. Rat (Rattus rattus) [50558] (1) picpic
          7. Factor D [50563]
            1. Human (Homo sapiens) [50564] (3) picpic
        3. Viral proteases [50596] (2)
          1. Viral capsid protein [50597]
            1. Sindbis virus [50598] (7) picpic
          2. NS3 protease [50600]
            1. Human hepatitis C virus (HCV), different isolates [50601] (1) picpic
    34. mu transposase, C-terminal domain [50609] (1)
      1. mu transposase, C-terminal domain [50610] (1)
        1. mu transposase, C-terminal domain [50611] (1)
          1. mu transposase, C-terminal domain [50612]
            1. Bacteriophage mu [50613] (1) picpic
    35. Domain of alpha and beta subunits of F1 ATP synthase-like [50614] (1)
      1. Alanine racemase C-terminal domain-like [50621] (1)
        1. Alanine racemase [88682] (1)
          1. Alanine racemase [50623]
            1. Streptomyces lavendulae [110244] (1) picpic
    36. Acid proteases [50629] (1)
      1. Acid proteases [50630] (2)
        1. Retroviral protease (retropepsin) [50631] (4)
          1. Human immunodeficiency virus type 1 protease [50632]
            1. Human immunodeficiency virus type 1 [50633] (6) picpic
          2. Simian immunodeficiency virus (SIV) protease [50636]
            1. Simian immunodeficiency virus, different strains [50637] (3) picpic
          3. Feline immunodeficiency virus (FIV) protease [50638]
            1. Feline immunodeficiency virus [50639] (1) picpic
          4. EIAV protease [50644]
            1. Equine infectious anemia virus [50645] (2) picpic
        2. Pepsin-like [50646] (11)
          1. Endothiapepsin [50647]
            1. Chestnut blight fungus (Endothia parasitica) [50648] (1) picpic
          2. Acid protease [50649]
            1. Fungus (Penicillium janthinellum), penicillopepsin [50650] (5) picpic
            2. Bread mold (Rhizopus chinensis) [50651] (1) picpic
            3. Rhizomucor miehei [50652] (1) picpic
            4. Yeast (Candida albicans) [50653] (1) picpic
          3. Pepsin(ogen) [50658]
            1. Pig (Sus scrofa) [50659] (5) picpic
            2. Human (Homo sapiens), 3A [50660] (1) picpic
            3. Atlantic cod (Gadus morhua) [50662] (1) picpic
          4. Pepsin [50663]
            1. Mucor pusillus [50664] (1) picpic
          5. Chymosin (synonym: renin) [50667]
            1. Cow (Bos taurus) [50668] (3) picpic
            2. Human (Homo sapiens) [50669] (3) picpic
    37. ValRS/IleRS/LeuRS editing domain [50676] (1)
      1. ValRS/IleRS/LeuRS editing domain [50677] (1)
        1. ValRS/IleRS/LeuRS editing domain [50678] (1)
          1. Isoleucyl-tRNA synthetase (IleRS) [50679]
            1. Thermus thermophilus [50680] (1) picpic
    38. Double psi beta-barrel [50684] (2)
      1. Barwin-like endoglucanases [50685] (2)
        1. Endoglucanase V (Eng V) [50686] (1)
          1. Endoglucanase V (Eng V) [50687]
            1. Humicola insolens [50688] (3) picpic
        2. Barwin [50689] (1)
          1. Barwin [50690]
            1. Barley (Hordeum vulgare) [50691] (2) picpic
      2. ADC-like [50692] (1)
        1. Formate dehydrogenase/DMSO reductase, C-terminal domain [50696] (3)
          1. Dimethylsulfoxide reductase (DMSO reductase) [50697]
            1. Rhodobacter capsulatus [50699] (5) picpic
          2. Formate dehydrogenase H [50700]
            1. Escherichia coli [50701] (3) picpic
          3. Trimethylamine N-oxide reductase [50702]
            1. Shewanella massilia [50703] (1) picpic
    39. PH domain-like [50728] (1)
      1. PH domain-like [50729] (1)
        1. Pleckstrin-homology domain (PH domain) [50730] (7)
          1. Phospholipase C delta-1 [50731]
            1. Rat (Rattus norvegicus) [50732] (1) picpic
          2. beta-spectrin [50733]
            1. Mouse (Mus musculus), brain [50734] (2) picpic
            2. Fruit fly (Drosophila melanogaster) [50735] (1) picpic
          3. Pleckstrin, N-terminal domain [50740]
            1. Human (Homo sapiens) [50741] (1) picpic
          4. Son of sevenless-1 (sos-1) [50742]
            1. Mouse (Mus musculus) [50743] (1) picpic
            2. Human (Homo sapiens) [50744] (1) picpic
          5. G-protein coupled receptor kinase 2 (beta-adrenergic receptor kinase 1) [50747]
            1. Human (Homo sapiens) [50748] (1) picpic
    40. Herpes virus serine proteinase, assemblin [50788] (1)
      1. Herpes virus serine proteinase, assemblin [50789] (1)
        1. Herpes virus serine proteinase, assemblin [50790] (2)
          1. Human cytomegalovirus protease [50791]
            1. Human cytomegalovirus [50792] (1) picpic
          2. VZV protease [50797]
            1. Varicella-Zoster virus [50798] (1) picpic
    41. PK beta-barrel domain-like [50799] (1)
      1. PK beta-barrel domain-like [50800] (1)
        1. Pyruvate kinase beta-barrel domain [50801] (2)
          1. Pyruvate kinase (PK) [50802]
            1. Rabbit (Oryctolagus cuniculus) [50803] (1) picpic
            2. Cat (Felis catus) [50804] (1) picpic
    42. Lipocalins [50813] (1)
      1. Lipocalins [50814] (2)
        1. Retinol binding protein-like [50815] (6)
          1. Retinol binding protein [50816]
            1. Cow (Bos taurus) [50817] (6) picpic
            2. Pig (Sus scrofa domestica) [50818] (1) picpic
            3. Human (Homo sapiens) [50819] (3) picpic
          2. Lipocalin allergen [50824]
            1. Cow (Bos taurus), bos d 2 [50825] (1) picpic
          3. beta-Lactoglobulin [50827]
            1. Cow (Bos taurus) [50828] (4) picpic
          4. Major urinary protein/alpha-2u-globulin [50832]
            1. Mouse (Mus musculus) [50833] (1) picpic
        2. Fatty acid binding protein-like [50847] (9)
          1. Muscle fatty acid binding protein (m-fabp) [50848]
            1. Human (Homo sapiens) [50849] (4) picpic
          2. Intestinal fatty acid binding protein [50851]
            1. Rat (Rattus norvegicus) [50852] (8) picpic
          3. Epidermal fatty acid binding protein [50854]
            1. Human (Homo sapiens) [50855] (1) picpic
          4. Adipocyte lipid-binding protein, ALBP [50856]
            1. Mouse (Mus musculus) [50857] (10) picpic
          5. Fatty acid-binding protein [50858]
            1. Tobacco hornworm (Manduca sexta) [50859] (1) picpic
          6. Cellular retinoic-acid-binding protein (CRABP) [50861]
            1. Human (Homo sapiens), CRABP-II [50862] (4) picpic
          7. Cellular retinol-binding protein II (CRBP) [50864]
            1. Rat (Rattus norvegicus) [50865] (2) picpic
          8. Liver fatty acid binding protein [50866]
            1. Rat (Rattus norvegicus) [50867] (1) picpic
          9. Ileal lipid-binding protein [50870]
            1. Pig (Sus scrofa) [50871] (1) picpic
    43. Streptavidin-like [50875] (1)
      1. Avidin/streptavidin [50876] (1)
        1. Avidin/streptavidin [50877] (1)
          1. Streptavidin [50878]
            1. Streptomyces avidinii [50879] (11) picpic
    44. Cyclophilin-like [50890] (1)
      1. Cyclophilin-like [50891] (1)
        1. Cyclophilin (peptidylprolyl isomerase) [50892] (3)
          1. Cyclophilin (eukaryotic) [50893]
            1. Human (Homo sapiens), variant A [50894] (2) picpic
            2. Nematode (Brugia malayi) [50898] (2) picpic
          2. Peptidyl-prolyl cis-trans isomerase A, PpiA [50901]
            1. Escherichia coli [50902] (2) picpic
    45. Oncogene products [50903] (1)
      1. Oncogene products [50904] (1)
        1. Oncogene products [50905] (2)
          1. p14-TCL1 [50906]
            1. Human (Homo sapiens) [50907] (1) picpic
          2. p13-MTCP1 [50908]
            1. Human (Homo sapiens) [50909] (1) picpic
    46. 4-bladed beta-propeller [50922] (1)
      1. Hemopexin-like domain [50923] (1)
        1. Hemopexin-like domain [50924] (4)
          1. Hemopexin [50925]
            1. Rabbit (Oryctolagus cuniculus) [50926] (1) picpic
          2. Gelatinase A (MMP-2), C-terminal domain [50927]
            1. Human (Homo sapiens) [50928] (2) picpic
          3. Collagenase (MMP1), C-terminal domain [50929]
            1. Pig (Sus scrofa) [50930] (1) picpic
          4. Collagenase-3 (MMP-13), C-terminal domain [50931]
            1. Human (Homo sapiens) [50932] (1) picpic
    47. 6-bladed beta-propeller [50938] (1)
      1. Sialidases [50939] (1)
        1. Sialidases (neuraminidases) [50940] (6)
          1. Salmonella sialidase [50941]
            1. Salmonella typhimurium, strain lt2 [50942] (5) picpic
          2. Influenza neuraminidase [50943]
            1. Influenza A virus, different strains [50944] (31) picpic
            2. Influenza B virus, different strains [50945] (3) picpic
          3. Micromonospora sialidase, N-terminal domain [50946]
            1. Micromonospora viridifaciens [50947] (4) picpic
          4. Leech intramolecular trans-sialidase, C-terminal domain [50948]
            1. North american leech (Macrobdella decora) [50949] (5) picpic
          5. Vibrio cholerae sialidase [50950]
            1. Vibrio cholerae [50951] (1) picpic
    48. 7-bladed beta-propeller [50964] (1)
      1. Galactose oxidase, central domain [50965] (1)
        1. Galactose oxidase, central domain [50966] (1)
          1. Galactose oxidase, central domain [50967]
            1. Dactylium dendroides [50968] (3) picpic
    49. Glycosyl hydrolase domain [51010] (1)
      1. Glycosyl hydrolase domain [51011] (1)
        1. alpha-Amylases, C-terminal beta-sheet domain [51012] (15)
          1. Bacterial alpha-Amylase [51013]
            1. Bacillus licheniformis [51014] (2) picpic
            2. Pseudoalteromonas haloplanctis (Alteromonas haloplanctis) [51015] (2) picpic
            3. Bacillus subtilis [51016] (1) picpic
          2. Cyclodextrin glycosyltransferase [51018]
            1. Bacillus circulans, different strains [51019] (18) picpic
            2. Bacillus stearothermophilus [51020] (1) picpic
            3. Thermoanaerobacterium thermosulfurigenes, EM1 [51023] (2) picpic
          3. Animal alpha-amylase [51024]
            1. Pig (Sus scrofa) [51025] (5) picpic
            2. Human (Homo sapiens) [51026] (3) picpic
            3. Yellow mealworm (Tenebrio molitor), larva [51027] (1) picpic
          4. Fungal alpha-amylase [51028]
            1. Aspergillus niger, acid amylase [51029] (1) picpic
            2. Aspergillus oryzae, Taka-amylase [51030] (2) picpic
          5. Isoamylase [51036]
            1. Pseudomonas amyloderamosa [51037] (1) picpic
          6. G4-amylase (1,4-alpha-D-glucan maltotetrahydrolase) [51038]
            1. Pseudomonas stutzeri [51039] (4) picpic
          7. Plant alpha-amylase [51040]
            1. Barley (Hordeum vulgare), seeds, AMY2 isozyme [51041] (2) picpic
          8. Oligo-1,6-glucosidase [51042]
            1. Bacillus cereus [51043] (1) picpic
    50. WW domain-like [51044] (1)
      1. Carbohydrate binding domain [51055] (1)
        1. Carbohydrate binding domain [51056] (1)
          1. Cellulose-binding domain of endoglucanase Z [51057]
            1. Erwinia chrysanthemi [51058] (1) picpic
    51. Carbonic anhydrase [51068] (1)
      1. Carbonic anhydrase [51069] (1)
        1. Carbonic anhydrase [51070] (4)
          1. Carbonic anhydrase [51071]
            1. Human (Homo sapiens), erythrocytes, isozyme I [51072] (7) picpic
            2. Human (Homo sapiens), erythrocytes, isozyme II [51073] (105) picpic
            3. Mouse (Mus musculus), isozyme IV [51077] (2) picpic
            4. Mouse (Mus musculus), liver, isozyme V [51078] (1) picpic
    52. Bacteriochlorophyll A protein [51080] (1)
      1. Bacteriochlorophyll A protein [51081] (1)
        1. Bacteriochlorophyll A protein [51082] (1)
          1. Bacteriochlorophyll A protein [51083]
            1. Prosthecochloris aestuarii, strain 2k [51084] (1) picpic
    53. beta-Prism I [51091] (1)
      1. delta-Endotoxin (insectocide), middle domain [51096] (1)
        1. delta-Endotoxin (insectocide), middle domain [51097] (2)
          1. delta-Endotoxin (insectocide), middle domain [51098]
            1. Bacillus thuringiensis tenebrionis, CRYIIIA (BT13) [51099] (1) picpic
            2. Bacillus thuringiensis, CRYIA (A) [51100] (1) picpic
    54. beta-Prism II [51109] (1)
      1. alpha-D-mannose-specific plant lectins [51110] (1)
        1. alpha-D-mannose-specific plant lectins [51111] (1)
          1. Lectin (agglutinin) [51112]
            1. Snowdrop (Galanthus nivalis) [51113] (1) picpic
    55. Single-stranded right-handed beta-helix [51125] (2)
      1. beta-Roll [51120] (1)
        1. Serralysin-like metalloprotease, C-terminal domain [51121] (2)
          1. Metalloprotease [51122]
            1. Pseudomonas aeruginosa [51123] (1) picpic
            2. Serratia marcescens [51124] (2) picpic
      2. Pectin lyase-like [51126] (4)
        1. Pectate lyase-like [51127] (2)
          1. Pectate lyase [51128]
            1. Erwinia chrysanthemi, type C [51129] (2) picpic
            2. Erwinia chrysanthemi, type E [51130] (1) picpic
        2. Pectin lyase [51133] (1)
          1. Pectin lyase [51134]
            1. Aspergillus niger, type A [51135] (1) picpic
        3. Galacturonase [51137] (2)
          1. Rhamnogalacturonase A [51138]
            1. Aspergillus aculeatus [51139] (1) picpic
          2. Polygalacturonase [51140]
            1. Erwinia carotovora, subsp. carotovora [51141] (1) picpic
        4. P22 tailspike protein [51150] (1)
          1. P22 tailspike protein [51151]
            1. Salmonella phage P22 [51152] (5) picpic
    56. Single-stranded left-handed beta-helix [51160] (1)
      1. Trimeric LpxA-like enzymes [51161] (3)
        1. UDP N-acetylglucosamine acyltransferase [51162] (1)
          1. UDP N-acetylglucosamine acyltransferase [51163]
            1. Escherichia coli, gene lpxA [51164] (1) picpic
        2. Tetrahydrodipicolinate-N-succinlytransferase, THDP-succinlytransferase, DapD [51165] (1)
          1. Tetrahydrodipicolinate-N-succinlytransferase, THDP-succinlytransferase, DapD [51166]
            1. Mycobacterium bovis [51167] (2) picpic
        3. Galactoside acetyltransferase-like [51168] (1)
          1. Xenobiotic acetyltransferase [51169]
            1. Pseudomonas aeruginosa [51170] (2) picpic
    57. Double-stranded beta-helix [51181] (4)
      1. RmlC-like cupins [51182] (2)
        1. Germin/Seed storage 7S protein [51187] (1)
          1. Seed storage 7S protein [51188]
            1. French bean (Phaseolus vulgaris), phaseolin [51189] (2) picpic
        2. Type I phosphomannose isomerase [51191] (1)
          1. Phosphomannose isomerase [51192]
            1. Yeast (Candida albicans) [51193] (1) picpic
      2. Clavaminate synthase-like [51197] (1)
        1. Penicillin synthase-like [51198] (2)
          1. Isopenicillin N synthase [51199]
            1. Emericella nidulans [51200] (2) picpic
          2. Deacetoxycephalosporin C synthase [51201]
            1. Streptomyces clavuligerus [51202] (3) picpic
      3. cAMP-binding domain-like [51206] (1)
        1. cAMP-binding domain [51210] (1)
          1. Regulatory subunit of Protein kinase A [51213]
            1. Cow (Bos taurus) [51214] (2) picpic
      4. Regulatory protein AraC [51215] (1)
        1. Regulatory protein AraC [51216] (1)
          1. Regulatory protein AraC [51217]
            1. Escherichia coli [51218] (1) picpic
    58. Barrel-sandwich hybrid [51229] (3)
      1. Single hybrid motif [51230] (1)
        1. Biotinyl/lipoyl-carrier proteins and domains [51231] (7)
          1. Biotinyl domain of acetyl-CoA carboxylase [51232]
            1. Escherichia coli [51233] (2) picpic
          2. Protein H of glycine cleavage system [51236]
            1. Pea (Pisum sativum) [51237] (1) picpic
          3. Lipoyl domain of dihydrolipoamide acetyltransferase [51238]
            1. Bacillus stearothermophilus [51239] (2) picpic
            2. Azotobacter vinelandii [51240] (2) picpic
            3. Human (Homo sapiens) [51242] (1) picpic
          4. Lipoyl domain of the 2-oxoglutarate dehydrogenase complex [51243]
            1. Azotobacter vinelandii [51244] (2) picpic
            2. Escherichia coli [51245] (1) picpic
      2. Rudiment single hybrid motif [51246] (1)
        1. Cytochrome f, small domain [51256] (1)
          1. Cytochrome f, small domain [51257]
            1. Turnip (Brassica rapa) [51258] (2) picpic
      3. Duplicated hybrid motif [51261] (1)
        1. Glucose permease-like [51262] (3)
          1. Glucose permease IIa domain, IIa-glc [51263]
            1. Bacillus subtilis [51264] (2) picpic
            2. Mycoplasma capricolum [51265] (1) picpic
          2. Glucose-specific factor III (glsIII) [51266]
            1. Escherichia coli [51267] (2) picpic
    59. beta-clip [51268] (4)
      1. AFP III-like domain [51269] (1)
        1. AFP III-like domain [51270] (2)
          1. Type III antifreeze protein, AFP III [51271]
            1. Ocean pout (Macrozoarces americanus), different isoforms [51272] (12) picpic
            2. Antarctic eel pout (Austrolycichthys brachycephalus) and (Lycodichthys dearborni), RD3 isoform [51273] (2) picpic
      2. SET domain [82199] (1)
        1. Histone lysine methyltransferases [82200] (1)
          1. Histone H3 K4-specific methyltransferase SET7/9 catalytic domain [82205]
            1. Human (Homo sapiens) [82206] (2) picpic
      3. dUTPase-like [51283] (1)
        1. dUTPase-like [51284] (2)
          1. Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) [51285]
            1. Escherichia coli [51286] (1) picpic
            2. Equine infectious anemia virus [51288] (2) picpic
      4. Tlp20, baculovirus telokin-like protein [51289] (1)
        1. Tlp20, baculovirus telokin-like protein [51290] (1)
          1. Tlp20, baculovirus telokin-like protein [51291]
            1. AcMNPV (Autographa californica nuclear polyhedrosis virus) [51292] (1) picpic
    60. Hedgehog/intein (Hint) domain [51293] (1)
      1. Hedgehog/intein (Hint) domain [51294] (2)
        1. Hedgehog C-terminal (Hog) autoprocessing domain [51295] (1)
          1. Hedgehog [51296]
            1. Fruit fly (Drosophila melanogaster) [51297] (1) picpic
        2. Intein (protein splicing domain) [51298] (1)
          1. GyrA intein [51303]
            1. Mycobacterium xenopi [51304] (1) picpic
    61. Cyanovirin-N [51321] (1)
      1. Cyanovirin-N [51322] (1)
        1. Cyanovirin-N [51323] (1)
          1. Cyanovirin-N [51324]
            1. Cyanobacterium (Nostoc ellipsosporum) [51325] (2) picpic
    62. Epsilon subunit of F1F0-ATP synthase N-terminal domain [51343] (1)
      1. Epsilon subunit of F1F0-ATP synthase N-terminal domain [51344] (1)
        1. Epsilon subunit of F1F0-ATP synthase N-terminal domain [51345] (1)
          1. Epsilon subunit of F1F0-ATP synthase N-terminal domain [51346]
            1. Escherichia coli [51347] (1) picpic
  3. Alpha and beta proteins (a/b) [51349] (71)
    Mainly parallel beta sheets (beta-alpha-beta units)
    1. TIM beta/alpha-barrel [51350] (16)
      1. Triosephosphate isomerase (TIM) [51351] (1)
        1. Triosephosphate isomerase (TIM) [51352] (2)
          1. Triosephosphate isomerase [51353]
            1. Trypanosoma brucei [51357] (4) picpic
            2. Leishmania mexicana [51360] (1) picpic
      2. Ribulose-phoshate binding barrel [51366] (1)
        1. Tryptophan biosynthesis enzymes [51381] (4)
          1. N-(5'phosphoribosyl)antranilate isomerase, PRAI [51382]
            1. Escherichia coli [51383] (1) picpic
            2. Thermotoga maritima [51384] (1) picpic
          2. Indole-3-glycerophosphate synthase, IPGS [51385]
            1. Escherichia coli [51386] (1) picpic
            2. Archaeon Sulfolobus solfataricus [51387] (4) picpic
      3. FMN-linked oxidoreductases [51395] (1)
        1. FMN-linked oxidoreductases [51396] (2)
          1. Old yellow enzyme (OYE) [51401]
            1. Brewer's yeast (Saccharomyces carlsbergensis) [51402] (3) picpic
          2. Glycolate oxidase [51404]
            1. Spinach (Spinacia oleracea) [51405] (3) picpic
      4. Inosine monophosphate dehydrogenase (IMPDH) [51412] (1)
        1. Inosine monophosphate dehydrogenase (IMPDH) [51413] (1)
          1. Inosine monophosphate dehydrogenase (IMPDH) [51414]
            1. Tritrichomonas foetus [51417] (1) picpic
      5. PLP-binding barrel [51419] (1)
        1. "Hypothetical" protein ybl036c [51427] (1)
          1. "Hypothetical" protein ybl036c [51428]
            1. Baker's yeast (Saccharomyces cerevisiae) [51429] (1) picpic
      6. NAD(P)-linked oxidoreductase [51430] (1)
        1. Aldo-keto reductases (NADP) [51431] (5)
          1. FR-1 (fibroblast growth factor-induced) protein [51432]
            1. Mouse (Mus musculus) [51433] (1) picpic
          2. Aldose reductase (aldehyde reductase) [51436]
            1. Human (Homo sapiens) [51437] (10) picpic
            2. Pig (Sus scrofa) [51438] (5) picpic
          3. 3-alpha-hydroxysteroid dehydrogenase [51439]
            1. Rat (Rattus norvegicus) [51440] (1) picpic
          4. 2,5-diketo-D-gluconic acid reductase A [51443]
            1. Corynebacterium sp. [51444] (1) picpic
      7. (Trans)glycosidases [51445] (5)
        1. Amylase, catalytic domain [51446] (16)
          1. Bacterial alpha-amylase [51447]
            1. Bacillus licheniformis [51448] (2) picpic
            2. Pseudoalteromonas haloplanctis (Alteromonas haloplanctis) [51449] (2) picpic
            3. Bacillus subtilis [51450] (1) picpic
          2. Cyclodextrin glycosyltransferase [51452]
            1. Bacillus circulans, different strains [51453] (18) picpic
            2. Bacillus stearothermophilus [51454] (1) picpic
            3. Thermoanaerobacterium thermosulfurigenes, EM1 [51457] (2) picpic
          3. Animal alpha-amylase [51458]
            1. Pig (Sus scrofa) [51459] (5) picpic
            2. Human (Homo sapiens) [51460] (3) picpic
            3. Yellow mealworm (Tenebrio molitor), larva [51461] (1) picpic
          4. Fungal alpha-amylases [51462]
            1. Aspergillus niger, acid amylase [51463] (1) picpic
            2. Aspergillus oryzae, Taka-amylase [51464] (2) picpic
          5. Isoamylase, central domain [51470]
            1. Pseudomonas amyloderamosa [51471] (1) picpic
          6. G4-amylase (1,4-alpha-D-glucan maltotetrahydrolase) [51472]
            1. Pseudomonas stutzeri [51473] (4) picpic
          7. Plant alpha-amylase [51474]
            1. Barley (Hordeum vulgare), seeds, AMY2 isozyme [51475] (2) picpic
          8. Oligo-1,6, glucosidase [51476]
            1. Bacillus cereus [51477] (1) picpic
          9. beta-Amylase [51481]
            1. Soybean (Glycine max) [51482] (6) picpic
        2. beta-glycanases [51487] (9)
          1. Xylanase [51488]
            1. Penicillium simplicissimum [51490] (1) picpic
          2. Endoglucanase CelA [51491]
            1. Clostridium cellulolyticum [51492] (1) picpic
          3. Endoglucanase CelC [51493]
            1. Clostridium thermocellum [51494] (3) picpic
          4. Endoglucanase Cel5a [51499]
            1. Bacillus agaradhaerens [51500] (3) picpic
          5. Plant beta-glucanases [51507]
            1. Barley (Hordeum vulgare), 1,3-1,4-beta-glucanase [51509] (1) picpic
          6. Xylanase A, catalytic core [51514]
            1. Streptomyces lividans [51515] (1) picpic
            2. Pseudomonas fluorescens [51517] (1) picpic
            3. Thermoascus aurantiacus [51518] (1) picpic
            4. Cellulomonas fimi [51520] (4) picpic
        3. Family 1 of glycosyl hydrolase [51521] (3)
          1. Plant beta-glucosidase (myrosinase) [51522]
            1. White mustard (Sinapis alba) [51523] (1) picpic
            2. Creeping white clover (Trifolium repens) [51524] (1) picpic
          2. 6-phospho-beta-D-galactosidase, PGAL [51526]
            1. Lactococcus lactis [51527] (1) picpic
        4. Type II chitinase [51534] (6)
          1. Hevamine A (chitinase/lysozyme) [51535]
            1. Para rubber tree (Hevea brasiliensis) [51536] (3) picpic
          2. Seed storage protein [51537]
            1. Vicia narbonensis, Narbonin [51538] (1) picpic
            2. Jack bean (Canavalia ensiformis), Concanavalin B [51539] (1) picpic
          3. Endo-beta-N-acetylglucosaminidase [51540]
            1. Flavobacterium meningosepticum, endoglycosidase F1 [51541] (1) picpic
            2. Streptomyces plicatus, endoglycosidase H [51543] (1) picpic
          4. Chitinase A, catalytic domain [51544]
            1. Serratia marcescens [51545] (1) picpic
        5. beta-N-acetylhexosaminidase catalytic domain [51550] (1)
          1. Bacterial chitobiase (beta-N-acetylhexosaminidase) [51551]
            1. Serratia marcescens [51552] (2) picpic
      8. Metallo-dependent hydrolases [51556] (2)
        1. Adenosine deaminase (ADA) [51557] (1)
          1. Adenosine deaminase (ADA) [51558]
            1. Mouse (Mus musculus) [51559] (6) picpic
        2. Phosphotriesterase-like [51564] (1)
          1. Phosphotriesterase (parathion hydrolase, PTE) [51565]
            1. Pseudomonas diminuta [51566] (1) picpic
      9. Aldolase [51569] (3)
        1. Class I aldolase [51570] (1)
          1. Fructose-1,6-bisphosphate aldolase [51576]
            1. Human (Homo sapiens), muscle isozyme [51577] (2) picpic
        2. Class II FBP aldolase [51591] (1)
          1. Fructose-bisphosphate aldolase (FBP aldolase) [51592]
            1. Escherichia coli [51593] (1) picpic
        3. 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51594] (1)
          1. 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51595]
            1. Baker's yeast (Saccharomyces cerevisiae) [51596] (1) picpic
      10. Enolase C-terminal domain-like [51604] (2)
        1. Enolase [51605] (2)
          1. Enolase [51606]
            1. Baker's yeast (Saccharomyces cerevisiae) [51607] (7) picpic
            2. Lobster (Homarus vulgaris) [51608] (2) picpic
        2. D-glucarate dehydratase-like [51609] (3)
          1. D-glucarate dehydratase [51610]
            1. Pseudomonas putida [51611] (1) picpic
          2. Mandelate racemase [51617]
            1. Pseudomonas putida [51618] (6) picpic
          3. Chlormuconate cycloisomerase [51619]
            1. Alcaligenes eutrophus [51620] (1) picpic
      11. Phosphoenolpyruvate/pyruvate domain [51621] (3)
        1. Pyruvate kinase [51622] (2)
          1. Pyruvate kinase, N-terminal domain [51623]
            1. Cat (Felis catus) [51624] (1) picpic
            2. Rabbit (Oryctolagus cuniculus) [51625] (1) picpic
        2. Pyruvate phosphate dikinase, C-terminal domain [51629] (1)
          1. Pyruvate phosphate dikinase, C-terminal domain [51630]
            1. Clostridium symbiosum [51631] (1) picpic
        3. Phosphoenolpyruvate carboxylase [51632] (1)
          1. Phosphoenolpyruvate carboxylase [51633]
            1. Escherichia coli [51634] (1) picpic
      12. Xylose isomerase-like [51658] (1)
        1. Xylose isomerase [51665] (2)
          1. D-xylose isomerase [51666]
            1. Streptomyces albus [51667] (1) picpic
            2. Streptomyces rubiginosus [51670] (15) picpic
      13. Bacterial luciferase-like [51679] (1)
        1. Non-fluorescent flavoprotein (luxF, FP390) [51683] (1)
          1. Non-fluorescent flavoprotein (luxF, FP390) [51684]
            1. Photobacterium leiognathi [51685] (1) picpic
      14. PLC-like phosphodiesterases [51695] (1)
        1. Bacterial PLC [51699] (2)
          1. Phosphatidylinositol-specific phospholipase C [51700]
            1. Bacillus cereus [51701] (9) picpic
            2. Listeria monocytogenes [51702] (2) picpic
      15. tRNA-guanine transglycosylase [51713] (1)
        1. tRNA-guanine transglycosylase [51714] (1)
          1. Queosine tRNA-guanine transglycosylase [51715]
            1. Zymomonas mobilis [51716] (4) picpic
      16. Dihydropteroate synthetase-like [51717] (1)
        1. Dihydropteroate synthetase [51718] (1)
          1. Dihydropteroate synthetase [51719]
            1. Escherichia coli [51720] (3) picpic
    2. NAD(P)-binding Rossmann-fold domains [51734] (1)
      1. NAD(P)-binding Rossmann-fold domains [51735] (7)
        1. Alcohol dehydrogenase-like, C-terminal domain [51736] (1)
          1. Alcohol dehydrogenase [51737]
            1. Horse (Equus caballus) [51738] (6) picpic
        2. Tyrosine-dependent oxidoreductases [51751] (9)
          1. Uridine diphosphogalactose-4-epimerase (UDP-galactose 4-epimerase) [51752]
            1. Escherichia coli [51753] (13) picpic
          2. Sepiapterin reductase [51767]
            1. Mouse (Mus musculus) [51768] (3) picpic
          3. Dihydropteridin reductase (pteridine reductase) [51769]
            1. Rat (Rattus norvegicus) [51770] (1) picpic
            2. Human (Homo sapiens) [51771] (1) picpic
          4. Human estrogenic 17beta-hydroxysteroid dehydrogenase [51772]
            1. Human (Homo sapiens) [51773] (6) picpic
          5. Cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase [51780]
            1. Pseudomonas sp., lb400 [51781] (1) picpic
          6. Enoyl-ACP reductase [51791]
            1. Oil seed rape (Brassica napus) [51792] (2) picpic
            2. Mycobacterium tuberculosis, TB, gene InhA [51793] (3) picpic
          7. Tropinone reductase [51795]
            1. Jimsonweed (Datura stramonium), II [51797] (1) picpic
        3. Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (5)
          1. Diaminopimelic acid dehydrogenase (DAPDH) [51819]
            1. Corynebacterium glutamicum [51820] (1) picpic
          2. Dihydrodipicolinate reductase [51821]
            1. Escherichia coli [51822] (4) picpic
            2. Thermotoga maritima [110417] (2) picpic
          3. Glucose 6-phosphate dehydrogenase, N-terminal domain [51827]
            1. Leuconostoc mesenteroides [51828] (1) picpic
          4. Virulence factor MviM [110421]
            1. Escherichia coli [110422] (2) picpic
        4. Formate/glycerate dehydrogenases, NAD-domain [51830] (1)
          1. D-2-hydroxyisocaproate dehydrogenase [51835]
            1. Lactobacillus casei [51836] (1) picpic
        5. LDH N-terminal domain-like [51848] (8)
          1. Malate dehydrogenase [51849]
            1. Escherichia coli [51853] (2) picpic
          2. Lactate dehydrogenase [51859]
            1. Pig (Sus scrofa) [51860] (1) picpic
            2. Mouse (Mus musculus) [51861] (1) picpic
            3. Dogfish (Squalus acanthias) [51862] (3) picpic
            4. Malaria parasite (Plasmodium falciparum) [51863] (1) picpic
            5. Bacillus stearothermophilus [51864] (2) picpic
            6. Lactobacillus casei [51865] (1) picpic
            7. Thermotoga maritima [51867] (1) picpic
        6. 6-phosphogluconate dehydrogenase-like, N-terminal domain [51868] (2)
          1. 6-phosphogluconate dehydrogenase [51871]
            1. Sheep (Ovis orientalis aries) [51872] (5) picpic
          2. N-(1-D-carboxylethyl)-L-norvaline dehydrogenase [51879]
            1. Arthrobacter, strain 1c [51880] (1) picpic
        7. Aminoacid dehydrogenase-like, C-terminal domain [51883] (1)
          1. Glutamate dehydrogenase [51884]
            1. Clostridium symbiosum [51885] (2) picpic
    3. FAD/NAD(P)-binding domain [51904] (1)
      1. FAD/NAD(P)-binding domain [51905] (3)
        1. FAD-linked reductases, N-terminal domain [51913] (4)
          1. Cholesterol oxidase of GMC family [51914]
            1. Brevibacterium sterolicum [51915] (2) picpic
          2. Glucose oxidase [51924]
            1. Aspergillus niger [51925] (1) picpic
          3. p-Hydroxybenzoate hydroxylase, PHBH [51917]
            1. Pseudomonas fluorescens [51918] (11) picpic
            2. Pseudomonas aeruginosa [51919] (13) picpic
        2. GDI-like N domain [51931] (1)
          1. Guanine nucleotide dissociation inhibitor, GDI [51932]
            1. Cow (Bos taurus) [51933] (1) picpic
        3. FAD/NAD-linked reductases, N-terminal and central domains [51943] (6)
          1. Glutathione reductase [51944]
            1. Human (Homo sapiens) [51945] (30) picpic
          2. Thioredoxin reductase [51950]
            1. Escherichia coli [51951] (6) picpic
            2. Mouse-ear cress (Arabidopsis thaliana) [51952] (2) picpic
          3. NADH peroxidase [51955]
            1. Enterococcus faecalis [51956] (14) picpic
          4. Dihydrolipoamide dehydrogenase [51959]
            1. Pseudomonas putida [51960] (2) picpic
            2. Neisseria meningitidis [51964] (4) picpic
    4. MurCD N-terminal domain [51983] (1)
      1. MurCD N-terminal domain [51984] (1)
        1. MurCD N-terminal domain [51985] (1)
          1. UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase MurD [51986]
            1. Escherichia coli [51987] (1) picpic
    5. 7-stranded beta/alpha barrel [51988] (1)
      1. Glycosyl hydrolases family 6, cellulases [51989] (1)
        1. Glycosyl hydrolases family 6, cellulases [51990] (2)
          1. Cellulase E2 [51991]
            1. Thermomonospora fusca, strain yx [51992] (1) picpic
          2. Cellobiohydrolase II (Cel6) [51993]
            1. Trichoderma reesei, Cel6a [51994] (1) picpic
    6. PFL-like glycyl radical enzymes [51997] (1)
      1. PFL-like glycyl radical enzymes [51998] (1)
        1. R1 subunit of ribonucleotide reductase, C-terminal domain [52002] (1)
          1. R1 subunit of ribonucleotide reductase, C-terminal domain [52003]
            1. Escherichia coli [52004] (1) picpic
    7. The "swivelling" beta/beta/alpha domain [52008] (3)
      1. Phosphohistidine domain [52009] (2)
        1. Pyruvate phosphate dikinase, central domain [52010] (1)
          1. Pyruvate phosphate dikinase, central domain [52011]
            1. Clostridium symbiosum [52012] (1) picpic
        2. N-terminal domain of enzyme I of the PEP:sugar phosphotransferase system [52013] (1)
          1. N-terminal domain of enzyme I of the PEP:sugar phosphotransferase system [52014]
            1. Escherichia coli [52015] (7) picpic
      2. LeuD-like [52016] (1)
        1. LeuD-like [52017] (2)
          1. Aconitase A, C-terminal domain [52018]
            1. Pig (Sus scrofa) [52019] (3) picpic
            2. Cow (Bos taurus) [52020] (7) picpic
      3. GroEL apical domain-like [52029] (2)
        1. GroEL-like chaperone, apical domain [52030] (1)
          1. GroEL, A domain [52031]
            1. Escherichia coli [52032] (3) picpic
        2. Group II chaperonin (CCT, TRIC), apical domain [52034] (1)
          1. Thermosome, A-domain [52035]
            1. Archaeon Thermoplasma acidophilum, alpha chain [100946] (2) picpic
    8. Barstar-like [52037] (1)
      1. Barstar (barnase inhibitor) [52038] (1)
        1. Barstar (barnase inhibitor) [52039] (1)
          1. Barstar (barnase inhibitor) [52040]
            1. Bacillus amyloliquefaciens [52041] (3) picpic
    9. Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) [52046] (1)
      1. RNI-like [52047] (1)
        1. 28-residue LRR [52048] (1)
          1. Ribonuclease inhibitor [52049]
            1. Pig (Sus scrofa) [52050] (1) picpic
    10. SpoIIaa-like [52086] (2)
      1. CRAL/TRIO domain [52087] (1)
        1. CRAL/TRIO domain [52088] (1)
          1. C-terminal domain of phosphatidylinositol transfer protein sec14p [52089]
            1. Baker's yeast (Saccharomyces cerevisiae) [52090] (1) picpic
      2. Anti-sigma factor antagonist SpoIIaa [52091] (1)
        1. Anti-sigma factor antagonist SpoIIaa [52092] (1)
          1. Anti-sigma factor antagonist SpoIIaa [52093]
            1. Bacillus subtilis [52094] (2) picpic
    11. ClpP/crotonase [52095] (1)
      1. ClpP/crotonase [52096] (1)
        1. Biotin dependent carboxylase carboxyltransferase domain [89572] (1)
          1. Glutaconyl-CoA decarboxylase A subunit [102210]
            1. Acidaminococcus fermentans [102211] (2) picpic
    12. DNA glycosylase [52140] (1)
      1. DNA glycosylase [52141] (1)
        1. Uracil-DNA glycosylase [52142] (2)
          1. Uracil-DNA glycosylase [52143]
            1. Human (Homo sapiens) [52144] (1) picpic
            2. Herpes simplex virus type 1 [52145] (2) picpic
    13. Aminoacid dehydrogenase-like, N-terminal domain [53222] (1)
      1. Aminoacid dehydrogenase-like, N-terminal domain [53223] (1)
        1. Aminoacid dehydrogenases [53224] (1)
          1. Glutamate dehydrogenase [53225]
            1. Clostridium symbiosum [53226] (2) picpic
    14. Flavodoxin-like [52171] (6)
      1. CheY-like [52172] (1)
        1. CheY-related [52173] (6)
          1. CheY protein [52174]
            1. Escherichia coli [52175] (7) picpic
            2. Salmonella typhimurium [52176] (4) picpic
            3. Thermotoga maritima [52177] (2) picpic
          2. Nitrate/nitrite response regulator (NarL), receiver domain [52178]
            1. Escherichia coli [52179] (1) picpic
          3. NTRC receiver domain [52180]
            1. Salmonella typhimurium [52181] (1) picpic
          4. Sporulation response regulator Spo0F [52188]
            1. Bacillus subtilis [52189] (3) picpic
      2. Flavoproteins [52218] (1)
        1. Flavodoxin-related [52219] (6)
          1. Flavodoxin [52220]
            1. Chondrus crispus [52221] (1) picpic
            2. Desulfovibrio vulgaris [52222] (12) picpic
            3. Anabaena, pcc 7119 and 7120 [52223] (3) picpic
            4. Escherichia coli [52224] (1) picpic
            5. Anacystis nidulans and Synechococcus, pcc 7942 [52225] (1) picpic
            6. Clostridium beijerinckii [52226] (16) picpic
      3. Cobalamin (vitamin B12)-binding domain [52242] (1)
        1. Cobalamin (vitamin B12)-binding domain [52243] (2)
          1. Glutamate mutase, small subunit [52246]
            1. Clostridium tetanomorphum [52247] (1) picpic
            2. Clostridium cochlearium [52248] (1) picpic
      4. SGNH hydrolase [52266] (2)
        1. Esterase [52267] (1)
          1. Esterase [52268]
            1. Streptomyces scabies [52269] (3) picpic
        2. Acetylhydrolase [52273] (1)
          1. Platelet-activating factor acetylhydrolase [52274]
            1. Cow (Bos taurus), alpha1 [52275] (4) picpic
      5. Formate/glycerate dehydrogenase catalytic domain-like [52283] (1)
        1. Formate/glycerate dehydrogenases, substrate-binding domain [52284] (1)
          1. D-2-hydroxyisocaproate dehydrogenase [52289]
            1. Lactobacillus casei [52290] (1) picpic
      6. Class I glutamine amidotransferase-like [52317] (1)
        1. Class I glutamine amidotransferases (GAT) [52318] (1)
          1. FGAM synthase PurL, amidotransferase domain [110484]
            1. Salmonella typhimurium [110485] (1) picpic
    15. Ferredoxin reductase-like, C-terminal NADP-linked domain [52342] (1)
      1. Ferredoxin reductase-like, C-terminal NADP-linked domain [52343] (2)
        1. Reductases [52344] (6)
          1. Ferredoxin reductase (flavodoxin reductase) [52345]
            1. Spinach (Spinacia oleracea) [52346] (4) picpic
            2. Cyanobacterium (Anabaena sp.), pcc 7119 [52350] (3) picpic
            3. Escherichia coli [52351] (1) picpic
            4. Azotobacter vinelandii [52352] (1) picpic
          2. Nitrate reductase [52355]
            1. Corn (Zea mays) [52356] (3) picpic
          3. cytochrome b5 reductase [52357]
            1. Pig (Sus scrofa), liver [52358] (1) picpic
        2. Aromatic dioxygenase reductase-like [52359] (1)
          1. Phthalate dioxygenase reductase [52360]
            1. Pseudomonas cepacia, db01 [52361] (1) picpic
    16. Adenine nucleotide alpha hydrolase-like [52373] (2)
      1. Nucleotidylyl transferase [52374] (1)
        1. Class I aminoacyl-tRNA synthetases (RS), catalytic domain [52375] (4)
          1. Tyrosyl-tRNA synthetase (TyrRS) [52376]
            1. Bacillus stearothermophilus, nca 1503 [52377] (3) picpic
          2. Glutamyl-tRNA synthetase (GluRS) [52382]
            1. Thermus thermophilus [52383] (1) picpic
          3. Methionyl-tRNA synthetase (MetRS) [52384]
            1. Thermus thermophilus [52385] (1) picpic
          4. Isoleucyl-tRNA synthetase (IleRS) [52387]
            1. Thermus thermophilus [52388] (1) picpic
      2. Adenine nucleotide alpha hydrolases-like [52402] (1)
        1. Phosphoadenylyl sulphate (PAPS) reductase [52410] (1)
          1. Phosphoadenylyl sulphate (PAPS) reductase [52411]
            1. Escherichia coli [52412] (1) picpic
    17. Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain [52417] (1)
      1. Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain [52418] (1)
        1. Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain [52419] (1)
          1. Thymidine phosphorylase [52420]
            1. Escherichia coli [52421] (3) picpic
    18. Cryptochrome/photolyase, N-terminal domain [52424] (1)
      1. Cryptochrome/photolyase, N-terminal domain [52425] (1)
        1. Cryptochrome/photolyase, N-terminal domain [52426] (1)
          1. DNA photolyase [52427]
            1. Anacystis nidulans [52429] (1) picpic
    19. PIN domain-like [88722] (1)
      1. PIN domain-like [88723] (1)
        1. 5' to 3' exonuclease catalytic domain [53045] (3)
          1. T4 RNase H [53046]
            1. Bacteriophage T4 [53047] (1) picpic
          2. 5' to 3' exonuclease domain of DNA polymerase Taq [53048]
            1. Thermus aquaticus [53049] (1) picpic
          3. Flap endonuclease-1 (Fen-1 nuclease) [53052]
            1. Archaeon Methanococcus jannaschii [53053] (2) picpic
    20. PreATP-grasp domain [52439] (1)
      1. PreATP-grasp domain [52440] (2)
        1. D-Alanine ligase N-terminal domain [52452] (1)
          1. D-Ala-D-Ala ligase, N-domain [52453]
            1. Escherichia coli, gene ddlB [52454] (3) picpic
        2. Prokaryotic glutathione synthetase, N-terminal domain [52457] (1)
          1. Prokaryotic glutathione synthetase, N-terminal domain [52458]
            1. Escherichia coli [52459] (4) picpic
    21. DHS-like NAD/FAD-binding domain [52466] (1)
      1. DHS-like NAD/FAD-binding domain [52467] (2)
        1. Deoxyhypusine synthase, DHS [52468] (1)
          1. Deoxyhypusine synthase, DHS [52469]
            1. Human (Homo sapiens) [52470] (1) picpic
        2. Pyruvate oxidase and decarboxylase, middle domain [52475] (1)
          1. Benzoylformate decarboxylase [52482]
            1. Pseudomonas putida [52483] (1) picpic
    22. Tubulin nucleotide-binding domain-like [52489] (1)
      1. Tubulin nucleotide-binding domain-like [52490] (1)
        1. Tubulin, GTPase domain [52491] (1)
          1. Cell-division protein FtsZ [52492]
            1. Archaeon Methanococcus jannaschii [52493] (1) picpic
    23. HAD-like [56783] (1)
      1. HAD-like [56784] (1)
        1. L-2-Haloacid dehalogenase, HAD [56785] (1)
          1. L-2-Haloacid dehalogenase, HAD [56786]
            1. Pseudomonas sp., strain YL [56787] (3) picpic
    24. Thiamin diphosphate-binding fold (THDP-binding) [52517] (1)
      1. Thiamin diphosphate-binding fold (THDP-binding) [52518] (2)
        1. Pyruvate oxidase and decarboxylase Pyr module [88724] (1)
          1. Benzoylformate decarboxylase [88731]
            1. Pseudomonas putida [88732] (1) picpic
        2. Pyruvate oxidase and decarboxylase PP module [88749] (1)
          1. Benzoylformate decarboxylase [88756]
            1. Pseudomonas putida [88757] (1) picpic
    25. P-loop containing nucleoside triphosphate hydrolases [52539] (1)
      1. P-loop containing nucleoside triphosphate hydrolases [52540] (10)
        1. Nucleotide and nucleoside kinases [52541] (8)
          1. Guanylate kinase [52542]
            1. Baker's yeast (Saccharomyces cerevisiae) [52543] (1) picpic
          2. Uridylate kinase [52544]
            1. Baker's yeast (Saccharomyces cerevisiae) [52545] (2) picpic
          3. UMP/CMP kinase [52550]
            1. Dictyostelium discoideum [52551] (4) picpic
          4. Thymidine kinase [52552]
            1. Herpes simplex virus type 1, different strains [52553] (3) picpic
          5. Adenylate kinase [52554]
            1. Pig (Sus scrofa) [52555] (1) picpic
            2. Cow (Bos taurus), mitochondrial izozyme-2 [52558] (2) picpic
            3. Baker's yeast (Saccharomyces cerevisiae) [52559] (3) picpic
            4. Bacillus stearothermophilus [52562] (3) picpic
        2. Phosphoribulokinase/pantothenate kinase [52584] (1)
          1. Phosphoribulokinase [52585]
            1. Rhodobacter sphaeroides [52586] (1) picpic
        3. 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain [52589] (1)
          1. 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain [52590]
            1. Rat (Rattus norvegicus) [52591] (1) picpic
        4. G proteins [52592] (11)
          1. cH-p21 Ras protein [52593]
            1. Human (Homo sapiens) [52594] (24) picpic
          2. Rac [52595]
            1. Human (Homo sapiens) [52596] (1) picpic
          3. Rap2a [52599]
            1. Human (Homo sapiens) [52600] (2) picpic
          4. RhoA [52612]
            1. Human (Homo sapiens) [52613] (2) picpic
          5. ADP-ribosylation factor [52614]
            1. Rat (Rattus norvegicus), ARF1 [52616] (1) picpic
          6. CDC42 [52619]
            1. Human (Homo sapiens) [52620] (1) picpic
          7. Transducin (alpha subunit) [52623]
            1. Cow (Bos taurus) [52624] (1) picpic
            2. Rat (Rattus norvegicus) [52625] (10) picpic
          8. Elongation factor Tu (EF-Tu), N-terminal (G) domain [52626]
            1. Escherichia coli [52627] (2) picpic
            2. Thermus aquaticus [52628] (1) picpic
          9. Elongation factor G (EF-G), N-terminal (G) domain [52633]
            1. Thermus thermophilus [52634] (2) picpic
        5. Motor proteins [52641] (3)
          1. Myosin S1, motor domain [52642]
            1. Slime mold (Dictyostelium discoideum) [52645] (8) picpic
          2. Kinesin [52646]
            1. Human (Homo sapiens) [52647] (1) picpic
          3. Kinesin motor Ncd (non-claret disjunctional) [52649]
            1. Baker's yeast (Saccharomyces cerevisiae), Kar [52651] (1) picpic
        6. Nitrogenase iron protein-like [52652] (4)
          1. Dethiobiotin synthetase [52653]
            1. Escherichia coli [52654] (10) picpic
          2. Adenylosuccinate synthetase, PurA [52655]
            1. Escherichia coli [52656] (7) picpic
          3. GTPase domain of the signal sequence recognition protein Ffh [52664]
            1. Thermus aquaticus [52665] (3) picpic
          4. GTPase domain of the signal recognition particle receptor FtsY [52666]
            1. Escherichia coli [52667] (1) picpic
        7. RecA protein-like (ATPase-domain) [52670] (1)
          1. RecA protein, ATPase-domain [52671]
            1. Escherichia coli [52672] (2) picpic
        8. Tandem AAA-ATPase domain [81268] (1)
          1. DEXX box DNA helicase [52701]
            1. Bacillus stearothermophilus, PcrA [52702] (2) picpic
        9. Extended AAA-ATPase domain [81269] (3)
          1. delta prime subunit of DNA polymerase III, N-domain [52711]
            1. Escherichia coli [52712] (1) picpic
          2. Hexamerization domain of N-ethylmalemide-sensitive fusion (NSF) protein [52717]
            1. Chinese hamster (Cricetulus griseus) [52718] (1) picpic
          3. Replication factor C1 [110566]
            1. Baker's yeast (Saccharomyces cerevisiae) [110567] (1) picpic
        10. RNA helicase [52724] (1)
          1. HCV helicase domain [52725]
            1. Human hepatitis C virus (HCV), different isolates [52726] (2) picpic
    26. PTS IIb component [52727] (1)
      1. PTS IIb component [52728] (1)
        1. PTS IIb component [52729] (1)
          1. Fructose permease, subunit IIb [52730]
            1. Bacillus subtilis [52731] (1) picpic
    27. Methylesterase CheB, C-terminal domain [52737] (1)
      1. Methylesterase CheB, C-terminal domain [52738] (1)
        1. Methylesterase CheB, C-terminal domain [52739] (1)
          1. Methylesterase CheB, C-terminal domain [52740]
            1. Salmonella typhimurium [52741] (1) picpic
    28. Subtilisin-like [52742] (1)
      1. Subtilisin-like [52743] (1)
        1. Subtilases [52744] (9)
          1. Subtilisin [52745]
            1. Bacillus subtilis, carlsberg [52746] (1) picpic
            2. Bacillus licheniformis [52748] (12) picpic
            3. Bacillus lentus, savinase (TM) [52749] (1) picpic
            4. Bacillus lentus [52750] (3) picpic
            5. Bacillus amyloliquefaciens, Novo/BPN' [52751] (20) picpic
          2. M-proteinase [52754]
            1. Bacillus sp., strain ksm-k16 [52755] (1) picpic
          3. Serine protease PB92 (subtilisin PB92) [52756]
            1. Bacillus alcalophilus, Bacillus lentus [52757] (1) picpic
          4. Thermitase [52760]
            1. Thermoactinomyces vulgaris [52761] (1) picpic
          5. Proteinase K [52762]
            1. Fungus (Tritirachium album), strain limber [52763] (3) picpic
    29. CoA-dependent acyltransferases [52776] (1)
      1. CoA-dependent acyltransferases [52777] (1)
        1. CAT-like [52778] (4)
          1. Chloramphenicol acetyltransferase, CAT [52779]
            1. Escherichia coli [52780] (5) picpic
            2. Shigella flexneri [52781] (1) picpic
          2. Dihydrolipoamide acetyltransferase [52782]
            1. Azotobacter vinelandii [52783] (9) picpic
          3. Dihydrolipoamide succinyltransferase [52785]
            1. Escherichia coli [52786] (1) picpic
    30. Phosphotyrosine protein phosphatases I-like [52787] (2)
      1. Phosphotyrosine protein phosphatases I [52788] (1)
        1. Low-molecular-weight phosphotyrosine protein phosphatases [52789] (2)
          1. Tyrosine phosphatase [52790]
            1. Cow (Bos taurus) [52791] (3) picpic
            2. Human (Homo sapiens) [52792] (1) picpic
      2. PTS system, Lactose/Cellobiose specific IIB subunit [52794] (1)
        1. PTS system, Lactose/Cellobiose specific IIB subunit [52795] (1)
          1. Enzyme IIB-cellobiose [52796]
            1. Escherichia coli [52797] (1) picpic
    31. (Phosphotyrosine protein) phosphatases II [52798] (1)
      1. (Phosphotyrosine protein) phosphatases II [52799] (2)
        1. Dual specificity phosphatase-like [52800] (1)
          1. Mapk phosphatase [52803]
            1. Human (Homo sapiens), pyst1 (mkp3) [52804] (1) picpic
        2. Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (3)
          1. Tyrosine phosphatase [52806]
            1. Human (Homo sapiens), 1B [52807] (5) picpic
            2. Human (Homo sapiens), shp-1 [52811] (1) picpic
          2. Protein-tyrosine phosphatase YopH, catalytic domain [100952]
            1. Yersinia enterocolitica [52812] (3) picpic
    32. Rhodanese/Cell cycle control phosphatase [52820] (1)
      1. Rhodanese/Cell cycle control phosphatase [52821] (2)
        1. Cell cycle control phosphatase, catalytic domain [52822] (1)
          1. CDC25a [52823]
            1. Human (Homo sapiens) [52824] (1) picpic
        2. Sulfurtransferase (rhodanese) [52827] (2)
          1. Rhodanese [52828]
            1. Cow (Bos taurus) [52829] (12) picpic
          2. Sulfurtransferase [52830]
            1. Thermus thermophilus [110602] (1) picpic
    33. Thioredoxin fold [52832] (1)
      1. Thioredoxin-like [52833] (5)
        1. Thioltransferase [52834] (9)
          1. Thioredoxin [52835]
            1. Escherichia coli [52836] (4) picpic
            2. Anabaena sp., pcc 7120 [52837] (1) picpic
            3. Chlamydomonas reinhardtii [52838] (1) picpic
            4. Human (Homo sapiens) [52842] (12) picpic
          2. Glutaredoxin (Grx, thioltransferase) [52843]
            1. Bacteriophage T4 [52844] (1) picpic
            2. Escherichia coli [52845] (3) picpic
            3. Escherichia coli, Grx3 [52846] (1) picpic
            4. Pig (Sus scrofa) [52847] (1) picpic
            5. Human (Homo sapiens) [52848] (1) picpic
        2. PDI-like [52849] (2)
          1. Protein disulfide isomerase, PDI [52850]
            1. Human (Homo sapiens) [52851] (2) picpic
            2. Archaeon Pyrococcus furiosus [52852] (2) picpic
        3. Calsequestrin [52855] (1)
          1. Calsequestrin [52856]
            1. Rabbit (Oryctolagus cuniculus) [52857] (3) picpic
        4. DsbA-like [100953] (2)
          1. Disulfide-bond formation facilitator (DsbA) [100954]
            1. Escherichia coli [100955] (3) picpic
            2. Vibrio cholerae [100956] (1) picpic
        5. Glutathione S-transferase (GST), N-terminal domain [52862] (6)
          1. Class mu GST [81359]
            1. Human (Homo sapiens) [52867] (1) picpic
          2. Class alpha GST [81360]
            1. Schistosoma japonicum [52878] (4) picpic
            2. Fasciola hepatica [52879] (1) picpic
          3. Class sigma GST [81362]
            1. Squid (Ommastrephes sloani pacificus) [52876] (2) picpic
          4. Class phi GST [81367]
            1. Maize (Zea mays), type III [52882] (1) picpic
          5. Class beta GST [81368]
            1. Proteus mirabilis [52884] (1) picpic
    34. Pyruvate kinase C-terminal domain-like [52934] (1)
      1. PK C-terminal domain-like [52935] (1)
        1. Pyruvate kinase, C-terminal domain [52936] (2)
          1. Pyruvate kinase, C-terminal domain [52937]
            1. Cat (Felis catus) [52938] (1) picpic
            2. Rabbit (Oryctolagus cuniculus) [52939] (1) picpic
    35. Restriction endonuclease-like [52979] (1)
      1. Restriction endonuclease-like [52980] (3)
        1. Restriction endonuclease BamHI [52987] (1)
          1. Restriction endonuclease BamHI [52988]
            1. Bacillus amyloliquefaciens [52989] (1) picpic
        2. Cfr10I/Bse634I [52999] (1)
          1. Restriction endonuclease Cfr10I [53000]
            1. Citrobacter freundii [53001] (1) picpic
        3. DNA mismatch repair protein MutH from [53020] (1)
          1. DNA mismatch repair protein MutH from [53021]
            1. Escherichia coli [53022] (1) picpic
    36. Resolvase-like [53040] (1)
      1. Resolvase-like [53041] (1)
        1. gamma,delta resolvase, catalytic domain [53042] (1)
          1. gamma,delta resolvase, catalytic domain [53043]
            1. Escherichia coli [53044] (1) picpic
    37. IIA domain of mannose transporter, IIA-Man [53061] (1)
      1. IIA domain of mannose transporter, IIA-Man [53062] (1)
        1. IIA domain of mannose transporter, IIA-Man [53063] (1)
          1. IIA domain of mannose transporter, IIA-Man [53064]
            1. Escherichia coli [53065] (1) picpic
    38. Ribonuclease H-like motif [53066] (4)
      1. Actin-like ATPase domain [53067] (2)
        1. Actin/HSP70 [53068] (1)
          1. Heat shock protein 70kDa, ATPase fragment [53069]
            1. Cow (Bos taurus) [53070] (38) picpic
        2. Hexokinase [53083] (1)
          1. Hexokinase [53084]
            1. Blood fluke (Schistosoma mansoni) [53085] (2) picpic
      2. Creatinase/prolidase N-terminal domain [53092] (1)
        1. Creatinase/prolidase N-terminal domain [53093] (1)
          1. Aminopeptidase P [53096]
            1. Escherichia coli [53097] (2) picpic
      3. Ribonuclease H-like [53098] (4)
        1. Ribonuclease H [53099] (2)
          1. RNase H (RNase HI) [53100]
            1. Escherichia coli [53101] (20) picpic
            2. Thermus thermophilus [53102] (1) picpic
        2. Retroviral integrase, catalytic