Structural Classification of Proteins
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Fold: The spindle assembly checkpoint protein mad2

core: alpha(2)-beta(2)-alpha-beta; mixed sheet: order 213

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: The spindle assembly checkpoint protein mad2 [56018]
    core: alpha(2)-beta(2)-alpha-beta; mixed sheet: order 213

Superfamilies:

  1. The spindle assembly checkpoint protein mad2 [56019] (1)
    N- and C-termini undergo large conformational rearrangement upon ligand binding
    1. The spindle assembly checkpoint protein mad2 [56020] (1)
      1. The spindle assembly checkpoint protein mad2 [56021]
        1. Human (Homo sapiens) [TaxId: 9606] [56022] (4)
          1. 1go4 picpicxref
            complex with mad1
            mutant
            1. chain a [70292] picpiclink
            2. chain b [70293] picpiclink
            3. chain c [70294] picpiclink
            4. chain d [70295] picpiclink
          2. 1s2h picpic
            mutant
            1. chain a [98385] picpiclink
          3. 1klq picpic
            complex with MBP1 peptide
            1. chain a [68689] picpiclink
          4. 1duj picpic
            "apo" form
            1. chain a [41449] picpiclink
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MRC site Generated from scop database 1.73 with scopm 1.101 on Wed Nov 21 11:18:32 2007
Copyright © 1994-2007 The scop authors / scop@mrc-lmb.cam.ac.uk