Structural Classification of Proteins
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Fold: Eukaryotic type KH-domain (KH-domain type I)

beta-alpha(2)-beta(2)-alpha; 2 layers: alpha/beta

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Eukaryotic type KH-domain (KH-domain type I) [54790]
    beta-alpha(2)-beta(2)-alpha; 2 layers: alpha/beta

Superfamilies:

  1. Eukaryotic type KH-domain (KH-domain type I) [54791] (1)
    Prokaryotic and eukaryotic domains share a KH-motif but have different topologies
    1. Eukaryotic type KH-domain (KH-domain type I) [54792] (14)
      an RNA-binding domain
      1. Neuro-oncological ventral antigen 1, nova-1, KH3 [54793]
        1. Human (Homo sapiens) [TaxId: 9606] [54794] (1) picpic
      2. Neuro-oncological ventral antigen 2, nova-2, KH3 [54795]
        1. Human (Homo sapiens) [TaxId: 9606] [54796] (2) picpic
      3. Vigilin [54797]
        1. Human (Homo sapiens) [TaxId: 9606] [54798] (8) picpic
      4. Fragile X protein, KH1 [54799]
        1. Human (Homo sapiens) [TaxId: 9606] [54800] (1) picpic
      5. HnRNP K, KH3 [54801]
        1. Human (Homo sapiens) [TaxId: 9606] [54802] (8) picpic
      6. RNA splicing factor 1 [69699]
        1. Human (Homo sapiens) [TaxId: 9606] [69700] (1) picpic
      7. Far upstream binding element, FBP [75418]
        1. Human (Homo sapiens) [TaxId: 9606] [75419] (1) picpic
        2. Mouse (Mus musculus) [TaxId: 10090] [143219] (2) picpic
      8. Hypothetical protein APE0754 [110927]
        duplication: tandem repeat of two KH-1 domains
        1. Aeropyrum pernix [TaxId: 56636] [110928] (1) picpic
      9. Tudor and KH domain containing protein, Tdrkh [117912]
        1. Mouse (Mus musculus) [TaxId: 10090] [117913] (1) picpic
      10. Poly(RC)-binding protein 2 [143220]
        contains three KH domains
        1. Human (Homo sapiens) [TaxId: 9606] [143221] (12) picpic
      11. Fragile X mental retardation syndrome related protein 1, FXR1 [143222]
        1. Human (Homo sapiens) [TaxId: 9606] [143223] (1) picpic
      12. Poly(RC)-binding protein 1 [143224]
        1. Human (Homo sapiens) [TaxId: 9606] [143225] (1) picpic
      13. Quaking protein A (Xqua) [143226]
        1. African clawed frog (Xenopus laevis) [TaxId: 8355] [143227] (1) picpic
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MRC site Generated from scop database 1.73 with scopm 1.101 on Wed Nov 21 11:18:32 2007
Copyright © 1994-2007 The scop authors / scop@mrc-lmb.cam.ac.uk