Structural Classification of Proteins
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Changes in domain definitions and classification
Release 1.69 ---> 1.71

Root: scop

Classes:

  1. All alpha proteins [46456] (4)
    1. Long alpha-hairpin [46556] (1)
      1. Theta subunit of DNA polymerase III [46575] (1)
        1. Theta subunit of DNA polymerase III [46576] (1)
          1. Theta subunit of DNA polymerase III [46577]
            1. Escherichia coli [46578] (1) picpic
    2. DNA/RNA-binding 3-helical bundle [46688] (1)
      1. Sigma3 and sigma4 domains of RNA polymerase sigma factors [88659] (1)
        1. Sigma4 domain [88665] (1)
          1. Sigma factor SigA [88668]
            1. Thermus aquaticus [88669] (4) picpic
    3. Hypothetical protein Aq 328 [101316] (1)
      1. Hypothetical protein Aq 328 [101317] (1)
        1. Hypothetical protein Aq 328 [101318] (1)
          1. Hypothetical protein Aq 328 [101319]
            1. Aquifex aeolicus [101320] (1) picpic
    4. Porin chaperone SurA, peptide-binding domain [81826] (1)
      1. Porin chaperone SurA, peptide-binding domain [81827] (1)
        1. Porin chaperone SurA, peptide-binding domain [81828] (1)
          1. Porin chaperone SurA, peptide-binding domain [81829]
            1. Escherichia coli [81830] (4) picpic
  2. All beta proteins [48724] (6)
    1. Immunoglobulin-like beta-sandwich [48725] (1)
      1. Immunoglobulin [48726] (1)
        1. V set domains (antibody variable domain-like) [48727] (3)
          1. Immunoglobulin light chain kappa variable domain, VL-kappa [88519]
            1. Human (Homo sapiens), cluster 1 [88520] (1) picpic
            2. Mouse (Mus musculus), cluster 4 [88531] (2) picpic
          2. Immunoglobulin heavy chain variable domain, VH [88543]
            1. Human (Homo sapiens), cluster 1 [88544] (1) picpic
    2. Virus attachment protein globular domain [49834] (1)
      1. Virus attachment protein globular domain [49835] (1)
        1. Reovirus attachment protein sigma 1 head domain [69225] (1)
          1. Reovirus attachment protein sigma 1 head domain [69226]
            1. Reovirus [69227] (3) picpic
    3. OB-fold [50198] (1)
      1. Nucleic acid-binding proteins [50249] (1)
        1. Cold shock DNA-binding domain-like [50282] (2)
          1. Eukaryotic initiation factor 2alpha, eIF2alpha, N-terminal domain [74950]
            1. Human (Homo sapiens) [74951] (2) picpic
            2. Baker's yeast (Saccharomyces cerevisiae) [101764] (1) picpic
    4. Elongation factor/aminomethyltransferase common domain [50464] (1)
      1. Aminomethyltransferase beta-barrel domain [101790] (1)
        1. Aminomethyltransferase beta-barrel domain [101791] (1)
          1. Glycine cleavage system T protein, GcvT [110231]
            1. Escherichia coli [110233] (1) picpic
    5. Double psi beta-barrel [50684] (1)
      1. ADC-like [50692] (1)
        1. Cdc48 N-terminal domain-like [50708] (1)
          1. Peroxisome biogenesis factor 1 (PEX-1), N-terminal domain [110252]
            1. Mouse (Mus musculus) [110253] (1) picpic
    6. Triple beta-spiral [51224] (1)
      1. Fibre shaft of virus attachment proteins [51225] (1)
        1. Reovirus attachment protein sigma 1 [69356] (1)
          1. Reovirus attachment protein sigma 1 [69357]
            1. Reovirus [69358] (3) picpic
  3. Alpha and beta proteins (a/b) [51349] (9)
    Mainly parallel beta sheets (beta-alpha-beta units)
    1. NAD(P)-binding Rossmann-fold domains [51734] (1)
      1. NAD(P)-binding Rossmann-fold domains [51735] (1)
        1. Potassium channel NAD-binding domain [63944] (1)
          1. Potassium channel-related protein MthK [75122]
            1. Archaeon Methanothermobacter thermautotrophicus [75123] (8) picpic
    2. Hypothetical protein PA1492 [110459] (1)
      1. Hypothetical protein PA1492 [110460] (1)
        1. Hypothetical protein PA1492 [110461] (1)
          1. Hypothetical protein PA1492 [110462]
            1. Pseudomonas aeruginosa [110463] (2) picpic
    3. Ribonuclease H-like motif [53066] (1)
      1. Actin-like ATPase domain [53067] (1)
        1. Acetate kinase [53080] (1)
          1. Acetate kinase [53081]
            1. Archaeon Methanosarcina thermophila [53082] (4) picpic
    4. Hypothetical protein TM1506 [110649] (1)
      1. Hypothetical protein TM1506 [110650] (1)
        1. Hypothetical protein TM1506 [110651] (1)
          1. Hypothetical protein TM1506 [110652]
            1. Thermotoga maritima [110653] (1) picpic
    5. S-adenosyl-L-methionine-dependent methyltransferases [53334] (1)
      1. S-adenosyl-L-methionine-dependent methyltransferases [53335] (2)
        1. DNA methylase TaqI [88787] (1)
          1. DNA methylase TaqI [53369]
            1. Thermus aquaticus [53370] (8) picpic
        2. Mycolic acid cyclopropane synthase [69560] (1)
          1. CmaA1 [69561]
            1. Mycobacterium tuberculosis [69562] (1) picpic
    6. Dihydrofolate reductases [53596] (1)
      1. Dihydrofolate reductases [53597] (1)
        1. Dihydrofolate reductases [53598] (1)
          1. Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, DFR domain [53610]
            1. Cryptosporidium hominis [110705] (5) picpic
    7. Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1)
      1. Isocitrate/Isopropylmalate dehydrogenase-like [53659] (1)
        1. Phosphotransacetylase [102663] (1)
          1. Putative phosphotransacetylase SPy1128 [102664]
            1. Streptococcus pyogenes [102665] (2) picpic
    8. ATC-like [53670] (1)
      1. Aspartate/ornithine carbamoyltransferase [53671] (1)
        1. Aspartate/ornithine carbamoyltransferase [53672] (1)
          1. Aspartate carbamoyltransferase catalytic subunit [53673]
            1. Escherichia coli [53674] (4) picpic
    9. Cytidine deaminase-like [53926] (1)
      1. AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC [64197] (1)
        1. AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC [64198] (2)
          1. AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC [64199]
            1. Chicken (Gallus gallus) [64200] (8) picpic
            2. Human (Homo sapiens) [102716] (10) picpic
  4. Alpha and beta proteins (a+b) [53931] (9)
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
    1. Cdc48 domain 2-like [54584] (1)
      1. Cdc48 domain 2-like [54585] (1)
        1. Cdc48 domain 2-like [54586] (1)
          1. Peroxisome biogenesis factor 1 (PEX-1), domain 2 [110874]
            1. Mouse (Mus musculus) [110875] (1) picpic
    2. alpha/beta-Hammerhead [54664] (1)
      1. Nicotinate/Quinolinate PRTase C-terminal domain-like [54675] (1)
        1. Nicotinate phosphoribosyltransferase, C-terminal domain [110910] (1)
          1. Nicotinate phosphoribosyltransferase, C-terminal domain [110911]
            1. Baker's yeast (Saccharomyces cerevisiae) [110912] (4) picpic
    3. Aminomethyltransferase folate-binding domain [103024] (1)
      1. Aminomethyltransferase folate-binding domain [103025] (1)
        1. Aminomethyltransferase folate-binding domain [103026] (1)
          1. Glycine cleavage system T protein, GcvT [111012]
            1. Escherichia coli [111014] (1) picpic
    4. T-fold [55619] (1)
      1. Tetrahydrobiopterin biosynthesis enzymes-like [55620] (1)
        1. Urate oxidase (uricase) [55633] (1)
          1. Urate oxidase (uricase) [55634]
            1. Bacillus sp., strain TB-90 [111089] (3) picpic
    5. Nudix [55810] (1)
      1. Nudix [55811] (1)
        1. NADH pyrophosphatase [103214] (1)
          1. NADH pyrophosphatase [103215]
            1. Escherichia coli [103216] (1) picpic
    6. Thymidylate synthase/dCMP hydroxymethylase [55830] (1)
      1. Thymidylate synthase/dCMP hydroxymethylase [55831] (1)
        1. Thymidylate synthase/dCMP hydroxymethylase [55832] (1)
          1. Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain [55841]
            1. Cryptosporidium hominis [111138] (5) picpic
    7. B3/B4 domain of PheRS, PheT [56036] (1)
      1. B3/B4 domain of PheRS, PheT [56037] (1)
        1. B3/B4 domain of PheRS, PheT [56038] (1)
          1. B3/B4 domain of PheRS, PheT [56039]
            1. Thermus thermophilus (Thermus aquaticus) [56040] (5) picpic
    8. C-type lectin-like [56435] (1)
      1. C-type lectin-like [56436] (1)
        1. C-type lectin domain [56437] (2)
          1. DC-SIGN (dendritic cell-specific ICAM-3 grabbing nonintegrin) [69855]
            1. Human (Homo sapiens) [69856] (6) picpic
          2. E-selectin [56456]
            1. Human (Homo sapiens) [56457] (10) picpic
    9. Putative cell cycle protein MesJ, middle and C-terminal domain [82828] (1)
      1. Putative cell cycle protein MesJ, middle and C-terminal domain [82829] (1)
        1. Putative cell cycle protein MesJ, middle and C-terminal domain [82830] (1)
          1. Putative cell cycle protein MesJ, middle and C-terminal domain [82831]
            1. Escherichia coli [82832] (1) picpic
  5. Multi-domain proteins (alpha and beta) [56572] (1)
    Folds consisting of two or more domains belonging to different classes
    1. ADP ribosyl cyclase-like [56628] (1)
      1. ADP ribosyl cyclase-like [56629] (1)
        1. ADP ribosyl cyclase-like [56630] (2)
          1. ADP ribosyl cyclase [56631]
            1. Sea hare (Aplysia californica) [56632] (16) picpic
          2. Bone marror stromal cell antigen 1, BST-1/CD157 (ADP ribosyl cyclase-2) [75597]
            1. Human (Homo sapiens) [75598] (12) picpic
  6. Membrane and cell surface proteins and peptides [56835] (0)
    Does not include proteins in the immune system
  7. Small proteins [56992] (0)
    Usually dominated by metal ligand, heme, and/or disulfide bridges
  8. Coiled coil proteins [57942] (1)
    Not a true class
    1. Antiparallel coiled-coil [58086] (2)
      1. Arfaptin, Rac-binding fragment [64598] (1)
        1. Arfaptin, Rac-binding fragment [64599] (1)
          1. Arfaptin, Rac-binding fragment [64600]
            1. Human (Homo sapiens) [64601] (8) picpic
      2. BAR domain [103657] (1)
        1. BAR domain [103658] (1)
          1. Amphiphysin [103659]
            1. Fruit fly (Drosophila melanogaster) [103660] (1) picpic
  9. Low resolution protein structures [58117] (0)
    Not a true class
  10. Peptides [58231] (0)
    Peptides and fragments. Not a true class
  11. Designed proteins [58788] (0)
    Experimental structures of proteins with essentially non-natural sequences. Not a true class
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MRC site Generated from scop database 1.69_1.71 history with scopm 1.101 on Fri Oct 20 14:13:34 2006
Copyright © 1994-2005 The scop authors / scop@mrc-lmb.cam.ac.uk