Structural Classification of Proteins




Changes in domain definitions and classification
Release 1.65 ---> 1.67Root: scop
Classes:
- All alpha proteins [46456] (11)
- DNA/RNA-binding 3-helical bundle [46688] (2)

- Ferritin-like [47239] (1)

- Bromodomain-like [47363] (1)

- SinR repressor dimerisation domain-like [47405] (1)

- Met repressor-like [47597] (1)

- Disulphide-bond formation facilitator (DSBA), insertion domain [47609] (1)

- 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1)

- FIS-like [48282] (1)

- alpha-alpha superhelix [48370] (2)

- GroEL equatorial domain-like [48591] (1)

- Non-globular all-alpha subunits of globular proteins [48661] (1)

- All beta proteins [48724] (5)
- Viral protein domain [49817] (1)

- Concanavalin A-like lectins/glucanases [49898] (1)

- OB-fold [50198] (1)

- beta-Roll [51119] (1)

- Double-stranded beta-helix [51181] (1)

- Alpha and beta proteins (a/b) [51349] (12)
Mainly parallel beta sheets (beta-alpha-beta units)
- NAD(P)-binding Rossmann-fold domains [51734] (1)

- The "swivelling" beta/beta/alpha domain [52008] (1)

- Outer arm dynein light chain 1 [52074] (1)

- Flavodoxin-like [52171] (2)

- Cysteine hydrolase [52498] (1)

- Phosphosugar isomerase [52511] (1)

- Thiamin diphosphate-binding fold (THDP-binding) [52517] (1)

- (Phosphotyrosine protein) phosphatases II [52798] (1)

- Thioredoxin fold [52832] (1)

- Phosphoglycerate mutase-like [53253] (1)

- CoA transferase [53315] (1)

- Nucleotide-diphospho-sugar transferases [53447] (1)

- Alpha and beta proteins (a+b) [53931] (6)
Mainly antiparallel beta sheets (segregated alpha and beta regions)
- beta-Grasp (ubiquitin-like) [54235] (1)

- GroEL-intermediate domain like [54848] (1)

- Ferredoxin-like [54861] (1)

- DCoH-like [55247] (1)

- SH2-like [55549] (1)

- Thymidylate synthase/dCMP hydroxymethylase [55830] (1)

- Multi-domain proteins (alpha and beta) [56572] (5)
Folds consisting of two or more domains belonging to different classes
- DNA/RNA polymerases [56671] (1)

- beta and beta-prime subunits of DNA dependent RNA-polymerase [64483] (1)

- DNA primase [56746] (1)

- Ku heterodimer subunits [64500] (1)

- Heat shock protein 70kD (HSP70), C-terminal substrate-binding fragment [56777] (1)

- Membrane and cell surface proteins and peptides [56835] (0)
Does not include proteins in the immune system
- Small proteins [56992] (3)
Usually dominated by metal ligand, heme, and/or disulfide bridges
- Ovomucoid/PCI-1 like inhibitors [57466] (1)

- Serine proteinase inhibitor lekti [69958] (1)

- Zinc-binding domain of translation initiation factor 2 beta [75688] (1)

- Coiled coil proteins [57942] (0)
Not a true class
- Low resolution protein structures [58117] (0)
Not a true class
- Peptides [58231] (6)
Peptides and fragments. Not a true class
- Antimicrobial beta-hairpin [58251] (1)

- Antimicrobial helix [58268] (1)

- Arg-rich RNA binding peptides [58321] (1)

- Transmembrane helical fragments [58517] (1)

- MoMLV p15 fragment (residues 409-426) [58624] (1)

- Integrin fragments [58697] (1)

- Designed proteins [58788] (3)
Experimental structures of proteins with essentially non-natural sequences. Not a true class
- Collagen-like peptides [58805] (1)

- VaLd trimeric coiled-coil [58817] (1)

- Designed trimeric coiled-coil peptide [64664] (1)

Generated from scop database 1.65_1.67 history with scopm 1.100 on Mon Feb 7 15:33:01 2005
Copyright
© 1994-2005 The scop authors /
scop@mrc-lmb.cam.ac.uk