Fold: Immunoglobulin-like beta-sandwich

sandwich; 7 strands in 2 sheets; greek-key
some members of the fold have additional strands

Lineage:

1. Root: scop
2. Class: All beta proteins
3. Fold: Immunoglobulin-like beta-sandwich
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

Superfamilies:

1. Immunoglobulin (4)
2. E set domains (17)
   "Early" Ig-like fold families possibly related to the immunoglobulin and/or fibronectin type III superfamilies
3. Fibronectin type III (1)
4. PKD domain (1)
5. beta-Galactosidase/glucuronidase domain (1)
6. Transglutaminase, two C-terminal domains (1)
7. Cadherin (1)
8. Actinoxanthin-like (1)
9. Cu,Zn superoxide dismutase-like (1)
   has additional strand at N-terminus
10. CBD9-like (2)
    has additional strand at N-terminus; the active site in a similar topological location as the Cu,Zn SOD site
11. Lamin A/C globular tail domain (1)
12. Clathrin adaptor appendage domain (2)
    contains an additional N-terminal strand
13. Integrin domains (1)
14. PapD-like (2)
    contains PP switch between strands D and C'
15. Purple acid phosphatase, N-terminal domain (1)
16. Superoxide reductase-like (1)
17. Thiol:disulfide interchange protein DsbD, N-terminal domain (1)
18. Invasin/intimin cell-adhesion fragments (1)
19. Antigen MPT63/MPB63 (immunoprotective extracellular protein) (1)
20. Tp47 lipoprotein, middle and C-terminal domains (1)