Welcome to SCOP: Structural Classification of Proteins.
1.63 release (May 2003).
18946 PDB Entries (1 Mar 2003). 28 Literature References.
49497 Domains
(excluding nucleic acids and theoretical models).
Folds, superfamilies, and families statistics here.
New folds
superfamilies
families.
List of obsolete entries since 1.55.
Authors. Alexey G. Murzin, Loredana Lo Conte, Antonina Andreeva, Dave Howorth, Bartlett G. Ailey,
Steven E. Brenner, Tim J. P. Hubbard, and Cyrus Chothia.
scop@mrc-lmb.cam.ac.uk
Reference:
Murzin A. G., Brenner S. E., Hubbard T., Chothia C. (1995).
SCOP: a structural classification
of proteins database for the investigation of sequences and
structures. J. Mol. Biol. 247, 536-540. [PDF]
Major changes introduced in SCOP 1.55 are described in:
Lo Conte L., Brenner S. E., Hubbard T.J.P., Chothia C., Murzin A. (2002). SCOP database in 2002: refinements accommodate
structural genomics. Nucl. Acid Res. 30(1), 264-267. [PDF].
Copyright: SCOP is
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SCOP mirrors around the world may speed your access.
icon. There are also some new options,
such as a structural similarity search of the SCOP database
using SSM.
If you think your work is of interest for our users, please
get in touch with us.
Nearly all proteins have structural similarities with other proteins and, in some of these cases, share a common evolutionary origin. The SCOP database, created by manual inspection and abetted by a battery of automated methods, aims to provide a detailed and comprehensive description of the structural and evolutionary relationships between all proteins whose structure is known. As such, it provides a broad survey of all known protein folds, detailed information about the close relatives of any particular protein, and a framework for future research and classification.
A more detailed description of the database is available. Help on using the database may be obtained on any screen by pressing the question mark button.