Class: Designed proteins

Experimental structures of proteins with essentially non-natural sequences. Not a true class

Lineage:

1. Root: scop
2. Class: Designed proteins
   Experimental structures of proteins with essentially non-natural sequences. Not a true class

Folds:

1. Hybrid and chimeric proteins (1)
2. Amphiphilic (amphipathic) alpha helix (1)
3. Collagen-like peptides (1)
4. Alpha helical bundle (1)
5. Alpha helical bundle (1)
6. Designed trimeric coiled-coil peptide (1)
7. Designed heterodimeric leucine zipper (1)
8. Thermostable heterotrimeric coiled coil (1)
9. Designed four helix bundle protein (1)
10. Designed single chain three-helix bundle (1)
    not a true fold: both possible topologies are created
11. Peptide f (amphiphilic octadecapeptide) (1)
12. Retro-GCN4 leucine zipper (1)
13. Glytm1bzip (1)
14. Zinc finger design (1)
15. Protein A Ig(Fc)-binding domain mimics (1)
16. Zinc finger based beta-beta-alpha motif (1)
17. Alpha-t-alpha, a de novo designed peptide (1)
18. alpha2d (1)
19. RH4 designed right-handed coiled coil tetramer (1)
20. Erythropoietin (EPO) mimetic peptides (1)
21. IL-1 receptor type 1 antagonist peptide AF10847 (1)
22. Octreotide (Sandostatine), a somatostatine analogue (1)
23. Calmodulin (1)
24. Prototype WW domain (1)
25. Scorpion toxin-based designs (1)
26. TH (toxin hand)-motif beta-sheet mini-protein designs (1)
27. Inhibitor of mammalian ribonucleotide reductase (1)
28. Integrin-binding RGD peptide (1)
29. Peptide antagonists of IGF-1 (1)
30. beta-hairpin design (1)
31. Trp-cage miniprotein (1)
32. Synthetic high affinity IgE receptor antagonists (1)
33. IFN mimetic syr6 (1)
34. TAZ (CH) Zn-binding domain based design (1)
35. Beta-sheet designs (1)
36. PW2, atryptophan-rich anticocidial peptide (1)