Structural Classification of Proteins
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Changes in domain definitions and classification
Release 1.57 ---> 1.59

Root: scop

Classes:

  1. All alpha proteins [46456] (5)
    1. DNA/RNA-binding 3-helical bundle [46688] (1)
      1. Homeodomain-like [46689] (1)
        1. Paired domain [46748] (1)
          1. Pax-6 [46749]
            1. Human (Homo sapiens) [46750] (1) picpic
    2. Histone-fold [47112] (1)
      1. Histone-fold [47113] (1)
        1. Archaeal histone [47129] (2)
          1. Histone A [47130]
            1. Methanothermus fervidus [47131] (3) picpic
          2. Histone B [47132]
            1. Methanothermus fervidus [47133] (4) picpic
    3. Four-helical up-and-down bundle [47161] (1)
      1. Acyl-CoA dehydrogenase (flavoprotein), C-terminal domain [47203] (1)
        1. Acyl-CoA dehydrogenase (flavoprotein), C-terminal domain [47204] (4)
          1. Butyryl-CoA dehydrogenase [47205]
            1. Megasphaera elsdenii [47206] (2) picpic
          2. Medium chain acyl-CoA dehydrogenase [47207]
            1. Pig (Sus scrofa) [47208] (4) picpic
            2. Human (Homo sapiens) [47209] (12) picpic
          3. Isovaleryl-CoA dehydrogenase [47210]
            1. Human (Homo sapiens) [47211] (4) picpic
    4. Bromodomain-like [47363] (1)
      1. Domain of the SRP/SRP receptor G-proteins [47364] (1)
        1. Domain of the SRP/SRP receptor G-proteins [47365] (3)
          1. Signal sequence recognition protein Ffh [47366]
            1. Thermus aquaticus [47367] (8) picpic
            2. Archaeon Acidianus ambivalens [63538] (2) picpic
          2. Signal recognition particle receptor, FtsY [47368]
            1. Escherichia coli [47369] (1) picpic
    5. EF Hand-like [47472] (1)
      1. EF-hand [47473] (1)
        1. Calmodulin-like [47502] (1)
          1. Calcium vector protein [63539]
            1. Amphioxus (Branchiostoma lanceolatum) [63540] (2) picpic
  2. All beta proteins [48724] (5)
    1. Immunoglobulin-like beta-sandwich [48725] (1)
      1. Immunoglobulin [48726] (3)
        1. V set domains (antibody variable domain-like) [48727] (1)
          1. Immunoglobulin (variable domains of L and H chains) [48749]
            1. Bactericidal Fab (mouse), kappa L chain [48826] (2) picpic
        2. C1 set domains (antibody constant domain-like) [48942] (1)
          1. Immunoglobulin (constant domains of L and H chains) [48972]
            1. Bactericidal Fab (mouse), kappa L chain [49042] (2) picpic
        3. E set domains [49208] (2)
          1. Cellulosomal scaffoldin protein CipC, module x2.1 [49263]
            1. Clostridium cellulolyticum [49264] (1) picpic
          2. Cytomegalovirus protein US2 [63668]
            1. Human cytomegalovirus [63669] (4) picpic
    2. Concanavalin A-like lectins/glucanases [49898] (1)
      1. Concanavalin A-like lectins/glucanases [49899] (1)
        1. Endoglucanase/cellulase I catalitic core [49971] (4)
          1. Cellobiohydrolase I (cellulase), CBH1, Cel7A [49972]
            1. Trichoderma reesei [49973] (12) picpic
          2. Endoglucanase I [49974]
            1. Trichoderma reesei [49975] (2) picpic
            2. Fusarium oxysporum [49976] (12) picpic
            3. Humicola insolens, cel7b [49977] (4) picpic
    3. PDZ domain-like [50155] (1)
      1. PDZ domain-like [50156] (1)
        1. PDZ domain [50157] (1)
          1. Photosystem II D1 C-terminal processing protease, PDZ domain [50170]
            1. Algae (Scenedesmus obliquus) [50171] (4) picpic
    4. OB-fold [50198] (1)
      1. Nucleic acid-binding proteins [50249] (1)
        1. Cold shock DNA-binding domain-like [50282] (1)
          1. Rho termination factor, N-terminal, RNA-binding domain [50294]
            1. Escherichia coli [50295] (7) picpic
    5. beta-clip [51268] (1)
      1. Molybdenum cofactor biosynthesis protein MoeA, C-terminal domain [63867] (1)
        1. Molybdenum cofactor biosynthesis protein MoeA, C-terminal domain [63868] (1)
          1. Molybdenum cofactor biosynthesis protein MoeA, C-terminal domain [63869]
            1. Escherichia coli [63870] (6) picpic
  3. Alpha and beta proteins (a/b) [51349] (9)
    Mainly parallel beta sheets (beta-alpha-beta units)
    1. TIM beta/alpha-barrel [51350] (1)
      1. (Trans)glycosidases [51445] (1)
        1. beta-glycanases [51487] (1)
          1. Exo-beta-(1,3)-glucanase [51505]
            1. Yeast (Candida albicans) [51506] (1) picpic
    2. ClpP/crotonase [52095] (1)
      1. ClpP/crotonase [52096] (1)
        1. Photosystem II D1 C-terminal processing protease, catalytic domain [52100] (1)
          1. Photosystem II D1 C-terminal processing protease, catalytic domain [52101]
            1. Algae (Scenedesmus obliquus) [52102] (4) picpic
    3. P-loop containing nucleotide triphosphate hydrolases [52539] (1)
      1. P-loop containing nucleotide triphosphate hydrolases [52540] (1)
        1. G proteins [52592] (1)
          1. Elongation factor Tu (EF-Tu), N-terminal (G) domain [52626]
            1. Escherichia coli [52627] (2) picpic
    4. Thioredoxin fold [52832] (1)
      1. Thioredoxin-like 2Fe-2S ferredoxin [52917] (1)
        1. Thioredoxin-like 2Fe-2S ferredoxin [52918] (1)
          1. Thioredoxin-like 2Fe-2S ferredoxin [52919]
            1. Aquifex aeolicus [52920] (2) picpic
    5. Ribonuclease H-like motif [53066] (1)
      1. Actin-like ATPase domain [53067] (1)
        1. Hexokinase [53083] (1)
          1. Hexokinase [53084]
            1. Baker's yeast (Saccharomyces cerevisiae), pII [64092] (1) picpic
    6. Molybdenum cofactor biosynthesis proteins [53217] (1)
      1. Molybdenum cofactor biosynthesis proteins [53218] (1)
        1. MoeA, central domain [64103] (1)
          1. MoeA, central domain [64104]
            1. Escherichia coli [64105] (6) picpic
    7. S-adenosyl-L-methionine-dependent methyltransferases [53334] (1)
      1. S-adenosyl-L-methionine-dependent methyltransferases [53335] (1)
        1. Protein-L-isoaspartate O-methyltransferase [53354] (1)
          1. Protein-L-isoaspartate O-methyltransferase [53355]
            1. Thermotoga maritima [53356] (2) picpic
    8. Nucleotide-diphospho-sugar transferases [53447] (1)
      1. Nucleotide-diphospho-sugar transferases [53448] (2)
        1. 4-diphosphocytidyl-2-c-methylerythritol (CDP-me) synthase (YgbP) [64139] (1)
          1. 4-diphosphocytidyl-2-c-methylerythritol (CDP-me) synthase (YgbP) [64140]
            1. Escherichia coli [64141] (2) picpic
        2. CMP:2-keto-3-deoxy-manno-octonic acid (CMP-KDO)synthetase, KdsB [64142] (1)
          1. CMP:2-keto-3-deoxy-manno-octonic acid (CMP-KDO)synthetase, KdsB [64143]
            1. Escherichia coli [64144] (12) picpic
    9. PEP carboxykinase-like [53794] (1)
      1. PEP carboxykinase-like [53795] (1)
        1. Phosphoenolpyruvate (PEP) carboxykinase (ATP-oxaloacetate carboxy-liase) [53796] (1)
          1. Phosphoenolpyruvate (PEP) carboxykinase (ATP-oxaloacetate carboxy-liase) [53797]
            1. Escherichia coli [53798] (3) picpic
  4. Alpha and beta proteins (a+b) [53931] (3)
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
    1. His-Me finger endonucleases [54059] (1)
      1. His-Me finger endonucleases [54060] (1)
        1. Recombination endonuclease VII [54072] (1)
          1. Recombination endonuclease VII [54073]
            1. Bacteriophage T4 [54074] (6) picpic
    2. KH-domain [54790] (1)
      1. KH-domain [54791] (1)
        1. KH-domain [54792] (1)
          1. Polynucleotide phosphorylase/guanosine pentaphospate synthase (PNPase/GPSI), domain 6 [54803]
            1. Streptomyces antibioticus [54804] (2) picpic
    3. Fibrinogen C-terminal domains [56495] (1)
      1. Fibrinogen C-terminal domains [56496] (1)
        1. Fibrinogen C-terminal domains [56497] (1)
          1. Fibrinogen C-terminal domains [56498]
            1. Human (Homo sapiens), beta and gamma [56499] (30) picpic
  5. Multi-domain proteins (alpha and beta) [56572] (2)
    Folds consisting of two or more domains belonging to different classes
    1. Ku heterodimer subunits [64500] (1)
      1. Ku heterodimer subunits [64501] (1)
        1. Ku70 subunit [64502] (1)
          1. Ku70 subunit [64503]
            1. Human (Homo sapiens) [64504] (2) picpic
    2. HAD-like [56783] (1)
      1. HAD-like [56784] (4)
        1. L-2-Haloacid dehalogenase, HAD [56785] (2)
          1. L-2-Haloacid dehalogenase, HAD [56786]
            1. Pseudomonas sp., strain YL [56787] (4) picpic
            2. Xanthobacter autotrophicus [56788] (8) picpic
        2. Epoxide hydrolase, N-terminal domain [56789] (1)
          1. Epoxide hydrolase, N-terminal domain [56790]
            1. Mouse (Mus musculus) [56791] (8) picpic
        3. Phosphonoacetaldehyde hydrolase [56792] (1)
          1. Phosphonoacetaldehyde hydrolase [56793]
            1. Bacillus cereus [56794] (4) picpic
        4. Phosphoserine phosphatase [64511] (1)
          1. Phosphoserine phosphatase [64512]
            1. Archaeon Methanococcus jannaschii [64513] (4) picpic
  6. Membrane and cell surface proteins and peptides [56835] (0)
    Does not include proteins in the immune system
  7. Small proteins [56992] (0)
    Usually dominated by metal ligand, heme, and/or disulfide bridges
  8. Coiled coil proteins [57942] (0)
    Not a true class
  9. Low resolution protein structures [58117] (0)
    Not a true class
  10. Peptides [58231] (0)
    Peptides and fragments. Not a true class
  11. Designed proteins [58788] (0)
    Experimental structures of proteins with essentially non-natural sequences. Not a true class
  12. Non-protein [0] (0)
    PDB entries which are theoretical models, nucleic acids, or other non-proteins

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Generated from scop database 1.57_1.59 history with scopm 1.100 on Mon Jan 26 17:21:24 2004
Copyright © 1994-2003 The scop authors / scop@mrc-lmb.cam.ac.uk