Structural Classification of Proteins
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Changes in domain definitions and classification
Release 1.57 ---> 1.59

Root: scop

Classes:

  1. All alpha proteins [46456] (5)
    1. DNA/RNA-binding 3-helical bundle [46688] (1)
      1. Homeodomain-like [46689] (1)
        1. Paired domain [46748] (1)
          1. Pax-6 [46749]
            1. Human (Homo sapiens) [46750] (1)
              1. 6pax picpic
                cl=same,cf=same,sf=same,fa=same,dm=68936,sp=same,px=64758
                cl=same,cf=same,sf=same,fa=same,dm=68936,sp=same,px=64759
                modified domain definition: A: -> A:1-68 [64758]; A:69-133 [64759]
                1. chain a [16046] picpic
    2. Histone-fold [47112] (1)
      1. Histone-fold [47113] (1)
        1. Archaeal histone [47129] (2)
          1. Histone A [47130]
            1. Methanothermus fervidus [47131] (3)
              1. 1b67 picpic
                cl=same,cf=same,sf=same,fa=same,dm=68897,sp=68895,px=same
                1. chain a [16474] picpic
              2. 1b67 picpic
                cl=same,cf=same,sf=same,fa=same,dm=68897,sp=68895,px=same
                1. chain b [16475] picpic
              3. 1hta picpic
                cl=same,cf=same,sf=same,fa=same,dm=68897,sp=68895,px=same
          2. Histone B [47132]
            1. Methanothermus fervidus [47133] (4)
              1. 1a7w picpic
                cl=same,cf=same,sf=same,fa=same,dm=68897,sp=68896,px=same
              2. 1b6w picpic
                cl=same,cf=same,sf=same,fa=same,dm=68897,sp=68896,px=same
                1. chain a [16478] picpic
              3. 1bfm picpic
                cl=same,cf=same,sf=same,fa=same,dm=68897,sp=68896,px=same
                1. chain a [16479] picpic
              4. 1bfm picpic
                cl=same,cf=same,sf=same,fa=same,dm=68897,sp=68896,px=same
                1. chain b [16480] picpic
    3. Four-helical up-and-down bundle [47161] (1)
      1. Acyl-CoA dehydrogenase (flavoprotein), C-terminal domain [47203] (1)
        1. Acyl-CoA dehydrogenase (flavoprotein), C-terminal domain [47204] (4)
          1. Butyryl-CoA dehydrogenase [47205]
            1. Megasphaera elsdenii [47206] (2)
              1. 1buc picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region a:233-383 [16590] picpic
              2. 1buc picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region b:233-383 [16591] picpic
          2. Medium chain acyl-CoA dehydrogenase [47207]
            1. Pig (Sus scrofa) [47208] (4)
              1. 3mdd picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region a:242-395 [16592] picpic
              2. 3mdd picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region b:242-395 [16593] picpic
              3. 3mde picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region a:242-395 [16594] picpic
              4. 3mde picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region b:242-395 [16595] picpic
            2. Human (Homo sapiens) [47209] (12)
              1. 1egc picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region a:242-396 [16600] picpic
              2. 1egc picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region b:242-396 [16601] picpic
              3. 1egc picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region c:242-396 [16602] picpic
              4. 1egc picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region d:242-396 [16603] picpic
              5. 1egd picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region a:242-396 [16596] picpic
              6. 1egd picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region b:242-396 [16597] picpic
              7. 1egd picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region c:242-396 [16598] picpic
              8. 1egd picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region d:242-396 [16599] picpic
              9. 1ege picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region a:242-396 [16604] picpic
              10. 1ege picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region b:242-396 [16605] picpic
              11. 1ege picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region c:242-396 [16606] picpic
              12. 1ege picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region d:242-396 [16607] picpic
          3. Isovaleryl-CoA dehydrogenase [47210]
            1. Human (Homo sapiens) [47211] (4)
              1. 1ivh picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region a:242-392 [16608] picpic
              2. 1ivh picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region b:242-392 [16609] picpic
              3. 1ivh picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region c:242-392 [16610] picpic
              4. 1ivh picpic
                cl=same,cf=47363,sf=same,fa=same,dm=same,sp=same,px=same
                1. region d:242-392 [16611] picpic
    4. Bromodomain-like [47363] (1)
      1. Domain of the SRP/SRP receptor G-proteins [47364] (1)
        1. Domain of the SRP/SRP receptor G-proteins [47365] (3)
          1. Signal sequence recognition protein Ffh [47366]
            1. Thermus aquaticus [47367] (8)
              1. 1ffh picpic
                cl=same,cf=47161,sf=same,fa=same,dm=same,sp=same,px=same
                1. region 2-88 [16960] picpic
              2. 1ng1 picpic
                cl=same,cf=47161,sf=same,fa=same,dm=same,sp=same,px=same
                1. region 1-88 [16961] picpic
              3. 2ffh picpic
                cl=same,cf=47161,sf=same,fa=same,dm=same,sp=same,px=same
                1. region a:1-88 [16965] picpic
              4. 2ffh picpic
                cl=same,cf=47161,sf=same,fa=same,dm=same,sp=same,px=same
                1. region b:1-88 [16966] picpic
              5. 2ffh picpic
                cl=same,cf=47161,sf=same,fa=same,dm=same,sp=same,px=same
                1. region c:1-88 [16967] picpic
              6. 2ng1 picpic
                cl=same,cf=47161,sf=same,fa=same,dm=same,sp=same,px=same
                1. region 2-88 [16962] picpic
              7. 3ng1 picpic
                cl=same,cf=47161,sf=same,fa=same,dm=same,sp=same,px=same
                1. region a:1-88 [16963] picpic
              8. 3ng1 picpic
                cl=same,cf=47161,sf=same,fa=same,dm=same,sp=same,px=same
                1. region b:1-88 [16964] picpic
            2. Archaeon Acidianus ambivalens [63538] (2)
              1. 1j8m picpic
                cl=same,cf=47161,sf=same,fa=same,dm=same,sp=same,px=same
                1. region f:3-86 [62742] picpic
              2. 1j8y picpic
                cl=same,cf=47161,sf=same,fa=same,dm=same,sp=same,px=same
                1. region f:3-86 [62747] picpic
          2. Signal recognition particle receptor, FtsY [47368]
            1. Escherichia coli [47369] (1)
              1. 1fts picpic
                cl=same,cf=47161,sf=same,fa=same,dm=same,sp=same,px=same
                1. region 201-284 [16968] picpic
    5. EF Hand-like [47472] (1)
      1. EF-hand [47473] (1)
        1. Calmodulin-like [47502] (1)
          1. Calcium vector protein [63539]
            1. Amphioxus (Branchiostoma lanceolatum) [63540] (2)
              1. 1j7q picpic
                cl=same,cf=same,sf=same,fa=same,dm=47514,sp=47515,px=same
                1. chain a [62700] picpic
              2. 1j7r picpic
                cl=same,cf=same,sf=same,fa=same,dm=47514,sp=47515,px=same
                1. chain a [62701] picpic
  2. All beta proteins [48724] (5)
    1. Immunoglobulin-like beta-sandwich [48725] (1)
      1. Immunoglobulin [48726] (3)
        1. V set domains (antibody variable domain-like) [48727] (1)
          1. Immunoglobulin (variable domains of L and H chains) [48749]
            1. Bactericidal Fab (mouse), kappa L chain [48826] (2)
              1. 1mpa picpicxrefxref
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=48874,px=same
                1. region l:1-112 [20134] picpic
              2. 1mpa picpicxrefxref
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=48874,px=same
                1. region h:1-121 [20135] picpic
        2. C1 set domains (antibody constant domain-like) [48942] (1)
          1. Immunoglobulin (constant domains of L and H chains) [48972]
            1. Bactericidal Fab (mouse), kappa L chain [49042] (2)
              1. 1mpa picpicxrefxref
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=49084,px=same
                1. region l:113-219 [21164] picpic
              2. 1mpa picpicxrefxref
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=49084,px=same
                1. region h:122-225 [21165] picpic
        3. E set domains [49208] (2)
          1. Cellulosomal scaffoldin protein CipC, module x2.1 [49263]
            1. Clostridium cellulolyticum [49264] (1)
              1. 1ehx picpic
                cl=same,cf=same,sf=same,fa=68902,dm=same,sp=same,px=same
                1. chain a [21950] picpic
          2. Cytomegalovirus protein US2 [63668]
            1. Human cytomegalovirus [63669] (4)
              1. 1im3 picpic
                cl=same,cf=same,sf=same,fa=68902,dm=same,sp=same,px=same
                1. chain d [62568] picpic
              2. 1im3 picpic
                cl=same,cf=same,sf=same,fa=68902,dm=same,sp=same,px=same
                1. chain h [62572] picpic
              3. 1im3 picpic
                cl=same,cf=same,sf=same,fa=68902,dm=same,sp=same,px=same
                1. chain l [62576] picpic
              4. 1im3 picpic
                cl=same,cf=same,sf=same,fa=68902,dm=same,sp=same,px=same
                1. chain p [62580] picpic
    2. Concanavalin A-like lectins/glucanases [49898] (1)
      1. Concanavalin A-like lectins/glucanases [49899] (1)
        1. Endoglucanase/cellulase I catalitic core [49971] (4)
          1. Cellobiohydrolase I (cellulase), CBH1, Cel7A [49972]
            1. Trichoderma reesei [49973] (12)
              1. 1cel picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=68898,px=same
                1. chain a [24280] picpic
              2. 1cel picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=68898,px=same
                1. chain b [24281] picpic
              3. 1dy4 picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=68898,px=same
                1. chain a [24283] picpic
              4. 1egn picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=68898,px=same
                1. chain a [59411] picpic
              5. 2cel picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=68898,px=same
                1. chain a [24285] picpic
              6. 2cel picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=68898,px=same
                1. chain b [24286] picpic
              7. 3cel picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=68898,px=same
              8. 4cel picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=68898,px=same
                1. chain a [24288] picpic
              9. 4cel picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=68898,px=same
                1. chain b [24289] picpic
              10. 5cel picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=68898,px=same
              11. 6cel picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=68898,px=same
              12. 7cel picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=68898,px=same
          2. Endoglucanase I [49974]
            1. Trichoderma reesei [49975] (2)
              1. 1eg1 picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=68899,px=same
                1. chain a [24290] picpic
              2. 1eg1 picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=68899,px=same
                1. chain c [24291] picpic
            2. Fusarium oxysporum [49976] (12)
              1. 1ovw picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=same,px=same
                1. chain a [24300] picpic
              2. 1ovw picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=same,px=same
                1. chain b [24301] picpic
              3. 1ovw picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=same,px=same
                1. chain c [24302] picpic
              4. 1ovw picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=same,px=same
                1. chain d [24303] picpic
              5. 2ovw picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=same,px=same
                1. chain a [24296] picpic
              6. 2ovw picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=same,px=same
                1. chain b [24297] picpic
              7. 2ovw picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=same,px=same
                1. chain c [24298] picpic
              8. 2ovw picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=same,px=same
                1. chain d [24299] picpic
              9. 3ovw picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=same,px=same
                1. chain a [24292] picpic
              10. 3ovw picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=same,px=same
                1. chain b [24293] picpic
              11. 4ovw picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=same,px=same
                1. chain a [24294] picpic
              12. 4ovw picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=same,px=same
                1. chain b [24295] picpic
            3. Humicola insolens, cel7b [49977] (4)
              1. 1a39 picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=same,px=same
              2. 1dym picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=same,px=same
                1. chain a [24304] picpic
              3. 2a39 picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=same,px=same
                1. chain a [24306] picpic
              4. 2a39 picpic
                cl=same,cf=same,sf=same,fa=same,dm=68900,sp=same,px=same
                1. chain b [24307] picpic
    3. PDZ domain-like [50155] (1)
      1. PDZ domain-like [50156] (1)
        1. PDZ domain [50157] (1)
          1. Photosystem II D1 C-terminal processing protease, PDZ domain [50170]
            1. Algae (Scenedesmus obliquus) [50171] (4)
              1. 1fc6 picpicxref
                cl=same,cf=same,sf=same,fa=68933,dm=68934,sp=same,px=64738
                cl=51349,cf=52095,sf=52096,fa=52100,dm=68935,sp=52102,px=64739
                modified domain definition: A:78-252 -> A:78-156,A:249-463 [64739]; A:157-248 [64738]
                1. region a:78-252 [24783] picpic
              2. 1fc7 picpicxref
                cl=same,cf=same,sf=same,fa=68933,dm=68934,sp=same,px=64740
                cl=51349,cf=52095,sf=52096,fa=52100,dm=68935,sp=52102,px=64741
                modified domain definition: A:78-252 -> A:78-156,A:249-463 [64741]; A:157-248 [64740]
                1. region a:78-252 [24784] picpic
              3. 1fc9 picpicxref
                cl=same,cf=same,sf=same,fa=68933,dm=68934,sp=same,px=64742
                cl=51349,cf=52095,sf=52096,fa=52100,dm=68935,sp=52102,px=64743
                modified domain definition: A:78-252 -> A:78-156,A:249-463 [64743]; A:157-248 [64742]
                1. region a:78-252 [24785] picpic
              4. 1fcf picpicxref
                cl=same,cf=same,sf=same,fa=68933,dm=68934,sp=same,px=64744
                cl=51349,cf=52095,sf=52096,fa=52100,dm=68935,sp=52102,px=64745
                modified domain definition: A:77-252 -> A:77-156,A:249-463 [64745]; A:157-248 [64744]
                1. region a:77-252 [24786] picpic
    4. OB-fold [50198] (1)
      1. Nucleic acid-binding proteins [50249] (1)
        1. Cold shock DNA-binding domain-like [50282] (1)
          1. Rho termination factor, N-terminal, RNA-binding domain [50294]
            1. Escherichia coli [50295] (7)
              1. 1a62 picpic
                cl=46456,cf=63450,sf=68912,fa=68913,dm=68914,sp=same,px=64708
                cl=same,cf=same,sf=same,fa=same,dm=68910,sp=68911,px=64709
                modified domain definition: - -> 1-47 [64708]; 48-125 [64709]
              2. 1a63 picpic
                cl=46456,cf=63450,sf=68912,fa=68913,dm=68914,sp=same,px=64710
                cl=same,cf=same,sf=same,fa=same,dm=68910,sp=68911,px=64711
                modified domain definition: - -> 1-47 [64710]; 48-130 [64711]
              3. 1a8v picpic
                cl=46456,cf=63450,sf=68912,fa=68913,dm=68914,sp=same,px=64712
                cl=same,cf=same,sf=same,fa=same,dm=68910,sp=68911,px=64713
                modified domain definition: A: -> A:-1-47 [64712]; A:48-118 [64713]
                1. chain a [25333] picpic
              4. 1a8v picpic
                cl=46456,cf=63450,sf=68912,fa=68913,dm=68914,sp=same,px=64714
                cl=same,cf=same,sf=same,fa=same,dm=68910,sp=68911,px=64715
                modified domain definition: B: -> B:-1-47 [64714]; B:48-118 [64715]
                1. chain b [25334] picpic
              5. 2a8v picpic
                cl=46456,cf=63450,sf=68912,fa=68913,dm=68914,sp=same,px=64752
                cl=same,cf=same,sf=same,fa=same,dm=68910,sp=68911,px=64753
                modified domain definition: A: -> A:1-47 [64752]; A:48-118 [64753]
                1. chain a [25335] picpic
              6. 2a8v picpic
                cl=46456,cf=63450,sf=68912,fa=68913,dm=68914,sp=same,px=64754
                cl=same,cf=same,sf=same,fa=same,dm=68910,sp=68911,px=64755
                modified domain definition: B: -> B:1-47 [64754]; B:48-118 [64755]
                1. chain b [25336] picpic
              7. 2a8v picpic
                cl=46456,cf=63450,sf=68912,fa=68913,dm=68914,sp=same,px=64756
                cl=same,cf=same,sf=same,fa=same,dm=68910,sp=68911,px=64757
                modified domain definition: C: -> C:1-47 [64756]; C:48-118 [64757]
                1. chain c [25337] picpic
    5. beta-clip [51268] (1)
      1. Molybdenum cofactor biosynthesis protein MoeA, C-terminal domain [63867] (1)
        1. Molybdenum cofactor biosynthesis protein MoeA, C-terminal domain [63868] (1)
          1. Molybdenum cofactor biosynthesis protein MoeA, C-terminal domain [63869]
            1. Escherichia coli [63870] (6)
              1. 1fc5 picpicxrefxref
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                modified domain definition: A:237-408 -> A:327-408 [59762]
                1. region a:237-408 [59762] picpic
              2. 1fc5 picpicxrefxref
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                modified domain definition: B:237-408 -> B:327-408 [59765]
                1. region b:237-408 [59765] picpic
              3. 1g8l picpicxrefxref
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                modified domain definition: A:237-409 -> A:327-409 [60365]
                1. region a:237-409 [60365] picpic
              4. 1g8l picpicxrefxref
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                modified domain definition: B:237-409 -> B:327-409 [60368]
                1. region b:237-409 [60368] picpic
              5. 1g8r picpicxrefxref
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                modified domain definition: A:237-409 -> A:327-409 [60377]
                1. region a:237-409 [60377] picpic
              6. 1g8r picpicxrefxref
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                modified domain definition: B:237-409 -> B:327-409 [60380]
                1. region b:237-409 [60380] picpic
  3. Alpha and beta proteins (a/b) [51349] (9)
    Mainly parallel beta sheets (beta-alpha-beta units)
    1. TIM beta/alpha-barrel [51350] (1)
      1. (Trans)glycosidases [51445] (1)
        1. beta-glycanases [51487] (1)
          1. Exo-beta-(1,3)-glucanase [51505]
            1. Yeast (Candida albicans) [51506] (1)
              1. 1cz1 picpic
                cl=same,cf=same,sf=same,fa=same,dm=51495,sp=51496,px=same
                1. chain a [28839] picpic
    2. ClpP/crotonase [52095] (1)
      1. ClpP/crotonase [52096] (1)
        1. Photosystem II D1 C-terminal processing protease, catalytic domain [52100] (1)
          1. Photosystem II D1 C-terminal processing protease, catalytic domain [52101]
            1. Algae (Scenedesmus obliquus) [52102] (4)
              1. 1fc6 picpicxref
                cl=48724,cf=50155,sf=50156,fa=68933,dm=68934,sp=50171,px=64738
                cl=same,cf=same,sf=same,fa=same,dm=68935,sp=same,px=64739
                modified domain definition: A:253-463 -> A:78-156,A:249-463 [64739]; A:157-248 [64738]
                1. region a:253-463 [30899] picpic
              2. 1fc7 picpicxref
                cl=48724,cf=50155,sf=50156,fa=68933,dm=68934,sp=50171,px=64740
                cl=same,cf=same,sf=same,fa=same,dm=68935,sp=same,px=64741
                modified domain definition: A:253-463 -> A:78-156,A:249-463 [64741]; A:157-248 [64740]
                1. region a:253-463 [30900] picpic
              3. 1fc9 picpicxref
                cl=48724,cf=50155,sf=50156,fa=68933,dm=68934,sp=50171,px=64742
                cl=same,cf=same,sf=same,fa=same,dm=68935,sp=same,px=64743
                modified domain definition: A:253-463 -> A:78-156,A:249-463 [64743]; A:157-248 [64742]
                1. region a:253-463 [30901] picpic
              4. 1fcf picpicxref
                cl=48724,cf=50155,sf=50156,fa=68933,dm=68934,sp=50171,px=64744
                cl=same,cf=same,sf=same,fa=same,dm=68935,sp=same,px=64745
                modified domain definition: A:253-463 -> A:77-156,A:249-463 [64745]; A:157-248 [64744]
                1. region a:253-463 [30902] picpic
    3. P-loop containing nucleotide triphosphate hydrolases [52539] (1)
      1. P-loop containing nucleotide triphosphate hydrolases [52540] (1)
        1. G proteins [52592] (1)
          1. Elongation factor Tu (EF-Tu), N-terminal (G) domain [52626]
            1. Escherichia coli [52627] (2)
              1. 1efm picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=64732
                modified domain definition: - -> 12-190 [64732]
              2. 1etu picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=64737
                modified domain definition: - -> 5-200 [64737]
    4. Thioredoxin fold [52832] (1)
      1. Thioredoxin-like 2Fe-2S ferredoxin [52917] (1)
        1. Thioredoxin-like 2Fe-2S ferredoxin [52918] (1)
          1. Thioredoxin-like 2Fe-2S ferredoxin [52919]
            1. Aquifex aeolicus [52920] (2)
              1. 1f37 picpic
                cl=same,cf=same,sf=52833,fa=same,dm=same,sp=same,px=same
                1. chain a [33088] picpic
              2. 1f37 picpic
                cl=same,cf=same,sf=52833,fa=same,dm=same,sp=same,px=same
                1. chain b [33089] picpic
    5. Ribonuclease H-like motif [53066] (1)
      1. Actin-like ATPase domain [53067] (1)
        1. Hexokinase [53083] (1)
          1. Hexokinase [53084]
            1. Baker's yeast (Saccharomyces cerevisiae), pII [64092] (1)
              1. 1ig8 picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=64746
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=64747
                modified domain definition: A: -> A:18-224 [64746]; A:225-486 [64747]
                1. chain a [62366] picpic
    6. Molybdenum cofactor biosynthesis proteins [53217] (1)
      1. Molybdenum cofactor biosynthesis proteins [53218] (1)
        1. MoeA, central domain [64103] (1)
          1. MoeA, central domain [64104]
            1. Escherichia coli [64105] (6)
              1. 1fc5 picpicxrefxref
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                modified domain definition: A:178-236 -> A:178-326 [59764]
                1. region a:178-236 [59764] picpic
              2. 1fc5 picpicxrefxref
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                modified domain definition: B:178-236 -> B:178-326 [59767]
                1. region b:178-236 [59767] picpic
              3. 1g8l picpicxrefxref
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                modified domain definition: A:178-236 -> A:178-326 [60367]
                1. region a:178-236 [60367] picpic
              4. 1g8l picpicxrefxref
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                modified domain definition: B:178-236 -> B:178-326 [60370]
                1. region b:178-236 [60370] picpic
              5. 1g8r picpicxrefxref
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                modified domain definition: A:178-236 -> A:178-326 [60379]
                1. region a:178-236 [60379] picpic
              6. 1g8r picpicxrefxref
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                modified domain definition: B:178-236 -> B:178-326 [60382]
                1. region b:178-236 [60382] picpic
    7. S-adenosyl-L-methionine-dependent methyltransferases [53334] (1)
      1. S-adenosyl-L-methionine-dependent methyltransferases [53335] (1)
        1. Protein-L-isoaspartate O-methyltransferase [53354] (1)
          1. Protein-L-isoaspartate O-methyltransferase [53355]
            1. Thermotoga maritima [53356] (2)
              1. 1dl5 picpic
                cl=same,cf=same,sf=same,fa=same,dm=68927,sp=68928,px=64720
                cl=53931,cf=68929,sf=68930,fa=68931,dm=68932,sp=same,px=64721
                modified domain definition: A: -> A:1-213 [64720]; A:214-317 [64721]
                1. chain a [34201] picpic
              2. 1dl5 picpic
                cl=same,cf=same,sf=same,fa=same,dm=68927,sp=68928,px=64722
                cl=53931,cf=68929,sf=68930,fa=68931,dm=68932,sp=same,px=64723
                modified domain definition: B: -> B:1-213 [64722]; B:214-316 [64723]
                1. chain b [34202] picpic
    8. Nucleotide-diphospho-sugar transferases [53447] (1)
      1. Nucleotide-diphospho-sugar transferases [53448] (2)
        1. 4-diphosphocytidyl-2-c-methylerythritol (CDP-me) synthase (YgbP) [64139] (1)
          1. 4-diphosphocytidyl-2-c-methylerythritol (CDP-me) synthase (YgbP) [64140]
            1. Escherichia coli [64141] (2)
              1. 1i52 picpic
                cl=same,cf=same,sf=same,fa=68901,dm=same,sp=same,px=same
                1. chain a [61767] picpic
              2. 1inj picpic
                cl=same,cf=same,sf=same,fa=68901,dm=same,sp=same,px=same
                1. chain a [62607] picpic
        2. CMP:2-keto-3-deoxy-manno-octonic acid (CMP-KDO)synthetase, KdsB [64142] (1)
          1. CMP:2-keto-3-deoxy-manno-octonic acid (CMP-KDO)synthetase, KdsB [64143]
            1. Escherichia coli [64144] (12)
              1. 1h6j picpic
                cl=same,cf=same,sf=same,fa=68901,dm=same,sp=same,px=same
                1. chain a [60673] picpic
              2. 1h6j picpic
                cl=same,cf=same,sf=same,fa=68901,dm=same,sp=same,px=same
                1. chain b [60674] picpic
              3. 1h7e picpic
                cl=same,cf=same,sf=same,fa=68901,dm=same,sp=same,px=same
                1. chain a [60717] picpic
              4. 1h7e picpic
                cl=same,cf=same,sf=same,fa=68901,dm=same,sp=same,px=same
                1. chain b [60718] picpic
              5. 1h7f picpic
                cl=same,cf=same,sf=same,fa=68901,dm=same,sp=same,px=same
                1. chain a [60719] picpic
              6. 1h7f picpic
                cl=same,cf=same,sf=same,fa=68901,dm=same,sp=same,px=same
                1. chain b [60720] picpic
              7. 1h7g picpic
                cl=same,cf=same,sf=same,fa=68901,dm=same,sp=same,px=same
                1. chain a [60721] picpic
              8. 1h7g picpic
                cl=same,cf=same,sf=same,fa=68901,dm=same,sp=same,px=same
                1. chain b [60722] picpic
              9. 1h7h picpic
                cl=same,cf=same,sf=same,fa=68901,dm=same,sp=same,px=same
                1. chain a [60723] picpic
              10. 1h7h picpic
                cl=same,cf=same,sf=same,fa=68901,dm=same,sp=same,px=same
                1. chain b [60724] picpic
              11. 1h7t picpic
                cl=same,cf=same,sf=same,fa=68901,dm=same,sp=same,px=same
                1. chain a [60730] picpic
              12. 1h7t picpic
                cl=same,cf=same,sf=same,fa=68901,dm=same,sp=same,px=same
                1. chain b [60731] picpic
    9. PEP carboxykinase-like [53794] (1)
      1. PEP carboxykinase-like [53795] (1)
        1. Phosphoenolpyruvate (PEP) carboxykinase (ATP-oxaloacetate carboxy-liase) [53796] (1)
          1. Phosphoenolpyruvate (PEP) carboxykinase (ATP-oxaloacetate carboxy-liase) [53797]
            1. Escherichia coli [53798] (3)
              1. 1aq2 picpic
                cl=same,cf=same,sf=same,fa=same,dm=68921,sp=same,px=64716
                cl=same,cf=68922,sf=68923,fa=68924,dm=68925,sp=68926,px=64717
                modified domain definition: - -> 4-227 [64717]; 228-540 [64716]
              2. 1ayl picpic
                cl=same,cf=68922,sf=68923,fa=68924,dm=68925,sp=68926,px=64719
                cl=same,cf=same,sf=same,fa=same,dm=68921,sp=same,px=64718
                modified domain definition: - -> 1-227 [64719]; 228-540 [64718]
              3. 1oen picpic
                cl=same,cf=same,sf=same,fa=same,dm=68921,sp=same,px=64750
                cl=same,cf=68922,sf=68923,fa=68924,dm=68925,sp=68926,px=64751
                modified domain definition: - -> 6-227 [64751]; 228-540 [64750]
  4. Alpha and beta proteins (a+b) [53931] (3)
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
    1. His-Me finger endonucleases [54059] (1)
      1. His-Me finger endonucleases [54060] (1)
        1. Recombination endonuclease VII [54072] (1)
          1. Recombination endonuclease VII [54073]
            1. Bacteriophage T4 [54074] (6)
              1. 1e7d picpic
                cl=same,cf=same,sf=same,fa=68915,dm=68916,sp=68917,px=64725
                cl=46456,cf=63450,sf=68918,fa=68919,dm=68920,sp=same,px=64724
                modified domain definition: A: -> A:1-103 [64725]; A:104-157 [64724]
                1. chain a [59342] picpic
              2. 1e7d picpic
                cl=same,cf=same,sf=same,fa=68915,dm=68916,sp=68917,px=64727
                cl=46456,cf=63450,sf=68918,fa=68919,dm=68920,sp=same,px=64726
                modified domain definition: B: -> B:1-103 [64727]; B:104-157 [64726]
                1. chain b [59343] picpic
              3. 1e7l picpic
                cl=same,cf=same,sf=same,fa=68915,dm=68916,sp=68917,px=64729
                cl=46456,cf=63450,sf=68918,fa=68919,dm=68920,sp=same,px=64728
                modified domain definition: A: -> A:1-103 [64729]; A:104-157 [64728]
                1. chain a [59345] picpic
              4. 1e7l picpic
                cl=same,cf=same,sf=same,fa=68915,dm=68916,sp=68917,px=64731
                cl=46456,cf=63450,sf=68918,fa=68919,dm=68920,sp=same,px=64730
                modified domain definition: B: -> B:1-103 [64731]; B:104-157 [64730]
                1. chain b [59346] picpic
              5. 1en7 picpic
                cl=same,cf=same,sf=same,fa=68915,dm=68916,sp=68917,px=64734
                cl=46456,cf=63450,sf=68918,fa=68919,dm=68920,sp=same,px=64733
                modified domain definition: A: -> A:1-103 [64734]; A:104-157 [64733]
                1. chain a [37161] picpic
              6. 1en7 picpic
                cl=same,cf=same,sf=same,fa=68915,dm=68916,sp=68917,px=64736
                cl=46456,cf=63450,sf=68918,fa=68919,dm=68920,sp=same,px=64735
                modified domain definition: B: -> B:1-103 [64736]; B:104-157 [64735]
                1. chain b [37162] picpic
    2. KH-domain [54790] (1)
      1. KH-domain [54791] (1)
        1. KH-domain [54792] (1)
          1. Polynucleotide phosphorylase/guanosine pentaphospate synthase (PNPase/GPSI), domain 6 [54803]
            1. Streptomyces antibioticus [54804] (2)
              1. 1e3h picpic
                cl=same,cf=54805,sf=54814,fa=54815,dm=same,sp=same,px=same
                1. region a:579-632 [38810] picpic
              2. 1e3p picpic
                cl=same,cf=54805,sf=54814,fa=54815,dm=same,sp=same,px=same
                1. region a:579-634 [38811] picpic
    3. Fibrinogen C-terminal domains [56495] (1)
      1. Fibrinogen C-terminal domains [56496] (1)
        1. Fibrinogen C-terminal domains [56497] (1)
          1. Fibrinogen C-terminal domains [56498]
            1. Human (Homo sapiens), beta and gamma [56499] (30)
              1. 1fib picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68904,px=same
              2. 1fic picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68904,px=same
                1. chain a [42458] picpic
              3. 1fic picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68904,px=same
                1. chain b [42459] picpic
              4. 1fid picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68904,px=same
              5. 1fza picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68903,px=same
                1. region b:200-460 [42480] picpic
              6. 1fza picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68903,px=same
                1. region e:200-460 [42482] picpic
              7. 1fza picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68904,px=same
                1. region c:142-396 [42481] picpic
              8. 1fza picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68904,px=same
                1. region f:142-396 [42483] picpic
              9. 1fzb picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68903,px=same
                1. region b:200-459 [42472] picpic
              10. 1fzb picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68903,px=same
                1. region e:200-459 [42474] picpic
              11. 1fzb picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68904,px=same
                1. region c:142-396 [42473] picpic
              12. 1fzb picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68904,px=same
                1. region f:142-398 [42475] picpic
              13. 1fzc picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68903,px=same
                1. region b:200-458 [42460] picpic
              14. 1fzc picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68903,px=same
                1. region e:200-458 [42462] picpic
              15. 1fzc picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68904,px=same
                1. region c:142-397 [42461] picpic
              16. 1fzc picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68904,px=same
                1. region f:142-397 [42463] picpic
              17. 1fze picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68903,px=same
                1. region b:200-459 [42476] picpic
              18. 1fze picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68903,px=same
                1. region e:200-458 [42478] picpic
              19. 1fze picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68904,px=same
                1. region c:142-394 [42477] picpic
              20. 1fze picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68904,px=same
                1. region f:142-393 [42479] picpic
              21. 1fzf picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68903,px=same
                1. region b:200-459 [42464] picpic
              22. 1fzf picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68903,px=same
                1. region e:200-459 [42466] picpic
              23. 1fzf picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68904,px=same
                1. region c:142-393 [42465] picpic
              24. 1fzf picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68904,px=same
                1. region f:142-393 [42467] picpic
              25. 1fzg picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68903,px=same
                1. region b:200-459 [42468] picpic
              26. 1fzg picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68903,px=same
                1. region e:200-459 [42470] picpic
              27. 1fzg picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68904,px=same
                1. region c:142-393 [42469] picpic
              28. 1fzg picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68904,px=same
                1. region f:142-393 [42471] picpic
              29. 2fib picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68904,px=same
                1. chain a [42457] picpic
              30. 3fib picpic
                cl=same,cf=same,sf=same,fa=same,dm=same,sp=68904,px=same
  5. Multi-domain proteins (alpha and beta) [56572] (2)
    Folds consisting of two or more domains belonging to different classes
    1. Ku heterodimer subunits [64500] (1)
      1. Ku heterodimer subunits [64501] (1)
        1. Ku70 subunit [64502] (1)
          1. Ku70 subunit [64503]
            1. Human (Homo sapiens) [64504] (2)
              1. 1jeq picpic
                cl=same,cf=same,sf=same,fa=same,dm=68905,sp=same,px=64749
                cl=46456,cf=63450,sf=68906,fa=68907,dm=68908,sp=68909,px=64748
                modified domain definition: A: -> A:35-538 [64749]; A:559-609 [64748]
                1. chain a [62921] picpic
              2. 1jey picpic
                cl=same,cf=same,sf=same,fa=same,dm=68905,sp=same,px=same
                1. chain a [62924] picpic
    2. HAD-like [56783] (1)
      1. HAD-like [56784] (4)
        1. L-2-Haloacid dehalogenase, HAD [56785] (2)
          1. L-2-Haloacid dehalogenase, HAD [56786]
            1. Pseudomonas sp., strain YL [56787] (4)
              1. 1jud picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
              2. 1qh9 picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. chain a [43326] picpic
              3. 1zrm picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
              4. 1zrn picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
            2. Xanthobacter autotrophicus [56788] (8)
              1. 1aq6 picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. chain a [43331] picpic
              2. 1aq6 picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. chain b [43332] picpic
              3. 1qq5 picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. chain a [43327] picpic
              4. 1qq5 picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. chain b [43328] picpic
              5. 1qq6 picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. chain a [43333] picpic
              6. 1qq6 picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. chain b [43334] picpic
              7. 1qq7 picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. chain a [43329] picpic
              8. 1qq7 picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. chain b [43330] picpic
        2. Epoxide hydrolase, N-terminal domain [56789] (1)
          1. Epoxide hydrolase, N-terminal domain [56790]
            1. Mouse (Mus musculus) [56791] (8)
              1. 1cqz picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. region a:4-225 [43339] picpic
              2. 1cqz picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. region b:4-225 [43340] picpic
              3. 1cr6 picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. region a:4-225 [43337] picpic
              4. 1cr6 picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. region b:4-225 [43338] picpic
              5. 1ek1 picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. region a:4-225 [43335] picpic
              6. 1ek1 picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. region b:4-225 [43336] picpic
              7. 1ek2 picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. region a:4-225 [43341] picpic
              8. 1ek2 picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. region b:4-225 [43342] picpic
        3. Phosphonoacetaldehyde hydrolase [56792] (1)
          1. Phosphonoacetaldehyde hydrolase [56793]
            1. Bacillus cereus [56794] (4)
              1. 1fez picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. chain a [43343] picpic
              2. 1fez picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. chain b [43344] picpic
              3. 1fez picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. chain c [43345] picpic
              4. 1fez picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. chain d [43346] picpic
        4. Phosphoserine phosphatase [64511] (1)
          1. Phosphoserine phosphatase [64512]
            1. Archaeon Methanococcus jannaschii [64513] (4)
              1. 1f5s picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. chain a [59656] picpic
              2. 1f5s picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. chain b [59657] picpic
              3. 1j97 picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. chain a [62753] picpic
              4. 1j97 picpic
                cl=51349,cf=same,sf=same,fa=same,dm=same,sp=same,px=same
                1. chain b [62754] picpic
  6. Membrane and cell surface proteins and peptides [56835] (0)
    Does not include proteins in the immune system
  7. Small proteins [56992] (0)
    Usually dominated by metal ligand, heme, and/or disulfide bridges
  8. Coiled coil proteins [57942] (0)
    Not a true class
  9. Low resolution protein structures [58117] (0)
    Not a true class
  10. Peptides [58231] (0)
    Peptides and fragments. Not a true class
  11. Designed proteins [58788] (0)
    Experimental structures of proteins with essentially non-natural sequences. Not a true class
  12. Non-protein [0] (0)
    PDB entries which are theoretical models, nucleic acids, or other non-proteins
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Generated from scop database 1.57_1.59 history with scopm 1.100 on Mon Jan 26 17:21:24 2004
Copyright © 1994-2003 The scop authors / scop@mrc-lmb.cam.ac.uk