Structural Classification of Proteins
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Changes in domain definitions and classification
Release 1.55 ---> 1.57

Root: scop

Classes:

  1. All alpha proteins [46456] (4)
    1. Globin-like [46457] (1)
      1. Globin-like [46458] (2)
        1. Globins [46463] (1)
          1. Hemoglobin, alpha-chain [46486]
            1. Human (Homo sapiens) [46487] (4) picpic
        2. Phycocyanins [46532] (1)
          1. C-phycocyanin [46535]
            1. Cyanobacterium (Fremyella diplosiphon) [46536] (4) picpic
    2. DNA/RNA-binding 3-helical bundle [46688] (1)
      1. TnsA endonuclease, C-terminal domain [46781] (1)
        1. TnsA endonuclease, C-terminal domain [46782] (1)
          1. TnsA endonuclease, C-terminal domain [46783]
            1. Escherichia coli [46784] (2) picpic
    3. Thermolysin-like metalloproteases, C-terminal domain [47900] (1)
      1. Thermolysin-like metalloproteases, C-terminal domain [47901] (1)
        1. Thermolysin-like metalloproteases, C-terminal domain [47902] (4)
          1. Elastase [47903]
            1. Pseudomonas aeruginosa [47904] (1) picpic
          2. Thermolysin [47905]
            1. Bacillus thermoproteolyticus [47906] (34) picpic
          3. Neutral protease [47907]
            1. Bacillus cereus, strain dsm 3101 [47908] (2) picpic
          4. Aureolysin [47909]
            1. Staphylococcus aureus [47910] (1) picpic
    4. Pleiotropic regulator of virulence genes, SarA [48289] (1)
      1. Pleiotropic regulator of virulence genes, SarA [48290] (1)
        1. Pleiotropic regulator of virulence genes, SarA [48291] (1)
          1. Pleiotropic regulator of virulence genes, SarA [48292]
            1. Staphylococcus aureus [48293] (3) picpic
  2. All beta proteins [48724] (8)
    1. Immunoglobulin-like beta-sandwich [48725] (1)
      1. Immunoglobulin [48726] (1)
        1. C1 set domains (antibody constant domain-like) [48942] (1)
          1. Immunoglobulin (constant domains of L and H chains) [48972]
            1. Fab C3, neutralizing type 1 poliovirus, (mouse), kappa L chain [49017] (1) picpic
    2. Cupredoxins [49502] (1)
      1. Cupredoxins [49503] (1)
        1. Periplasmic domain of cytochrome c oxidase subunit II [49541] (1)
          1. Nitrous oxide reductase, C-terminal domain [49548]
            1. Pseudomonas nautica [49549] (6) picpic
    3. PNGase F-like [49741] (2)
      1. PHM/PNGase F [49742] (1)
        1. Peptidylglycine alpha-hydroxylating monooxygenase, PHM [49746] (1)
          1. Peptidylglycine alpha-hydroxylating monooxygenase, PHM [49747]
            1. Rat (Rattus norvegicus) [49748] (3) picpic
      2. Viral proteins [49749] (2)
        1. Coat protein p3 [49750] (1)
          1. Coat protein p3 [49751]
            1. Bacteriophage prd1 [49752] (9) picpic
        2. Adenovirus hexon [49753] (2)
          1. Adenovirus hexon [49754]
            1. Human adenovirus type 2 [49755] (1) picpic
            2. Human adenovirus type 5 [49756] (1) picpic
    4. Segmented RNA-genome viruses' proteins [49817] (1)
      1. Segmented RNA-genome viruses' proteins [49818] (1)
        1. Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein HEF1 [49826] (1)
          1. Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein HEF1 [49827]
            1. Influenza C virus [49828] (3) picpic
    5. OB-fold [50198] (1)
      1. MOP-like [50331] (2)
        1. C-terminal domain of molybdate-dependent transcriptional regulator ModE [50335] (1)
          1. C-terminal domain of molybdate-dependent transcriptional regulator ModE [50336]
            1. Escherichia coli [50337] (4) picpic
        2. Maltose transport protein MalK, C-terminal domain [50338] (1)
          1. Maltose transport protein MalK, C-terminal domain [50339]
            1. Archaea (Thermococcus litoralis) [50340] (2) picpic
    6. Reductase/isomerase/elongation factor common domain [50412] (1)
      1. Ferredoxin reductase-like, FAD-binding (N-terminal) domain [50413] (5)
        1. Reductases [50414] (10)
          1. Ferredoxin reductase (flavodoxin reductase) [50415]
            1. Spinach (Spinacia oleracea) [50416] (7) picpic
            2. Garden pea (Pisum sativum) [50417] (8) picpic
            3. Paprika (Capsicum annuum) [50418] (2) picpic
            4. Maize (Zea mays) [50419] (4) picpic
            5. Cyanobacterium (Anabaena sp.), pcc 7119 [50420] (6) picpic
            6. Escherichia coli [50421] (1) picpic
            7. Azotobacter vinelandii [50422] (1) picpic
          2. NAD(P)H:flavin oxidoreductase [50423]
            1. Escherichia coli [50424] (4) picpic
          3. Nitrate reductase core domain [50425]
            1. Corn (Zea mays) [50426] (3) picpic
          4. cytochrome b5 reductase [50427]
            1. Pig (Sus scrofa), liver [50428] (1) picpic
        2. Phthalate dioxygenase reductase [50429] (1)
          1. Phthalate dioxygenase reductase [50430]
            1. Pseudomonas cepacia, db01 [50431] (1) picpic
        3. Dihydroorotate dehydrogenase B, PyrK subunit [50432] (1)
          1. Dihydroorotate dehydrogenase B, PyrK subunit [50433]
            1. Lactococcus lactis, isozyme B [50434] (3) picpic
        4. Flavohemoglobin, central domain [50435] (1)
          1. Flavohemoglobin, central domain [50436]
            1. Alcaligenes eutrophus [50437] (2) picpic
        5. NADPH-cytochrome p450 reductase-like [50438] (2)
          1. NADPH-cytochrome p450 reductase [50439]
            1. Rat (Rattus norvegicus) [50440] (2) picpic
          2. Sulfite reductase flavoprotein [50441]
            1. Escherichia coli [50442] (3) picpic
    7. Single-stranded right-handed beta-helix [51125] (1)
      1. Pectin lyase-like [51126] (1)
        1. Galacturonase [51137] (1)
          1. Endo-polygalacturonase II [51142]
            1. Fungus (Aspergillus niger) [51143] (2) picpic
    8. Double-stranded beta-helix [51181] (1)
      1. cAMP-binding domain-like [51206] (1)
        1. cAMP-binding domain [51210] (1)
          1. Regulatory subunit of Protein kinase A [51213]
            1. Cow (Bos taurus) [51214] (2) picpic
  3. Alpha and beta proteins (a/b) [51349] (6)
    Mainly parallel beta sheets (beta-alpha-beta units)
    1. Flavodoxin-like [52171] (1)
      1. Esterase/acetylhydrolase [52266] (1)
        1. Esterase domain of haemagglutinin-esterase-fusion glycoprotein HEF1 [52270] (1)
          1. Esterase domain of haemagglutinin-esterase-fusion glycoprotein HEF1 [52271]
            1. Influenza C virus [52272] (3) picpic
    2. P-loop containing nucleotide triphosphate hydrolases [52539] (1)
      1. P-loop containing nucleotide triphosphate hydrolases [52540] (1)
        1. Extended AAA-ATPase domain [52700] (1)
          1. DEXX box DNA helicase [52701]
            1. Bacillus stearothermophilus, PcrA [52702] (1) picpic
    3. (Phosphotyrosine protein) phosphatases II [52798] (1)
      1. (Phosphotyrosine protein) phosphatases II [52799] (1)
        1. Phoshphoinositide phosphatase Pten (Pten tumor suppressor), N-terminal domain [52817] (1)
          1. Phoshphoinositide phosphatase Pten (Pten tumor suppressor), N-terminal domain [52818]
            1. Human (Homo sapiens) [52819] (1) picpic
    4. alpha/beta-Hydrolases [53473] (1)
      1. alpha/beta-Hydrolases [53474] (1)
        1. Bacterial lipase [53570] (2)
          1. Lipase [53571]
            1. Pseudomonas cepacia [53573] (4) picpic
            2. Pseudomona sp., ATCC 21808 [53574] (3) picpic
    5. Ribokinase-like [53612] (1)
      1. MurD-like peptide ligases, catalytic domain [53623] (1)
        1. MurD/MurF [53624] (1)
          1. MurF (UDP-murNac-tripeptide D-alanyl-D-alanine-adding enzyme) [53627]
            1. Escherichia coli [53628] (2) picpic
    6. Thiolase-like [53900] (1)
      1. Thiolase-like [53901] (1)
        1. Thiolase-related [53902] (1)
          1. Beta-ketoacyl-ACP synthase II [53909]
            1. Synechocystis sp. [53911] (1) picpic
  4. Alpha and beta proteins (a+b) [53931] (5)
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
    1. Elongation factor Ts (EF-Ts), dimerisation domain [54712] (1)
      1. Elongation factor Ts (EF-Ts), dimerisation domain [54713] (1)
        1. Elongation factor Ts (EF-Ts), dimerisation domain [54714] (2)
          1. Elongation factor Ts (EF-Ts), dimerisation domain [54715]
            1. Escherichia coli [54716] (4) picpic
            2. Thermus thermophilus [54717] (5) picpic
    2. Zincin-like [55485] (1)
      1. Metalloproteases ("zincins"), catalytic domain [55486] (2)
        1. Thermolysin-like [55490] (4)
          1. Elastase [55491]
            1. Pseudomonas aeruginosa [55492] (1) picpic
          2. Thermolysin [55493]
            1. Bacillus thermoproteolyticus [55494] (32) picpic
          3. Neutral protease [55495]
            1. Bacillus cereus, strain dsm 3101 [55496] (2) picpic
          4. Aureolysin [55497]
            1. Staphylococcus aureus [55498] (1) picpic
        2. Matrix metalloproteases, catalytic domain [55528] (2)
          1. Gelatinase A [55534]
            1. Human (Homo sapiens) [55535] (1) picpic
          2. Stromelysin-1 (MMP-3) [55536]
            1. Human (Homo sapiens), fibroblast [55537] (1) picpic
    3. Mitochondrial processing peptidase, MPP [55993] (1)
      1. Mitochondrial processing peptidase, MPP [55994] (1)
        1. Cytochrome bc1 core subunits [55995] (4)
          1. Core 1 subunit [55996]
            1. Cow (Bos taurus) [55997] (4) picpic
            2. Chicken (Gallus gallus) [55998] (3) picpic
          2. Core 2 subunit [55999]
            1. Cow (Bos taurus) [56000] (4) picpic
            2. Chicken (Gallus gallus) [56001] (3) picpic
    4. 4'-Phosphopantetheinyl transferase SFP [56213] (1)
      1. 4'-Phosphopantetheinyl transferase SFP [56214] (1)
        1. 4'-Phosphopantetheinyl transferase SFP [56215] (1)
          1. 4'-Phosphopantetheinyl transferase SFP [56216]
            1. Bacillus subtilis [56217] (1) picpic
    5. Fumarylacetoacetate hydrolase, FAH [56528] (1)
      1. Fumarylacetoacetate hydrolase, FAH [56529] (1)
        1. Fumarylacetoacetate hydrolase, FAH [56530] (1)
          1. Fumarylacetoacetate hydrolase, FAH [56531]
            1. Mouse (Mus musculus) [56532] (8) picpic
  5. Multi-domain proteins (alpha and beta) [56572] (0)
    Folds consisting of two or more domains belonging to different classes
  6. Membrane and cell surface proteins and peptides [56835] (1)
    Does not include proteins in the immune system
    1. Membrane all-alpha [56868] (1)
      1. Membrane all-alpha [56869] (2)
        1. Potassium chanel protein [56900] (1)
          1. Potassium chanel protein [56901]
            1. Streptomyces lividans [56902] (8) picpic
        2. Gated mechanosensitive channel [56903] (1)
          1. Gated mechanosensitive channel [56904]
            1. Mycobacterium tuberculosis [56905] (5) picpic
  7. Small proteins [56992] (4)
    Usually dominated by metal ligand, heme, and/or disulfide bridges
    1. Defensin-like [57391] (1)
      1. Defensin-like [57392] (1)
        1. Defensin [57393] (2)
          1. Beta-defensin 2 [57396]
            1. Human (Homo sapiens) [57397] (20) picpic
          2. Beta-defensin 12 [57398]
            1. Cow (Bos taurus) [57399] (1) picpic
    2. Kringle-like [57439] (1)
      1. Kringle-like [57440] (1)
        1. Kringle modules [57441] (2)
          1. Plasminogen kringle 4 [57442]
            1. Human (Homo sapiens) [57443] (8) picpic
          2. Plasminogen kringle 2 [57444]
            1. Human (Homo sapiens) [57445] (5) picpic
    3. Cystine-knot cytokines [57500] (1)
      1. Cystine-knot cytokines [57501] (1)
        1. Gonadotropin, A and B chains [57528] (1)
          1. Gonadotropin, A and B chains [57529]
            1. Human (Homo sapiens) [57530] (8) picpic
    4. Rubredoxin-like [57769] (1)
      1. Zinc beta-ribbon [57783] (1)
        1. Transcriptional factor domain [57784] (1)
          1. Rbp9 subunit of RNA polymerase II, C-terminal domain [57787]
            1. Thermococcus celer [57788] (1) picpic
  8. Coiled coil proteins [57942] (0)
    Not a true class
  9. Low resolution protein structures [58117] (0)
    Not a true class
  10. Peptides [58231] (0)
    Peptides and fragments. Not a true class
  11. Designed proteins [58788] (0)
    Experimental structures of proteins with essentially non-natural sequences. Not a true class
  12. Non-protein [0] (0)
    PDB entries which are theoretical models, nucleic acids, or other non-proteins
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Generated from scop database 1.55_1.57 history with scopm 1.100 on Mon Jan 26 19:10:26 2004
Copyright © 1994-2003 The scop authors / scop@mrc-lmb.cam.ac.uk