Fold: Trefoil

disulphide-rich fold; duplication: consists of two homologous domains

Lineage:

1. Root: scop
2. Class: Small proteins
   Usually dominated by metal ligand, heme, and/or disulfide bridges
3. Fold: Trefoil
   disulphide-rich fold; duplication: consists of two homologous domains

Superfamilies:

1. Trefoil (1)
   1. Trefoil (3)
      1. Pancreatic spasmolytic polypeptide
         1. Pig (Sus scrofa) (4)
      2. PNR-2/PS2, TFF1
         single trefoil motif protein
         1. Human (Homo sapiens) (2)
      3. Intestinal trefoil factor
         1. Human (Homo sapiens) (1)