Fold: Membrane all-alpha

Lineage:

1. Root: scop
2. Class: Membrane and cell surface proteins and peptides
   Does not include proteins in the immune system
3. Fold: Membrane all-alpha

Superfamilies:

1. Membrane all-alpha (10)
   this is not a true superfamily family; in this provisional classification each transmembrane helix is considered to be a 'domain'
   1. Seven-helix membrane receptors (4)
      1. Bacteriorhodopsin
         a light-driven proton pump
         1. Halobacterium halobium (3)
         2. Halobacterium salinarum (19)
      2. Halorhodopsin
         a light-driven chloride pump
         1. Halobacterium salinarum (1)
      3. Rhodopsin
         1. Cow (Bos taurus) (1)
   2. Photosynthetic reaction centre, L-, M- and H-chains (3)
      1. Photosynthetic reaction centre, L-, M- and H-chains
         L and M are probably related to each other but not to H
         1. Rhodopseudomonas viridis (8)
         2. Rhodobacter sphaeroides (15)
         3. Thermochromatium tepidum (1)
   3. Cytochrome c oxidase-like (4)
      There are two common subunits shared by all members
      1. Cytochrome c oxidase
         1. Cow (Bos taurus) (5)
         2. Paracoccus denitrificans (2)
         3. Thermus thermophilus, ba3 type (1)
      2. Ubiquinol oxidase
         1. Escherichia coli (1)
   4. F1F0 ATP synthase subunits (2)
      1. Subunit C
         1. Escherichia coli (4)
      2. Subunit A
         1. Escherichia coli (1)
   5. Aquaporin-like (2)
      1. Aquaporin-1
         1. Human (Homo sapiens) (2)
      2. Glycerol uptake facilitator protein GlpF
         glycerol conducting channel, related to aquaporin
         1. Escherichia coli (1)
   6. Potassium chanel protein (1)
      1. Potassium chanel protein
         1. Streptomyces lividans (2)
   7. Gated mechanosensitive channel (1)
      1. Gated mechanosensitive channel
         1. Mycobacterium tuberculosis (1)
   8. Cytochrome bc1 transmembrane subunits (2)
      1. Cytochrome bc1 transmembrane subunits
         1. Cow (Bos taurus) (3)
         2. Chicken (Gallus gallus) (3)
   9. Fumarate reductase respiratory complex transmembrane subunits (2)
      1. Fumarate reductase respiratory complex transmembrane subunits
         1. Escherichia coli (1)
         2. Wolinella succinogenes (2)
   10. Calcium ATPase (1)
       1. Calcium ATPase
          Provisional classification: cytoplasmic domains will be cut out and classified in future release
          the catalytic domain is homologous to the catalytic domain of L-2-Haloacid dehalogenase (e.g. 1QQ5)
          1. Rabbit (Oryctolagus cuniculus) (1)