Fold: Nucleotidyltransferases

common catalytic domain is alpha+beta; 2 layers: a/b; mixed sheet

Lineage:

1. Root: scop
2. Class: Multi-domain proteins (alpha and beta)
   Folds consisting of two or more domains belonging to different classes
3. Fold: Nucleotidyltransferases
   common catalytic domain is alpha+beta; 2 layers: a/b; mixed sheet

Superfamilies:

1. Nucleotidyltransferases (3)
   1. DNA polymerase beta, catalytic (31 kD) fragment (2)
      catalytic domain is between all-alpha and alpha+beta domains
      1. DNA polymerase beta, catalytic (31 kD) fragment
         1. Human (Homo sapiens) (90)
         2. Rat (Rattus norvegicus) (15)
   2. Poly(A) polymerase, catalytic domain (2)
      1. Poly(A) polymerase, catalytic domain
         1. Baker's yeast (Saccharomyces cerevisiae) (1)
         2. Cow (Bos taurus) (1)
   3. Kanamycin nucleotidyltransferase (KNTase) (1)
      N-terminal catalytic domain is followed by an all-alpha domain
      1. Kanamycin nucleotidyltransferase (KNTase)
         1. Staphylococcus aureus (2)