Fold: Bactericidal permeability-increasing protein, BPI

beta-alpha-beta(5)-alpha-beta2; 2 layers: alpha/beta; antiparallel sheet

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a+b)
   Mainly antiparallel beta sheets (segregated alpha and beta regions)
3. Fold: Bactericidal permeability-increasing protein, BPI
   beta-alpha-beta(5)-alpha-beta2; 2 layers: alpha/beta; antiparallel sheet

Superfamilies:

1. Bactericidal permeability-increasing protein, BPI (1)
   duplication: consists of two clear structural repeats of this fold
   1. Bactericidal permeability-increasing protein, BPI (1)
      1. Bactericidal permeability-increasing protein, BPI
         1. Human (Homo sapiens) (2)
            1. 1ewf
               complexed with pc2; mutant
               1. region a:1-217
               2. region a:218-456
            2. 1bp1
               CASP2
               complexed with pc; mutant
               1. region 1-217
               2. region 218-456