Fold: Cystatin-like

Core: alpha-beta(4); helix packs against coiled antiparallel beta-sheet

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a+b)
   Mainly antiparallel beta sheets (segregated alpha and beta regions)
3. Fold: Cystatin-like
   Core: alpha-beta(4); helix packs against coiled antiparallel beta-sheet

Superfamilies:

1. Cystatin/monellin (2)
   has a additional strand at the N-terminus
2. Copper amine oxidase, domains 1 and 2 (1)
3. Disulfide bond isomerase, DsbC, N-terminal domain (1)
4. NTF2-like (4)
   has a beta-alpha(2)-beta insertion after the main helix
5. Uracil-DNA glycosylase inhibitor protein (1)
   has an additional strand at the C-terminus and a helix inserted after the first strand