Fold: Metallo-hydrolase/oxidoreductase

duplication of beta(4)-alpha-beta-alpha motif; 4 layers a/b/b/a; mixed beta-sheets

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a+b)
   Mainly antiparallel beta sheets (segregated alpha and beta regions)
3. Fold: Metallo-hydrolase/oxidoreductase
   duplication of beta(4)-alpha-beta-alpha motif; 4 layers a/b/b/a; mixed beta-sheets

Superfamilies:

1. Metallo-hydrolase/oxidoreductase (3)
   1. Zn metallo-beta-lactamase (4)
   2. Glyoxalase II (hydroxyacylglutathione hydrolase) (1)
   3. Rubredoxin oxygen:oxidoreductase (ROO), N-terminal domain (1)