Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase

8-stranded mixed beta-sheet; 2 layers: alpha/beta

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a+b)
   Mainly antiparallel beta sheets (segregated alpha and beta regions)
3. Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

Superfamilies:

1. ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase (3)
   1. Heat shock protein 90, HSP90, N-terminal domain (2)
   2. DNA gyrase/MutL, N-terminal domain (2)
   3. Histidine kinase (2)