Fold: Actin depolymerizing proteins

3 layers: a/b/a; contains mixed beta-sheet

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a+b)
   Mainly antiparallel beta sheets (segregated alpha and beta regions)
3. Fold: Actin depolymerizing proteins
   3 layers: a/b/a; contains mixed beta-sheet

Superfamilies:

1. Actin depolymerizing proteins (2)
   1. Gelsolin-like (4)
   2. Cofilin-like (4)