Fold: Isocitrate & isopropylmalate dehydrogenases

consists of two intertwined (sub)domains related by pseudodyad; duplication
3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a/b)
   Mainly parallel beta sheets (beta-alpha-beta units)
3. Fold: Isocitrate & isopropylmalate dehydrogenases
   consists of two intertwined (sub)domains related by pseudodyad; duplication
   3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

Superfamilies:

1. Isocitrate & isopropylmalate dehydrogenases (1)
   1. Isocitrate & isopropylmalate dehydrogenases (7)
      1. 3-isopropylmalate dehydrogenase, IPMDH
         1. Thermus thermophilus (14)
         2. Chimera (Thermus thermophilus) and (Bacillus subtilis) (2)
         3. Bacillus coagulans (1)
         4. Thiobacillus ferrooxidans (1)
         5. Salmonella typhimurium (1)
         6. Escherichia coli (1)
      2. Isocitrate dehydrogenase, ICDH
         1. Escherichia coli (23)