Fold: Thioredoxin fold

core: 3 layers, a/b/a; mixed beta-sheet of 4 strands, order 4312; strand 3 is antiparallel to the rest

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a/b)
   Mainly parallel beta sheets (beta-alpha-beta units)
3. Fold: Thioredoxin fold
   core: 3 layers, a/b/a; mixed beta-sheet of 4 strands, order 4312; strand 3 is antiparallel to the rest

Superfamilies:

1. Thioredoxin-like (10)
2. RNA 3'-terminal phosphate cyclase, RPTC, insert domain (1)
3. Thioredoxin-like 2Fe-2S ferredoxin (1)