Fold: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases

core: 4 helices; bundle; one loop crosses over one side of the bundle

Lineage:

1. Root: scop
2. Class: All alpha proteins
3. Fold: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
   core: 4 helices; bundle; one loop crosses over one side of the bundle

Superfamilies:

1. Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases (1)
   1. Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases (6)
      1. Methionyl-tRNA synthetase (MetRS)
         this domain follows the Rossmann-fold catalytic domain of class I aaRS
         1. Thermus thermophilus (1)
         2. Escherichia coli (1)
      2. Isoleucyl-tRNA synthetase (IleRS)
         1. Thermus thermophilus (1)
         2. Staphylococcus aureus (3)
            contains additional alpha+beta and Zn-binding domains in the C-terminal extension
      3. Valyl-tRNA synthetase (ValRS)
         contains additional (sub)domains in the C-terminal extension
         1. Thermus thermophilus (1)
      4. Arginyl-tRNA synthetase (ArgRS)
         1. Baker's yeast (Saccharomyces cerevisiae) (1)