Fold: Nuclear receptor ligand-binding domain

multihelical; 3 layers or orthogonally packed helices

Lineage:

1. Root: scop
2. Class: All alpha proteins
3. Fold: Nuclear receptor ligand-binding domain
   multihelical; 3 layers or orthogonally packed helices

Superfamilies:

1. Nuclear receptor ligand-binding domain (1)
   1. Nuclear receptor ligand-binding domain (14)
      1. Retinoid-X receptor (RXR-alpha)
         1. Human (Homo sapiens) (4)
         2. Mouse (Mus musculus) (1)
      2. Retinoic acid receptor alpha (RAR-alpha)
         1. Human (Homo sapiens) (1)
      3. Retinoic acid receptor gamma (RAR-gamma)
         1. Human (Homo sapiens) (8)
      4. Progesterone receptor
         1. Human (Homo sapiens) (1)
      5. Estrogen receptor alpha
         1. Human (Homo sapiens) (7)
      6. Estrogen receptor beta
         1. Human (Homo sapiens) (1)
         2. Rat (Rattus norvegicus) (1)
      7. Peroxisome proliferator activated receptor gamma, PPAR-RXR
         1. Human (Homo sapiens) (6)
      8. Peroxisome proliferator-activated receptor delta, PPAR-DELTA
         1. Human (Homo sapiens) (3)
      9. Vitamin D nuclear receptor
         1. Human (Homo sapiens) (1)
      10. Thyroid hormone receptor beta (TR-beta)
          1. Human (Homo sapiens) (1)
      11. Thyroid hormone receptor alpha1 (TR-alpha1)
          1. Rat (Rattus norvegicus) (1)
      12. Ultraspiracle
          1. Drosophila melanogaster (1)