Fold: 6-phosphogluconate dehydrogenase C-terminal domain-like

multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold rotation

Lineage:

1. Root: scop
2. Class: All alpha proteins
3. Fold: 6-phosphogluconate dehydrogenase C-terminal domain-like
   multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold rotation

Superfamilies:

1. 6-phosphogluconate dehydrogenase C-terminal domain-like (6)
   N-terminal domain is Rossmann-fold with a family-specific C-terminal extension
   1. 6-phosphogluconate dehydrogenase (6PGD) (2)
   2. Acetohydroxy acid isomeroreductase, ketoacid reductoisomerase (KARI) (1)
   3. Short chain L-3-hydroxyacyl CoA dehydrogenase (2)
   4. UDP-glucose dehydrogenase (UDPGDH), middle domain (1)
   5. N-(1-D-carboxylethyl)-L-norvaline dehydrogenase (1)
   6. Glycerol-3- phosphate dehydrogenase (1)